Diverse origins of the myofibroblast—implications for kidney fibrosis
Falke, Lucas L., Gholizadeh, Shima, Goldschmeding, Roel, Kok, Robbert J., Nguyen, Tri Q.
Published in Nature reviews. Nephrology (01.04.2015)
Published in Nature reviews. Nephrology (01.04.2015)
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Journal Article
Deregulation of Hippo-TAZ pathway during renal injury confers a fibrotic maladaptive phenotype
Anorga, Sandybell, Overstreet, Jessica M, Falke, Lucas L, Tang, Jiaqi, Goldschmeding, Roel G, Higgins, Paul J, Samarakoon, Rohan
Published in The FASEB journal (01.05.2018)
Published in The FASEB journal (01.05.2018)
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Journal Article
Targeting CTGF, EGF and PDGF pathways to prevent progression of kidney disease
Kok, Helena M., Falke, Lucas L., Goldschmeding, Roel, Nguyen, Tri Q.
Published in Nature reviews. Nephrology (01.12.2014)
Published in Nature reviews. Nephrology (01.12.2014)
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Journal Article
Connective tissue growth factor regulates fibrosis-associated renal lymphangiogenesis
Kinashi, Hiroshi, Falke, Lucas L., Nguyen, Tri Q., Bovenschen, Niels, Aten, Jan, Leask, Andrew, Ito, Yasuhiko, Goldschmeding, Roel
Published in Kidney international (01.10.2017)
Published in Kidney international (01.10.2017)
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Journal Article
Cellular Senescence and the Kidney: Potential Therapeutic Targets and Tools
Knoppert, Sebastian N, Valentijn, Floris A, Nguyen, Tri Q, Goldschmeding, Roel, Falke, Lucas L
Published in Frontiers in pharmacology (12.07.2019)
Published in Frontiers in pharmacology (12.07.2019)
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Journal Article
CCN2 (Cellular Communication Network Factor 2) Deletion Alters Vascular Integrity and Function Predisposing to Aneurysm Formation
Rodrigues-Díez, Raúl R, Tejera-Muñoz, Antonio, Esteban, Vanesa, Steffensen, Lasse B, Rodrigues-Díez, Raquel, Orejudo, Macarena, Rayego-Mateos, Sandra, Falke, Lucas L, Cannata-Ortiz, Pablo, Ortiz, Alberto, Egido, Jesus, Mallat, Ziad, Briones Ana, M, Bajo, M Auxiliadora, Goldschmeding, Roel, Ruiz-Ortega, Marta
Published in Hypertension (Dallas, Tex. 1979) (01.03.2022)
Published in Hypertension (Dallas, Tex. 1979) (01.03.2022)
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Journal Article
Connective tissue growth factor induces renal fibrosis via epidermal growth factor receptor activation
Rayego‐Mateos, Sandra, Morgado‐Pascual, José Luis, Rodrigues‐Diez, Raúl R, Rodrigues‐Diez, Raquel, Falke, Lucas L, Mezzano, Sergio, Ortiz, Alberto, Egido, Jesús, Goldschmeding, Roel, Ruiz‐Ortega, Marta
Published in The Journal of pathology (01.02.2018)
Published in The Journal of pathology (01.02.2018)
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Journal Article
Nephronophthisis-associated CEP164 regulates cell cycle progression, apoptosis and epithelial-to-mesenchymal transition
Slaats, Gisela G, Ghosh, Amiya K, Falke, Lucas L, Le Corre, Stéphanie, Shaltiel, Indra A, van de Hoek, Glenn, Klasson, Timothy D, Stokman, Marijn F, Logister, Ive, Verhaar, Marianne C, Goldschmeding, Roel, Nguyen, Tri Q, Drummond, Iain A, Hildebrandt, Friedhelm, Giles, Rachel H
Published in PLoS genetics (01.10.2014)
Published in PLoS genetics (01.10.2014)
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Journal Article
Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats
Frýdlová, Jana, Přikryl, Petr, Truksa, Jaroslav, Falke, Lucas L, Du, Xin, Gurieva, Iuliia, Vokurka, Martin, Krijt, Jan
Published in PloS one (04.02.2016)
Published in PloS one (04.02.2016)
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Journal Article
Age-dependent shifts in renal response to injury relate to altered BMP6/CTGF expression and signaling
Falke, Lucas L, Kinashi, Hiroshi, Dendooven, Amelie, Broekhuizen, Roel, Stoop, Reinout, Joles, Jaap A, Nguyen, Tri Q, Goldschmeding, Roel
Published in American journal of physiology. Renal physiology (01.11.2016)
Published in American journal of physiology. Renal physiology (01.11.2016)
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Journal Article
CCN2 Aggravates the Immediate Oxidative Stress-DNA Damage Response following Renal Ischemia-Reperfusion Injury
Valentijn, Floris A, Knoppert, Sebastiaan N, Pissas, Georgios, Rodrigues-Diez, Raúl R, Marquez-Exposito, Laura, Broekhuizen, Roel, Mokry, Michal, Kester, Lennart A, Falke, Lucas L, Goldschmeding, Roel, Ruiz-Ortega, Marta, Eleftheriadis, Theodoros, Nguyen, Tri Q
Published in Antioxidants (20.12.2021)
Published in Antioxidants (20.12.2021)
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Journal Article
Dialysis associated β2-microglobulin amyloidosis occurs even in the era of high-flux dialyzers
Falke, Lucas L., Maas, Sybren L. N., Rosati, Stefano, Logtenberg, Susan J. J.
