TAS-114, a First-in-Class Dual dUTPase/DPD Inhibitor, Demonstrates Potential to Improve Therapeutic Efficacy of Fluoropyrimidine-Based Chemotherapy
Yano, Wakako, Yokogawa, Tatsushi, Wakasa, Takeshi, Yamamura, Keisuke, Fujioka, Akio, Yoshisue, Kunihiro, Matsushima, Eiji, Miyahara, Seiji, Miyakoshi, Hitoshi, Taguchi, Junko, Chong, Khoon Tee, Takao, Yayoi, Fukuoka, Masayoshi, Matsuo, Kenichi
Published in Molecular cancer therapeutics (01.08.2018)
Published in Molecular cancer therapeutics (01.08.2018)
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dUTPase inhibition confers susceptibility to a thymidylate synthase inhibitor in DNA‐repair‐defective human cancer cells
Yokogawa, Tatsushi, Yano, Wakako, Tsukioka, Sayaka, Osada, Akiko, Wakasa, Takeshi, Ueno, Hiroyuki, Hoshino, Takuya, Yamamura, Keisuke, Fujioka, Akio, Fukuoka, Masayoshi, Ohkubo, Shuichi, Matsuo, Kenichi
Published in Cancer science (01.01.2021)
Published in Cancer science (01.01.2021)
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Discovery of a Novel Class of Potent Human Deoxyuridine Triphosphatase Inhibitors Remarkably Enhancing the Antitumor Activity of Thymidylate Synthase Inhibitors
Miyahara, Seiji, Miyakoshi, Hitoshi, Yokogawa, Tatsushi, Chong, Khoon Tee, Taguchi, Junko, Muto, Toshiharu, Endoh, Kanji, Yano, Wakako, Wakasa, Takeshi, Ueno, Hiroyuki, Takao, Yayoi, Fujioka, Akio, Hashimoto, Akihiro, Itou, Kenjirou, Yamamura, Keisuke, Nomura, Makoto, Nagasawa, Hideko, Shuto, Satoshi, Fukuoka, Masayoshi
Published in Journal of medicinal chemistry (12.04.2012)
Published in Journal of medicinal chemistry (12.04.2012)
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Discovery of Highly Potent Human Deoxyuridine Triphosphatase Inhibitors Based on the Conformation Restriction Strategy
Miyahara, Seiji, Miyakoshi, Hitoshi, Yokogawa, Tatsushi, Chong, Khoon Tee, Taguchi, Junko, Muto, Toshiharu, Endoh, Kanji, Yano, Wakako, Wakasa, Takeshi, Ueno, Hiroyuki, Takao, Yayoi, Fujioka, Akio, Hashimoto, Akihiro, Itou, Kenjirou, Yamamura, Keisuke, Nomura, Makoto, Nagasawa, Hideko, Shuto, Satoshi, Fukuoka, Masayoshi
Published in Journal of medicinal chemistry (14.06.2012)
Published in Journal of medicinal chemistry (14.06.2012)
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Synthesis and Discovery of N-Carbonylpyrrolidine- or N-Sulfonylpyrrolidine-Containing Uracil Derivatives as Potent Human Deoxyuridine Triphosphatase Inhibitors
Miyakoshi, Hitoshi, Miyahara, Seiji, Yokogawa, Tatsushi, Chong, Khoon Tee, Taguchi, Junko, Endoh, Kanji, Yano, Wakako, Wakasa, Takeshi, Ueno, Hiroyuki, Takao, Yayoi, Nomura, Makoto, Shuto, Satoshi, Nagasawa, Hideko, Fukuoka, Masayoshi
Published in Journal of medicinal chemistry (12.04.2012)
Published in Journal of medicinal chemistry (12.04.2012)
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Abstract B89: Expression of DNA damage repair enzymes determine the efficacy of a novel dUTPase inhibitor, TAS-114
Tsukioka, Sayaka, Yano, Wakako, Yokogawa, Tatsushi, Wakasa, Takeshi, Fujioka, Akio, Yamamura, Keisuke, Itoh, Satoko, Fukuoka, Masayoshi, Matsuo, Kenichi, Noguchi, Kazuharu, Utsugi, Teruhiro
