Use of a Canine Model of Atopic Dermatitis to Investigate the Efficacy of a CCR4 Antagonist in Allergen-Induced Skin Inflammation in a Randomized Study
Murray, Clare, Ahrens, Kim, Devalaraja, Matt, Dymond, Mike, Fagura, Malbinder, Hargreaves, Adam, Holt, Alison, Peers, Ian, Price, Sally, Reens, Jaimini, Riley, Rob, Marsella, Rosanna
Published in Journal of investigative dermatology (01.03.2016)
Published in Journal of investigative dermatology (01.03.2016)
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Journal Article
Human stem cell osteoblastogenesis mediated by novel glycogen synthase kinase 3 inhibitors induces bone formation and a unique bone turnover biomarker profile in rats
Gilmour, Peter S., O'Shea, Patrick J., Fagura, Malbinder, Pilling, James E., Sanganee, Hitesh, Wada, Hiroki, Courtney, Paul F., Kavanagh, Stefan, Hall, Peter A., Escott, K. Jane
Published in Toxicology and applied pharmacology (15.10.2013)
Published in Toxicology and applied pharmacology (15.10.2013)
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Journal Article
Hit-to-Lead studies: The discovery of potent adamantane amide P2X 7 receptor antagonists
Baxter, Andrew, Bent, Janice, Bowers, Keith, Braddock, Martin, Brough, Steve, Fagura, Malbinder, Lawson, Mandy, McInally, Tom, Mortimore, Mike, Robertson, Mark, Weaver, Richard, Webborn, Peter
Published in Bioorganic & medicinal chemistry letters (17.11.2003)
Published in Bioorganic & medicinal chemistry letters (17.11.2003)
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Journal Article
Discovery of Potent and Selective Adamantane-Based Small-Molecule P2X 7 Receptor Antagonists/Interleukin-1β Inhibitors
Furber, Mark, Alcaraz, Lilian, Bent, Janice E., Beyerbach, Armin, Bowers, Keith, Braddock, Martin, Caffrey, Moya V., Cladingboel, David, Collington, John, Donald, David K., Fagura, Malbinder, Ince, Frank, Kinchin, Elizabeth C., Laurent, Celine, Lawson, Mandy, Luker, Timothy J., Mortimore, Michael M. P., Pimm, Austen D., Riley, Robert J., Roberts, Nicola, Robertson, Mark, Theaker, Jill, Thorne, Philip V., Weaver, Richard, Webborn, Peter, Willis, Paul
Published in Journal of medicinal chemistry (29.11.2007)
Published in Journal of medicinal chemistry (29.11.2007)
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Journal Article
Discovery of potent and selective adamantane-based small-molecule P2X(7) receptor antagonists/interleukin-1 beta,6 inhibitors
Furber, Mark, Alcaraz, Lilian, Bent, Janice E., Beyerbach, Armin, Bowers, Keith, Braddock, Martin, Caffrey, Moya V., Cladingboel, David, Collington, John, Donald, David K., Fagura, Malbinder, Ince, Frank, Kinchin, Elizabeth C., Laurent, Celine, Lawson, Mandy, Luker, Timothy J., Mortimore, Michael M. P., Pimm, Austen D., Riley, Robert J., Roberts, Nicola, Robertson, Mark, Theaker, Jill, Thorne, Philip V., Weaver, Richard, Webborn, Peter, Willis, Paul
Published in Journal of medicinal chemistry (29.11.2007)
Published in Journal of medicinal chemistry (29.11.2007)
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Journal Article
Discovery of pyrazoles as novel FPR1 antagonists
Morley, Andrew D., Cook, Andrew, King, Sarah, Roberts, Bryan, Lever, Sarah, Weaver, Richard, MacDonald, Cathy, Unitt, John, Fagura, Malbinder, Phillips, Tim, Lewis, Richard, Wenlock, Mark
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
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Journal Article
Discovery of small molecule human FPR1 receptor antagonists
Unitt, John, Fagura, Malbinder, Phillips, Tim, King, Sarah, Perry, Matthew, Morley, Andrew, MacDonald, Cathy, Weaver, Richard, Christie, Jadeen, Barber, Simon, Mohammed, Rukhsana, Paul, Melanie, Cook, Andrew, Baxter, Andrew
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
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Journal Article
Discovery of potent and selective adamantane-based small-molecule P2X(7) receptor antagonists/interleukin-1beta inhibitors
Furber, Mark, Alcaraz, Lilian, Bent, Janice E, Beyerbach, Armin, Bowers, Keith, Braddock, Martin, Caffrey, Moya V, Cladingboel, David, Collington, John, Donald, David K, Fagura, Malbinder, Ince, Frank, Kinchin, Elizabeth C, Laurent, Celine, Lawson, Mandy, Luker, Timothy J, Mortimore, Michael M P, Pimm, Austen D, Riley, Robert J, Roberts, Nicola, Robertson, Mark, Theaker, Jill, Thorne, Philip V, Weaver, Richard, Webborn, Peter, Willis, Paul
Published in Journal of medicinal chemistry (29.11.2007)
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Published in Journal of medicinal chemistry (29.11.2007)
Journal Article
Discovery of Potent and Selective Adamantane-Based Small-Molecule P2X7 Receptor Antagonists/Interleukin-1β Inhibitors
Furber, Mark, Alcaraz, Lilian, Bent, Janice E, Beyerbach, Armin, Bowers, Keith, Braddock, Martin, Caffrey, Moya V, Cladingboel, David, Collington, John, Donald, David K, Fagura, Malbinder, Ince, Frank, Kinchin, Elizabeth C, Laurent, Celine, Lawson, Mandy, Luker, Timothy J, Mortimore, Michael M. P, Pimm, Austen D, Riley, Robert J, Roberts, Nicola, Robertson, Mark, Theaker, Jill, Thorne, Philip V, Weaver, Richard, Webborn, Peter, Willis, Paul
Published in Journal of medicinal chemistry (29.11.2007)
Published in Journal of medicinal chemistry (29.11.2007)
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Journal Article
Hit-to-Lead studies: The discovery of potent adamantane amide P2X7 receptor antagonists
BAXTER, Andrew, BENT, Janice, WEAVER, Richard, WEBBORN, Peter, BOWERS, Keith, BRADDOCK, Martin, BROUGH, Steve, FAGURA, Malbinder, LAWSON, Mandy, MCLNALLY, Tom, MORTIMORE, Mike, ROBERTSON, Mark
Published in Bioorganic & medicinal chemistry letters (17.11.2003)
Published in Bioorganic & medicinal chemistry letters (17.11.2003)
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Journal Article
Adventures in the pharmacological analysis of P2 receptors
Fagura, Malbinder S., Jarvis, Gavin E., Dougall, Iain G., Leff, Paul
Published in Journal of the autonomic nervous system (03.07.2000)
Published in Journal of the autonomic nervous system (03.07.2000)
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Journal Article