Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer
Mezynski, M Janusz, Farrelly, Angela M, Cremona, Mattia, Carr, Aoife, Morgan, Clare, Workman, Julie, Armstrong, Paul, McAuley, Jennifer, Madden, Stephen, Fay, Joanna, Sheehan, Katherine M, Kay, Elaine W, Holohan, Ciara, Elamin, Yasir, Rafee, Shereen, Morris, Patrick G, Breathnach, Oscar, Grogan, Liam, Hennessy, Bryan T, Toomey, Sinead
Published in Journal of translational medicine (01.05.2021)
Published in Journal of translational medicine (01.05.2021)
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Proteomic time course of breast cancer cells highlights enhanced sensitivity to Stat3 and Src inhibitors prior to endocrine resistance development
Madden, Stephen F, Cremona, Mattia, Farrelly, Angela M, Low, Weng Hei, McBryan, Jean
Published in Cancer gene therapy (01.02.2023)
Published in Cancer gene therapy (01.02.2023)
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BRCA mutations lead to XIAP overexpression and sensitise ovarian cancer to inhibitor of apoptosis (IAP) family inhibitors
Cremona, Mattia, Vandenberg, Cassandra J, Farrelly, Angela M, Madden, Stephen F, Morgan, Clare, Kalachand, Roshni, McAlpine, Jessica N, Toomey, Sinead, Huntsman, David G, Grogan, Liam, Breathnach, Oscar, Morris, Patrick, Carey, Mark S, Scott, Clare L, Hennessy, Bryan T
Published in British journal of cancer (01.08.2022)
Published in British journal of cancer (01.08.2022)
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Combined Targeted Resequencing of Cytosine DNA Methylation and Mutations of DNA Repair Genes with Potential Use for Poly(ADP-Ribose) Polymerase 1 Inhibitor Sensitivity Testing
Grimm, Christina, Fischer, Axel, Farrelly, Angela M., Kalachand, Roshni, Castiglione, Roberta, Wasserburger, Elena, Hussong, Michelle, Schultheis, Anne M., Altmüller, Janine, Thiele, Holger, Reinhardt, H. Christian, Hauschulz, Kai, Hennessy, Bryan T., Herwig, Ralf, Lienhard, Matthias, Buettner, Reinhard, Schweiger, Michal R.
Published in The Journal of molecular diagnostics : JMD (01.03.2019)
Published in The Journal of molecular diagnostics : JMD (01.03.2019)
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AMP-activated Protein Kinase Mediates Apoptosis in Response to Bioenergetic Stress through Activation of the Pro-apoptotic Bcl-2 Homology Domain-3-only Protein BMF
Kilbride, Seán M., Farrelly, Angela M., Bonner, Caroline, Ward, Manus W., Nyhan, Kristine C., Concannon, Caoimhín G., Wollheim, Claes B., Byrne, Maria M., Prehn, Jochen H.M.
Published in The Journal of biological chemistry (12.11.2010)
Published in The Journal of biological chemistry (12.11.2010)
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INS-1 Cells Undergoing Caspase-Dependent Apoptosis Enhance the Regenerative Capacity of Neighboring Cells
BONNER, Caroline, BACON, Siobhán, WOLLHEIM, Claes B, GRAF, Rolf, BYRNE, Maria M, PREHN, Jochen H. M, CONCANNON, Caoimhín G, RIZVI, Syed R, BAQUIE, Mathurin, FARRELLY, Angela M, KILBRIDE, Seán M, DUSSMANN, Heiko, WARD, Manus W, BOULANGER, Chantal M
Published in Diabetes (New York, N.Y.) (01.11.2010)
Published in Diabetes (New York, N.Y.) (01.11.2010)
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Bone Morphogenetic Protein 3 Controls Insulin Gene Expression and Is Down-regulated in INS-1 Cells Inducibly Expressing a Hepatocyte Nuclear Factor 1A–Maturity-onset Diabetes of the Young Mutation
Bonner, Caroline, Farrelly, Angela M., Concannon, Caoimhín G., Dussmann, Heiko, Baquié, Mathurin, Virard, Isabelle, Wobser, Hella, Kögel, Donat, Wollheim, Claes B., Rupnik, Marjan, Byrne, Maria M., König, Hans-Georg, Prehn, Jochen H.M.
Published in The Journal of biological chemistry (22.07.2011)
Published in The Journal of biological chemistry (22.07.2011)
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Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells
Farrelly, Angela M., Kilbride, Seán M., Bonner, Caroline, Prehn, Jochen H. M., Byrne, Maria M.
Published in Apoptosis (London) (01.11.2011)
Published in Apoptosis (London) (01.11.2011)
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Abstract P1-19-24: A phase Ib trial of copanlisib in combination with trastuzumab in pretreated recurrent or metastatic HER2-positive breast cancer “PantHER”
Keegan, Niamh M, Furney, Simon, Walshe, Janice, Gullo, Giuseppe, Kennedy, John, Bulger, Kyran, McCaffrey, John, Kelly, Catherine M, Egan, Keith, O'Donovan, P, Hernando, Andres, Teiserskiene, Ausra, Parker, Imelda, Farrelly, Angela M, Carr, Aoife, Calzaferri, Giulio, McDermott, Ray, Keane, Maccon M, Grogan, Liam, Breathnach, Oscar S, Morris, Patrick G, Toomey, Sinead, Hennessy, Bryan T
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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