Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model
Natoni, Alessandro, Farrell, Mariah L, Harris, Sophie, Falank, Carolyne, Kirkham-McCarthy, Lucy, Macauley, Matthew S, Reagan, Michaela R, O'Dwyer, Michael
Published in Haematologica (Roma) (01.02.2020)
Published in Haematologica (Roma) (01.02.2020)
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Journal Article
Myeloma-Modified Adipocytes Exhibit Metabolic Dysfunction and a Senescence-Associated Secretory Phenotype
Fairfield, Heather, Dudakovic, Amel, Khatib, Casper M, Farrell, Mariah, Costa, Samantha, Falank, Carolyne, Hinge, Maja, Murphy, Connor S, DeMambro, Victoria, Pettitt, Jessica A, Lary, Christine W, Driscoll, Heather E, McDonald, Michelle M, Kassem, Moustapha, Rosen, Clifford, Andersen, Thomas L, van Wijnen, Andre J, Jafari, Abbas, Reagan, Michaela R
Published in Cancer research (Chicago, Ill.) (01.02.2021)
Published in Cancer research (Chicago, Ill.) (01.02.2021)
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Journal Article
Soluble and Cell-Cell-Mediated Drivers of Proteasome Inhibitor Resistance in Multiple Myeloma
Farrell, Mariah L, Reagan, Michaela R
Published in Frontiers in endocrinology (Lausanne) (01.05.2018)
Published in Frontiers in endocrinology (Lausanne) (01.05.2018)
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Journal Article
Development and characterization of three cell culture systems to investigate the relationship between primary bone marrow adipocytes and myeloma cells
Fairfield, Heather, Condruti, Rebecca, Farrell, Mariah, Di Iorio, Reagan, Gartner, Carlos A, Vary, Calvin, Reagan, Michaela R
Published in Frontiers in oncology (11.01.2023)
Published in Frontiers in oncology (11.01.2023)
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Journal Article
11. Bone marrow adipocyte-induced increases in lipid content and fatty acid binding proteins may support proliferation in myeloma cells
Fairfield, Heather, Farrell, Mariah, Krip, Kristen, Kayoyo Masengo, Patricia, Reagan, Michaela
Published in Journal of bone oncology (01.04.2024)
Published in Journal of bone oncology (01.04.2024)
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Journal Article
Multiple Myeloma Cells Alter Adipogenesis, Increase Senescence-Related and Inflammatory Gene Transcript Expression, and Alter Metabolism in Preadipocytes
Fairfield, Heather, Costa, Samantha, Falank, Carolyne, Farrell, Mariah, Murphy, Connor S, D'Amico, Anastasia, Driscoll, Heather, Reagan, Michaela R
Published in Frontiers in oncology (18.02.2021)
Published in Frontiers in oncology (18.02.2021)
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Journal Article
Targeting the fatty acid binding proteins disrupts multiple myeloma cell cycle progression and MYC signaling
Farrell, Mariah, Fairfield, Heather, Karam, Michelle, D'Amico, Anastasia, Murphy, Connor S, Falank, Carolyne, Pistofidi, Romanos Sklavenitis, Cao, Amanda, Marinac, Catherine R, Dragon, Julie A, McGuinness, Lauren, Gartner, Carlos G, Iorio, Reagan Di, Jachimowicz, Edward, DeMambro, Victoria, Vary, Calvin, Reagan, Michaela R
Published in eLife (07.03.2023)
Published in eLife (07.03.2023)
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Journal Article
Targeting Bone Marrow Adipose Tissue and the FABP Family Increases Efficacy of Dexamethasone in Multiple Myeloma
Farrell, Mariah, Fairfield, Heather, Murphy, Connor S, D'Amico, Anastasia
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Abstract 2962: Investigation of the relationship between obesity, weight cycling, and tumor progression in a murine myeloma model
Fairfield, Heather, Marinac, Catherine, Farrell, Mariah, Birmann, Brenda, Reagan, Michaela Ruth
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Investigating the Relationship between Primary Bone Marrow Adipocytes and Myeloma Cells with Three Cell Culture Systems
Fairfield, Heather, Condruti, Rebecca, Farrell, Mariah, Di Iorio, Reagan, Vary, Calvin, Gartner, Carlos A, Reagan, Michaela R
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Development of a 3D bone marrow adipose tissue model
Fairfield, Heather, Falank, Carolyne, Farrell, Mariah, Vary, Calvin, Boucher, Joshua M., Driscoll, Heather, Liaw, Lucy, Rosen, Clifford J., Reagan, Michaela R.
Published in Bone (New York, N.Y.) (01.01.2019)
Published in Bone (New York, N.Y.) (01.01.2019)
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Journal Article
New Bone Cell Type Identified As Driver of Drug Resistance in Multiple Myeloma: The Bone Marrow Adipocyte
Falank, Carolyne, Fairfield, Heather, Farrell, Mariah, Reagan, Michaela
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Sclerostin‐Neutralizing Antibody Treatment Rescues Negative Effects of Rosiglitazone on Mouse Bone Parameters
Farrell, Mariah, Fairfield, Heather, Costa, Samantha, D'Amico, Anastasia, Falank, Carolyne, Brooks, Daniel J, Reagan, Michaela R
Published in Journal of bone and mineral research (01.01.2021)
Published in Journal of bone and mineral research (01.01.2021)
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Journal Article
Acyl-CoA Synthetase Long Chain Family Inhibition with Triacsin C Inhibits Multiple Myeloma Cell Proliferation and Survival
Murphy, Connor S, Fairfield, Heather, Farrell, Mariah, DeMambro, Victoria, Costa, Samantha, Falank, Carolyne, Vary, Calvin, Reagan, Michaela
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Fatty Acid Binding Proteins As a Novel Therapeutic Target in Multiple Myeloma
Farrell, Mariah, Fairfield, Heather, D'Amico, Anastasia, Murphy, Connor S, Falank, Carolyne, Marinac, Catherine R., Romanos, Sklavenitis-Pistofidis, Cao, Amanda, Dragon, Julie, Reagan, Michaela R
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Sclerostin antibody increases trabecular bone and bone mechanical properties by increasing osteoblast activity damaged by whole-body irradiation in mice
Costa, Samantha, Fairfield, Heather, Farrell, Mariah, Murphy, Connor S., Soucy, Ashley, Vary, Calvin, Holdsworth, Gill, Reagan, Michaela R.
Published in Bone (New York, N.Y.) (01.06.2021)
Published in Bone (New York, N.Y.) (01.06.2021)
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Journal Article
Inhibition of Sialylation Impairs Adhesion on Madcam-1 and E-Selectin and Sensitize Multiple Myeloma Cells to Bortezomib in a Xenograft Mouse Model
Natoni, Alessandro, Farrell, Mariah, Fairfield, Heather, Kirkham-McCarthy, Lucy, Macauley, Matt, Reagan, Michaela, O'Dwyer, Michael E
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
Development of medical-grade, discrete, multi-walled carbon nanotubes as drug delivery molecules to enhance the treatment of hematological malignancies
Falank, Carolyne, Tasset, Aaron W., Farrell, Mariah, Harris, Sophie, Everill, Paul, Marinkovic, Milos, Reagan, Michaela R.
Published in Nanomedicine (01.08.2019)
Published in Nanomedicine (01.08.2019)
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Journal Article