Biallelic loss of BCMA as a resistance mechanism to CAR T cell therapy in a patient with multiple myeloma
Samur, Mehmet Kemal, Fulciniti, Mariateresa, Aktas Samur, Anil, Bazarbachi, Abdul Hamid, Tai, Yu-Tzu, Prabhala, Rao, Alonso, Alejandro, Sperling, Adam S., Campbell, Timothy, Petrocca, Fabio, Hege, Kristen, Kaiser, Shari, Loiseau, Hervé Avet, Anderson, Kenneth C., Munshi, Nikhil C.
Published in Nature communications (08.02.2021)
Published in Nature communications (08.02.2021)
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Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
Walker, Brian A., Mavrommatis, Konstantinos, Wardell, Christopher P., Ashby, T. Cody, Bauer, Michael, Davies, Faith E., Rosenthal, Adam, Wang, Hongwei, Qu, Pingping, Hoering, Antje, Samur, Mehmet, Towfic, Fadi, Ortiz, Maria, Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan, Obenauer, John, Trotter, Matthew, Auclair, Daniel, Keats, Jonathan, Bolli, Niccolo, Fulciniti, Mariateresa, Szalat, Raphael, Moreau, Philippe, Durie, Brian, Stewart, A. Keith, Goldschmidt, Hartmut, Raab, Marc S., Einsele, Hermann, Sonneveld, Pieter, San Miguel, Jesus, Lonial, Sagar, Jackson, Graham H., Anderson, Kenneth C., Avet-Loiseau, Herve, Munshi, Nikhil, Thakurta, Anjan, Morgan, Gareth J.
Published in Blood (09.08.2018)
Published in Blood (09.08.2018)
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A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
Walker, Brian A., Mavrommatis, Konstantinos, Wardell, Christopher P., Ashby, T. Cody, Bauer, Michael, Davies, Faith, Rosenthal, Adam, Wang, Hongwei, Qu, Pingping, Hoering, Antje, Samur, Mehmet, Towfic, Fadi, Ortiz, Maria, Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan, Obenauer, John, Trotter, Matthew, Auclair, Daniel, Keats, Jonathan, Bolli, Niccolo, Fulciniti, Mariateresa, Szalat, Raphael, Moreau, Phillipe, Durie, Brian, Stewart, A. Keith, Goldschmidt, Hartmut, Raab, Marc S., Einsele, Hermann, Sonneveld, Pieter, San Miguel, Jesus, Lonial, Sagar, Jackson, Graham H., Anderson, Kenneth C., Avet-Loiseau, Herve, Munshi, Nikhil, Thakurta, Anjan, Morgan, Gareth
Published in Leukemia (01.01.2019)
Published in Leukemia (01.01.2019)
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Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity
Amodio, Nicola, Stamato, Maria Angelica, Juli, Giada, Morelli, Eugenio, Fulciniti, Mariateresa, Manzoni, Martina, Taiana, Elisa, Agnelli, Luca, Cantafio, Maria Eugenia Gallo, Romeo, Enrica, Raimondi, Lavinia, Caracciolo, Daniele, Zuccalà, Valeria, Rossi, Marco, Neri, Antonino, Munshi, Nikhil C., Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Published in Leukemia (01.09.2018)
Published in Leukemia (01.09.2018)
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Journal Article
Genomic landscape and chronological reconstruction of driver events in multiple myeloma
Maura, Francesco, Bolli, Niccoló, Angelopoulos, Nicos, Dawson, Kevin J., Leongamornlert, Daniel, Martincorena, Inigo, Mitchell, Thomas J., Fullam, Anthony, Gonzalez, Santiago, Szalat, Raphael, Abascal, Federico, Rodriguez-Martin, Bernardo, Samur, Mehmet Kemal, Glodzik, Dominik, Roncador, Marco, Fulciniti, Mariateresa, Tai, Yu Tzu, Minvielle, Stephane, Magrangeas, Florence, Moreau, Philippe, Corradini, Paolo, Anderson, Kenneth C., Tubio, Jose M. C., Wedge, David C., Gerstung, Moritz, Avet-Loiseau, Hervé, Munshi, Nikhil, Campbell, Peter J.
