Design of the First‐in‐Class, Highly Potent Irreversible Inhibitor Targeting the Menin‐MLL Protein–Protein Interaction
Xu, Shilin, Aguilar, Angelo, Xu, Tianfeng, Zheng, Ke, Huang, Liyue, Stuckey, Jeanne, Chinnaswamy, Krishnapriya, Bernard, Denzil, Fernández‐Salas, Ester, Liu, Liu, Wang, Mi, McEachern, Donna, Przybranowski, Sally, Foster, Caroline, Wang, Shaomeng
Published in Angewandte Chemie (International ed.) (05.02.2018)
Published in Angewandte Chemie (International ed.) (05.02.2018)
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Journal Article
Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay
Fernández-Salas, Ester, Wang, Joanne, Molina, Yanira, Nelson, Jeremy B, Jacky, Birgitte P S, Aoki, K Roger
Published in PloS one (21.11.2012)
Published in PloS one (21.11.2012)
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Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A)
Jacky, Birgitte P S, Garay, Patton E, Dupuy, Jérôme, Nelson, Jeremy B, Cai, Brian, Molina, Yanira, Wang, Joanne, Steward, Lance E, Broide, Ron S, Francis, Joseph, Aoki, K Roger, Stevens, Raymond C, Fernández-Salas, Ester
Published in PLoS pathogens (2013)
Published in PLoS pathogens (2013)
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Journal Article
A Highly Specific Monoclonal Antibody for Botulinum Neurotoxin Type A-Cleaved SNAP25
Rhéaume, Catherine, Cai, Brian B, Wang, Joanne, Fernández-Salas, Ester, Aoki, K Roger, Francis, Joseph, Broide, Ron S
Published in Toxins (24.06.2015)
Published in Toxins (24.06.2015)
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Journal Article
Plasma Membrane Localization Signals in the Light Chain of Botulinum Neurotoxin
Fernández-Salas, Ester, Steward, Lance E., Ho, Helen, Garay, Patton E., Sun, Sarah W., Gilmore, Marcella A., Ordas, Joseph V., Wang, Joanne, Francis, Joseph, Aoki, K. Roger, Boyer, Herbert W.
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
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mtCLIC/CLIC4, an Organellular Chloride Channel Protein, Is Increased by DNA Damage and Participates in the Apoptotic Response to p53
Fernández-Salas, Ester, Suh, Kwang S., Speransky, Vladislav V., Bowers, Wendy L., Levy, Joshua M., Adams, Tracey, Pathak, Kamal R., Edwards, Lindsay E., Hayes, Daniel D., Cheng, Christina, Steven, Alasdair C., Weinberg, Wendy C., Yuspa, Stuart H.
Published in Molecular and Cellular Biology (01.06.2002)
Published in Molecular and Cellular Biology (01.06.2002)
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Journal Article
Is the light chain subcellular localization an important factor in botulinum toxin duration of action?
Fernández-Salas, Ester, Ho, Helen, Garay, Patton, Steward, Lance E., Aoki, K. Roger
Published in Movement disorders (01.03.2004)
Published in Movement disorders (01.03.2004)
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Conference Proceeding
Novel Chimeras of Botulinum Neurotoxins A and E Unveil Contributions from the Binding, Translocation, and Protease Domains to Their Functional Characteristics
Wang, Jiafu, Meng, Jianghui, Lawrence, Gary W., Zurawski, Tomas H., Sasse, Astrid, Bodeker, MacDara O., Gilmore, Marcella A., Fernández-Salas, Ester, Francis, Joseph, Steward, Lance E., Aoki, K. Roger, Dolly, J. Oliver
Published in The Journal of biological chemistry (20.06.2008)
Published in The Journal of biological chemistry (20.06.2008)
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Journal Article
Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer
Han, Xin, Wang, Chao, Qin, Chong, Xiang, Weiguo, Fernandez-Salas, Ester, Yang, Chao-Yie, Wang, Mi, Zhao, Lijie, Xu, Tianfeng, Chinnaswamy, Krishnapriya, Delproposto, James, Stuckey, Jeanne, Wang, Shaomeng
Published in Journal of medicinal chemistry (24.01.2019)
Published in Journal of medicinal chemistry (24.01.2019)
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Journal Article
Design of the First‐in‐Class, Highly Potent Irreversible Inhibitor Targeting the Menin‐MLL Protein–Protein Interaction
Xu, Shilin, Aguilar, Angelo, Xu, Tianfeng, Zheng, Ke, Huang, Liyue, Stuckey, Jeanne, Chinnaswamy, Krishnapriya, Bernard, Denzil, Fernández‐Salas, Ester, Liu, Liu, Wang, Mi, McEachern, Donna, Przybranowski, Sally, Foster, Caroline, Wang, Shaomeng
Published in Angewandte Chemie (05.02.2018)
Published in Angewandte Chemie (05.02.2018)
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Journal Article
Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression
Qin, Chong, Hu, Yang, Zhou, Bing, Fernandez-Salas, Ester, Yang, Chao-Yie, Liu, Liu, McEachern, Donna, Przybranowski, Sally, Wang, Mi, Stuckey, Jeanne, Meagher, Jennifer, Bai, Longchuan, Chen, Zhuo, Lin, Mei, Yang, Jiuling, Ziazadeh, Danya N, Xu, Fuming, Hu, Jiantao, Xiang, Weiguo, Huang, Liyue, Li, Siwei, Wen, Bo, Sun, Duxin, Wang, Shaomeng
Published in Journal of medicinal chemistry (09.08.2018)
Published in Journal of medicinal chemistry (09.08.2018)
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Journal Article
Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment
Kregel, Steven, Wang, Chao, Han, Xin, Xiao, Lanbo, Fernandez-Salas, Ester, Bawa, Pushpinder, McCollum, Brooke L., Wilder-Romans, Kari, Apel, Ingrid J., Cao, Xuhong, Speers, Corey, Wang, Shaomeng, Chinnaiyan, Arul M.
