Early Clinical Experience With AZD4831, A Novel Myeloperoxidase Inhibitor, Developed for Patients With Heart Failure With Preserved Ejection Fraction
Nelander, Karin, Lagerstrom‐Fermer, Maria, Amilon, Carl, Michaëlsson, Erik, Heijer, Maria, Kjaer, Magnus, Russell, Muir, Han, David, Lindstedt, Eva‐Lotte, Whatling, Carl, Gan, Li‐Ming, Ericsson, Hans
Published in Clinical and translational science (01.05.2021)
Published in Clinical and translational science (01.05.2021)
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Initial Clinical Experience with AZD5718, a Novel Once Daily Oral 5‐Lipoxygenase Activating Protein Inhibitor
Ericsson, Hans, Nelander, Karin, Lagerstrom‐Fermer, Maria, Balendran, Clare, Bhat, Maria, Chialda, Ligia, Gan, Li‐Ming, Heijer, Maria, Kjaer, Magnus, Lambert, John, Lindstedt, Eva‐Lotte, Forsberg, Gun‐Britt, Whatling, Carl, Skrtic, Stanko
Published in Clinical and translational science (01.05.2018)
Published in Clinical and translational science (01.05.2018)
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Regional differences and coronary microvascular dysfunction in heart failure with preserved ejection fraction
Erhardsson, Mikael, Ljung Faxén, Ulrika, Venkateshvaran, Ashwin, Svedlund, Sara, Saraste, Antti, Lagerström Fermer, Maria, Gan, Li‐Ming, Shah, Sanjiv J., Tromp, Jasper, SP Lam, Carolyn, Lund, Lars H., Hage, Camilla
Published in ESC Heart Failure (01.12.2023)
Published in ESC Heart Failure (01.12.2023)
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Prevalence and correlates of coronary microvascular dysfunction in heart failure with preserved ejection fraction: PROMIS-HFpEF
Shah, Sanjiv J, Lam, Carolyn S P, Svedlund, Sara, Saraste, Antti, Hage, Camilla, Tan, Ru-San, Beussink-Nelson, Lauren, Fermer, Maria Lagerström, Broberg, Malin A, Gan, Li-Ming, Lund, Lars H
Published in European heart journal (01.10.2018)
Published in European heart journal (01.10.2018)
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Proteomic Evaluation of the Comorbidity-Inflammation Paradigm in Heart Failure with Preserved Ejection Fraction: Results from the PROMIS-HFpEF Study
Sanders-van Wijk, Sandra, Tromp, Jasper, Beussink-Nelson, Lauren, Hage, Camilla, Svedlund, Sara, Saraste, Antti, Swat, Stanley A, Sanchez, Cynthia, Njoroge, Joyce, Tan, Ru-San, Fermer, Maria Lagerström, Gan, Li-Ming, Lund, Lars H, Lam, Carolyn S.P, Shah, Sanjiv J
Published in Circulation (New York, N.Y.) (24.11.2020)
Published in Circulation (New York, N.Y.) (24.11.2020)
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Sex differences in proteomic correlates of coronary microvascular dysfunction among patients with heart failure and preserved ejection fraction
Chandramouli, Chanchal, Ting, Tay W., Tromp, Jasper, Agarwal, Anubha, Svedlund, Sara, Saraste, Antti, Hage, Camilla, Tan, Ru‐San, Beussink‐Nelson, Lauren, Lagerström Fermer, Maria, Gan, Li‐Ming, Lund, Lars, Shah, Sanjiv J., Lam, Carolyn S.P.
Published in European journal of heart failure (01.04.2022)
Published in European journal of heart failure (01.04.2022)
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Generalizability of HFA-PEFF and H2FPEF Diagnostic Algorithms and Associations With Heart Failure Indices and Proteomic Biomarkers: Insights From PROMIS-HFpEF
Faxen, U.L., Venkateshvaran, Ashwin, Shah, Sanjiv J., Lam, Carolyn S.P., Svedlund, Sara, Saraste, Antti, Beussink-Nelson, Lauren, Lagerstrom Fermer, Maria, Gan, Li-Ming, Hage, Camilla, Lund, Lars H.
