Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase Domain
Grunewald, Susanne, Klug, Lillian R, Mühlenberg, Thomas, Lategahn, Jonas, Falkenhorst, Johanna, Town, Ajia, Ehrt, Christiane, Wardelmann, Eva, Hartmann, Wolfgang, Schildhaus, Hans-Ulrich, Treckmann, Juergen, Fletcher, Jonathan A, Jung, Sascha, Czodrowski, Paul, Miller, Stephen, Schmidt-Kittler, Oleg, Rauh, Daniel, Heinrich, Michael C, Bauer, Sebastian
Published in Cancer discovery (01.01.2021)
Published in Cancer discovery (01.01.2021)
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Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity
Möhrmann, Lino, Werner, Maximilian, Oleś, Małgorzata, Mock, Andreas, Uhrig, Sebastian, Jahn, Arne, Kreutzfeldt, Simon, Fröhlich, Martina, Hutter, Barbara, Paramasivam, Nagarajan, Richter, Daniela, Beck, Katja, Winter, Ulrike, Pfütze, Katrin, Heilig, Christoph E., Teleanu, Veronica, Lipka, Daniel B., Zapatka, Marc, Hanf, Dorothea, List, Catrin, Allgäuer, Michael, Penzel, Roland, Rüter, Gina, Jelas, Ivan, Hamacher, Rainer, Falkenhorst, Johanna, Wagner, Sebastian, Brandts, Christian H., Boerries, Melanie, Illert, Anna L., Metzeler, Klaus H., Westphalen, C. Benedikt, Desuki, Alexander, Kindler, Thomas, Folprecht, Gunnar, Weichert, Wilko, Brors, Benedikt, Stenzinger, Albrecht, Schröck, Evelin, Hübschmann, Daniel, Horak, Peter, Heining, Christoph, Fröhling, Stefan, Glimm, Hanno
Published in Nature communications (02.08.2022)
Published in Nature communications (02.08.2022)
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Localized Angiosarcoma, Not One Disease: A Retrospective Single-Center Study on Prognosis Depending on the Primary Site and Etiology
Schott, Inna, Liffers, Sven-Thorsten, Farzaliyev, Farhad, Falkenhorst, Johanna, Steinau, Hans-Ulrich, Treckmann, Jürgen-Walter, Podleska, Lars Erik, Pöttgen, Christoph, Schildhaus, Hans-Ulrich, Ahrens, Marit, Dirksen, Uta, Murat, Fatma-Zehra, Siveke, Jens T., Bauer, Sebastian, Hamacher, Rainer
Published in Sarcoma (2021)
Published in Sarcoma (2021)
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Community-driven development of a modified progression-free survival ratio for precision oncology
Mock, Andreas, Heilig, Christoph E, Kreutzfeldt, Simon, Huebschmann, Daniel, Heining, Christoph, Schröck, Evelin, Brors, Benedikt, Stenzinger, Albrecht, Jäger, Dirk, Schlenk, Richard, Glimm, Hanno, Fröhling, Stefan, Horak, Peter
Published in ESMO open (2019)
Published in ESMO open (2019)
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New therapeutic agents in gastrointestinal stromal tumours
Falkenhorst, Johanna, Hamacher, Rainer, Bauer, Sebastian
Published in Current opinion in oncology (01.07.2019)
Published in Current opinion in oncology (01.07.2019)
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Journal Article
Reply to Y. Xia et al
Bauer, Sebastian, Fletcher, Jonathan A, Rauh, Daniel, Falkenhorst, Johanna, Mühlenberg, Thomas
Published in Journal of clinical oncology (20.09.2024)
Published in Journal of clinical oncology (20.09.2024)
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Journal Article
Overall survival of patients with KIT-mutant metastatic GIST in the era of multiple kinase inhibitor availability
Haller, Valerie, Reiff, Carina, Hamacher, Rainer, Kostbade, Karina, Kaths, Moritz, Treckmann, Juergen, Bertram, Stefanie, Zaun, Yasmin, Bauer, Sebastian, Falkenhorst, Johanna
Published in Journal of cancer research and clinical oncology (09.11.2024)
Published in Journal of cancer research and clinical oncology (09.11.2024)
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Journal Article
Molecular subtypes of gastrointestinal stromal tumor requiring specific treatments
Pogorzelski, Michael, Falkenhorst, Johanna, Bauer, Sebastian
Published in Current opinion in oncology (01.07.2016)
Published in Current opinion in oncology (01.07.2016)
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Prognostic factors in clear cell sarcoma: an analysis of soft tissue sarcoma in 43 cases
