MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets
Qiu, Xintao, Boufaied, Nadia, Hallal, Tarek, Feit, Avery, de Polo, Anna, Luoma, Adrienne M., Alahmadi, Walaa, Larocque, Janie, Zadra, Giorgia, Xie, Yingtian, Gu, Shengqing, Tang, Qin, Zhang, Yi, Syamala, Sudeepa, Seo, Ji-Heui, Bell, Connor, O’Connor, Edward, Liu, Yang, Schaeffer, Edward M., Jeffrey Karnes, R., Weinmann, Sheila, Davicioni, Elai, Morrissey, Colm, Cejas, Paloma, Ellis, Leigh, Loda, Massimo, Wucherpfennig, Kai W., Pomerantz, Mark M., Spratt, Daniel E., Corey, Eva, Freedman, Matthew L., Shirley Liu, X., Brown, Myles, Long, Henry W., Labbé, David P.
Published in Nature communications (13.05.2022)
Published in Nature communications (13.05.2022)
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Journal Article
Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition
Fassl, Anne, Brain, Christopher, Abu-Remaileh, Monther, Stukan, Iga, Butter, Deborah, Stepien, Piotr, Feit, Avery S, Bergholz, Johann, Michowski, Wojciech, Otto, Tobias, Sheng, Qing, Loo, Alice, Michael, Walter, Tiedt, Ralph, DeAngelis, Carmine, Schiff, Rachel, Jiang, Baishan, Jovanovic, Bojana, Nowak, Karolina, Ericsson, Maria, Cameron, Michael, Gray, Nathanael, Dillon, Deborah, Zhao, Jean J, Sabatini, David M, Jeselsohn, Rinath, Brown, Myles, Polyak, Kornelia, Sicinski, Piotr
Published in Science advances (01.06.2020)
Published in Science advances (01.06.2020)
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CoBRA: Containerized Bioinformatics Workflow for Reproducible ChIP/ATAC-seq Analysis
Qiu, Xintao, Feit, Avery S., Feiglin, Ariel, Xie, Yingtian, Kesten, Nikolas, Taing, Len, Perkins, Joseph, Gu, Shengqing, Li, Yihao, Cejas, Paloma, Zhou, Ningxuan, Jeselsohn, Rinath, Brown, Myles, Shirley Liu, X., Long, Henry W.
Published in Genomics, proteomics & bioinformatics (01.08.2021)
Published in Genomics, proteomics & bioinformatics (01.08.2021)
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Long-term clinical outcomes and healthcare utilization of sickle cell disease patients with COVID-19: A 2.5-year follow-up study
Feit, Avery, Gordon, Moshe, Alamuri, Tharun T, Hou, Wei, Mitchell, William B, Manwani, Deepa, Duong, Tim Q
Published in European journal of haematology (01.10.2023)
Published in European journal of haematology (01.10.2023)
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Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress
Liao, Yiji, Chen, Chen-Hao, Xiao, Tengfei, de la Peña Avalos, Bárbara, Dray, Eloise V, Cai, Changmeng, Gao, Shuai, Shah, Neel, Zhang, Zhao, Feit, Avery, Xue, Pengya, Liu, Zhijie, Yang, Mei, Lee, Ji Hoon, Xu, Han, Li, Wei, Mei, Shenglin, Pierre, Roodolph S, Shu, Shaokun, Fei, Teng, Duarte, Melissa, Zhao, Jin, Bradner, James E, Polyak, Kornelia, Kantoff, Philip W, Long, Henry, Balk, Steven P, Liu, X Shirley, Brown, Myles, Xu, Kexin
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2022)
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Combination of fulvestrant and chemotherapy in ESR1 Y537S mutant breast cancer cells and potential synergy mechanism related to p53 wildtype
