In Vitro Evaluation of the Potential for Drug Interactions by Salidroside
Kasprzyk, Philip G., Tremaine, Larry, Fahmi, Odette A., Weng, Jing-Ke
Published in Nutrients (25.08.2023)
Published in Nutrients (25.08.2023)
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Journal Article
A Combined Model for Predicting CYP3A4 Clinical Net Drug-Drug Interaction Based on CYP3A4 Inhibition, Inactivation, and Induction Determined in Vitro
FAHMI, Odette A, MAURER, Tristan S, KISH, Mary, CARDENAS, Edwin, BOLDT, Sherri, NETTLETON, David
Published in Drug metabolism and disposition (01.08.2008)
Published in Drug metabolism and disposition (01.08.2008)
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Journal Article
Cytochrome P450 3A4 mRNA is a more reliable marker than CYP3A4 activity for detecting pregnane X receptor-activated induction of drug-metabolizing enzymes
Fahmi, Odette A, Kish, Mary, Boldt, Sherri, Obach, R Scott
Published in Drug metabolism and disposition (01.09.2010)
Published in Drug metabolism and disposition (01.09.2010)
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Journal Article
Comparison of Different Algorithms for Predicting Clinical Drug-Drug Interactions, Based on the Use of CYP3A4 in Vitro Data: Predictions of Compounds as Precipitants of Interaction
Fahmi, Odette A, Hurst, Susan, Plowchalk, David, Cook, Jack, Guo, Feng, Youdim, Kuresh, Dickins, Maurice, Phipps, Alex, Darekar, Amanda, Hyland, Ruth, Obach, R Scott
Published in Drug metabolism and disposition (01.08.2009)
Published in Drug metabolism and disposition (01.08.2009)
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Journal Article
Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control
Hariparsad, Niresh, Ramsden, Diane, Palamanda, Jairam, Dekeyser, Joshua G, Fahmi, Odette A, Kenny, Jane R, Einolf, Heidi, Mohutsky, Michael, Pardon, Magalie, Siu, Y Amy, Chen, Liangfu, Sinz, Michael, Jones, Barry, Walsky, Robert, Dallas, Shannon, Balani, Suresh K, Zhang, George, Buckley, David, Tweedie, Donald
Published in Drug metabolism and disposition (01.10.2017)
Published in Drug metabolism and disposition (01.10.2017)
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Journal Article
Evaluation of models for predicting drug-drug interactions due to induction
Fahmi, Odette A, Ripp, Sharon L
Published in Expert opinion on drug metabolism & toxicology (01.11.2010)
Published in Expert opinion on drug metabolism & toxicology (01.11.2010)
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Journal Article
Unexpected effect of rifampin on the pharmacokinetics of linezolid: in silico and in vitro approaches to explain its mechanism
Gandelman, Kuan, Zhu, Tong, Fahmi, Odette A, Glue, Paul, Lian, Kenny, Obach, R Scott, Damle, Bharat
Published in Journal of clinical pharmacology (01.02.2011)
Published in Journal of clinical pharmacology (01.02.2011)
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Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome
Dong, Jennifer Q, Gosset, James R, Fahmi, Odette A, Lin, Zhiwu, Chabot, Jeffrey R, Terra, Steven G, Le, Vu, Chidsey, Kristin, Nouri, Parya, Kim, Albert, Buckbinder, Leonard, Kalgutkar, Amit S
Published in Drug metabolism and disposition (01.05.2017)
Published in Drug metabolism and disposition (01.05.2017)
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Journal Article
Quantitative prediction of repaglinide-rifampicin complex drug interactions using dynamic and static mechanistic models: delineating differential CYP3A4 induction and OATP1B1 inhibition potential of rifampicin
Varma, Manthena V S, Lin, Jian, Bi, Yi-An, Rotter, Charles J, Fahmi, Odette A, Lam, Justine L, El-Kattan, Ayman F, Goosen, Theunis C, Lai, Yurong
Published in Drug metabolism and disposition (01.05.2013)
Published in Drug metabolism and disposition (01.05.2013)
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Journal Article
Use of Immortalized Human Hepatocytes to Predict the Magnitude of Clinical Drug-Drug Interactions Caused by CYP3A4 Induction
