Inhibition of the activation of γδT17 cells through PPARγ–PTEN/Akt/GSK3β/NFAT pathway contributes to the anti-colitis effect of madecassic acid
Yun, Xinming, Fang, Yulai, Lv, Changjun, Qiao, Simiao, Tao, Yu, Dai, Yue, Xia, Yufeng
Published in Cell death & disease (14.09.2020)
Published in Cell death & disease (14.09.2020)
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Mitochondrial fusion induced by transforming growth factor-β1 serves as a switch that governs the metabolic reprogramming during differentiation of regulatory T cells
Fang, Yulai, Zhang, Qin, Lv, Changjun, Guo, Yilei, He, Yue, Guo, Pengxiang, Wei, Zhifeng, Xia, Yufeng, Dai, Yue
Published in Redox biology (01.06.2023)
Published in Redox biology (01.06.2023)
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Qin-Yu-Qing-Chang decoction reshapes colonic metabolism by activating PPAR-γ signaling to inhibit facultative anaerobes against DSS-induced colitis
Xu, Feng, Hu, Jingyi, Li, Yanan, Cheng, Cheng, Au, Ryan, Tong, Yiheng, Wu, Yuguang, Cui, Yuan, Fang, Yulai, Chen, Hongxin, Zhu, Lei, Shen, Hong
Published in Chinese medicine (26.09.2024)
Published in Chinese medicine (26.09.2024)
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Cholinergic dysfunction-induced insufficient activation of alpha7 nicotinic acetylcholine receptor drives the development of rheumatoid arthritis through promoting protein citrullination via the SP3/PAD4 pathway
Lv, Changjun, Sun, Minghui, Guo, Yilei, Xia, Wenxin, Qiao, Simiao, Tao, Yu, Fang, Yulai, Zhang, Qin, Zhu, Yanrong, Yalikun, Yusufu, Xia, Yufeng, Wei, Zhifeng, Dai, Yue
Published in Acta pharmaceutica Sinica. B (01.04.2023)
Published in Acta pharmaceutica Sinica. B (01.04.2023)
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The gut microbiota modulator berberine ameliorates collagen-induced arthritis in rats by facilitating the generation of butyrate and adjusting the intestinal hypoxia and nitrate supply
Yue, Mengfan, Tao, Yu, Fang, Yulai, Lian, Xingpan, Zhang, Qin, Xia, Yufeng, Wei, Zhifeng, Dai, Yue
Published in The FASEB journal (01.11.2019)
Published in The FASEB journal (01.11.2019)
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AhR activation promotes Treg cell generation by enhancing Lkb1‐mediated fatty acid oxidation via the Skp2/K63‐ubiquitination pathway
Zhang, Qin, Zhu, Yanrong, Lv, Changjun, Fang, Yulai, Liao, Minhui, Xia, Yufeng, Wei, Zhifeng, Dai, Yue
Published in Immunology (01.08.2023)
Published in Immunology (01.08.2023)
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A network pharmacology approach and experimental validation to investigate the anticancer mechanism of Qi-Qin-Hu-Chang formula against colitis-associated colorectal cancer through induction of apoptosis via JNK/p38 MAPK signaling pathway
Wu, Yuguang, Fang, Yulai, Li, Yanan, Au, Ryan, Cheng, Cheng, Li, Weiyang, Xu, Feng, Cui, Yuan, Zhu, Lei, Shen, Hong
Published in Journal of ethnopharmacology (30.01.2024)
Published in Journal of ethnopharmacology (30.01.2024)
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Pharmacological activation of ERβ by arctigenin maintains the integrity of intestinal epithelial barrier in inflammatory bowel diseases
Tao, Yu, Yue, Mengfan, Lv, Changjun, Yun, Xinming, Qiao, Simiao, Fang, Yulai, Wei, Zhifeng, Xia, Yufeng, Dai, Yue
Published in The FASEB journal (01.02.2020)
Published in The FASEB journal (01.02.2020)
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Madecassic acid alleviates colitis-associated colorectal cancer by blocking the recruitment of myeloid-derived suppressor cells via the inhibition of IL-17 expression in γδT17 cells
Yun, Xinming, Zhang, Qin, Fang, Yulai, Lv, Changjun, Chen, Qingyong, Chu, Yuyao, Zhu, Yanrong, Wei, Zhifeng, Xia, Yufeng, Dai, Yue
Published in Biochemical pharmacology (01.08.2022)
Published in Biochemical pharmacology (01.08.2022)
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Tetrandrine, an immunosuppressive alkaloid isolated from Steohania tetrandra S. Moore, induces the generation of Treg cells through enhancing fatty acid oxidation
Fang, Yulai, Zhang, Qin, Yuan, Xusheng, Lv, Changjun, Zhang, Jing, Zhu, Yanrong, Wei, Zhifeng, Xia, Yufeng, Dai, Yue
Published in Immunology (01.08.2022)
Published in Immunology (01.08.2022)
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Synthesis of norisoboldine derivatives and bioactivity assay for inducing the generation of regulatory T cells
Chang, Lan, Zhang, Qin, Tang, Yunqing, Fang, Yulai, Dou, Renjie, Chu, Yuyao, Xia, Yufeng, Wei, Zhifeng, Chen, Li, Dai, Yue
Published in Bioorganic & medicinal chemistry letters (01.04.2021)
Published in Bioorganic & medicinal chemistry letters (01.04.2021)
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The neuropeptide cortistatin attenuates Th17 cell response through inhibition of glycolysis via GHSR1
Guo, Yilei, Sun, Dandan, Zhang, Yajing, Yu, Xiaoxiao, Fang, Yulai, Lv, Changjun, Zhang, Qin, Zhu, Yanrong, Qiao, Simiao, Xia, Yufeng, Wei, Zhifeng, Dai, Yue
Published in International immunopharmacology (01.07.2022)
Published in International immunopharmacology (01.07.2022)
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Qin-Yu-Qing-Chang decoction reshapes colonic metabolism by activating PPAR-[gamma] signaling to inhibit facultative anaerobes against DSS-induced colitis
Xu, Feng, Hu, Jingyi, Li, Yanan, Cheng, Cheng, Au, Ryan, Tong, Yiheng, Wu, Yuguang, Cui, Yuan, Fang, Yulai, Chen, Hongxin, Zhu, Lei, Shen, Hong
Published in Chinese medicine (26.09.2024)
Published in Chinese medicine (26.09.2024)
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Integrated Network Pharmacology, Molecular Docking and Animal Experiment to Explore the Efficacy and Potential Mechanism of Baiyu Decoction Against Ulcerative Colitis by Enema
Cui, Yuan, Hu, Jingyi, Li, Yanan, Au, Ryan, Fang, Yulai, Cheng, Cheng, Xu, Feng, Li, Weiyang, Wu, Yuguang, Zhu, Lei, Shen, Hong
Published in Drug design, development and therapy (30.11.2023)
Published in Drug design, development and therapy (30.11.2023)
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