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Published in ChemMedChem (07.03.2011)
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Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500)
Black, W. Cameron, Abdoli, Abbas, An, Xiuli, Auger, Anick, Beaulieu, Patrick, Bernatchez, Michel, Caron, Cathy, Chefson, Amandine, Crane, Sheldon, Diallo, Mohamed, Dorich, Stéphane, Fader, Lee D., Ferraro, Gino B., Fournier, Sara, Gao, Qi, Ginzburg, Yelena, Hamel, Martine, Han, Yongshuai, Jones, Paul, Lanoix, Stéphanie, Lacbay, Cyrus M., Leclaire, Marie-Eve, Levy, Maayan, Mamane, Yael, Mulani, Amina, Papp, Robert, Pellerin, Charles, Picard, Audrey, Skeldon, Alexander, Skorey, Kathryn, Stocco, Rino, St.-Onge, Miguel, Truchon, Jean-François, Truong, Vouy Linh, Zimmermann, Michal, Zinda, Michael, Roulston, Anne
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Published in Bioorganic & medicinal chemistry letters (15.07.2023)
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Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV‑1
Fader, Lee D, Malenfant, Eric, Parisien, Mathieu, Carson, Rebekah, Bilodeau, François, Landry, Serge, Pesant, Marc, Brochu, Christian, Morin, Sébastien, Chabot, Catherine, Halmos, Ted, Bousquet, Yves, Bailey, Murray D, Kawai, Stephen H, Coulombe, René, LaPlante, Steven, Jakalian, Araz, Bhardwaj, Punit K, Wernic, Dominik, Schroeder, Patricia, Amad, Ma’an, Edwards, Paul, Garneau, Michel, Duan, Jianmin, Cordingley, Michael, Bethell, Richard, Mason, Stephen W, Bös, Michael, Bonneau, Pierre, Poupart, Marc-André, Faucher, Anne-Marie, Simoneau, Bruno, Fenwick, Craig, Yoakim, Christiane, Tsantrizos, Youla
Published in ACS medicinal chemistry letters (10.04.2014)
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Novel pyridone EP4 agonists featuring allylic alcohol ω-chains
Dorich, Stéphane, Cox, Jennifer H., Burch, Jason D., Chagnon, Félix, Chen, Bin, Léger, Serge, St-Onge, Miguel, Fader, Lee D.
Published in Bioorganic & medicinal chemistry letters (15.05.2020)
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Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein
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Fader, Lee D., Bethell, Richard, Bonneau, Pierre, Bös, Michael, Bousquet, Yves, Cordingley, Michael G., Coulombe, René, Deroy, Patrick, Faucher, Anne-Marie, Gagnon, Alexandre, Goudreau, Nathalie, Grand-Maître, Chantal, Guse, Ingrid, Hucke, Oliver, Kawai, Stephen H., Lacoste, Jean-Eric, Landry, Serge, Lemke, Christopher T., Malenfant, Eric, Mason, Stephen, Morin, Sébastien, O’Meara, Jeff, Simoneau, Bruno, Titolo, Steve, Yoakim, Christiane
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Optimization of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of HIV capsid assembly inhibitors 1: Addressing configurational instability through scaffold modification
Fader, Lee D., Landry, Serge, Morin, Sébastien, Kawai, Stephen H., Bousquet, Yves, Hucke, Oliver, Goudreau, Nathalie, Lemke, Christopher T., Bonneau, Pierre, Titolo, Steve, Mason, Stephen, Simoneau, Bruno
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
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Optimization of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of HIV capsid assembly inhibitors 2: Structure–activity relationships (SAR) of the C3-phenyl moiety
Fader, Lee D., Landry, Serge, Goulet, Sylvie, Morin, Sébastien, Kawai, Stephen H., Bousquet, Yves, Dion, Isabelle, Hucke, Oliver, Goudreau, Nathalie, Lemke, Christopher T., Rancourt, Jean, Bonneau, Pierre, Titolo, Steve, Amad, Ma’an, Garneau, Michel, Duan, Jianmin, Mason, Stephen, Simoneau, Bruno
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
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Aligning Potency and Pharmacokinetic Properties for Pyridine-Based NCINIs
Fader, Lee D, Bailey, Murray, Beaulieu, Eric, Bilodeau, François, Bonneau, Pierre, Bousquet, Yves, Carson, Rebekah J, Chabot, Catherine, Coulombe, René, Duan, Jianmin, Fenwick, Craig, Garneau, Michel, Halmos, Ted, Jakalian, Araz, James, Clint, Kawai, Stephen H, Landry, Serge, LaPlante, Steven R, Mason, Stephen W, Morin, Sebastien, Rioux, Nathalie, Simoneau, Bruno, Surprenant, Simon, Thavonekham, Bounkham, Thibeault, Carl, Trinh, Thao, Tsantrizos, Youla, Tsoung, Jennifer, Yoakim, Christiane, Wernic, Dominik
Published in ACS medicinal chemistry letters (11.08.2016)
Published in ACS medicinal chemistry letters (11.08.2016)
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Total Synthesis of Bafilomycin A1
Kleinbeck, Florian, Fettes, Gabriela J., Fader, Lee D., Carreira, Erick M.
Published in Chemistry : a European journal (19.03.2012)
Published in Chemistry : a European journal (19.03.2012)
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Minimizing the Contribution of Enterohepatic Recirculation to Clearance in Rat for the NCINI Class of Inhibitors of HIV
Fader, Lee D, Carson, Rebekah, Morin, Sébastien, Bilodeau, François, Chabot, Catherine, Halmos, Ted, Bailey, Murray D, Kawai, Stephen H, Coulombe, René, Laplante, Steven, Mekhssian, Kevork, Jakalian, Araz, Garneau, Michel, Duan, Jianmin, Mason, Stephen W, Simoneau, Bruno, Fenwick, Craig, Tsantrizos, Youla, Yoakim, Christiane
Published in ACS medicinal chemistry letters (12.06.2014)
Published in ACS medicinal chemistry letters (12.06.2014)
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Cover Picture: Revealing Atropisomer Axial Chirality in Drug Discovery (ChemMedChem 3/2011)
LaPlante, Steven R., Edwards, Paul J., Fader, Lee D., Jakalian, Araz, Hucke, Oliver
Published in ChemMedChem (07.03.2011)
Published in ChemMedChem (07.03.2011)
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Arylcyclopropanes: Properties, Synthesis and Use in Medicinal Chemistry
Gagnon, Alexandre, Duplessis, Martin, Fader, Lee
Published in Organic preparations and procedures international (02.02.2010)
Published in Organic preparations and procedures international (02.02.2010)
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