Precision digital mapping of endogenous and induced genomic DNA breaks by INDUCE-seq
Dobbs, Felix M, van Eijk, Patrick, Fellows, Mick D, Loiacono, Luisa, Nitsch, Roberto, Reed, Simon H
Published in Nature communications (09.07.2022)
Published in Nature communications (09.07.2022)
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A cross-industry survey on photosafety evaluation of pharmaceuticals after implementation of ICH S10
Bauer, Daniel, Buckley, Lorrene A., Delafoy, Laure, Ellinger-Ziegelbauer, Heidrun, Fellows, Mick D., Gerets, Helga H.J., Howe, Jonathan, Kaijser, Gerry, Nicolette, John, Pettersen, Betty A., Schimpf, Brian
Published in Regulatory toxicology and pharmacology (01.10.2021)
Published in Regulatory toxicology and pharmacology (01.10.2021)
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Journal Article
In vivo CRISPR editing with no detectable genome-wide off-target mutations
Akcakaya, Pinar, Bobbin, Maggie L, Guo, Jimmy A, Malagon-Lopez, Jose, Clement, Kendell, Garcia, Sara P, Fellows, Mick D, Porritt, Michelle J, Firth, Mike A, Carreras, Alba, Baccega, Tania, Seeliger, Frank, Bjursell, Mikael, Tsai, Shengdar Q, Nguyen, Nhu T, Nitsch, Roberto, Mayr, Lorenz M, Pinello, Luca, Bohlooly-Y, Mohammad, Aryee, Martin J, Maresca, Marcello, Joung, J Keith
Published in Nature (London) (01.09.2018)
Published in Nature (London) (01.09.2018)
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Journal Article
Extracellular vesicles induce minimal hepatotoxicity and immunogenicity
Saleh, Amer F, Lázaro-Ibáñez, Elisa, Forsgard, Malin A-M, Shatnyeva, Olga, Osteikoetxea, Xabier, Karlsson, Fredrik, Heath, Nikki, Ingelsten, Madeleine, Rose, Jonathan, Harris, Jayne, Mairesse, Maelle, Bates, Stephanie M, Clausen, Maryam, Etal, Damla, Leonard, Emilyanne, Fellows, Mick D, Dekker, Niek, Edmunds, Nicholas
Published in Nanoscale (04.04.2019)
Published in Nanoscale (04.04.2019)
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Journal Article
International evaluation study of a highly efficient culture assay for detection of residual human pluripotent stem cells in cell therapies
Watanabe, Takeshi, Yasuda, Satoshi, Chen, Connie L, Delsing, Louise, Fellows, Mick D, Foldes, Gabor, Kusakawa, Shinji, Mouriès, Lucilia Pereira, Sato, Yoji
Published in Regenerative medicine (01.03.2023)
Published in Regenerative medicine (01.03.2023)
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Journal Article
Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure–activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-d-ribose 2′-oxidase
Landge, Sudhir, Mullick, Amrita B., Nagalapur, Kavitha, Neres, João, Subbulakshmi, Venkita, Murugan, Kannan, Ghosh, Anirban, Sadler, Claire, Fellows, Mick D., Humnabadkar, Vaishali, Mahadevaswamy, Jyothi, Vachaspati, Prakash, Sharma, Sreevalli, Kaur, Parvinder, Mallya, Meenakshi, Rudrapatna, Suresh, Awasthy, Disha, Sambandamurthy, Vasan K., Pojer, Florence, Cole, Stewart T., Balganesh, Tanjore S., Ugarkar, Bheemarao G., Balasubramanian, V., Bandodkar, Balachandra S., Panda, Manoranjan, Ramachandran, Vasanthi
Published in Bioorganic & medicinal chemistry (15.12.2015)
Published in Bioorganic & medicinal chemistry (15.12.2015)
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Journal Article
2′-O-(2-Methoxyethyl) Nucleosides Are Not Phosphorylated or Incorporated Into the Genome of Human Lymphoblastoid TK6 Cells
Saleh, Amer F, Bachman, Martin, Priestley, Catherine C, Gooderham, Nigel J, Andersson, Patrik, Henry, Scott P, Edmunds, Nicholas J, Fellows, Mick D
Published in Toxicological sciences (01.05.2018)
Published in Toxicological sciences (01.05.2018)
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Journal Article
Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity
Landge, Sudhir, Ramachandran, Vasanthi, Kumar, Anupriya, Neres, João, Murugan, Kannan, Sadler, Claire, Fellows, Mick D., Humnabadkar, Vaishali, Vachaspati, Prakash, Raichurkar, Anandkumar, Sharma, Sreevalli, Ravishankar, Sudha, Guptha, Supreeth, Sambandamurthy, Vasan K., Balganesh, Tanjore S., Ugarkar, Bheemarao G., Balasubramanian, V., Bandodkar, Balachandra S., Panda, Manoranjan
Published in ChemMedChem (04.02.2016)
Published in ChemMedChem (04.02.2016)
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Journal Article
The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing – The report of an ECVAM–EFPIA workshop
Ceridono, Mara, Tellner, Pär, Bauer, Daniel, Barroso, João, Alépée, Nathalie, Corvi, Raffaella, De Smedt, Ann, Fellows, Mick D., Gibbs, Neil K., Heisler, Eckhard, Jacobs, Abigail, Jirova, Dagmar, Jones, David, Kandárová, Helena, Kasper, Peter, Akunda, Jacqueline Kinyamu, Krul, Cyrille, Learn, Douglas, Liebsch, Manfred, Lynch, Anthony M., Muster, Wolfgang, Nakamura, Kazuichi, Nash, J. Frank, Pfannenbecker, Uwe, Phillips, Gareth, Robles, Catherine, Rogiers, Vera, Van De Water, Femke, Liminga, Ulla Wändel, Vohr, Hans-Werner, Wattrelos, Olivier, Woods, Julie, Zuang, Valérie, Kreysa, Joachim, Wilcox, Phil
Published in Regulatory toxicology and pharmacology (01.08.2012)
Published in Regulatory toxicology and pharmacology (01.08.2012)
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Journal Article
The spectral karyotype of L5178Y TK+/− mouse lymphoma cells clone 3.7.2C and factors affecting mutant frequency at the thymidine kinase (tk) locus in the microtitre mouse lymphoma assay
Fellows, Mick D., McDermott, Angela, Clare, Katie R., Doherty, Ann, Aardema, Marilyn J.