RIPP, Sharon L, MILLS, Jessica B, FAHMI, Odette A, TREVENA, Kristen A, LIRAS, Jennifer L, MAURER, Tristan S, DE MORAIS, Sonia M
Published in Drug metabolism and disposition (01.10.2006)
Published in Drug metabolism and disposition (01.10.2006)
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Journal Article
A novel method using confocal laser scanning microscopy for sensitive measurement of P-glycoprotein-mediated transport activity in Caco-2 cells
Wakuda, Hirokazu, Nejime, Namie, Tada, Yukari, Kagota, Satomi, Fahmi, Odette A, Umegaki, Keizo, Yamada, Shizuo, Shinozuka, Kazumasa
Published in Journal of pharmacy and pharmacology (01.08.2011)
Published in Journal of pharmacy and pharmacology (01.08.2011)
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Journal Article
Evaluation of CYP2B6 Induction and Prediction of Clinical Drug-Drug Interactions: Considerations from the IQ Consortium Induction Working Group-An Industry Perspective
Fahmi, Odette A, Shebley, Mohamad, Palamanda, Jairam, Sinz, Michael W, Ramsden, Diane, Einolf, Heidi J, Chen, Liangfu, Wang, Hongbing
Published in Drug metabolism and disposition (01.10.2016)
Published in Drug metabolism and disposition (01.10.2016)
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Journal Article
Critical review of preclinical approaches to investigate cytochrome p450-mediated therapeutic protein drug-drug interactions and recommendations for best practices: a white paper
Evers, Raymond, Dallas, Shannon, Dickmann, Leslie J, Fahmi, Odette A, Kenny, Jane R, Kraynov, Eugenia, Nguyen, Theresa, Patel, Aarti H, Slatter, J Greg, Zhang, Lei
Published in Drug metabolism and disposition (01.09.2013)
Published in Drug metabolism and disposition (01.09.2013)
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Journal Article
PREDICTION OF DRUG-DRUG INTERACTIONS FROM IN VITRO INDUCTION DATA : Application of the Relative Induction Score Approach Using Cryopreserved Human Hepatocytes
FAHMI, Odette A, BOLDT, Sherri, KISH, Mary, OBACH, R. Scott, TREMAINE, Larry M
Published in Drug metabolism and disposition (01.09.2008)
Published in Drug metabolism and disposition (01.09.2008)
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Journal Article
Lack of effect of tofacitinib (CP‐690,550) on the pharmacokinetics of the CYP3A4 substrate midazolam in healthy volunteers: confirmation of in vitro data
Gupta, Pankaj, Alvey, Christine, Wang, Rong, Dowty, Martin E., Fahmi, Odette A., Walsky, Robert L., Riese, Richard J., Krishnaswami, Sriram
Published in British journal of clinical pharmacology (01.07.2012)
Published in British journal of clinical pharmacology (01.07.2012)
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Journal Article
Utility of DPX2 cells for predicting CYP3A induction-mediated drug-drug interactions and associated structure-activity relationships
Fahmi, Odette A, Raucy, Judy L, Ponce, Elsa, Hassanali, Saleema, Lasker, Jerome M
Published in Drug metabolism and disposition (01.11.2012)
Published in Drug metabolism and disposition (01.11.2012)
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Journal Article
How Current Understanding of Clearance Mechanisms and Pharmacodynamics of Therapeutic Proteins Can Be Applied for Evaluation of Their Drug-Drug Interaction Potential
KRAYNOV, Eugenia, MARTIN, Steven W, AWWAD, Michel, WANG, Diane, HURST, Susan, FAHMI, Odette A, DOWTY, Martin, CRONENBERGER, Carol, LOI, Cho-Ming, KUANG, Bing, FIELDS, Owen, FOUNTAIN, Scott
Published in Drug metabolism and disposition (01.10.2011)
Published in Drug metabolism and disposition (01.10.2011)
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Journal Article
The time to move cytochrome p450 induction into mainstream pharmacology is long overdue
Smith, Dennis A, Dickins, Maurice, Fahmi, Odette A, Iwasaki, Kazuhide, Lee, Caroline, Obach, R Scott, Padbury, Guy, De Morais, Sonia M, Ripp, Sharon L, Stevens, Jeff, Voorman, Richard, Youdim, Kuresh
Published in Drug metabolism and disposition (01.04.2007)
Published in Drug metabolism and disposition (01.04.2007)
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