Ma, Wen, Hermida-Prado, Francisco, Guarducci, Cristina, Feit, Avery, Nardone, Agostina, Cohen, Gabriella, Pan, Wenting, Wei, Hongliang, Li, Nanlin, Brown, Myles, Jeseslsohn, Rinath
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer
Guarducci, Cristina, Nardone, Agostina, Russo, Douglas, Nagy, Zsuzsanna, Heraud, Capucine, Grinshpun, Albert, Zhang, Qi, Freelander, Allegra, Leventhal, Mathew Joseph, Feit, Avery, Cohen Feit, Gabriella, Feiglin, Ariel, Liu, Weihan, Hermida-Prado, Francisco, Kesten, Nikolas, Ma, Wen, De Angelis, Carmine, Morlando, Antonio, O'Donnell, Madison, Naumenko, Sergey, Huang, Shixia, Nguyen, Quang-Dé, Huang, Ying, Malorni, Luca, Bergholz, Johann S, Zhao, Jean J, Fraenkel, Ernest, Lim, Elgene, Schiff, Rachel, Shapiro, Geoffrey I, Jeselsohn, Rinath
Published in Clinical cancer research (01.05.2024)
Published in Clinical cancer research (01.05.2024)
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A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer
Nardone, Agostina, Qiu, Xintao, Spisak, Sandor, Nagy, Zsuzsanna, Feiglin, Ariel, Feit, Avery, Cohen Feit, Gabriela, Xie, Yingtian, Font-Tello, Alba, Guarducci, Cristina, Hermida-Prado, Francisco, Syamala, Sudeepa, Lim, Klothilda, Munoz Gomez, Miguel, Pun, Matthew, Cornwell, MacIntosh, Liu, Weihan, Ors, Aysegul, Mohammed, Hisham, Cejas, Paloma, Brock, Jane B, Freedman, Matthew L, Winer, Eric P, Fu, Xiaoyong, Schiff, Rachel, Long, Henry W, Metzger Filho, Otto, Jeselsohn, Rinath
Published in Cancer research (Chicago, Ill.) (17.10.2022)
Published in Cancer research (Chicago, Ill.) (17.10.2022)
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Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor-Positive Breast Cancer
Hermida-Prado, Francisco, Xie, Yingtian, Sherman, Shira, Nagy, Zsuzsanna, Russo, Douglas, Akhshi, Tara, Chu, Zhengtao, Feit, Avery, Campisi, Marco, Chen, Minyue, Nardone, Agostina, Guarducci, Cristina, Lim, Klothilda, Font-Tello, Alba, Lee, Irene, García-Pedrero, Juana, Cañadas, Israel, Agudo, Judith, Huang, Ying, Sella, Tal, Jin, Qingchun, Tayob, Nabihah, Mittendorf, Elizabeth A, Tolaney, Sara M, Qiu, Xintao, Long, Henry, Symmans, William F, Lin, Jia-Ren, Santagata, Sandro, Bedrosian, Isabelle, Yardley, Denise A, Mayer, Ingrid A, Richardson, Edward T, Oliveira, Giacomo, Wu, Catherine J, Schuster, Eugene F, Dowsett, Mitch, Welm, Alana L, Barbie, David, Metzger, Otto, Jeselsohn, Rinath
Published in Cancer research (Chicago, Ill.) (02.10.2023)
Published in Cancer research (Chicago, Ill.) (02.10.2023)
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Abstract GS2-09: Tamoxifen instigates uterine cancer development by activating PI3K signaling and supersedes PIK3CA driver mutations
Kubler, Kirsten, Nardone, Agostina, Anand, Shankara, Gorvich, Daniel, Droog, Marjolein, Hermida-Prado, Francisco, Akshi, Tara, Feit, Avery S, Cohen, Gabriella, Dackus, Gwen, Pun, Matthew, Kuang, Yanan, Cha, Justin, Miller, Mendy, Gibson, William J, Paweletz, Cloud P, Van Allen, Eliezer M, van Leeuwen, Flora E, Nederlof, Petra, Hollema, Harry, Nguyen, Quang-Dé, Mourits, Marian JE, Leshchiner, Ignaty, Stewart, Chip, Matulonis, Ursula A, Zwart, Wilbert, Maruvka, Yosef E, Getz, Gad, Jeselsohn, Rinath
