Network modeling of TGFβ signaling in hepatocellular carcinoma epithelial-to-mesenchymal transition reveals joint sonic hedgehog and Wnt pathway activation
Steinway, Steven Nathaniel, Zañudo, Jorge G T, Ding, Wei, Rountree, Carl Bart, Feith, David J, Loughran, Jr, Thomas P, Albert, Reka
Published in Cancer research (Chicago, Ill.) (01.11.2014)
Published in Cancer research (Chicago, Ill.) (01.11.2014)
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miR-181a is a novel player in the STAT3-mediated survival network of TCRαβ+ CD8+ T large granular lymphocyte leukemia
Assmann, Jorn L. J. C., Leon, Leticia G., Stavast, Christiaan J., van den Bogaerdt, Sanne E., Schilperoord-Vermeulen, Joyce, Sandberg, Yorick, Bellido, Mar, Erkeland, Stefan J., Feith, David J., Loughran Jr, Thomas P., Langerak, Anton W.
Published in Leukemia (01.04.2022)
Published in Leukemia (01.04.2022)
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Genomic landscape of TCRαβ and TCRγδ T-large granular lymphocyte leukemia
Cheon, HeeJin, Xing, Jeffrey C., Moosic, Katharine B., Ung, Johnson, Chan, Vivian W., Chung, David S., Toro, Mariella F., Elghawy, Omar, Wang, John S., Hamele, Cait E., Hardison, Ross C., Olson, Thomas L., Tan, Su-Fern, Feith, David J., Ratan, Aakrosh, Loughran, Thomas P.
Published in Blood (19.05.2022)
Published in Blood (19.05.2022)
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The Drug Transporter P-Glycoprotein and Its Impact on Ceramide Metabolism-An Unconventional Ally in Cancer Treatment
Ung, Johnson, Kassai, Miki, Tan, Su-Fern, Loughran, Jr, Thomas P, Feith, David J, Cabot, Myles C
Published in International journal of molecular sciences (11.09.2024)
Published in International journal of molecular sciences (11.09.2024)
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Journal Article
Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation
Tan, Su-Fern, Dunton, Wendy, Liu, Xin, Fox, Todd E., Morad, Samy A.F., Desai, Dhimant, Doi, Kenichiro, Conaway, Mark R., Amin, Shantu, Claxton, David F., Wang, Hong-Gang, Kester, Mark, Cabot, Myles C., Feith, David J., Loughran, Thomas P.
Published in Journal of lipid research (01.06.2019)
Published in Journal of lipid research (01.06.2019)
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A fluorogenic substrate for the detection of lipid amidases in intact cells
Casasampere, Mireia, Ung, Johnson, Iñáñez, Alejandro, Dufau, Carine, Tsuboi, Kazuhito, Casas, Josefina, Tan, Su-Fern, Feith, David J., Andrieu-Abadie, Nathalie, Segui, Bruno, Loughran, Thomas P., Abad, José Luis, Fabrias, Gemma
Published in Journal of lipid research (01.03.2024)
Published in Journal of lipid research (01.03.2024)
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Frequent somatic TET2 mutations in chronic NK-LGL leukemia with distinct patterns of cytopenias
Olson, Thomas L., Cheon, HeeJin, Xing, Jeffrey C., Olson, Kristine C., Paila, Umadevi, Hamele, Cait E., Neelamraju, Yaseswini, Shemo, Bryna C., Schmachtenberg, Matt, Sundararaman, Shriram K., Toro, Mariella F., Keller, Cheryl A., Farber, Emily A., Onengut-Gumuscu, Suna, Garrett-Bakelman, Francine E., Hardison, Ross C., Feith, David J., Ratan, Aakrosh, Loughran, Thomas P.
Published in Blood (26.08.2021)
Published in Blood (26.08.2021)
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IL-2 and IL-15 blockade by BNZ-1, an inhibitor of selective γ-chain cytokines, decreases leukemic T-cell viability
Wang, T. Tiffany, Yang, Jun, Zhang, Yong, Zhang, Meili, Dubois, Sigrid, Conlon, Kevin C., Tagaya, Yutaka, Hamele, Cait E., Dighe, Shubha, Olson, Thomas L., Feith, David J., Azimi, Nazli, Waldmann, Thomas A., Loughran, Thomas P.
Published in Leukemia (01.05.2019)
Published in Leukemia (01.05.2019)
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Retroviral sero‐reactivity in LGL leukaemia patients and family members
Nyland, Susan B., Feith, David J., Poss, Mary, Olson, Thomas L., Krissinger, Daniel J., Poiesz, Bernard J., Ruscetti, Francis W., Loughran, Thomas P.
