Structure−Activity Relationships of Pyrazole Derivatives as Cannabinoid Receptor Antagonists
Lan, Ruoxi, Liu, Qian, Fan, Pusheng, Lin, Sonyuan, Fernando, Susanthi R, McCallion, Deirdre, Pertwee, Roger, Makriyannis, Alexandros
Published in Journal of medicinal chemistry (25.02.1999)
Published in Journal of medicinal chemistry (25.02.1999)
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C1‘-Cycloalkyl Side Chain Pharmacophore in Tetrahydrocannabinols
Papahatjis, Demetris P, Nahmias, Victoria R, Nikas, Spyros P, Andreou, Thanos, Alapafuja, Shakiru O, Tsotinis, Andrew, Guo, Jianxin, Fan, Pusheng, Makriyannis, Alexandros
Published in Journal of medicinal chemistry (23.08.2007)
Published in Journal of medicinal chemistry (23.08.2007)
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Adamantyl Cannabinoids: A Novel Class of Cannabinergic Ligands
Lu, Dai, Meng, Zhaoxing, Thakur, Ganesh A, Fan, Pusheng, Steed, John, Tartal, Cindy L, Hurst, Dow P, Reggio, Patricia H, Deschamps, Jeffrey R, Parrish, Damon A, George, Clifford, Järbe, Torbjörn U. C, Lamb, Richard J, Makriyannis, Alexandros
Published in Journal of medicinal chemistry (14.07.2005)
Published in Journal of medicinal chemistry (14.07.2005)
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Novel Analogues of Arachidonylethanolamide (Anandamide): Affinities for the CB1 and CB2 Cannabinoid Receptors and Metabolic Stability
Lin, Sonyuan, Khanolkar, Atmaram D, Fan, Pusheng, Goutopoulos, Andreas, Qin, Ce, Papahadjis, Demetris, Makriyannis, Alexandros
Published in Journal of medicinal chemistry (31.12.1998)
Published in Journal of medicinal chemistry (31.12.1998)
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Potent Cannabinergic Indole Analogues as Radioiodinatable Brain Imaging Agents for the CB1 Cannabinoid Receptor
Deng, Hongfeng, Gifford, Andrew N, Zvonok, Alexander M, Cui, Guangjian, Li, Xiuyan, Fan, Pusheng, Deschamps, Jeffrey R, Flippen-Anderson, Judith L, Gatley, S. John, Makriyannis, Alexandros
Published in Journal of medicinal chemistry (06.10.2005)
Published in Journal of medicinal chemistry (06.10.2005)
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Substrate Specificity and Stereoselectivity of Rat Brain Microsomal Anandamide Amidohydrolase
Lang, Wensheng, Qin, Ce, Lin, Sonyuan, Khanolkar, Atmaram D, Goutopoulos, Andreas, Fan, Pusheng, Abouzid, Khaled, Meng, Zhaoxing, Biegel, Diane, Makriyannis, Alexandros
Published in Journal of medicinal chemistry (11.03.1999)
Published in Journal of medicinal chemistry (11.03.1999)
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Structural modifications of the cannabinoid side chain towards C3-aryl and 1′,1′-cycloalkyl-1′-cyano cannabinoids
Papahatjis, Demetris P., Nahmias, Victoria R., Andreou, Thanos, Fan, Pusheng, Makriyannis, Alexandros
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
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Stereochemical Selectivity of Methanandamides for the CB1 and CB2 Cannabinoid Receptors and Their Metabolic Stability
Goutopoulos, Andreas, Fan, Pusheng, Khanolkar, Atmaram D, Xie, Xian-Qun, Lin, Sonyuan, Makriyannis, Alexandros
Published in Bioorganic & medicinal chemistry (01.07.2001)
Published in Bioorganic & medicinal chemistry (01.07.2001)
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Classical/Nonclassical Hybrid Cannabinoids: Southern Aliphatic Chain-Functionalized C-6β Methyl, Ethyl, and Propyl Analogues
Drake, David J, Jensen, Rader S, Busch-Petersen, Jakob, Kawakami, Joel K, Concepcion Fernandez-Garcia, M, Fan, Pusheng, Makriyannis, Alexandros, Tius, Marcus A
Published in Journal of medicinal chemistry (10.09.1998)
Published in Journal of medicinal chemistry (10.09.1998)
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Novel conformationally restricted tetracyclic analogs of Δ8-tetrahydrocannabinol
Khanolkar, Atmaram D., Lu, Dai, Fan, Pusheng, Tian, Xiaoyu, Makriyannis, Alexandros
Published in Bioorganic & medicinal chemistry letters (01.08.1999)
Published in Bioorganic & medicinal chemistry letters (01.08.1999)
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The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats
