Brainstem development requires galactosylceramidase and is critical for pathogenesis in a model of Krabbe disease
Weinstock, Nadav I., Kreher, Conlan, Favret, Jacob, Nguyen, Duc, Bongarzone, Ernesto R., Wrabetz, Lawrence, Feltri, M. Laura, Shin, Daesung
Published in Nature communications (23.10.2020)
Published in Nature communications (23.10.2020)
Get full text
Journal Article
How Schwann Cells Sort Axons: New Concepts
Feltri, M Laura, Poitelon, Yannick, Previtali, Stefano Carlo
Published in The Neuroscientist (Baltimore, Md.) (01.06.2016)
Published in The Neuroscientist (Baltimore, Md.) (01.06.2016)
Get more information
Journal Article
Neuron-specific ablation of the Krabbe disease gene galactosylceramidase in mice results in neurodegeneration
Kreher, Conlan, Favret, Jacob, Weinstock, Nadav I, Maulik, Malabika, Hong, Xinying, Gelb, Michael H, Wrabetz, Lawrence, Feltri, M Laura, Shin, Daesung
Published in PLoS biology (05.07.2022)
Published in PLoS biology (05.07.2022)
Get full text
Journal Article
The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211
Petersen, Sarah C., Luo, Rong, Liebscher, Ines, Giera, Stefanie, Jeong, Sung-Jin, Mogha, Amit, Ghidinelli, Monica, Feltri, M. Laura, Schöneberg, Torsten, Piao, Xianhua, Monk, Kelly R.
Published in Neuron (Cambridge, Mass.) (18.02.2015)
Published in Neuron (Cambridge, Mass.) (18.02.2015)
Get full text
Journal Article
Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice
D'Antonio, Maurizio, Musner, Nicolò, Scapin, Cristina, Ungaro, Daniela, Del Carro, Ubaldo, Ron, David, Feltri, M Laura, Wrabetz, Lawrence
Published in The Journal of experimental medicine (08.04.2013)
Published in The Journal of experimental medicine (08.04.2013)
Get full text
Journal Article
Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells
Della-Flora Nunes, Gustavo, Wilson, Emma R., Marziali, Leandro N., Hurley, Edward, Silvestri, Nicholas, He, Bin, O’Malley, Bert W., Beirowski, Bogdan, Poitelon, Yannick, Wrabetz, Lawrence, Feltri, M. Laura
Published in Nature communications (02.06.2021)
Published in Nature communications (02.06.2021)
Get full text
Journal Article
Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination
Della-Flora Nunes, Gustavo, Wilson, Emma R, Hurley, Edward, He, Bin, O'Malley, Bert W, Poitelon, Yannick, Wrabetz, Lawrence, Feltri, M Laura
Published in eLife (14.09.2021)
Published in eLife (14.09.2021)
Get full text
Journal Article
Age-related neurodegeneration and cognitive impairments of NRMT1 knockout mice are preceded by misregulation of RB and abnormal neural stem cell development
Catlin, James P., Marziali, Leandro N., Rein, Benjamin, Yan, Zhen, Feltri, M. Laura, Schaner Tooley, Christine E.
Published in Cell death & disease (28.10.2021)
Published in Cell death & disease (28.10.2021)
Get full text
Journal Article
A nonsense mutation in myelin protein zero causes congenital hypomyelination neuropathy through altered P0 membrane targeting and gain of abnormal function
Fratta, Pietro, Ornaghi, Francesca, Dati, Gabriele, Zambroni, Desirée, Saveri, Paola, Belin, Sophie, D'Adamo, Patrizia, Shy, Michael, Quattrini, Angelo, Laura Feltri, M, Wrabetz, Lawrence
Published in Human molecular genetics (01.01.2019)
Published in Human molecular genetics (01.01.2019)
Get full text
Journal Article
Loss of prohibitin 2 in Schwann cells dysregulates key transcription factors controlling developmental myelination
Wilson, Emma R., Nunes, Gustavo Della‐Flora, Shen, Shichen, Moore, Seth, Gawron, Joseph, Maxwell, Jessica, Syed, Umair, Hurley, Edward, Lanka, Meghana, Qu, Jun, Désaubry, Laurent, Wrabetz, Lawrence, Poitelon, Yannick, Feltri, M. Laura
Published in Glia (01.12.2024)
Published in Glia (01.12.2024)
Get full text
Journal Article
Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice
Patzkó, Ágnes, Bai, Yunhong, Saporta, Mario A., Katona, István, Wu, XingYao, Vizzuso, Domenica, Feltri, M. Laura, Wang, Suola, Dillon, Lisa M., Kamholz, John, Kirschner, Daniel, Sarkar, Fazlul H., Wrabetz, Lawrence, Shy, Michael E.
