Defining the epitope of a blood–brain barrier crossing single domain antibody specific for the type 1 insulin-like growth factor receptor
Sheff, Joey, Wang, Ping, Xu, Ping, Arbour, Melanie, Masson, Luke, van Faassen, Henk, Hussack, Greg, Kemmerich, Kristin, Brunette, Eric, Stanimirovic, Danica, Hill, Jennifer J., Kelly, John, Ni, Feng
Published in Scientific reports (19.02.2021)
Published in Scientific reports (19.02.2021)
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Epitope mapping of a blood-brain barrier crossing antibody targeting the cysteine-rich region of IGF1R using hydrogen-exchange mass spectrometry enabled by electrochemical reduction
Sheff, Joey, Kelly, John, Foss, Mary, Brunette, Eric, Kemmerich, Kristin, van Faassen, Henk, Raphael, Shalini, Hussack, Greg, Comamala, Gerard, Rand, Kasper, Stanimirovic, Danica B
Published in Journal of biochemistry (Tokyo) (01.02.2023)
Published in Journal of biochemistry (Tokyo) (01.02.2023)
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Journal Article
Neutralization of Clostridium difficile Toxin A with Single-domain Antibodies Targeting the Cell Receptor Binding Domain
Hussack, Greg, Arbabi-Ghahroudi, Mehdi, van Faassen, Henk, Songer, J. Glenn, Ng, Kenneth K.-S., MacKenzie, Roger, Tanha, Jamshid
Published in The Journal of biological chemistry (18.03.2011)
Published in The Journal of biological chemistry (18.03.2011)
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Camelid single-domain antibodies raised by DNA immunization are potent inhibitors of EGFR signaling
Rossotti, Martin A, Henry, Kevin A, van Faassen, Henk, Tanha, Jamshid, Callaghan, Deborah, Hussack, Greg, Arbabi-Ghahroudi, Mehdi, MacKenzie, C Roger
Published in Biochemical journal (07.01.2019)
Published in Biochemical journal (07.01.2019)
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Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[β1→4]GlcNAc), by Wisteria floribunda Agglutinin
Haji-Ghassemi, Omid, Gilbert, Michel, Spence, Jenifer, Schur, Melissa J., Parker, Matthew J., Jenkins, Meredith L., Burke, John E., van Faassen, Henk, Young, N. Martin, Evans, Stephen V.
Published in The Journal of biological chemistry (11.11.2016)
Published in The Journal of biological chemistry (11.11.2016)
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Multiple Mechanisms Compensate to Enhance Tumor-Protective CD8+ T Cell Response in the Long-Term Despite Poor CD8+ T Cell Priming Initially: Comparison Between an Acute Versus a Chronic Intracellular Bacterium Expressing a Model Antigen
Dudani, Renu, Chapdelaine, Yvan, Faassen, Henk van, Smith, Dean K, Shen, Hao, Krishnan, Lakshmi, Sad, Subash
Published in The Journal of immunology (1950) (01.06.2002)
Published in The Journal of immunology (1950) (01.06.2002)
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Targeting surface-layer proteins with single-domain antibodies: a potential therapeutic approach against Clostridium difficile-associated disease
Kandalaft, Hiba, Hussack, Greg, Aubry, Annie, van Faassen, Henk, Guan, Yonghong, Arbabi-Ghahroudi, Mehdi, MacKenzie, Roger, Logan, Susan M, Tanha, Jamshid
Published in Applied microbiology and biotechnology (01.10.2015)
Published in Applied microbiology and biotechnology (01.10.2015)
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Journal Article
Brain Delivery of IGF1R5, a Single-Domain Antibody Targeting Insulin-like Growth Factor-1 Receptor
Yogi, Alvaro, Hussack, Greg, van Faassen, Henk, Haqqani, Arsalan S., Delaney, Christie E., Brunette, Eric, Sandhu, Jagdeep K., Hewitt, Melissa, Sulea, Traian, Kemmerich, Kristin, Stanimirovic, Danica B.
