IL-36γ Is a Strong Inducer of IL-23 in Psoriatic Cells and Activates Angiogenesis
Bridgewood, Charlie, Fearnley, Gareth W, Berekmeri, Anna, Laws, Philip, Macleod, Tom, Ponnambalam, Sreenivasan, Stacey, Martin, Graham, Anne, Wittmann, Miriam
Published in Frontiers in immunology (26.02.2018)
Published in Frontiers in immunology (26.02.2018)
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The receptor PTPRU is a redox sensitive pseudophosphatase
Hay, Iain M., Fearnley, Gareth W., Rios, Pablo, Köhn, Maja, Sharpe, Hayley J., Deane, Janet E.
Published in Nature communications (26.06.2020)
Published in Nature communications (26.06.2020)
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The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis
Smith, Gina A, Fearnley, Gareth W, Tomlinson, Darren C, Harrison, Michael A, Ponnambalam, Sreenivasan
Published in Bioscience reports (01.10.2015)
Published in Bioscience reports (01.10.2015)
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VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8
Smith, Gina A., Fearnley, Gareth W., Abdul‐Zani, Izma, Wheatcroft, Stephen B., Tomlinson, Darren C., Harrison, Michael A., Ponnambalam, Sreenivasan
Published in Traffic (Copenhagen, Denmark) (01.01.2016)
Published in Traffic (Copenhagen, Denmark) (01.01.2016)
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Journal Article
The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion
Fearnley, Gareth W, Young, Katherine A, Edgar, James R, Antrobus, Robin, Hay, Iain M, Liang, Wei-Ching, Martinez-Martin, Nadia, Lin, WeiYu, Deane, Janet E, Sharpe, Hayley J
Published in eLife (29.03.2019)
Published in eLife (29.03.2019)
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Journal Article
VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis
Fearnley, Gareth W, Smith, Gina A, Abdul-Zani, Izma, Yuldasheva, Nadira, Mughal, Nadeem A, Homer-Vanniasinkam, Shervanthi, Kearney, Mark T, Zachary, Ian C, Tomlinson, Darren C, Harrison, Michael A, Wheatcroft, Stephen B, Ponnambalam, Sreenivasan
Published in Biology open (15.05.2016)
Published in Biology open (15.05.2016)
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In silico design and biological evaluation of a dual specificity kinase inhibitor targeting cell cycle progression and angiogenesis
Latham, Antony M, Kankanala, Jayakanth, Fearnley, Gareth W, Gage, Matthew C, Kearney, Mark T, Homer-Vanniasinkam, Shervanthi, Wheatcroft, Stephen B, Fishwick, Colin W G, Ponnambalam, Sreenivasan
Published in PloS one (13.11.2014)
Published in PloS one (13.11.2014)
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Journal Article
Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function
Fearnley, Gareth W, Abdul-Zani, Izma, Latham, Antony M, Hollstein, Monica C, Ladbury, John E, Wheatcroft, Stephen B, Odell, Adam F, Ponnambalam, Sreenivasan
Published in Biology open (2019)
Published in Biology open (2019)
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Journal Article
Receptor tyrosine kinase structure and function in health and disease
A. Karpov, Oleg, W. Fearnley, Gareth, A. Smith, Gina, Kankanala, Jayakanth, J. McPherson, Michael, C. Tomlinson, Darren, A. Harrison, Michael, Ponnambalam, Sreenivasan
Published in AIMS biophysics (01.01.2015)
Published in AIMS biophysics (01.01.2015)
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The receptor protein tyrosine phosphatase PTPRK promotes intestinal repair and catalysis-independent tumour suppression
Young, Katherine A, Wojdyla, Katarzyna, Lai, Tiffany, Mulholland, Katie E, Aldaz Casanova, Silvia, Antrobus, Robin, Andrews, Simon R, Biggins, Laura, Mahler-Araujo, Betania, Barton, Philippa R, Anderson, Keith R, Fearnley, Gareth W, Sharpe, Hayley J
Published in Journal of cell science (15.07.2024)
Published in Journal of cell science (15.07.2024)
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ATF-2 and Tpl2 regulation of endothelial cell cycle progression and apoptosis
Fearnley, Gareth W., Latham, Antony M., Hollstein, Monica, Odell, Adam F., Ponnambalam, Sreenivasan
Published in Cellular signalling (01.02.2020)
Published in Cellular signalling (01.02.2020)
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Monitoring VEGF-Stimulated Calcium Ion Flux in Endothelial Cells
Critchley, William R, Fearnley, Gareth W F, Abdul-Zani, Izma, Molina-Paris, Carmen, Bendtsen, Claus, Zachary, Ian C, Harrison, Michael A, Ponnambalam, Sreenivasan
Published in Methods in molecular biology (Clifton, N.J.) (2022)
Published in Methods in molecular biology (Clifton, N.J.) (2022)
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Vascular endothelial growth factors: multitasking functionality in metabolism, health and disease
Smith, Gina A., Fearnley, Gareth W., Harrison, Michael A., Tomlinson, Darren C., Wheatcroft, Stephen B., Ponnambalam, Sreenivasan
Published in Journal of inherited metabolic disease (01.07.2015)
Published in Journal of inherited metabolic disease (01.07.2015)
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VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions
Fearnley, Gareth W, Odell, Adam F, Latham, Antony M, Mughal, Nadeem A, Bruns, Alexander F, Burgoyne, Nicholas J, Homer-Vanniasinkam, Shervanthi, Zachary, Ian C, Hollstein, Monica C, Wheatcroft, Stephen B, Ponnambalam, Sreenivasan
Published in Molecular biology of the cell (15.08.2014)
Published in Molecular biology of the cell (15.08.2014)
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Journal Article
Vascular endothelial growth factor A-stimulated signaling from endosomes in primary endothelial cells
Fearnley, Gareth W, Smith, Gina A, Odell, Adam F, Latham, Antony M, Wheatcroft, Stephen B, Harrison, Michael A, Tomlinson, Darren C, Ponnambalam, Sreenivasan
Published in Methods in enzymology (2014)
Published in Methods in enzymology (2014)
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In Silico Design and Biological Evaluation of a Dual Specificity Kinase Inhibitor Targeting Cell Cycle Progression and Angiogenesis: e110997
Latham, Antony M, Kankanala, Jayakanth, Fearnley, Gareth W, Gage, Matthew C, Kearney, Mark T, Homer-Vanniasinkam, Shervanthi, Wheatcroft, Stephen B, Fishwick, Colin WG, Ponnambalam, Sreenivasan
Published in PloS one (01.11.2014)
Published in PloS one (01.11.2014)
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Scientific Hypothesis Generation by a Large Language Model: Laboratory Validation in Breast Cancer Treatment
Abdel-Rehim, Abbi, Zenil, Hector, Orhobor, Oghenejokpeme, Fisher, Marie, Collins, Ross J, Bourne, Elizabeth, Fearnley, Gareth W, Tate, Emma, Smith, Holly X, Soldatova, Larisa N, King, Ross D
Year of Publication 20.05.2024
Year of Publication 20.05.2024
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