Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex
Garrett-Thomson, Sarah C, Massimi, Aldo, Fedorov, Elena V, Bonanno, Jeffrey B, Scandiuzzi, Lisa, Hillerich, Brandan, Seidel, Ronald D, Love, James D, Garforth, Scott J, Guha, Chandan, Almo, Steven C
Published in PloS one (04.06.2020)
Published in PloS one (04.06.2020)
Get full text
Journal Article
Structural Basis of CD160:HVEM Recognition
Liu, Weifeng, Garrett, Sarah C., Fedorov, Elena V., Ramagopal, Udupi A., Garforth, Scott J., Bonanno, Jeffrey B., Almo, Steven C.
Published in Structure (London) (06.08.2019)
Published in Structure (London) (06.08.2019)
Get full text
Journal Article
Anti–CTLA-4 therapy requires an Fc domain for efficacy
Ingram, Jessica R., Blomberg, Olga S., Rashidian, Mohammad, Ali, Lestat, Garforth, Scott, Fedorov, Elena, Fedorov, Alexander A., Bonanno, Jeffrey B., Le Gall, Camille, Crowley, Stephanie, Espinosa, Camilo, Biary, Tamara, Keliher, Edmund J., Weissleder, Ralph, Almo, Steven C., Dougan, Stephanie K., Ploegh, Hidde L., Dougan, Michael
Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2018)
Get full text
Journal Article
An essential bifunctional enzyme in Mycobacterium tuberculosis for itaconate dissimilation and leucine catabolism
Wang, Hua, Fedorov, Alexander A., Fedorov, Elena V., Hunt, Debbie M., Rodgers, Angela, Douglas, Holly L., Garza-Garcia, Acely, Bonanno, Jeffrey B., Almo, Steven C., de Carvalho, Luiz Pedro Sório
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2019)
Get full text
Journal Article
HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160
Liu, Weifeng, Chou, Ting-Fang, Garrett-Thomson, Sarah C, Seo, Goo-Young, Fedorov, Elena, Ramagopal, Udupi A, Bonanno, Jeffrey B, Wang, Qingyang, Kim, Kenneth, Garforth, Scott J, Kakugawa, Kiyokazu, Cheroutre, Hilde, Kronenberg, Mitchell, Almo, Steven C
Published in The Journal of experimental medicine (06.12.2021)
Published in The Journal of experimental medicine (06.12.2021)
Get full text
Journal Article
Substrate Distortion and the Catalytic Reaction Mechanism of 5‑Carboxyvanillate Decarboxylase
Vladimirova, Anna, Patskovsky, Yury, Fedorov, Alexander A, Bonanno, Jeffrey B, Fedorov, Elena V, Toro, Rafael, Hillerich, Brandan, Seidel, Ronald D, Richards, Nigel G. J, Almo, Steven C, Raushel, Frank M
Published in Journal of the American Chemical Society (27.01.2016)
Published in Journal of the American Chemical Society (27.01.2016)
Get full text
Journal Article
Structure, Evolutionary Conservation, and Conformational Dynamics of Homo sapiens Fascin-1, an F-actin Crosslinking Protein
Sedeh, Reza Sharifi, Fedorov, Alexander A., Fedorov, Elena V., Ono, Shoichiro, Matsumura, Fumio, Almo, Steven C., Bathe, Mark
Published in Journal of molecular biology (16.07.2010)
Published in Journal of molecular biology (16.07.2010)
Get full text
Journal Article
Structural and Mechanistic Characterization of l‑Histidinol Phosphate Phosphatase from the Polymerase and Histidinol Phosphatase Family of Proteins
Ghodge, Swapnil V, Fedorov, Alexander A, Fedorov, Elena V, Hillerich, Brandan, Seidel, Ronald, Almo, Steven C, Raushel, Frank M
Published in Biochemistry (Easton) (12.02.2013)
Published in Biochemistry (Easton) (12.02.2013)
Get full text
Journal Article
Discovery of Function in the Enolase Superfamily: d‑Mannonate and d‑Gluconate Dehydratases in the d‑Mannonate Dehydratase Subgroup
Wichelecki, Daniel J, Balthazor, Bryan M, Chau, Anthony C, Vetting, Matthew W, Fedorov, Alexander A, Fedorov, Elena V, Lukk, Tiit, Patskovsky, Yury V, Stead, Mark B, Hillerich, Brandan S, Seidel, Ronald D, Almo, Steven C, Gerlt, John A
Published in Biochemistry (Easton) (29.04.2014)
Published in Biochemistry (Easton) (29.04.2014)
Get full text
Journal Article
Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily
Lukk, Tiit, Sakai, Ayano, Kalyanaraman, Chakrapani, Brown, Shoshana D, Imker, Heidi J, Song, Ling, Fedorov, Alexander A, Fedorov, Elena V, Toro, Rafael, Hillerich, Brandan, Seidel, Ronald, Patskovsky, Yury, Vetting, Matthew W, Nair, Satish K, Babbitt, Patricia C, Almo, Steven C, Gerlt, John A, Jacobson, Matthew P
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2012)
Get full text
Journal Article
Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family
Odokonyero, Denis, Sakai, Ayano, Patskovsky, Yury, Malashkevich, Vladimir N., Fedorov, Alexander A., Bonanno, Jeffrey B., Fedorov, Elena V., Toro, Rafael, Agarwal, Rakhi, Wang, Chenxi, Ozerova, Nicole D. S., Yew, Wen Shan, Sauder, J. Michael, Swaminathan, Subramanyam, Burley, Stephen K., Almo, Steven C., Glasner, Margaret E.