Published in Pharmaceutics (12.07.2022)
Published in Pharmaceutics (12.07.2022)
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Corrigendum: Structure-guided design of a potent Clostridioides difficile toxin A inhibitor
Hussack, Greg, Rossotti, Martin A, van Faassen, Henk, Murase, Tomohiko, Eugenio, Luiz, Schrag, Joseph D, Ng, Kenneth K-S, Tanha, Jamshid
Published in Frontiers in microbiology (30.03.2023)
Published in Frontiers in microbiology (30.03.2023)
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Journal Article
Structure-guided design of a potent Clostridioides difficile toxin A inhibitor
Hussack, Greg, Rossotti, Martin A., van Faassen, Henk, Murase, Tomohiko, Eugenio, Luiz, Schrag, Joseph D., Ng, Kenneth K.-S., Tanha, Jamshid
Published in Frontiers in microbiology (26.01.2023)
Published in Frontiers in microbiology (26.01.2023)
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Llama peripheral B-cell populations producing conventional and heavy chain-only IgG subtypes are phenotypically indistinguishable but immunogenetically distinct
Henry, Kevin A., van Faassen, Henk, Harcus, Doreen, Marcil, Anne, Hill, Jennifer J., Muyldermans, Serge, MacKenzie, C. Roger
Published in Immunogenetics (New York) (01.04.2019)
Published in Immunogenetics (New York) (01.04.2019)
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Pentavalent single-domain antibodies reduce Campylobacter jejuni motility and colonization in chickens
Riazi, Ali, Strong, Philippa C R, Coleman, Russell, Chen, Wangxue, Hirama, Tomoko, van Faassen, Henk, Henry, Matthew, Logan, Susan M, Szymanski, Christine M, Mackenzie, Roger, Ghahroudi, Mehdi Arbabi
Published in PloS one (31.12.2013)
Published in PloS one (31.12.2013)
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Modulating antibody-dependent cellular cytotoxicity of epidermal growth factor receptor-specific heavy-chain antibodies through hinge engineering
D'Eall, Calvin, Pon, Robert A, Rossotti, Martin A, Krahn, Natalie, Spearman, Maureen, Callaghan, Deborah, van Faassen, Henk, Hussack, Greg, Stetefeld, Jörg, Butler, Michael, Durocher, Yves, Zhang, Jianbing, Henry, Kevin A, Tanha, Jamshid
Published in Immunology and cell biology (01.07.2019)
Published in Immunology and cell biology (01.07.2019)
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Monoclonal antibodies recognizing the surface autolysin IspC of Listeria monocytogenes serotype 4b: epitope localization, kinetic characterization, and cross-reaction studies
Ronholm, Jennifer, van Faassen, Henk, MacKenzie, Roger, Zhang, Zhiyi, Cao, Xudong, Lin, Min
Published in PloS one (04.02.2013)
Published in PloS one (04.02.2013)
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Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models
Rossotti, Martin A., van Faassen, Henk, Tran, Anh T., Sheff, Joey, Sandhu, Jagdeep K., Duque, Diana, Hewitt, Melissa, Wen, Xiaoxue, Bavananthasivam, Jegarubee, Beitari, Saina, Matte, Kevin, Laroche, Geneviève, Giguère, Patrick M., Gervais, Christian, Stuible, Matthew, Guimond, Julie, Perret, Sylvie, Hussack, Greg, Langlois, Marc-André, Durocher, Yves, Tanha, Jamshid
Published in Communications biology (09.09.2022)
Published in Communications biology (09.09.2022)
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Hydrogen-deuterium exchange mass spectrometry reveals three unique binding responses of mAbs directed to the catalytic domain of hCAIX
Sheff, Joey G, Kelly, John F, Robotham, Anna, Sulea, Traian, Malenfant, Félix, L'Abbé, Denis, Duchesne, Mélanie, Pelletier, Alex, Lefebvre, Jean, Acel, Andrea, Parat, Marie, Gosselin, Mylene, Wu, Cunle, Fortin, Yves, Baardsnes, Jason, Van Faassen, Henk, Awrey, Shannon, Chafe, Shawn C, McDonald, Paul C, Dedhar, Shoukat, Lenferink, Anne E G
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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A Novel Affinity Tag, ABTAG, and Its Application to the Affinity Screening of Single-Domain Antibodies Selected by Phage Display
Hussack, Greg, Baral, Toya Nath, Baardsnes, Jason, van Faassen, Henk, Raphael, Shalini, Henry, Kevin A, Zhang, Jianbing, MacKenzie, C Roger
Published in Frontiers in immunology (30.10.2017)
Published in Frontiers in immunology (30.10.2017)
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