Published in Neoplasia (New York, N.Y.) (01.02.2020)
Published in Neoplasia (New York, N.Y.) (01.02.2020)
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Journal Article
A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation
Zhou, Haibin, Lu, Jianfeng, Liu, Liu, Bernard, Denzil, Yang, Chao-Yie, Fernandez-Salas, Ester, Chinnaswamy, Krishnapriya, Layton, Stephanie, Stuckey, Jeanne, Yu, Qing, Zhou, Weihua, Pan, Zhenqiang, Sun, Yi, Wang, Shaomeng
Published in Nature communications (27.10.2017)
Published in Nature communications (27.10.2017)
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Journal Article
Septin Dynamics Are Essential for Exocytosis
Tokhtaeva, Elmira, Capri, Joe, Marcus, Elizabeth A., Whitelegge, Julian P., Khuzakhmetova, Venera, Bukharaeva, Ellya, Deiss-Yehiely, Nimrod, Dada, Laura A., Sachs, George, Fernandez-Salas, Ester, Vagin, Olga
Published in The Journal of biological chemistry (27.02.2015)
Published in The Journal of biological chemistry (27.02.2015)
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Journal Article
EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development
Rej, Rohan Kalyan, Wang, Changwei, Lu, Jianfeng, Wang, Mi, Petrunak, Elyse, Zawacki, Kaitlin P, McEachern, Donna, Fernandez-Salas, Ester, Yang, Chao-Yie, Wang, Lu, Li, Ruiting, Chinnaswamy, Krishnapriya, Wen, Bo, Sun, Duxin, Stuckey, Jeanne, Zhou, Yunlong, Chen, Jianyong, Tang, Guozhi, Wang, Shaomeng
Published in Journal of medicinal chemistry (09.07.2020)
Published in Journal of medicinal chemistry (09.07.2020)
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Journal Article
Corrigendum to ‘Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment’ Neoplasia, Volume 22, Issue 2 (2020) 111–119
Kregel, Steven, Wang, Chao, Han, Xin, Xiao, Lanbo, Fernandez-Salas, Ester, Bawa, Pushpinder, McCollum, Brooke L., Wilder-Romans, Kari, Apel, Ingrid J., Cao, Xuhong, Speers, Corey, Wang, Shaomeng, Chinnaiyan, Arul M.
Published in Neoplasia (New York, N.Y.) (01.05.2024)
Published in Neoplasia (New York, N.Y.) (01.05.2024)
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Journal Article
Ribonucleases expressed by human pancreatic adenocarcinoma cell lines
Fernández‐Salas, Ester, Peracaula, Rosa, Frazier, Marsha L., de Llorens, Rafael
Published in European journal of biochemistry (01.03.2000)
Published in European journal of biochemistry (01.03.2000)
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Journal Article
880 Inhibition of AXL signaling with AB801 augments anti-tumor immune responses
Leslie, Jhansi, Goshayeshi, Armon, Park, Eugene, Flores, Ruben, Barajas, Gonzalo, Schwager, Samantha C, Stagnaro, Enzo, Kaplan, Angelo, Kline, Janine, Fernandez-Salas, Ester, Paprcka, Susan L
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
787 AB598, a CD39 inhibitory antibody, promotes immune-mediated tumor control
Clor, Julie, Jin, Ke, Parashar, Kaustubh, Anderson, Amy E, Kates, Lance, Guan, Yihong, Schwager, Sam, Talukdar, Priyanka, Kushwaha, Ritu, Kline, Janine, Fernandez-Salas, Ester, Bowman, Christine
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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