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Abstract GS3-07: GS3-07 Clonal evolution and mechanisms of acquired resistance to CDK4/6 inhibitors in ER-wild type and ER-mutant breast cancer
Guarducci, Cristina, Cristea, Simona, Feit, Avery, Naumenko, Sergey, Nardone, Agostina, Ma, Wen, Russo, Douglas, Feit, Gabriella Cohen, Feiglin, Ariel, Hermida-Prado, Francisco, Sherman, Shira, Brown, Myles, Michor, Franziska, Jeselsohn, Rinath
Published in Cancer research (Chicago, Ill.) (01.03.2023)
Published in Cancer research (Chicago, Ill.) (01.03.2023)
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Journal Article
A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer
Nardone, Agostina, Qui, Xintao, Feiglin, Ariel, Fu, Xiaoyong, Spisak, Sandor, Feit, Avery, Gabriella Cohen Feit, Xie, Yingtian, Font-Tello, Alba, Guarducci, Cristina, Francisco Hermida Prado, Sudeepa Syamala, Lim, Klothilda, Pun, Matthew, Macintosh Cornwell, Liu, Weihan, Ors, Aysegul, Mohammed, Hisham, Brock, Jane Elizabeth, Freedman, Matthew L, Schiff, Rachel, Winer, Eric, Long, Henry W, Otto Metzger Filho, Jeselsohn, Rinath
Published in bioRxiv (30.03.2022)
Published in bioRxiv (30.03.2022)
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Paper
CoBRA: Containerized Bioinformatics workflow for Reproducible ChIP/ATAC-seq Analysis - from differential peak calling to pathway analysis
Qiu, Xintao, Feit, Avery S, Feiglin, Ariel, Xie, Yingtian, Kesten, Nikolas, Taing, Len, Perkins, Joseph, Zhou, Ningxuan, Gu, Shengqing, Li, Yihao, Cejas, Paloma, Jeselsohn, Rinath, Brown, Myles, X Shirley Liu, Long, Henry W
Published in bioRxiv (08.11.2020)
Published in bioRxiv (08.11.2020)
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Paper
MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets
Qiu, Xintao, Boufaied, Nadia, Hallal, Tarek, Feit, Avery, De Polo, Anna, Luoma, Adrienne M, Larocque, Janie, Zadra, Giorgia, Xie, Yingtian, Gu, Shengqing, Tang, Qin, Zhang, Yi, Sudeepa Syamala, Ji-Heui Seo, Bell, Connor, Oconnor, Edward, Liu, Yang, Schaeffer, Edward M, Karnes, R Jeffrey, Weinmann, Sheila, Davicioni, Elai, Cejas, Paloma, Ellis, Leigh, Loda, Massimo, Wucherpfennig, Kai W, Pomerantz, Mark M, Spratt, Daniel E, Corey, Eva, Freedman, Matthew L, X Shirley Liu, Brown, Myles, Long, Henry W, Labbé, David P
Published in bioRxiv (24.04.2021)
Published in bioRxiv (24.04.2021)
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Paper
A non-canonical EZH2 function sensitizes solid tumors to genotoxic stress
Liao, Yiji, Chen-Hao, Chen, Shah, Neel, Xiao, Tengfei, Feit, Avery, Yang, Mei, Cai, Changmeng, Gao, Shuai, Xue, Pengya, Liu, Zhijie, Xu, Han, Lee, Jihoon, Li, Wei, Shenglin Mei, Pierre, Roodolph S, Shaokun Shu, Teng Fei, Duarte, Melissa, Zhao, Jin, Bradner, James E, Polyak, Kornelia, Kantoff, Philip W, Long, Henry, Balk, Steven P, X Shirley Liu, Brown, Myles, Xu, Kexin
Published in bioRxiv (11.09.2020)
Published in bioRxiv (11.09.2020)
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