Published in Journal of cardiac failure (01.07.2021)
Published in Journal of cardiac failure (01.07.2021)
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Disproportionate left atrial myopathy in heart failure with preserved ejection fraction among participants of the PROMIS-HFpEF study
Patel, Ravi B., Lam, Carolyn S. P., Svedlund, Sara, Saraste, Antti, Hage, Camilla, Tan, Ru-San, Beussink-Nelson, Lauren, Tromp, Jasper, Sanchez, Cynthia, Njoroge, Joyce, Swat, Stanley A., Faxén, Ulrika Ljung, Fermer, Maria Lagerstrom, Venkateshvaran, Ashwin, Gan, Li-Ming, Lund, Lars H., Shah, Sanjiv J.
Published in Scientific reports (01.03.2021)
Published in Scientific reports (01.03.2021)
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Biomarker Correlates of Coronary Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction
Tromp, Jasper, Hage, Camilla, Ouwerkerk, Wouter, Sanders-van Wijk, Sandra, Svedlund, Sara, Saraste, Antti, Ljung Faxén, Ulrika, Lagerstrom Fermer, Maria, Gan, Li-ming, Lund, Lars H, Shah, Sanjiv J, Lam, Carolyn S.P
Published in Circulation (New York, N.Y.) (15.10.2019)
Published in Circulation (New York, N.Y.) (15.10.2019)
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Intradermal delivery of modified mRNA encoding VEGF-A in patients with type 2 diabetes
Gan, Li-Ming, Lagerström-Fermér, Maria, Carlsson, Leif G., Arfvidsson, Cecilia, Egnell, Ann-Charlotte, Rudvik, Anna, Kjaer, Magnus, Collén, Anna, Thompson, James D., Joyal, John, Chialda, Ligia, Koernicke, Thomas, Fuhr, Rainard, Chien, Kenneth R., Fritsche-Danielson, Regina
Published in Nature communications (20.02.2019)
Published in Nature communications (20.02.2019)
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4-aminobutyrate aminotransferase (ABAT): genetic and pharmacological evidence for an involvement in gastro esophageal reflux disease
Jirholt, Johan, Asling, Bengt, Hammond, Paul, Davidson, Geoffrey, Knutsson, Mikael, Walentinsson, Anna, Jensen, Jörgen M, Lehmann, Anders, Agreus, Lars, Lagerström-Fermer, Maria
Published in PloS one (28.04.2011)
Published in PloS one (28.04.2011)
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Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study
Wedrén, Sara, Lovmar, Lovisa, Humphreys, Keith, Magnusson, Cecilia, Melhus, Håkan, Syvänen, Ann-Christine, Kindmark, Andreas, Landegren, Ulf, Fermér, Maria Lagerström, Stiger, Fredrik, Persson, Ingemar, Baron, John A, Weiderpass, Elisabete
Published in BMC cancer (06.11.2008)
Published in BMC cancer (06.11.2008)
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Synthetic mRNA Encoding VEGF-A in Patients Undergoing Coronary Artery Bypass Grafting: Design of a Phase 2a Clinical Trial
Anttila, Vesa, Saraste, Antti, Knuuti, Juhani, Jaakkola, Pekka, Hedman, Marja, Svedlund, Sara, Lagerström-Fermér, Maria, Kjaer, Magnus, Jeppsson, Anders, Gan, Li-Ming
Published in Molecular therapy. Methods & clinical development (11.09.2020)
Published in Molecular therapy. Methods & clinical development (11.09.2020)
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Safety, tolerability, pharmacokinetics and effect on serum uric acid of the myeloperoxidase inhibitor AZD4831 in a randomized, placebo‐controlled, phase I study in healthy volunteers
Gan, Li‐Ming, Lagerström‐Fermér, Maria, Ericsson, Hans, Nelander, Karin, Lindstedt, Eva‐Lotte, Michaëlsson, Erik, Kjaer, Magnus, Heijer, Maria, Whatling, Carl, Fuhr, Rainard
