Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need
Field, Mark C., Horn, David, Fairlamb, Alan H., Ferguson, Michael A. J., Gray, David W., Read, Kevin D., De Rycker, Manu, Torrie, Leah S., Wyatt, Paul G., Wyllie, Susan, Gilbert, Ian H.
Published in Nature reviews. Microbiology (01.04.2017)
Published in Nature reviews. Microbiology (01.04.2017)
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Generation of a bloodstream form Trypanosoma brucei double glycosyltransferase null mutant competent in receptor-mediated endocytosis of transferrin
Duncan, Samuel M, Carbajo, Carla Gilabert, Nagar, Rupa, Zhong, Qi, Breen, Conor, Ferguson, Michael A J, Tiengwe, Calvin
Published in PLoS pathogens (01.06.2024)
Published in PLoS pathogens (01.06.2024)
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Gluconeogenesis using glycerol as a substrate in bloodstream-form Trypanosoma brucei
Kovářová, Julie, Nagar, Rupa, Faria, Joana, Ferguson, Michael A J, Barrett, Michael P, Horn, David
Published in PLoS pathogens (01.12.2018)
Published in PLoS pathogens (01.12.2018)
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High-Confidence Glycosome Proteome for Procyclic Form Trypanosoma brucei by Epitope-Tag Organelle Enrichment and SILAC Proteomics
Güther, Maria Lucia S, Urbaniak, Michael D, Tavendale, Amy, Prescott, Alan, Ferguson, Michael A. J
Published in Journal of proteome research (06.06.2014)
Published in Journal of proteome research (06.06.2014)
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Parasite glycobiology: a bittersweet symphony
Rodrigues, Joao, Acosta-Serrano, Alvaro, Aebi, Markus, Ferguson, Michael A. J., Routier, Françoise H., Schiller, Irene, Soares, Simão, Spencer, Daniel, Titz, Alexander, Wilson, Iain B. H., Izquierdo, Luis
Published in PLoS pathogens (01.11.2015)
Published in PLoS pathogens (01.11.2015)
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N -myristoyltransferase inhibitors as new leads to treat sleeping sickness
Cleghorn, Laura A. T, Torrie, Leah S, Frearson, Julie A, Guther, M. Lucia S, Smid, Ondrej, Smith, Deborah F, Stojanovski, Laste, Wilkinson, Anthony J, Wyatt, Paul G, Brannigan, James A, Hui, Raymond, Brand, Stephen, Raimi, Olawale G, Brenk, Ruth, Robinson, David A, Hodgkinson, Michael, Ferguson, Michael A. J, Hallyburton, Irene, Mpamhanga, Chidochangu P, Gilbert, Ian H, McElroy, Stuart P, van Aalten, Daan M. F, Qiu, Wei, Read, Kevin D, Price, Helen P, Fairlamb, Alan H
Published in Nature (01.04.2010)
Published in Nature (01.04.2010)
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Proteomic Identification of Immunodiagnostic Antigens for Trypanosoma vivax Infections in Cattle and Generation of a Proof-of-Concept Lateral Flow Test Diagnostic Device
Fleming, Jennifer R, Sastry, Lalitha, Wall, Steven J, Sullivan, Lauren, Ferguson, Michael A J
Published in PLoS neglected tropical diseases (08.09.2016)
Published in PLoS neglected tropical diseases (08.09.2016)
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The serum proteome of nonalcoholic fatty liver disease: A multimodal approach to discovery of biomarkers of nonalcoholic steatohepatitis
Miller, Michael H, Walsh, Shaun V, Atrih, Abdel, Huang, Jeffrey T-J, Ferguson, Michael A J., Dillon, John F
Published in Journal of gastroenterology and hepatology (01.10.2014)
Published in Journal of gastroenterology and hepatology (01.10.2014)
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Proteomic selection of immunodiagnostic antigens for human African trypanosomiasis and generation of a prototype lateral flow immunodiagnostic device
Sullivan, Lauren, Wall, Steven J, Carrington, Mark, Ferguson, Michael A J
Published in PLoS neglected tropical diseases (01.02.2013)
Published in PLoS neglected tropical diseases (01.02.2013)
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The mRNA cap methyltransferase gene TbCMT1 is not essential in vitro but is a virulence factor in vivo for bloodstream form Trypanosoma brucei
Kelner, Anna, Tinti, Michele, Guther, Maria Lucia S, Foth, Bernardo J, Chappell, Lia, Berriman, Matthew, Cowling, Victoria Haigh, Ferguson, Michael A J
Published in PloS one (24.07.2018)
Published in PloS one (24.07.2018)
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Reprogramming of Trypanosoma cruzi metabolism triggered by parasite interaction with the host cell extracellular matrix
Mattos, Eliciane C, Canuto, Gisele, Manchola, Nubia C, Magalhães, Rubens D M, Crozier, Thomas W M, Lamont, Douglas J, Tavares, Marina F M, Colli, Walter, Ferguson, Michael A J, Alves, Maria Júlia M
Published in PLoS neglected tropical diseases (01.02.2019)
Published in PLoS neglected tropical diseases (01.02.2019)
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Discovery of a Novel Class of Orally Active Trypanocidal N-Myristoyltransferase Inhibitors
Brand, Stephen, Cleghorn, Laura A. T, McElroy, Stuart P, Robinson, David A, Smith, Victoria C, Hallyburton, Irene, Harrison, Justin R, Norcross, Neil R, Spinks, Daniel, Bayliss, Tracy, Norval, Suzanne, Stojanovski, Laste, Torrie, Leah S, Frearson, Julie A, Brenk, Ruth, Fairlamb, Alan H, Ferguson, Michael A. J, Read, Kevin D, Wyatt, Paul G, Gilbert, Ian H
Published in Journal of medicinal chemistry (12.01.2012)
Published in Journal of medicinal chemistry (12.01.2012)
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Integrative GWAS and co-localisation analysis suggests novel genes associated with age-related multimorbidity
West, Clare E., Karim, Mohd, Falaguera, Maria J., Speidel, Leo, Green, Charlotte J., Logie, Lisa, Schwartzentruber, Jeremy, Ochoa, David, Lord, Janet M., Ferguson, Michael A. J., Bountra, Chas, Wilkinson, Graeme F., Vaughan, Beverley, Leach, Andrew R., Dunham, Ian, Marsden, Brian D.
Published in Scientific data (25.09.2023)
Published in Scientific data (25.09.2023)
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Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design
Pizarro, Juan Carlos, Hills, Tanya, Senisterra, Guillermo, Wernimont, Amy K, Mackenzie, Claire, Norcross, Neil R, Ferguson, Michael A J, Wyatt, Paul G, Gilbert, Ian H, Hui, Raymond
Published in PLoS neglected tropical diseases (01.10.2013)
Published in PLoS neglected tropical diseases (01.10.2013)
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Computer-Aided Identification of Trypanosoma brucei Uridine Diphosphate Galactose 4′-Epimerase Inhibitors: Toward the Development of Novel Therapies for African Sleeping Sickness
Durrant, Jacob D, Urbaniak, Michael D, Ferguson, Michael A. J, McCammon, J. Andrew
Published in Journal of medicinal chemistry (08.07.2010)
Published in Journal of medicinal chemistry (08.07.2010)
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