Structure–Activity Relationships of 6-Nitroquinazolines: Dual-Acting Compounds with Inhibitory Activities toward both TNF-α Production and T Cell Proliferation
Tobe, Masanori, Isobe, Yoshiaki, Tomizawa, Hideyuki, Nagasaki, Takahiro, Obara, Fumihiro, Matsumoto, Mitsuhiro, Hayashi, Hideya
Published in Chemical & pharmaceutical bulletin (01.08.2002)
Published in Chemical & pharmaceutical bulletin (01.08.2002)
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Journal Article
Synthesis and Activity of a Metabolite of (S)-6-Amino-5-(6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamido)-3-methyl-1-phenyl-2,4-(1H,3H)-pyrimidinedione (CX-659S)
Isobe, Yoshiaki, Tobe, Masanori, Takahashi, Osamu, Goto, Yuso, Inoue, Yoshifumi, Obara, Fumihiro, Tsuchiya, Masami, Hayashi, Hideya
Published in Chemical & pharmaceutical bulletin (01.10.2002)
Published in Chemical & pharmaceutical bulletin (01.10.2002)
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Journal Article
Structure–Activity relationships of 6-fluoroquinazolines: dual-Acting compounds with inhibitory activities toward both TNF-α production and T cell proliferation
Tobe, Masanori, Isobe, Yoshiaki, Tomizawa, Hideyuki, Nagasaki, Takahiro, Obara, Fumihiro, Hayashi, Hideya
Published in Bioorganic & medicinal chemistry (20.02.2003)
Published in Bioorganic & medicinal chemistry (20.02.2003)
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Journal Article
Synthesis and biological evaluation of CX-659S and its related compounds for their inhibitory effects on the delayed-type hypersensitivity reaction
TOBE, M, ISOBE, Y, GOTO, Y, OBARA, F, TSUCHIYA, M, MATSUI, J, HIROTA, K, HAYASHI, H
Published in Bioorganic & medicinal chemistry (01.08.2000)
Published in Bioorganic & medicinal chemistry (01.08.2000)
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Journal Article
Structure–activity relationships of quinazoline derivatives: dual-acting compounds with inhibitory activities toward both TNF-α production and T Cell proliferation
Tobe, Masanori, Isobe, Yoshiaki, Tomizawa, Hideyuki, Matsumoto, Mitsuhiro, Obara, Fumihiro, Nagasaki, Takahiro, Hayashi, Hideya
Published in Bioorganic & medicinal chemistry letters (26.02.2001)
Published in Bioorganic & medicinal chemistry letters (26.02.2001)
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Journal Article
Structure-Activity Relationships of 6-Nitroquinazolines
Tobe, Masanori, Isobe, Yoshiaki, Tomizawa, Hideyuki, Nagasaki, Takahiro, Obara, Fumihiro, Matsumoto, Mitsuhiro, Hayashi, Hideya
Published in Chemical & pharmaceutical bulletin (01.08.2002)
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Published in Chemical & pharmaceutical bulletin (01.08.2002)
Journal Article
Synthesis and activity of a metabolite of (S)-6-amino-5-(6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamido)-3-methyl-1-ph enyl-2,4-(1H, 3H)-pyrimidinedione (CX-659S)
ISOBE, Yoshiaki, TOBE, Masanori, TAKAHASHI, Osamu, GOTO, Yuso, INOUE, Yoshifumi, OBARA, Fumihiro, TSUCHIYA, Masami, HAYASHI, Hideya
Published in Chemical & pharmaceutical bulletin (2002)
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Published in Chemical & pharmaceutical bulletin (2002)
Journal Article
Inhibitory Activities of Novel Pyrimidine Derivatives on the Contact Hypersensitivity Reaction
Isobe, Yoshiaki, Tobe, Masanori, Inoue, Yoshifumi, Goto, Yuso, Obara, Fumihiro, Isobe, Masakazu, Hayashi, Hideya
Published in ChemInform (19.08.2003)
Published in ChemInform (19.08.2003)
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Journal Article
Synthesis and Activity of a Metabolite of (S)-6-Amino-5- (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamido) -3-methyl-1-phenyl-2,4-(1H,3H)-pyrimidinedione (CX-659S)
Isobe, Yoshiaki, Tobe, Masanori, Takahashi, Osamu, Goto, Yuso, Inoue, Yoshifumi, Obara, Fumihiro, Tsuchiya, Masami, Hayashi, Hideya
Published in ChemInform (01.04.2003)
Published in ChemInform (01.04.2003)
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Journal Article
Structure-Activity Relationships of 6-Nitroquinazolines: Dual-Acting Compounds with Inhibitory Activities Toward both TNF-α Production and T Cell Proliferation
Tobe, Masanori, Isobe, Yoshiaki, Tomizawa, Hideyuki, Nagasaki, Takahiro, Obara, Fumihiro, Matsumoto, Mitsuhiro, Hayashi, Hideya
Published in ChemInform (21.01.2003)
Published in ChemInform (21.01.2003)
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Journal Article
Novel quinazoline derivatives
MITSUHIRO MATSUMOTO, TAKAHIRO NAGASAKI, MASANORI TOBE, FUMIHIRO OBARA, HIDEYUKI TOMIZAWA, YOSHIAKI ISOBE
Year of Publication 10.07.2003
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Year of Publication 10.07.2003
Patent
NOVEL QUINAZOLINE DERIVATIVES
NAGASAKI, TAKAHIRO, TOBE, MASANORI, OBARA, FUMIHIRO, ISOBE, YOSHIAKI, MATSUMOTO, MITSUHIRO, TOMIZAWA, HIDEYUKI
Year of Publication 09.04.2003
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Year of Publication 09.04.2003
Patent
NOVEL QUINAZOLINE DERIVATIVES
NAGASAKI, TAKAHIRO, TOBE, MASANORI, OBARA, FUMIHIRO, ISOBE, YOSHIAKI, MATSUMOTO, MITSUHIRO, TOMIZAWA, HIDEYUKI
Year of Publication 07.08.2002
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Year of Publication 07.08.2002
Patent
Novel quinazoline derivatives
MITSUHIRO MATSUMOTO, TAKAHIRO NAGASAKI, MASANORI TOBE, FUMIHIRO OBARA, HIDEYUKI TOMIZAWA, YOSHIAKI ISOBE
Year of Publication 10.05.2001
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Year of Publication 10.05.2001
Patent
NOVEL QUINAZOLINE DERIVATIVES
NAGASAKI, TAKAHIRO, TOBE, MASANORI, OBARA, FUMIHIRO, ISOBE, YOSHIAKI, MATSUMOTO, MITSUHIRO, TOMIZAWA, HIDEYUKI
Year of Publication 12.04.2001
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Year of Publication 12.04.2001
Patent