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1859-LB: PG-102, a Novel Bispecific GLP-1R/GLP-2R Fc-Fused Agonist—Data on Safety, Tolerability, and Pharmacokinetics (PK) in Single Ascending Dose Trial in Healthy Subjects and Preliminary Population PK Modeling
HAN, SEUNGHOON, HAN, SUNGPIL, SON, KYOUNG-HWA, SUNG, YOUNGCHUL
Published in Diabetes (New York, N.Y.) (14.06.2024)
Published in Diabetes (New York, N.Y.) (14.06.2024)
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Long‐term safety and sustained efficacy for up to 5 years of treatment with recombinant factor IX Fc fusion protein in subjects with haemophilia B: Results from the B‐YOND extension study
Pasi, K. John, Fischer, Kathelijn, Ragni, Margaret, Kulkarni, Roshni, Ozelo, Margareth C., Mahlangu, Johnny, Shapiro, Amy, P’Ng, Stephanie, Chambost, Hervé, Nolan, Beatrice, Bennett, Carolyn, Matsushita, Tadashi, Winding, Bent, Fruebis, Joachim, Yuan, Huixing, Rudin, Dan, Oldenburg, Johannes
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2020)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2020)
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Improved joint health in subjects with severe haemophilia A treated prophylactically with recombinant factor VIII Fc fusion protein
Oldenburg, J., Kulkarni, R., Srivastava, A., Mahlangu, J. N., Blanchette, V. S., Tsao, E., Winding, B., Dumont, J., Jain, N.
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2018)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2018)
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Pharmacokinetic parameters of recombinant factor IX Fc fusion protein are not influenced by factor IX antigen levels in subjects from the Phase 3 B‐LONG trial
Sidonio, Robert F., Casiano, Sandra, Falk, Aletta, Altincatal, Arman, Katragadda, Suresh, Santagostino, Elena, Windyga, Jerzy
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2023)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.01.2023)
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Recombinant factor VIII Fc fusion protein for the treatment of severe haemophilia A: Final results from the ASPIRE extension study
Nolan, Beatrice, Mahlangu, Johnny, Pabinger, Ingrid, Young, Guy, Konkle, Barbara A., Barnes, Chris, Nogami, Keiji, Santagostino, Elena, Pasi, K. John, Khoo, Liane, Winding, Bent, Yuan, Huixing, Fruebis, Joachim, Rudin, Dan, Oldenburg, Johannes
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2020)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.05.2020)
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First-in-Human Study on Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Escalating Doses of HEC88473, a Novel Dual GLP-1 and FGF21 Receptor Agonist in Healthy and Obese Chinese Subjects
Zhang, Hong, Li, Qianqian, Chen, Hong, Guo, Lingfeng, Li, Jing, Xie, Can, Yan, Jiangyu, Ding, Yanhua
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01.05.2025)
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01.05.2025)
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Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE
Galeotti, Caroline, Stephen-Victor, Emmanuel, Karnam, Anupama, Das, Mrinmoy, Gilardin, Laurent, Maddur, Mohan S., Wymann, Sandra, Vonarburg, Cédric, Chevailler, Alain, Dimitrov, Jordan D., Benveniste, Olivier, Bruhns, Pierre, Kaveri, Srini V., Bayry, Jagadeesh
Published in Journal of allergy and clinical immunology (01.08.2019)
Published in Journal of allergy and clinical immunology (01.08.2019)
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Tolerance of Centrifuge-Simulated Commercial Spaceflight in a Subject with Hemophilia A
Reeves, Isaiah A, Blue, Rebecca S, Auñon-Chancellor, Serena, Harrison, Michael F, Shah, Ronak, Powers, William E
Published in Aerospace medicine and human performance (01.06.2023)
Published in Aerospace medicine and human performance (01.06.2023)
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The Immunosuppressive Receptor CD32b Regulation of Macrophage Polarization and Its Implications in Tumor Progression
Chuang, Hong-Jing, Chen, Ying-Yin, Chung, Yi-Da, Huang, Evelyn, Huang, Cadence Yoshang, Lung, Jrhau, Chen, Chung-Yu, Liao, Hui-Fen
Published in International journal of molecular sciences (01.09.2024)
Published in International journal of molecular sciences (01.09.2024)
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Spatial requirements for ITAM signaling in an intracellular natural killer cell model membrane
Chong, Gene, MacKerell, Alexander D.
Published in Biochimica et biophysica acta. General subjects (01.11.2022)
Published in Biochimica et biophysica acta. General subjects (01.11.2022)
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Population Pharmacokinetic Analysis of Recombinant Factor VIII Fc Fusion Protein in Subjects With Severe Hemophilia A: Expanded to Include Pediatric Subjects
Katragadda, Suresh, Neelakantan, Srividya, Diao, Lei, Wong, Nancy
Published in Journal of clinical pharmacology (01.07.2021)
Published in Journal of clinical pharmacology (01.07.2021)
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In Vitro Glycoengineering of IgG1 and Its Effect on Fc Receptor Binding and ADCC Activity
Thomann, Marco, Schlothauer, Tilman, Dashivets, Tetyana, Malik, Sebastian, Avenal, Cecile, Bulau, Patrick, Rüger, Petra, Reusch, Dietmar
Published in PloS one (12.08.2015)
Published in PloS one (12.08.2015)
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Michael M. Frank: February 28, 1937–August 1, 2019
O’Shea, John J., Gallin, John I., Atkinson, John P., Lawley, Thomas, Metcalf, Dean D., Strober, Warren, Buckley, Rebecca H., Fauci, Anthony S.
Published in Journal of allergy and clinical immunology (01.12.2019)
Published in Journal of allergy and clinical immunology (01.12.2019)
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Guideline for the management of myasthenic syndromes
Wiendl, Heinz, Abicht, Angela, Chan, Andrew, Della Marina, Adela, Hagenacker, Tim, Hekmat, Khosro, Hoffmann, Sarah, Hoffmann, Hans-Stefan, Jander, Sebastian, Keller, Christian, Marx, Alexander, Melms, Arthur, Melzer, Nico, Müller-Felber, Wolfgang, Pawlitzki, Marc, Rückert, Jens-Carsten, Schara-Schmidt, Ulrike, Schneider-Gold, Christiane, Schoser, Benedikt, Schreiner, Bettina, Schroeter, Michael, Schubert, Bettina, Sieb, Jörn-Peter, Zimprich, Fritz, Meisel, Andreas
Published in Therapeutic advances in neurological disorders (01.01.2023)
Published in Therapeutic advances in neurological disorders (01.01.2023)
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First‐in‐human study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALPN‐101, a dual CD28/ICOS antagonist, in healthy adult subjects
Yang, Jing, Lickliter, Jason D., Hillson, Jan L., Means, Gary D., Sanderson, Russell J., Carley, Kay, Tercero, Almudena, Manjarrez, Kristi L., Wiley, Jennifer R., Peng, Stanford L.
Published in Clinical and translational science (01.07.2021)
Published in Clinical and translational science (01.07.2021)
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