Published in Amyloid (02.10.2018)
Published in Amyloid (02.10.2018)
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Journal Article
CCN2 reduction mediates protective effects of BMP7 treatment in obstructive nephropathy
Falke, Lucas L., Leeuwis, Jan Willem, Lyons, Karen M., Mummery, Christine L., Nguyen, Tri Q., Goldschmeding, Roel
Published in Journal of cell communication and signaling (01.03.2017)
Published in Journal of cell communication and signaling (01.03.2017)
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Journal Article
Cellular communication network 2 (connective tissue growth factor) aggravates acute DNA damage and subsequent DNA damage response-senescence-fibrosis following kidney ischemia reperfusion injury
Valentijn, Floris A., Knoppert, Sebastiaan N., Marquez-Exposito, Laura, Rodrigues-Diez, Raúl R., Pissas, Georgios, Tang, Jiaqi, Tejedor-Santamaria, Lucia, Broekhuizen, Roel, Samarakoon, Rohan, Eleftheriadis, Theodoros, Goldschmeding, Roel, Nguyen, Tri Q., Ruiz-Ortega, Marta, Falke, Lucas L.
Published in Kidney international (01.12.2022)
Published in Kidney international (01.12.2022)
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Journal Article
Loss of expression of protein phosphatase magnesium-dependent 1A during kidney injury promotes fibrotic maladaptive repair
Samarakoon, Rohan, Rehfuss, Alexandra, Khakoo, Nidah S, Falke, Lucas L, Dobberfuhl, Amy D, Helo, Sevann, Overstreet, Jessica M, Goldschmeding, Roel, Higgins, Paul J
Published in The FASEB journal (01.10.2016)
Published in The FASEB journal (01.10.2016)
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Journal Article
Local therapeutic efficacy with reduced systemic side effects by rapamycin-loaded subcapsular microspheres
Falke, Lucas L, van Vuuren, Stefan H, Kazazi-Hyseni, Filis, Ramazani, Farshad, Nguyen, Tri Q, Veldhuis, Gert J, Maarseveen, Erik M, Zandstra, Jurjen, Zuidema, Johan, Duque, Luisa F, Steendam, Rob, Popa, Eliane R, Kok, Robbert Jan, Goldschmeding, Roel
Published in Biomaterials (01.02.2015)
Published in Biomaterials (01.02.2015)
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Journal Article
CTGF knockout does not affect cardiac hypertrophy and fibrosis formation upon chronic pressure overload
Fontes, Magda S.C, Kessler, Elise L, van Stuijvenberg, Leonie, Brans, Maike A, Falke, Lucas L, Kok, Bart, Leask, Andrew, van Rijen, Harold V.M, Vos, Marc A, Goldschmeding, Roel, van Veen, Toon A.B
Published in Journal of molecular and cellular cardiology (01.11.2015)
Published in Journal of molecular and cellular cardiology (01.11.2015)
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Journal Article
A perspective on anti-CCN2 therapy for chronic kidney disease
Falke, Lucas L, Goldschmeding, Roel, Nguyen, Tri Quang
Published in Nephrology, dialysis, transplantation (01.02.2014)
Published in Nephrology, dialysis, transplantation (01.02.2014)
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Journal Article
Histological characteristics of Acute Tubular Injury during Delayed Graft Function predict renal function after renal transplantation
Pieters, Tobias T., Falke, Lucas L., Nguyen, Tri Q., Verhaar, Marianne C., Florquin, Sandrine, Bemelman, Frederike J., Kers, Jesper, Vanhove, Thomas, Kuypers, Dirk, Goldschmeding, Roel, Rookmaaker, Maarten B.
Published in Physiological reports (01.03.2019)
Published in Physiological reports (01.03.2019)
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Journal Article