Grothues, Janik, Hardes, Jendrik, Agaimy, Abbas, Collaud, Stephane, Podleska, Lars, Farzalyev, Farhad, Engel, Nina Myline, Hamacher, Rainer, Fletcher, Benjamin, Pöttgen, Christoph, Bertram, Stefanie, Schildhaus, Hans-Ulrich, Streitbürger, Arne, Bauer, Sebastian, Falkenhorst, Johanna
Published in Journal of cancer research and clinical oncology (13.11.2024)
Published in Journal of cancer research and clinical oncology (13.11.2024)
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Journal Article
Lower-dosing ponatinib in pre-treated GIST: Results of the POETIG phase II trial
Falkenhorst, Johanna, Hamacher, Rainer, Reichardt, Peter, Ivanyi, Philipp, Kasper, Bernd, Hohenberger, Peter, Hermes, Barbara, Kostbade, Karina, Pink, Daniel, Sülberg, Heiko, Metzenmacher, Martin, Crysandt, Martina, Bauer, Sebastian
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
KIT ATP-Binding Pocket/Activation Loop Mutations in GI Stromal Tumor: Emerging Mechanisms of Kinase Inhibitor Escape
Mühlenberg, Thomas, Falkenhorst, Johanna, Schulz, Tom, Fletcher, Benjamin S, Teuber, Alina, Krzeciesa, Dawid, Klooster, Isabella, Lundberg, Meijun, Wilson, Lydia, Lategahn, Jonas, von Mehren, Margaret, Grunewald, Susanne, Tüns, Alicia Isabell, Wardelmann, Eva, Sicklick, Jason K, Brahmi, Mehdi, Serrano, César, Schildhaus, Hans-Ulrich, Sievers, Sonja, Treckmann, Jürgen, Heinrich, Michael C, Raut, Chandrajit P, Ou, Wen-Bin, Marino-Enriquez, Adrian, George, Suzanne, Rauh, Daniel, Fletcher, Jonathan A, Bauer, Sebastian
Published in Journal of clinical oncology (20.04.2024)
Published in Journal of clinical oncology (20.04.2024)
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Journal Article
Adjuvant Imatinib in Patients with GIST Harboring Exon 9 KIT Mutations: Results from a Multi-institutional European Retrospective Study
Vincenzi, Bruno, Napolitano, Andrea, Fiocco, Marta, Mir, Olivier, Rutkowski, Piotr, Blay, Jean-Yves, Reichardt, Peter, Joensuu, Heikki, Fumagalli, Elena, Gennatas, Spyridon, Hindi, Nadia, Nannini, Margherita, Spalato Ceruso, Mariella, Italiano, Antoine, Grignani, Giovanni, Brunello, Antonella, Gasperoni, Silvia, De Pas, Tommaso, Badalamenti, Giuseppe, Pantaleo, Maria A, van Houdt, Winan J, IJzerman, Nikki S, Steeghs, Neeltje, Gelderblom, Hans, Desar, Ingrid M E, Falkenhorst, Johanna, Silletta, Marianna, Sbaraglia, Marta, Tonini, Giuseppe, Martin-Broto, Javier, Hohenberger, Peter, Le Cesne, Axel, Jones, Robin L, Dei Tos, Angelo P, Gronchi, Alessandro, Bauer, Sebastian, Casali, Paolo G
Published in Clinical cancer research (14.04.2022)
Published in Clinical cancer research (14.04.2022)
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Fibroblast Activation Protein α-Directed Imaging and Therapy of Solitary Fibrous Tumor
Hamacher, Rainer, Pabst, Kim M, Cheung, Phyllis F, Heilig, Christoph E, Hüllein, Jennifer, Liffers, Sven-Thorsten, Borchert, Sabrina, Costa, Pedro Fragoso, Schaarschmidt, Benedikt M, Kessler, Lukas, Miera, Monika A, Droste, Margret, Akbulut, Merve, Falkenhorst, Johanna, Zarrad, Fadi, Kostbade, Karina, Mavroeidi, Ilektra A, Glimm, Hanno, Umutlu, Lale, Schuler, Martin, Hübschmann, Daniel, Bauer, Sebastian, Fröhling, Stefan, Herrmann, Ken, Siveke, Jens T, Schildhaus, Hans-Ulrich, Fendler, Wolfgang P
Published in Journal of Nuclear Medicine (01.02.2024)
Published in Journal of Nuclear Medicine (01.02.2024)
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Journal Article
Abstract 3005: Comprehensive profile of platelet derived growth factor receptor alpha (PDGFRA) mutations in gastrointestinal stromal tumors
Khosroyani, Homma, Klug, Lillian R., Town, Ajia, Lategahn, Jonas, Falkenhorst, Johanna, Grunewald, Susanne, Mühlenberg, Thomas, Ehrt, Christiane, Wardelmann, Eve, Hartmann, Wolfgang, Schildhaus, Hans-Ulrich, Jung, Sascha, Czodrowski, Paul, Agaimy, Abbas, Rutkowski, Piotr, Rauh, Daniel, Bauer, Sebastian, Heinrich, Michael C.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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