Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues
Graves, Paul R, Aponte-Collazo, Lucas J, Fennell, Emily M. J, Graves, Adam C, Hale, Andrew E, Dicheva, Nedyalka, Herring, Laura E, Gilbert, Thomas S. K, East, Michael P, McDonald, Ian M, Lockett, Matthew R, Ashamalla, Hani, Moorman, Nathaniel J, Karanewsky, Donald S, Iwanowicz, Edwin J, Holmuhamedov, Ekhson, Graves, Lee M
Published in ACS chemical biology (17.05.2019)
Published in ACS chemical biology (17.05.2019)
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Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer
Fennell, Emily M J, Aponte-Collazo, Lucas J, Pathmasiri, Wimal, Rushing, Blake R, Barker, Natalie K, Partridge, Megan C, Li, Yuan-Yuan, White, Cody A, Greer, Yoshimi E, Herring, Laura E, Lipkowitz, Stanley, Sumner, Susan C J, Iwanowicz, Edwin J, Graves, Lee M
Published in Frontiers in pharmacology (31.03.2023)
Published in Frontiers in pharmacology (31.03.2023)
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Characterization of TR‐107, a novel chemical activator of the human mitochondrial protease ClpP
Fennell, Emily M. J., Aponte‐Collazo, Lucas J., Wynn, Joshua D., Drizyte‐Miller, Kristina, Leung, Elisa, Greer, Yoshimi Endo, Graves, Paul R., Iwanowicz, Andrew A., Ashamalla, Hani, Holmuhamedov, Ekhson, Lang, Henk, Karanewsky, Donald S., Der, Channing J., Houry, Walid A., Lipkowitz, Stanley, Iwanowicz, Edwin J., Graves, Lee M.
Published in Pharmacology research & perspectives (01.08.2022)
Published in Pharmacology research & perspectives (01.08.2022)
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Correction to “Mitochondrial Protease ClpP Is a Target for the Anticancer Compounds ONC201 and Related Analogues”
Graves, Paul R., Aponte-Collazo, Lucas J., Fennell, Emily M. J., Graves, Adam C., Hale, Andrew E., Dicheva, Nedyalka, Herring, Laura E., Gilbert, Thomas S. K., East, Michael P., McDonald, Ian M., Lockett, Matthew R., Ashamalla, Hani, Moorman, Nathaniel J., Karanewsky, Donald S., Iwanowicz, Edwin J., Holmuhamedov, Ekhson, Graves, Lee M.
Published in ACS chemical biology (19.08.2022)
Published in ACS chemical biology (19.08.2022)
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Mitochondrial Matrix Protease ClpP Agonists Inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis
Greer, Yoshimi Endo, Hernandez, Lidia, Fennell, Emily M J, Kundu, Manjari, Voeller, Donna, Chari, Raj, Gilbert, Samuel F, Gilbert, Thomas S K, Ratnayake, Shashikala, Tang, Binwu, Hafner, Markus, Chen, Qingrong, Meerzaman, Daoud, Iwanowicz, Edwin, Annunziata, Christina M, Graves, Lee M, Lipkowitz, Stanley
Published in Cancer research communications (10.10.2022)
Published in Cancer research communications (10.10.2022)
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Combining the constitutive TRAIL-secreting induced neural stem cell therapy with the novel anti-cancer drug TR-107 in glioblastoma
Thang, Morrent, Mellows, Clara, Kass, Lauren E., Daglish, Sabrina, Fennell, Emily M.J., Mann, Breanna E., Mercer-Smith, Alison R., Valdivia, Alain, Graves, Lee M., Hingtgen, Shawn D.
Published in Molecular Therapy Oncology (19.09.2024)
Published in Molecular Therapy Oncology (19.09.2024)
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