Published in Nature communications (23.08.2019)
Published in Nature communications (23.08.2019)
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Journal Article
Genomic patterns of progression in smoldering multiple myeloma
Bolli, Niccolò, Maura, Francesco, Minvielle, Stephane, Gloznik, Dominik, Szalat, Raphael, Fullam, Anthony, Martincorena, Inigo, Dawson, Kevin J., Samur, Mehmet Kemal, Zamora, Jorge, Tarpey, Patrick, Davies, Helen, Fulciniti, Mariateresa, Shammas, Masood A., Tai, Yu Tzu, Magrangeas, Florence, Moreau, Philippe, Corradini, Paolo, Anderson, Kenneth, Alexandrov, Ludmil, Wedge, David C., Avet-Loiseau, Herve, Campbell, Peter, Munshi, Nikhil
Published in Nature communications (22.08.2018)
Published in Nature communications (22.08.2018)
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Journal Article
Widespread intronic polyadenylation diversifies immune cell transcriptomes
Singh, Irtisha, Lee, Shih-Han, Sperling, Adam S., Samur, Mehmet K., Tai, Yu-Tzu, Fulciniti, Mariateresa, Munshi, Nikhil C., Mayr, Christine, Leslie, Christina S.
Published in Nature communications (30.04.2018)
Published in Nature communications (30.04.2018)
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Journal Article
Unlocking the therapeutic potential of selective CDK7 and BRD4 Inhibition against multiple myeloma cell growth
Yao, Yao, Deng, Shuhui, Ng, Jessica Fong, Yuan, Mei, Chakraborty, Chandraditya, JoyWeiler, Vera, Munshi, Nikhil, Fulciniti, Mariateresa
Published in Haematologica (Roma) (25.07.2024)
Published in Haematologica (Roma) (25.07.2024)
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Journal Article
Genome-Wide Somatic Alterations in Multiple Myeloma Reveal a Superior Outcome Group
Samur, Mehmet Kemal, Aktas Samur, Anil, Fulciniti, Mariateresa, Szalat, Raphael, Han, Tessa, Shammas, Masood, Richardson, Paul, Magrangeas, Florence, Minvielle, Stephane, Corre, Jill, Moreau, Philippe, Thakurta, Anjan, Anderson, Kenneth C, Parmigiani, Giovanni, Avet-Loiseau, Hervé, Munshi, Nikhil C
Published in Journal of clinical oncology (20.09.2020)
Published in Journal of clinical oncology (20.09.2020)
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Journal Article
Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells
Cea, Michele, Cagnetta, Antonia, Adamia, Sophia, Acharya, Chirag, Tai, Yu-Tzu, Fulciniti, Mariateresa, Ohguchi, Hiroto, Munshi, Aditya, Acharya, Prakrati, Bhasin, Manoj K., Zhong, Lei, Carrasco, Ruben, Monacelli, Fiammetta, Ballestrero, Alberto, Richardson, Paul, Gobbi, Marco, Lemoli, Roberto M., Munshi, Nikhil, Hideshima, Teru, Nencioni, Alessio, Chauhan, Dharminder, Anderson, Kenneth C.
Published in Blood (03.03.2016)
Published in Blood (03.03.2016)
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Journal Article
Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes
Binder, Moritz, Szalat, Raphael E., Talluri, Srikanth, Fulciniti, Mariateresa, Avet-Loiseau, Hervé, Parmigiani, Giovanni, Samur, Mehmet K., Munshi, Nikhil C.
Published in Nature communications (16.05.2024)
Published in Nature communications (16.05.2024)
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Journal Article
Elevated IL-17 produced by Th17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma
Prabhala, Rao H., Pelluru, Dheeraj, Fulciniti, Mariateresa, Prabhala, Harsha K., Nanjappa, Puru, Song, Weihua, Pai, Christine, Amin, Samir, Tai, Yu-Tzu, Richardson, Paul G., Ghobrial, Irene M., Treon, Steven P., Daley, John F., Anderson, Kenneth C., Kutok, Jeffery L., Munshi, Nikhil C.
Published in Blood (01.07.2010)
Published in Blood (01.07.2010)
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Journal Article
Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma
Fulciniti, Mariateresa, Tassone, Pierfrancesco, Hideshima, Teru, Vallet, Sonia, Nanjappa, Puru, Ettenberg, Seth A., Shen, Zhenxin, Patel, Nipun, Tai, Yu-tzu, Chauhan, Dharminder, Mitsiades, Constantine, Prabhala, Rao, Raje, Noopur, Anderson, Kenneth C., Stover, David R., Munshi, Nikhil C.