Published in Proceedings of the National Academy of Sciences - PNAS (10.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (10.06.2014)
Get full text
Journal Article
Discovery of a Bacterial 5‑Methylcytosine Deaminase
Hitchcock, Daniel S, Fedorov, Alexander A, Fedorov, Elena V, Almo, Steven C, Raushel, Frank M
Published in Biochemistry (Easton) (02.12.2014)
Published in Biochemistry (Easton) (02.12.2014)
Get full text
Journal Article
Prediction and assignment of function for a divergent N -succinyl amino acid racemase
Jacobson, Matthew P, Gerlt, John A, Song, Ling, Kalyanaraman, Chakrapani, Fedorov, Alexander A, Fedorov, Elena V, Glasner, Margaret E, Brown, Shoshana, Imker, Heidi J, Babbitt, Patricia C, Almo, Steven C
Published in Nature chemical biology (01.08.2007)
Published in Nature chemical biology (01.08.2007)
Get full text
Journal Article
Mechanism of the Orotidine 5′-Monophosphate Decarboxylase-Catalyzed Reaction: Evidence for Substrate Destabilization
Chan, Kui K, Wood, B. McKay, Fedorov, Alexander A, Fedorov, Elena V, Imker, Heidi J, Amyes, Tina L, Richard, John P, Almo, Steven C, Gerlt, John A
Published in Biochemistry (Easton) (23.06.2009)
Published in Biochemistry (Easton) (23.06.2009)
Get full text
Journal Article
Evolution of Enzymatic Activities in the Enolase Superfamily: l-Fuconate Dehydratase from Xanthomonas campestris
Yew, Wen Shan, Fedorov, Alexander A., Fedorov, Elena V., Rakus, John F., Pierce, Richard W., Almo, Steven C., Gerlt, John A.
Published in Biochemistry (Easton) (12.12.2006)
Published in Biochemistry (Easton) (12.12.2006)
Get full text
Journal Article
Discovery of a Dipeptide Epimerase Enzymatic Function Guided by Homology Modeling and Virtual Screening
Kalyanaraman, Chakrapani, Imker, Heidi J., Fedorov, Alexander A., Fedorov, Elena V., Glasner, Margaret E., Babbitt, Patricia C., Almo, Steven C., Gerlt, John A., Jacobson, Matthew P.
Published in Structure (London) (12.11.2008)
Published in Structure (London) (12.11.2008)
Get full text
Journal Article
Substrate Distortion and the Catalytic Reaction Mechanism of 5-Carboxyvanillate Decarboxylase
Vladimirova, Anna, Patskovsky, Yury, Fedorov, Alexander A., Bonanno, Jeffrey B., Fedorov, Elena V., Toro, Rafael, Hillerich, Brandan, Seidel, Ronald D., Richards, Nigel G. J., Almo, Steven C., Raushel, Frank M.
Published in Journal of the American Chemical Society (27.01.2016)
Published in Journal of the American Chemical Society (27.01.2016)
Get full text
Journal Article
Mechanism of the Orotidine 5′-Monophosphate Decarboxylase-Catalyzed Reaction: Importance of Residues in the Orotate Binding Site
Iiams, Vanessa, Desai, Bijoy J, Fedorov, Alexander A, Fedorov, Elena V, Almo, Steven C, Gerlt, John A
Published in Biochemistry (Easton) (04.10.2011)
Published in Biochemistry (Easton) (04.10.2011)
Get full text
Journal Article
Three-Dimensional Structure and Catalytic Mechanism of Cytosine Deaminase
Hall, Richard S, Fedorov, Alexander A, Xu, Chengfu, Fedorov, Elena V, Almo, Steven C, Raushel, Frank M
Published in Biochemistry (Easton) (07.06.2011)
Published in Biochemistry (Easton) (07.06.2011)
Get full text
Journal Article