Sink, Kelly S, McLaughlin, Peter J, Wood, Jodi Anne T, Brown, Cara, Fan, Pusheng, Vemuri, V Kiran, Peng, Yan, Pang, Yan, Olszewska, Teresa, Olzewska, Teresa, Thakur, Ganesh A, Makriyannis, Alex, Parker, Linda A, Salamone, John D
Published in Neuropsychopharmacology (New York, N.Y.) (01.03.2008)
Published in Neuropsychopharmacology (New York, N.Y.) (01.03.2008)
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Human Cannabinoid Receptor 2 Ligand-Interaction Motif: Transmembrane Helix 2 Cysteine, C2.59(89), as Determinant of Classical Cannabinoid Agonist Activity and Binding Pose
Zhou, Han, Peng, Yan, Halikhedkar, Aneetha, Fan, Pusheng, Janero, David R, Thakur, Ganesh A, Mercier, Richard W, Sun, Xin, Ma, Xiaoyu, Makriyannis, Alexandros
Published in ACS chemical neuroscience (21.06.2017)
Published in ACS chemical neuroscience (21.06.2017)
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Erratum: The Novel Cannabinoid CB1 Receptor Neutral Antagonist Am4113 Suppresses Food Intake and Food-Reinforced Behavior but Does not Induce Signs of Nausea in Rats
Sink, Kelly S, McLaughlin, Peter J, Wood, Jodi Anne T, Brown, Cara, Fan, Pusheng, Vemuri, V Kiran, Pang, Yan, Olzewska, Teresa, Thakur, Ganesh A, Makriyannis, Alex, Parker, Linda A, Salamone, John D
Published in Neuropsychopharmacology (New York, N.Y.) (13.05.2008)
Published in Neuropsychopharmacology (New York, N.Y.) (13.05.2008)
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The Novel Cannabinoid CB1 Receptor Neutral Antagonist AM41 13 Suppresses Food Intake and Food-Reinforced Behavior but Does not Induce Signs of Nausea in Rats
SINK, Kelly S, MCLAUGHLIN, Peter J, PARKER, Linda A, SALAMONE, John D, WOOD, Jodi Anne T, BROWN, Cara, PUSHENG FAN, KIRAN VEMURI, V, YAN PANG, OLZEWSKA, Teresa, THAKUR, Ganesh A, MAKRIYANNIS, Alex
Published in Neuropsychopharmacology (New York, N.Y.) (2008)
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Published in Neuropsychopharmacology (New York, N.Y.) (2008)
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Head Group Analogs of Arachidonylethanolamide, the Endogenous Cannabinoid Ligand
Khanolkar, Atmaram D, Abadji, Vasiliki, Lin, Sonyuan, Hill, W. Adam G, Taha, Gihan, Abouzid, Khaled, Meng, Zhaoxing, Fan, Pusheng, Makriyannis, Alexandros
Published in Journal of medicinal chemistry (25.10.1996)
Published in Journal of medicinal chemistry (25.10.1996)
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Journal Article
The Novel Cannabinoid CB1 Receptor Neutral Antagonist Am4113 Suppresses Food Intake and Food-Reinforced Behavior but Does not Induce Signs of Nausea in Rats
Sink, Kelly S, Mclaughlin, Peter J, Wood, Jodi Anne T, Brown, Cara, Fan, Pusheng, Vemuri, V Kiran, Pang, Yan, Olzewska, Teresa, Thakur, Ganesh A, Makriyannis, Alex, Parker, Linda A, Salamone, John D
Published in Neuropsychopharmacology (New York, N.Y.) (01.06.2008)
Published in Neuropsychopharmacology (New York, N.Y.) (01.06.2008)
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The role of halogen substitution in classical cannabinoids: a CB1 pharmacophore model
Nikas, Spyros P, Grzybowska, Jolanta, Papahatjis, Demetris P, Charalambous, Avgui, Banijamali, Ali R, Chari, Ravi, Fan, Pusheng, Kourouli, Therapia, Lin, Sonyuan, Nitowski, Albert J, Marciniak, Gilbert, Guo, Yan, Li, Xiuyan, Wang, Chia-Lin J, Makriyannis, Alexandros
Published in The AAPS journal (01.12.2004)
Published in The AAPS journal (01.12.2004)
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Design and synthesis of the CB1 selective cannabinoid antagonist AM281: a potential human SPECT ligand
Lan, R, Gatley, J, Lu, Q, Fan, P, Fernando, S R, Volkow, N D, Pertwee, R, Makriyannis, A
Published in AAPS PharmSci (1999)
Published in AAPS PharmSci (1999)
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Unsaturated Side Chain β-11-Hydroxyhexahydrocannabinol Analogs
Busch-Petersen, Jakob, Hill, W. Adam, Fan, Pusheng, Khanolkar, Atmaram, Xie, Xuang-Qun, Tius, Marcus A, Makriyannis, Alexandros
Published in Journal of medicinal chemistry (13.09.1996)
Published in Journal of medicinal chemistry (13.09.1996)
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