Palmitoylation controls DLK localization, interactions and activity to ensure effective axonal injury signaling
Holland, Sabrina M., Collura, Kaitlin M., Ketschek, Andrea, Noma, Kentaro, Ferguson, Toby A., Jin, Yishi, Gallo, Gianluca, Thomas, Gareth M.
Published in Proceedings of the National Academy of Sciences - PNAS (19.01.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (19.01.2016)
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Rescue of Glaucomatous Neurodegeneration by Differentially Modulating Neuronal Endoplasmic Reticulum Stress Molecules
Yang, Liu, Li, Shaohua, Miao, Linqing, Huang, Haoliang, Liang, Feisi, Teng, Xiuyin, Xu, Lin, Wang, Qizhao, Xiao, Weidong, Ridder, 3rd, William H, Ferguson, Toby A, Chen, Dong Feng, Kaufman, Randal J, Hu, Yang
Published in The Journal of neuroscience (25.05.2016)
Published in The Journal of neuroscience (25.05.2016)
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Journal Article
Calpains mediate axonal cytoskeleton disintegration during Wallerian degeneration
Ma, Marek, Ferguson, Toby A, Schoch, Kathleen M, Li, Jian, Qian, Yaping, Shofer, Frances S, Saatman, Kathryn E, Neumar, Robert W
Published in Neurobiology of disease (01.08.2013)
Published in Neurobiology of disease (01.08.2013)
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Missense Mutations in the Copper Transporter Gene ATP7A Cause X-Linked Distal Hereditary Motor Neuropathy
Kennerson, Marina L., Nicholson, Garth A., Kaler, Stephen G., Kowalski, Bartosz, Mercer, Julian F.B., Tang, Jingrong, Llanos, Roxana M., Chu, Shannon, Takata, Reinaldo I., Speck-Martins, Carlos E., Baets, Jonathan, Almeida-Souza, Leonardo, Fischer, Dirk, Timmerman, Vincent, Taylor, Philip E., Scherer, Steven S., Ferguson, Toby A., Bird, Thomas D., De Jonghe, Peter, Feely, Shawna M.E., Shy, Michael E., Garbern, James Y.
Published in American journal of human genetics (12.03.2010)
Published in American journal of human genetics (12.03.2010)
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Journal Article
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
Miller, Timothy M., Cudkowicz, Merit E., Genge, Angela, Shaw, Pamela J., Sobue, Gen, Bucelli, Robert C., Chiò, Adriano, Van Damme, Philip, Ludolph, Albert C., Glass, Jonathan D., Andrews, Jinsy A., Babu, Suma, Benatar, Michael, McDermott, Christopher J., Cochrane, Thos, Chary, Sowmya, Chew, Sheena, Zhu, Han, Wu, Fan, Nestorov, Ivan, Graham, Danielle, Sun, Peng, McNeill, Manjit, Fanning, Laura, Ferguson, Toby A., Fradette, Stephanie
Published in The New England journal of medicine (22.09.2022)
Published in The New England journal of medicine (22.09.2022)
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Journal Article
Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
Miller, Timothy, Cudkowicz, Merit, Shaw, Pamela J, Andersen, Peter M, Atassi, Nazem, Bucelli, Robert C, Genge, Angela, Glass, Jonathan, Ladha, Shafeeq, Ludolph, Albert L, Maragakis, Nicholas J, McDermott, Christopher J, Pestronk, Alan, Ravits, John, Salachas, François, Trudell, Randall, Van Damme, Philip, Zinman, Lorne, Bennett, C. Frank, Lane, Roger, Sandrock, Alfred, Runz, Heiko, Graham, Danielle, Houshyar, Hani, McCampbell, Alexander, Nestorov, Ivan, Chang, Ih, McNeill, Manjit, Fanning, Laura, Fradette, Stephanie, Ferguson, Toby A
Published in The New England journal of medicine (09.07.2020)
Published in The New England journal of medicine (09.07.2020)
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Gold Coast diagnostic criteria: Implications for ALS diagnosis and clinical trial enrollment
Vucic, Steve, Ferguson, Toby A., Cummings, Catherine, Hotchkin, Michael T., Genge, Angela, Glanzman, Robert, Roet, Kasper C. D., Cudkowicz, Merit, Kiernan, Matthew C.