Published in British journal of haematology (01.02.2020)
Published in British journal of haematology (01.02.2020)
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Vitamin D in hematological disorders and malignancies
Kulling, Paige M., Olson, Kristine C., Olson, Thomas L., Feith, David J., Loughran, Thomas P.
Published in European journal of haematology (01.03.2017)
Published in European journal of haematology (01.03.2017)
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Sphingosine kinase‐2 is overexpressed in large granular lymphocyte leukaemia and promotes survival through Mcl‐1
LeBlanc, Francis R., Pearson, Jennifer M., Tan, Su‐Fern, Cheon, HeeJin, Xing, Jeffrey C., Dunton, Wendy, Feith, David J., Loughran, Thomas P.
Published in British journal of haematology (01.08.2020)
Published in British journal of haematology (01.08.2020)
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The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia
Annageldiyev, Charyguly, Gowda, Krishne, Patel, Trupti, Bhattacharya, Priyanjali, Tan, Su-Fern, Iyer, Soumya, Desai, Dhimant, Dovat, Sinisa, Feith, David J, Loughran, Jr, Thomas P, Amin, Shantu, Claxton, David, Sharma, Arati
Published in Haematologica (Roma) (01.03.2020)
Published in Haematologica (Roma) (01.03.2020)
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TRAIL mediates and sustains constitutive NF-κB activation in LGL leukemia
Yang, Jun, LeBlanc, Francis R., Dighe, Shubha A., Hamele, Cait E., Olson, Thomas L., Feith, David J., Loughran, Thomas P.
Published in Blood (21.06.2018)
Published in Blood (21.06.2018)
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Ceramide Analogue SACLAC Modulates Sphingolipid Levels and MCL-1 Splicing to Induce Apoptosis in Acute Myeloid Leukemia
Pearson, Jennifer M, Tan, Su-Fern, Sharma, Arati, Annageldiyev, Charyguly, Fox, Todd E, Abad, Jose Luis, Fabrias, Gemma, Desai, Dhimant, Amin, Shantu, Wang, Hong-Gang, Cabot, Myles C, Claxton, David F, Kester, Mark, Feith, David J, Loughran, Thomas P
Published in Molecular cancer research (01.03.2020)
Published in Molecular cancer research (01.03.2020)
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Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells
Kao, Li-Pin, Morad, Samy A.F., Davis, Traci S., MacDougall, Matthew R., Kassai, Miki, Abdelmageed, Noha, Fox, Todd E., Kester, Mark, Loughran, Thomas P., Abad, Jose' L., Fabrias, Gemma, Tan, Su-Fern, Feith, David J., Claxton, David F., Spiegel, Sarah, Fisher-Wellman, Kelsey H., Cabot, Myles C.
Published in Journal of lipid research (01.09.2019)
Published in Journal of lipid research (01.09.2019)
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Activating STAT3 mutations in CD8+ T-cells correlate to serological positivity in rheumatoid arthritis
Moosic, Katharine B., Olson, Thomas L., Freijat, Mark, Khalique, Samara, Hamele, Cait E., Shemo, Bryna, Boodoo, Jesse, Baker, William, Khurana, Gitanjali, Schmachtenberg, Matthew, Duffy, Tristin, Ratan, Aakrosh, Darrah, Erika, Andrade, Felipe, Jones, Marieke, Olson, Kristine C., Feith, David J., Kimpel, Donald L., Loughran, Thomas P.
Published in Frontiers in immunology (21.10.2024)
Published in Frontiers in immunology (21.10.2024)
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CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk
Baer, Constance, Kimura, Shunsuke, Rana, Mitra S., Kleist, Andrew B., Flerlage, Tim, Feith, David J., Chockley, Peter, Walter, Wencke, Meggendorfer, Manja, Olson, Thomas L., Cheon, HeeJin, Olson, Kristine C., Ratan, Aakrosh, Mueller, Martha-Lena, Foran, James M., Janke, Laura J., Qu, Chunxu, Porter, Shaina N., Pruett-Miller, Shondra M., Kalathur, Ravi C., Haferlach, Claudia, Kern, Wolfgang, Paietta, Elisabeth, Thomas, Paul G., Babu, M. Madan, Loughran, Thomas P., Iacobucci, Ilaria, Haferlach, Torsten, Mullighan, Charles G.
Published in Nature genetics (01.05.2022)
Published in Nature genetics (01.05.2022)
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