Published in British journal of clinical pharmacology (01.04.2019)
Published in British journal of clinical pharmacology (01.04.2019)
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Phase 1 Pharmacokinetic Study of AZD5718 in Healthy Volunteers: Effects of Coadministration With Rosuvastatin, Formulation and Food on Oral Bioavailability
Ericsson, Hans, Nelander, Karin, Heijer, Maria, Kjaer, Magnus, Lindstedt, Eva‐Lotte, Albayaty, Muna, Forte, Pablo, Lagerström‐Fermér, Maria, Skrtic, Stanko
Published in Clinical pharmacology in drug development (01.04.2020)
Published in Clinical pharmacology in drug development (01.04.2020)
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Abstract 12847: The Heart Bus: A Mobile Patient-Centered Approach to Improve Early Diagnosis of Heart Failure in the Community
Svedlund, Sara, Lagerstrom Fermer, Maria, Valastro, Barbara, Ramne, Anna, Michaëlsson, Erik, Rudvik, Anna, Westberg, Karin, Hedner, Henrik, Nori, Radna, Gan, Li-ming
Published in Circulation (New York, N.Y.) (07.11.2023)
Published in Circulation (New York, N.Y.) (07.11.2023)
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Association of epicardial adipose tissue with proteomics, coronary flow reserve, cardiac structure and function, and quality of life in heart failure with preserved ejection fraction: insights from the PROMIS‐HFpEF study
Venkateshvaran, Ashwin, Faxen, Ulrika Ljung, Hage, Camilla, Michaëlsson, Erik, Svedlund, Sara, Saraste, Antti, Beussink‐Nelson, Lauren, Fermer, Maria Lagerstrom, Gan, Li‐Ming, Tromp, Jasper, Lam, Carolyn S.P., Shah, Sanjiv J., Lund, Lars H.
Published in European journal of heart failure (01.12.2022)
Published in European journal of heart failure (01.12.2022)
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PROspective evaluation of coronary FLOW reserve and molecular biomarkers in patients with established coronary artery disease the PROFLOW-trial: cross-sectional evaluation of coronary flow reserve
Haraldsson, Inger, Gan, Li-Ming, Svedlund, Sara, Torngren, Kristina, Westergren, Helena U, Redfors, Björn, Lagerström-Fermér, Maria, Angerås, Oskar, Råmunddal, Truls, Petursson, Petur, Odenstedt, Jacob, Albertsson, Per, Erlinge, David, Omerovic, Elmir
Published in Vascular health and risk management (01.01.2019)
Published in Vascular health and risk management (01.01.2019)
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Association of Coronary Microvascular Dysfunction With Heart Failure Hospitalizations and Mortality in Heart Failure With Preserved Ejection Fraction: A Follow-up in the PROMIS-HFpEF Study
Hage, Camilla, Svedlund, Sara, Saraste, Antti, Faxén, Ulrika Ljung, Benson, Lina, Fermer, Maria Lagerstrom, Gan, Li-Ming, Shah, Sanjiv J., Lam, Carolyn S.P., Lund, Lars H.
Published in Journal of cardiac failure (01.11.2020)
Published in Journal of cardiac failure (01.11.2020)
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Design and rationale of FLAVOUR: A phase IIa efficacy study of the 5-lipoxygenase activating protein antagonist AZD5718 in patients with recent myocardial infarction
Prescott, Eva, Pernow, John, Saraste, Antti, Åkerblom, Axel, Angerås, Oskar, Erlinge, David, Grove, Erik L., Hedman, Marja, Jensen, Lisette O., Svedlund, Sara, Kjaer, Magnus, Lagerström-Fermér, Maria, Gan, Li-Ming
Published in Contemporary clinical trials communications (01.09.2020)
Published in Contemporary clinical trials communications (01.09.2020)
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