Published in Environmental and molecular mutagenesis (01.01.2014)
Published in Environmental and molecular mutagenesis (01.01.2014)
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Journal Article
New approaches to advance the use of genetic toxicology analyses for human health risk assessment
Johnson, George E., Slob, Wout, Doak, Shareen H., Fellows, Mick D., Gollapudi, Bhaskar B., Heflich, Robert H., Rees, Ben J., Soeteman-Hernández, Lya G., Verma, Jatin R., Wills, John W., Jenkins, Gareth J. S., White, Paul A.
Published in Toxicology research (Cambridge) (01.01.2015)
Published in Toxicology research (Cambridge) (01.01.2015)
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Journal Article
Investigating Mesenchymal Stem Cell Sources for VEGFA mRNA Transfection and In Vivo Protein Exposure: PUB083
Menzies, Robert I., Graneli, Cecilia, Zhou, Alex X., Hong, Xuechong, Dahlqvist, Ulrika, Vaithilingam, Vijayaganapathy, Hölttä, Mikko, Henderson, Neil, Bates, Stephanie M., Fellows, Mick D., Forslöw, Anna, Zhu, Xiang yang, Ahlström, Christine, Boianelli, Alessandro, Hicks, Ryan, Lerman, Lilach O., Hansen, Pernille B. Laerkegaard
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Journal Article
Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors
Poch, Christine M, Foo, Kylie S, De Angelis, Maria Teresa, Jennbacken, Karin, Santamaria, Gianluca, Bähr, Andrea, Wang, Qing-Dong, Reiter, Franziska, Hornaschewitz, Nadja, Zawada, Dorota, Bozoglu, Tarik, My, Ilaria, Meier, Anna, Dorn, Tatjana, Hege, Simon, Lehtinen, Miia L, Tsoi, Yat Long, Hovdal, Daniel, Hyllner, Johan, Schwarz, Sascha, Sudhop, Stefanie, Jurisch, Victoria, Sini, Marcella, Fellows, Mick D, Cummings, Matthew, Clarke, Jonathan, Baptista, Ricardo, Eroglu, Elif, Wolf, Eckhard, Klymiuk, Nikolai, Lu, Kun, Tomasi, Roland, Dendorfer, Andreas, Gaspari, Marco, Parrotta, Elvira, Cuda, Giovanni, Krane, Markus, Sinnecker, Daniel, Hoppmann, Petra, Kupatt, Christian, Fritsche-Danielson, Regina, Moretti, Alessandra, Chien, Kenneth R, Laugwitz, Karl-Ludwig
Published in Nature cell biology (01.05.2022)
Published in Nature cell biology (01.05.2022)
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Journal Article
Application of microphysiological systems for nonclinical evaluation of cell therapies
Candarlioglu, Pelin L, Del sing, Louise, Gauthier, Lauren, Lewis, Lauren, Papadopoulos, George, Freag, May, Chan, Tom S, Homan, Kimberly A, Fellows, Mick D, Pointon, Amy, Kolaja, Kyle
Published in ALTEX, alternatives to animal experimentation (22.06.2024)
Published in ALTEX, alternatives to animal experimentation (22.06.2024)
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Journal Article
In vivo CRISPR editing with no detectable genomewide off-target mutations
Akcakaya, Pinar, Bobbin, Maggie L, Guo, Jimmy A, Malagon-Lopez, Jose, Clement, Kendell, Garcia, Sara P, Fellows, Mick D, Porritt, Michelle J, Firth, Mike A, Carreras, Alba, Baccega, Tania, Seeliger, Frank, Bjursell, Mikael, Tsai, Shengdar Q, Nguyen, Nhu T, Nitsch, Roberto, Mayr, Lorenz M, Pinello, Luca, Bohlooly-Y, Mohammad, Aryee, Martin J, Maresca, Marcello, Joung, J Keith
Published in Nature (London) (20.09.2018)
Published in Nature (London) (20.09.2018)
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