Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3‑Kinase δ for the Treatment of Respiratory Disease
Down, Kenneth, Amour, Augustin, Baldwin, Ian R, Cooper, Anthony W. J, Deakin, Angela M, Felton, Leigh M, Guntrip, Stephen B, Hardy, Charlotte, Harrison, Zoë A, Jones, Katherine L, Jones, Paul, Keeling, Suzanne E, Le, Joelle, Livia, Stefano, Lucas, Fiona, Lunniss, Christopher J, Parr, Nigel J, Robinson, Ed, Rowland, Paul, Smith, Sarah, Thomas, Daniel A, Vitulli, Giovanni, Washio, Yoshiaki, Hamblin, J. Nicole
Published in Journal of medicinal chemistry (24.09.2015)
Published in Journal of medicinal chemistry (24.09.2015)
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Journal Article
CCL20 neutralization by a monoclonal antibody in healthy subjects selectively inhibits recruitment of CCR6+ cells in an experimental suction blister
Bouma, Gerben, Zamuner, Stefano, Hicks, Kirsty, Want, Andrew, Oliveira, João, Choudhury, Arpita, Brett, Sara, Robertson, Darren, Felton, Leigh, Norris, Virginia, Fernando, Disala, Herdman, Michael, Tarzi, Ruth
Published in British journal of clinical pharmacology (01.09.2017)
Published in British journal of clinical pharmacology (01.09.2017)
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Journal Article
Clinical Consequences of Hepatitis B Surface Antigen Loss in Chronic Hepatitis B Infection: A Systematic Literature Review and Meta-Analysis
Morais, Eleonora, Mason, Lauren, Dever, John, Martin, Pam, Chen, Jing Voon, Felton, Leigh, Kendrick, Stuart, Theodore, Dickens, Gillespie, Iain A.
Published in Gastro hep advances (2023)
Published in Gastro hep advances (2023)
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Journal Article
Characterisation of a K390R ITK kinase dead transgenic mouse--implications for ITK as a therapeutic target
Deakin, Angela, Duddy, Graham, Wilson, Steve, Harrison, Steve, Latcham, Judi, Fulleylove, Mick, Fung, Sylvia, Smith, Jason, Pedrick, Mike, McKevitt, Tom, Felton, Leigh, Morley, Joanne, Quint, Diana, Fattah, Dilniya, Hayes, Brian, Gough, Jade, Solari, Roberto
Published in PloS one (24.09.2014)
Published in PloS one (24.09.2014)
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Journal Article
Immune-to-brain signalling: The role of cerebral CD163-positive macrophages
Galea, Ian, Felton, Leigh M., Waters, Sara, van Rooijen, Nico, Perry, V. Hugh, Newman, Tracey A.
Published in Neuroscience letters (19.12.2008)
Published in Neuroscience letters (19.12.2008)
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Journal Article
WED-370 Bepirovirsen immune mechanism of action may potentiate infected hepatocyte killing: indirect evidence from B-together peripheral longitudinal biomarker analysis
Joshi, Shilpy, Freudenberg, Johannes, Singh, Jennifer M., Felton, Leigh, Dixon, Susan, Paff, Melanie, Theodore, Dickens, Walker, Jill
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
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Journal Article
Report of the 2005 RSPCA/UFAW Rodent Welfare Group meeting
Hawkins, Penny, Felton, Leigh M, van Loo, Pascalle, Maconochie, Mark, Wells, Dominic J, Dennison, Ngaire, Hubrecht, Robert, Jennings, Maggy
Published in Lab animal (01.10.2006)
Published in Lab animal (01.10.2006)
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Journal Article
Erratum: Report of the 2005 RSPCA/UFAW Rodent Welfare Group meeting
Hawkins, Penny, Felton, Leigh M, van Loo, Pascalle, Maconochie, Mark, Wells, Dominic J, Dennison, Ngaire, Hubrecht, Robert, Jennings, Maggy
Published in Lab animal (01.11.2006)
Published in Lab animal (01.11.2006)
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Journal Article
The sickness behaviour and CNS inflammatory mediator profile induced by systemic challenge of mice with synthetic double-stranded RNA (poly I:C)
Cunningham, Colm, Campion, Suzanne, Teeling, Jessica, Felton, Leigh, Perry, V.H
Published in Brain, behavior, and immunity (01.05.2007)
Published in Brain, behavior, and immunity (01.05.2007)
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Journal Article
Sequential Peg-IFN after bepirovirsen may reduce post-treatment relapse in chronic hepatitis B
Buti, Maria, Heo, Jeong, Tanaka, Yasuhito, Andreone, Pietro, Atsukawa, Masanori, Cabezas, Joaquín, Chak, Eric, Coffin, Carla S., Fujiwara, Kei, Gankina, Natalya, Gordon, Stuart C., Janczewska, Ewa, Komori, Atsumasa, Lampertico, Pietro, McPherson, Stuart, Morozov, Vyacheslav, Plesniak, Robert, Poulin, Sébastien, Ryan, Pablo, Sagalova, Olga, Sheng, Guoping, Voloshina, Natalya, Xie, Qing, Yim, Hyung Joon, Dixon, Susan, Paff, Melanie, Felton, Leigh, Lee, Maximilian, Greene, Thomas, Lim, Jessica, Lakshminarayanan, Divya, McGonagle, Grant, Plein, Helene, Youssef, Amir, Elston, Rob, Kendrick, Stuart, Theodore, Dickens
Published in Journal of hepatology (28.08.2024)
Published in Journal of hepatology (28.08.2024)
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Journal Article
THERAPEUTIC REGIMENS FOR TREATING PSORIATIC ARTHRITIS WITH AN ANTI-CCL20 ANTIBODY
ZAMUNER, Stefano, HERDMAN, Michael, James, TARZI, Ruth, Margaret, FELTON, Leigh, Michael
Year of Publication 08.06.2017
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Year of Publication 08.06.2017
Patent
THERAPEUTIC REGIMENS FOR TREATING PSORIATIC ARTHRITIS WITH AN ANTI-CCL20 ANTIBODY
ZAMUNER, Stefano, HERDMAN, Michael, James, TARZI, Ruth, Margaret, FELTON, Leigh, Michael
Year of Publication 20.04.2017
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Year of Publication 20.04.2017
Patent