Published in Blood (09.07.2009)
Published in Blood (09.07.2009)
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Journal Article
Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation
Cetin, Arif E., Stevens, Mark M., Calistri, Nicholas L., Fulciniti, Mariateresa, Olcum, Selim, Kimmerling, Robert J., Munshi, Nikhil C., Manalis, Scott R.
Published in Nature communications (20.11.2017)
Published in Nature communications (20.11.2017)
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Journal Article
Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs
Sperling, Adam S., Burgess, Michael, Keshishian, Hasmik, Gasser, Jessica A., Bhatt, Shruti, Jan, Max, Słabicki, Mikołaj, Sellar, Rob S., Fink, Emma C., Miller, Peter G., Liddicoat, Brian J., Sievers, Quinlan L., Sharma, Rohan, Adams, Dylan N., Olesinski, Elyse A., Fulciniti, Mariateresa, Udeshi, Namrata D., Kuhn, Eric, Letai, Anthony, Munshi, Nikhil C., Carr, Steven A., Ebert, Benjamin L.
Published in Blood (11.07.2019)
Published in Blood (11.07.2019)
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Journal Article
Long intergenic non-coding RNAs have an independent impact on survival in multiple myeloma
Samur, Mehmet Kemal, Minvielle, Stephane, Gulla, Annamaria, Fulciniti, Mariateresa, Cleynen, Alice, Aktas Samur, Anil, Szalat, Raphael, Shammas, Masood, Magrangeas, Florence, Tai, Yu-Tzu, Auclair, Daniel, Keats, Jonathan, Richardson, Paul, Attal, Michel, Moreau, Philippe, Anderson, Kenneth C., Parmigiani, Giovanni, Avet-Loiseau, Hervé, Munshi, Nikhil C.
Published in Leukemia (01.12.2018)
Published in Leukemia (01.12.2018)
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Journal Article
Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma
Tai, Yu-Tzu, Chang, Betty Y., Kong, Sun-Young, Fulciniti, Mariateresa, Yang, Guang, Calle, Yolanda, Hu, Yiguo, Lin, Jianhong, Zhao, Jian-Jun, Cagnetta, Antonia, Cea, Michele, Sellitto, Michael A., Zhong, Mike Y., Wang, Qiuju, Acharya, Chirag, Carrasco, Daniel R., Buggy, Joseph J., Elias, Laurence, Treon, Steven P., Matsui, William, Richardson, Paul, Munshi, Nikhil C., Anderson, Kenneth C.
Published in Blood (30.08.2012)
Published in Blood (30.08.2012)
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Journal Article
Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition
Cea, Michele, Cagnetta, Antonia, Fulciniti, Mariateresa, Tai, Yu-Tzu, Hideshima, Teru, Chauhan, Dharminder, Roccaro, Aldo, Sacco, Antonio, Calimeri, Teresa, Cottini, Francesca, Jakubikova, Jana, Kong, Sun-Young, Patrone, Franco, Nencioni, Alessio, Gobbi, Marco, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth C.
Published in Blood (25.10.2012)
Published in Blood (25.10.2012)
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Journal Article
BCMA-targeted bortezomib nanotherapy improves therapeutic efficacy, overcomes resistance, and modulates the immune microenvironment in multiple myeloma
Dutta, Debasmita, Liu, Jiye, Wen, Kenneth, Kurata, Keiji, Fulciniti, Mariateresa, Gulla, Annamaria, Hideshima, Teru, Anderson, Kenneth C.
Published in Blood cancer journal (New York) (11.12.2023)
Published in Blood cancer journal (New York) (11.12.2023)
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Journal Article
The Cyclophilin A–CD147 complex promotes the proliferation and homing of multiple myeloma cells
Zhu, Di, Wang, Zhongqiu, Zhao, Jian-Jun, Calimeri, Teresa, Meng, Jiang, Hideshima, Teru, Fulciniti, Mariateresa, Kang, Yue, Ficarro, Scott B, Tai, Yu-Tzu, Hunter, Zachary, McMilin, Douglas, Tong, Haoxuan, Mitsiades, Constantine S, Wu, Catherine J, Treon, Steven P, Dorfman, David M, Pinkus, Geraldine, Munshi, Nikhil C, Tassone, Pierfrancesco, Marto, Jarrod A, Anderson, Kenneth C, Carrasco, Ruben D
Published in Nature medicine (01.06.2015)
Published in Nature medicine (01.06.2015)
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