The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth
FALLINI, Claudia, BASSELL, Gary J, ROSSOLL, Wilfried
Published in Human molecular genetics (15.08.2012)
Published in Human molecular genetics (15.08.2012)
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Journal Article
Traffic jam at the nuclear pore: All roads lead to nucleocytoplasmic transport defects in ALS/FTD
Fallini, Claudia, Khalil, Bilal, Smith, Courtney L., Rossoll, Wilfried
Published in Neurobiology of disease (01.07.2020)
Published in Neurobiology of disease (01.07.2020)
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Journal Article
Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons
Fallini, Claudia, Donlin-Asp, Paul G, Rouanet, Jeremy P, Bassell, Gary J, Rossoll, Wilfried
Published in The Journal of neuroscience (30.03.2016)
Published in The Journal of neuroscience (30.03.2016)
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Journal Article
Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis
Giampetruzzi, Anthony, Danielson, Eric W., Gumina, Valentina, Jeon, Maryangel, Boopathy, Sivakumar, Brown, Robert H., Ratti, Antonia, Landers, John E., Fallini, Claudia
Published in Nature communications (23.08.2019)
Published in Nature communications (23.08.2019)
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Journal Article
ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function
Baron, Desiree M., Fenton, Adam R., Saez-Atienzar, Sara, Giampetruzzi, Anthony, Sreeram, Aparna, Shankaracharya, Keagle, Pamela J., Doocy, Victoria R., Smith, Nathan J., Danielson, Eric W., Andresano, Megan, McCormack, Mary C., Garcia, Jaqueline, Bercier, Valérie, Van Den Bosch, Ludo, Brent, Jonathan R., Fallini, Claudia, Traynor, Bryan J., Holzbaur, Erika L.F., Landers, John E.
Published in Cell reports (Cambridge) (05.04.2022)
Published in Cell reports (Cambridge) (05.04.2022)
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Journal Article
The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly
Donlin-Asp, Paul G., Fallini, Claudia, Campos, Jazmin, Chou, Ching-Chieh, Merritt, Megan E., Phan, Han C., Bassell, Gary J., Rossoll, Wilfried
Published in Cell reports (Cambridge) (14.02.2017)
Published in Cell reports (Cambridge) (14.02.2017)
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Journal Article
Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination
Dammer, Eric B, Fallini, Claudia, Gozal, Yair M, Duong, Duc M, Rossoll, Wilfried, Xu, Ping, Lah, James J, Levey, Allan I, Peng, Junmin, Bassell, Gary J, Seyfried, Nicholas T
Published in PloS one (21.06.2012)
Published in PloS one (21.06.2012)
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Journal Article
ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation
Sama, Reddy Ranjith K., Fallini, Claudia, Gatto, Rodolfo, McKeon, Jeanne E., Song, Yuyu, Rotunno, Melissa S., Penaranda, Saul, Abdurakhmanov, Izrail, Landers, John E., Morfini, Gerardo, Brady, Scott T., Bosco, Daryl A.