Published in Brain (London, England : 1878) (01.12.2012)
Published in Brain (London, England : 1878) (01.12.2012)
Get full text
Journal Article
Impairment of protein degradation and proteasome function in hereditary neuropathies
VerPlank, Jordan J. S., Lokireddy, Sudarsanareddy, Feltri, M. Laura, Goldberg, Alfred L., Wrabetz, Lawrence
Published in Glia (01.02.2018)
Published in Glia (01.02.2018)
Get full text
Journal Article
Tead1 regulates the expression of Peripheral Myelin Protein 22 during Schwann cell development
Lopez-Anido, Camila, Poitelon, Yannick, Gopinath, Chetna, Moran, John J, Ma, Ki Hwan, Law, William D, Antonellis, Anthony, Feltri, M Laura, Svaren, John
Published in Human molecular genetics (15.07.2016)
Published in Human molecular genetics (15.07.2016)
Get full text
Journal Article
Enhanced axonal neuregulin-1 type-III signaling ameliorates neurophysiology and hypomyelination in a Charcot–Marie–Tooth type 1B mouse model
Scapin, Cristina, Ferri, Cinzia, Pettinato, Emanuela, Zambroni, Desiree, Bianchi, Francesca, Del Carro, Ubaldo, Belin, Sophie, Caruso, Donatella, Mitro, Nico, Pellegatta, Marta, Taveggia, Carla, Schwab, Markus H, Nave, Klaus-Armin, Feltri, M Laura, Wrabetz, Lawrence, D’Antonio, Maurizio
Published in Human molecular genetics (15.03.2019)
Published in Human molecular genetics (15.03.2019)
Get full text
Journal Article
Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction
Weinstock, Nadav I., Shin, Daesung, Dhimal, Narayan, Hong, Xinying, Irons, Eric E., Silvestri, Nicholas J., Reed, Chelsey B., Nguyen, Duc, Sampson, Oliver, Cheng, Yung-Chih, Lau, Joseph T.Y., Bongarzone, Ernesto R., Kofler, Julia, Escolar, Maria L., Gelb, Michael H., Wrabetz, Lawrence, Feltri, M. Laura
Published in Neuron (Cambridge, Mass.) (08.07.2020)
Published in Neuron (Cambridge, Mass.) (08.07.2020)
Get full text
Journal Article
The Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease
NIEMANN, Axel, HUBER, Nina, LAURA FELTRI, M, WRABETZ, Lawrence, YOUNG, Peter, WESSIG, Carsten, TOYKA, Klaus V, SUTER, Ueli, WAGNER, Konstanze M, SOMANDIN, Christian, HORN, Michael, LEBRUN-JULIEN, Frédéric, ANGST, Brigitte, PEREIRA, Jorge A, HALFTER, Hartmut, WELZL, Hans
Published in Brain (London, England : 1878) (01.03.2014)
Published in Brain (London, England : 1878) (01.03.2014)
Get full text
Journal Article
YAP and TAZ Regulate Cc2d1b and Purβ in Schwann Cells
Sophie, Belin, Jacob, Herron, Jordan, VerPlank J S, Yungki, Park, Laura, Feltri M, Yannick, Poitelon
Published in Frontiers in molecular neuroscience (17.07.2019)
Published in Frontiers in molecular neuroscience (17.07.2019)
Get full text
Journal Article
c-Jun is a negative regulator of myelination
Parkinson, David B, Bhaskaran, Ambily, Arthur-Farraj, Peter, Noon, Luke A, Woodhoo, Ashwin, Lloyd, Alison C, Feltri, M. Laura, Wrabetz, Lawrence, Behrens, Axel, Mirsky, Rhona, Jessen, Kristján R
Published in The Journal of cell biology (19.05.2008)
Published in The Journal of cell biology (19.05.2008)
Get full text
Journal Article