Large-scale analysis of branchpoint usage across species and cell lines
Taggart, Allison J, Lin, Chien-Ling, Shrestha, Barsha, Heintzelman, Claire, Kim, Seongwon, Fairbrother, William G
Published in Genome research (01.04.2017)
Published in Genome research (01.04.2017)
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Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genes
Lim, Kian Huat, Ferraris, Luciana, Filloux, Madeleine E., Raphae, Benjamin J., Fairbrother, William G.
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2011)
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Journal Article
Massively parallel reporter assays discover de novo exonic splicing mutants in paralogs of Autism genes
Rhine, Christy L, Neil, Christopher, Wang, Jing, Maguire, Samantha, Buerer, Luke, Salomon, Mitchell, Meremikwu, Ijeoma C, Kim, Juliana, Strande, Natasha T, Fairbrother, William G
Published in PLoS genetics (20.01.2022)
Published in PLoS genetics (20.01.2022)
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Journal Article
Mutational bias and the protein code shape the evolution of splicing enhancers
Rong, Stephen, Buerer, Luke, Rhine, Christy L., Wang, Jing, Cygan, Kamil J., Fairbrother, William G.
Published in Nature communications (05.06.2020)
Published in Nature communications (05.06.2020)
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Journal Article
The importance of p53 pathway genetics in inherited and somatic cancer genomes
Stracquadanio, Giovanni, Wang, Xuting, Wallace, Marsha D., Grawenda, Anna M., Zhang, Ping, Hewitt, Juliet, Zeron-Medina, Jorge, Castro-Giner, Francesc, Tomlinson, Ian P., Goding, Colin R., Cygan, Kamil J., Fairbrother, William G., Thomas, Laurent F., Sætrom, Pål, Gemignani, Federica, Landi, Stefano, Schuster-Böckler, Benjamin, Bell, Douglas A., Bond, Gareth L.
Published in Nature reviews. Cancer (01.04.2016)
Published in Nature reviews. Cancer (01.04.2016)
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Journal Article
Hotspot exons are common targets of splicing perturbations
Glidden, David T., Buerer, Jeramiah L., Saueressig, Camillo F., Fairbrother, William G.
Published in Nature communications (12.05.2021)
Published in Nature communications (12.05.2021)
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Journal Article
The unusual gene architecture of polyubiquitin is created by dual-specific splice sites
Duan, Chaorui, Mooney, Truman, Buerer, Luke, Bowers, Cory, Rong, Stephen, Kim, Seong Won, Fredericks, Alger M, Monaghan, Sean F, Fairbrother, William G
Published in Genome Biology (24.01.2024)
Published in Genome Biology (24.01.2024)
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Journal Article
Hereditary cancer genes are highly susceptible to splicing mutations
Rhine, Christy L, Cygan, Kamil J, Soemedi, Rachel, Maguire, Samantha, Murray, Michael F, Monaghan, Sean F, Fairbrother, William G
Published in PLoS genetics (05.03.2018)
Published in PLoS genetics (05.03.2018)
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Journal Article
Recessive truncating titin gene, TTN, mutations presenting as centronuclear myopathy
Ceyhan-Birsoy, Ozge, Agrawal, Pankaj B, Hidalgo, Carlos, Schmitz-Abe, Klaus, DeChene, Elizabeth T, Swanson, Lindsay C, Soemedi, Rachel, Vasli, Nasim, Iannaccone, Susan T, Shieh, Perry B, Shur, Natasha, Dennison, Jane M, Lawlor, Michael W, Laporte, Jocelyn, Markianos, Kyriacos, Fairbrother, William G, Granzier, Henk, Beggs, Alan H
Published in Neurology (01.10.2013)
Published in Neurology (01.10.2013)
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Journal Article
The debranching enzyme Dbr1 regulates lariat turnover and intron splicing
Buerer, Luke, Clark, Nathaniel E., Welch, Anastasia, Duan, Chaorui, Taggart, Allison J., Townley, Brittany A., Wang, Jing, Soemedi, Rachel, Rong, Stephen, Lin, Chien-Ling, Zeng, Yi, Katolik, Adam, Staley, Jonathan P., Damha, Masad J., Mosammaparast, Nima, Fairbrother, William G.
Published in Nature communications (30.05.2024)
Published in Nature communications (30.05.2024)
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Journal Article
Deep RNA sequencing of intensive care unit patients with COVID-19
Fredericks, Alger M., Jentzsch, Maximilian S., Cioffi, William G., Cohen, Maya, Fairbrother, William G., Gandhi, Shivam J., Harrington, Elizabeth O., Nau, Gerard J., Reichner, Jonathan S., Ventetuolo, Corey E., Levy, Mitchell M., Ayala, Alfred, Monaghan, Sean F.
Published in Scientific reports (21.09.2022)
Published in Scientific reports (21.09.2022)
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Journal Article
A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress
Kang, Jinsuk, Gemberling, Matthew, Nakamura, Mitsuhiro, Whitby, Frank G, Handa, Hiroshi, Fairbrother, William G, Tantin, Dean
Published in Genes & development (15.01.2009)
Published in Genes & development (15.01.2009)
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Journal Article
Soluble programmed cell death receptor-1 (sPD-1): a potential biomarker with anti-inflammatory properties in human and experimental acute respiratory distress syndrome (ARDS)
Monaghan, Sean F, Chung, Chun-Shiang, Chen, Yaping, Lomas-Neira, Joanne, Fairbrother, William G, Heffernan, Daithi S, Cioffi, William G, Ayala, Alfred
Published in Journal of translational medicine (11.11.2016)
Published in Journal of translational medicine (11.11.2016)
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Journal Article
Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness
Monaghan, Sean F, Banerjee, Debasree, Chung, Chun-Shiang, Lomas-Neira, Joanne, Cygan, Kamil J, Rhine, Christy L, Fairbrother, William G, Heffernan, Daithi S, Levy, Mitchell M, Cioffi, William G, Ayala, Alfred
Published in Molecular medicine (Cambridge, Mass.) (18.06.2018)
Published in Molecular medicine (Cambridge, Mass.) (18.06.2018)
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Journal Article
RNA-Binding Proteins: Splicing Factors and Disease
Fredericks, Alger M, Cygan, Kamil J, Brown, Brian A, Fairbrother, William G
Published in Biomolecules (Basel, Switzerland) (13.05.2015)
Published in Biomolecules (Basel, Switzerland) (13.05.2015)
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Journal Article
Single nucleotide polymorphism-based validation of exonic splicing enhancers
Fairbrother, William G, Holste, Dirk, Burge, Christopher B, Sharp, Phillip A
Published in PLoS biology (01.09.2004)
Published in PLoS biology (01.09.2004)
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Journal Article
Non-cancer-related pathogenic germline variants and expression consequences in ten-thousand cancer genomes
Wang, Zishan, Fan, Xiao, Shen, Yufeng, Pagadala, Meghana S, Signer, Rebecca, Cygan, Kamil J, Fairbrother, William G, Carter, Hannah, Chung, Wendy K, Huang, Kuan-Lin
Published in Genome medicine (09.09.2021)
Published in Genome medicine (09.09.2021)
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