Published in Scientific reports (08.03.2017)
Published in Scientific reports (08.03.2017)
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Journal Article
Post-transcriptional Regulation of Neuro-oncological Ventral Antigen 1 by the Neuronal RNA-binding Proteins ELAV
Ratti, Antonia, Fallini, Claudia, Colombrita, Claudia, Pascale, Alessia, Laforenza, Umberto, Quattrone, Alessandro, Silani, Vincenzo
Published in The Journal of biological chemistry (21.03.2008)
Published in The Journal of biological chemistry (21.03.2008)
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Journal Article
Early disruption of the CREB pathway drives dendritic morphological alterations in FTD/ALS cortical neurons
Jean Gregoire, Michelle, Sirtori, Riccardo, Donatelli, Liviana, Morgan Potts, Emily, Collins, Alicia, Zamor, Danielo, Katenka, Natallia, Fallini, Claudia
Published in Proceedings of the National Academy of Sciences - PNAS (03.12.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (03.12.2024)
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Journal Article
The survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons
Fallini, Claudia, Zhang, Honglai, Su, Yuehang, Silani, Vincenzo, Singer, Robert H, Rossoll, Wilfried, Bassell, Gary J
Published in The Journal of neuroscience (09.03.2011)
Published in The Journal of neuroscience (09.03.2011)
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Journal Article
Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis
Wu, Chi-Hong, Fallini, Claudia, Ticozzi, Nicola, Keagle, Pamela J., Sapp, Peter C., Piotrowska, Katarzyna, Lowe, Patrick, Koppers, Max, McKenna-Yasek, Diane, Baron, Desiree M., Kost, Jason E., Gonzalez-Perez, Paloma, Fox, Andrew D., Adams, Jenni, Taroni, Franco, Tiloca, Cinzia, Leclerc, Ashley Lyn, Chafe, Shawn C., Mangroo, Dev, Moore, Melissa J., Zitzewitz, Jill A., Xu, Zuo-Shang, van den Berg, Leonard H., Glass, Jonathan D., Siciliano, Gabriele, Cirulli, Elizabeth T., Goldstein, David B., Salachas, Francois, Meininger, Vincent, Rossoll, Wilfried, Ratti, Antonia, Gellera, Cinzia, Bosco, Daryl A., Bassell, Gary J., Silani, Vincenzo, Drory, Vivian E., Brown Jr, Robert H., Landers, John E.
Published in Nature (London) (23.08.2012)
Published in Nature (London) (23.08.2012)
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Journal Article
Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis
Smith, Bradley N, Topp, Simon D, Fallini, Claudia, Shibata, Hideki, Chen, Han-Jou, Troakes, Claire, King, Andrew, Ticozzi, Nicola, Kenna, Kevin P, Soragia-Gkazi, Athina, Miller, Jack W, Sato, Akane, Dias, Diana Marques, Jeon, Maryangel, Vance, Caroline, Wong, Chun Hao, de Majo, Martina, Kattuah, Wejdan, Mitchell, Jacqueline C, Scotter, Emma L, Parkin, Nicholas W, Sapp, Peter C, Nolan, Matthew, Nestor, Peter J, Simpson, Michael, Weale, Michael, Lek, Monkel, Baas, Frank, Vianney de Jong, J M, Ten Asbroek, Anneloor L M A, Redondo, Alberto Garcia, Esteban-Pérez, Jesús, Tiloca, Cinzia, Verde, Federico, Duga, Stefano, Leigh, Nigel, Pall, Hardev, Morrison, Karen E, Al-Chalabi, Ammar, Shaw, Pamela J, Kirby, Janine, Turner, Martin R, Talbot, Kevin, Hardiman, Orla, Glass, Jonathan D, De Belleroche, Jacqueline, Maki, Masatoshi, Moss, Stephen E, Miller, Christopher, Gellera, Cinzia, Ratti, Antonia, Al-Sarraj, Safa, Brown, Jr, Robert H, Silani, Vincenzo, Landers, John E, Shaw, Christopher E
Published in Science translational medicine (03.05.2017)
Published in Science translational medicine (03.05.2017)
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Journal Article
Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA‐binding protein IMP1 facilitates its trafficking into motor neuron axons
Fallini, Claudia, Rouanet, Jeremy P., Donlin‐Asp, Paul G., Guo, Peng, Zhang, Honglai, Singer, Robert H., Rossoll, Wilfried, Bassell, Gary J.
Published in Developmental neurobiology (Hoboken, N.J.) (01.03.2014)
Published in Developmental neurobiology (Hoboken, N.J.) (01.03.2014)
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Journal Article
TDP-43 and NOVA-1 RNA-binding proteins as competitive splicing regulators of the schizophrenia-associated TNIK gene
Gumina, Valentina, Colombrita, Claudia, Fallini, Claudia, Bossolasco, Patrizia, Maraschi, Anna Maria, Landers, John E., Silani, Vincenzo, Ratti, Antonia
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01.09.2019)
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01.09.2019)
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