Published in Muscle & nerve (01.11.2021)
Published in Muscle & nerve (01.11.2021)
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Journal Article
Monitoring disease progression with plasma creatinine in amyotrophic lateral sclerosis clinical trials
van Eijk, Ruben P A, Eijkemans, Marinus J C, Ferguson, Toby A, Nikolakopoulos, Stavros, Veldink, Jan H, van den Berg, Leonard H
Published in Journal of neurology, neurosurgery and psychiatry (01.02.2018)
Published in Journal of neurology, neurosurgery and psychiatry (01.02.2018)
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Acute Effects of Riluzole and Retigabine on Axonal Excitability in Patients With Amyotrophic Lateral Sclerosis: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial
Kovalchuk, Maria O, Heuberger, Jules A A C, Sleutjes, Boudewijn T H M, Ziagkos, Dimitrios, van den Berg, Leonard H, Ferguson, Toby A, Franssen, Hessel, Groeneveld, Geert Jan
Published in Clinical pharmacology and therapeutics (01.12.2018)
Published in Clinical pharmacology and therapeutics (01.12.2018)
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Safety, tolerability, and pharmacokinetics of antisense oligonucleotide BIIB078 in adults with C9orf72-associated amyotrophic lateral sclerosis: a phase 1, randomised, double blinded, placebo-controlled, multiple ascending dose study
van den Berg, Leonard H, Rothstein, Jeffrey D, Shaw, Pamela J, Babu, Suma, Benatar, Michael, Bucelli, Robert C, Genge, Angela, Glass, Jonathan D, Hardiman, Orla, Libri, Vincenzo, Mobach, Theodore, Oskarsson, Björn, Pattee, Gary L, Ravits, John, Shaw, Christopher E, Weber, Markus, Zinman, Lorne, Jafar-nejad, Paymaan, Rigo, Frank, Lin, Luan, Ferguson, Toby A, Gotter, Anthony L, Graham, Danielle, Monine, Michael, Inra, Jennifer, Sinks, Susie, Eraly, Satish, Garafalo, Steve, Fradette, Stephanie
Published in Lancet neurology (01.09.2024)
Published in Lancet neurology (01.09.2024)
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Journal Article
Autologistic network model on binary data for disease progression study
Shin, Yei Eun, Sang, Huiyan, Liu, Dawei, Ferguson, Toby A., Song, Peter X. K.
Published in Biometrics (01.12.2019)
Published in Biometrics (01.12.2019)
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Critical design considerations for time-to-event endpoints in amyotrophic lateral sclerosis clinical trials
van Eijk, Ruben P A, Nikolakopoulos, Stavros, Roes, Kit C B, Middelkoop, Bas M, Ferguson, Toby A, Shaw, Pamela J, Leigh, P Nigel, Al-Chalabi, Ammar, Eijkemans, Marinus J C, van den Berg, Leonard H
Published in Journal of neurology, neurosurgery and psychiatry (01.12.2019)
Published in Journal of neurology, neurosurgery and psychiatry (01.12.2019)
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Journal Article
Increasing the efficiency of clinical trials in neurodegenerative disorders using group sequential trial designs
van Eijk, Ruben P.A., Nikolakopoulos, Stavros, Ferguson, Toby A., Liu, Dawei, Eijkemans, Marinus J.C., van den Berg, Leonard H.
Published in Journal of clinical epidemiology (01.06.2018)
Published in Journal of clinical epidemiology (01.06.2018)
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Journal Article
Association of a Novel ACTA1 Mutation With a Dominant Progressive Scapuloperoneal Myopathy in an Extended Family
Zukosky, Kristen, Meilleur, Katherine, Traynor, Bryan J, Dastgir, Jahannaz, Medne, Livija, Devoto, Marcella, Collins, James, Rooney, Jachinta, Zou, Yaqun, Yang, Michele L, Gibbs, J Raphael, Meier, Markus, Stetefeld, Joerg, Finkel, Richard S, Schessl, Joachim, Elman, Lauren, Felice, Kevin, Ferguson, Toby A, Ceyhan-Birsoy, Ozge, Beggs, Alan H, Tennekoon, Gihan, Johnson, Janel O, Bönnemann, Carsten G
Published in JAMA neurology (01.06.2015)
Published in JAMA neurology (01.06.2015)
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