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Recovery of Oculomotor Nerve Palsy After Surgical and Endovascular Repair of Unruptured Internal Carotid-Posterior Communicating Artery Aneurysms
Tabata, Shinya, Take, Yushiro, Kimura, Tatsuki, Onodera, Koki, Kume, Haruka, Fukuoka, Masayoshi, Suzuki, Kaima, Ooigawa, Hidetoshi, Kohyama, Shinya, Kurita, Hiroki
Published in World neurosurgery (01.08.2024)
Published in World neurosurgery (01.08.2024)
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Double-hit primary central nervous system lymphoma with histogenetically proven bone marrow infiltration: a case report and a review of the literature
Onodera, Koki, Shirahata, Mitsuaki, Mizuno, Reina, Fukuoka, Masayoshi, Suzuki, Tomonari, Satoh, Tsugumi, Homma, Taku, Takahashi, Naoki, Mishima, Kazuhiko
Published in Brain tumor pathology (01.10.2024)
Published in Brain tumor pathology (01.10.2024)
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An Efficient Synthesis of Cyclic IDP- and Cyclic 8-Bromo-IDP-Carbocyclic-Riboses Using a Modified Hata Condensation Method To Form an Intramolecular Pyrophosphate Linkage as a Key Step. An Entry to a General Method for the Chemical Synthesis of Cyclic ADP-Ribose Analogues1
Fukuoka, Masayoshi, Shuto, Satoshi, Minakawa, Noriaki, Ueno, Yoshihito, Matsuda, Akira
Published in Journal of organic chemistry (25.08.2000)
Published in Journal of organic chemistry (25.08.2000)
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Cytopathological and histopathological features of cerebral granular cell astrocytoma: A case report
Homma, Taku, Izu, Asami, Adachi, Jun‐ichi, Fukuoka, Masayoshi, Nishikawa, Ryo
Published in Cytopathology (Oxford) (01.01.2022)
Published in Cytopathology (Oxford) (01.01.2022)
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Total Synthesis of Cyclic ADP-carbocyclic-ribose, a Stable Mimic of Ca2+-Mobilizing Second Messenger Cyclic ADP-Ribose1
Shuto, Satoshi, Fukuoka, Masayoshi, Manikowsky, Andrzej, Ueno, Yoshihito, Nakano, Takashi, Kuroda, Ritsu, Kuroda, Hideyo, Matsuda, Akira
Published in Journal of the American Chemical Society (12.09.2001)
Published in Journal of the American Chemical Society (12.09.2001)
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Alternative synthesis of cyclic IDP-carbocyclic ribose. Efficient cyclization of an 8-bromo-N1-[5-(phosphoryl)carbocyclic-ribosyl]inosine 5′-phenylthiophosphate derivative mediated by iodine
Fukuoka, Masayoshi, Shuto, Satoshi, Minakawa, Noriaki, Ueno, Yoshihito, Matsuda, Akira
Published in Tetrahedron letters (01.07.1999)
Published in Tetrahedron letters (01.07.1999)
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Giant Meningioma with Deformation of the Head : A Case Report
Fukuoka, Masayoshi, Kaji, Masatomo, Ueda, Ryuta, Amadatsu, Toshihiro, Yamamura, Rihito, Mizukami, Shuki, Murai, An, Ueki, Wataru, Yamashiro, Shigeo
Published in Nōshinkei geka jānaru = Japanese journal of neurosurgery (2023)
Published in Nōshinkei geka jānaru = Japanese journal of neurosurgery (2023)
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1,2,3-Triazole-Containing Uracil Derivatives with Excellent Pharmacokinetics as a Novel Class of Potent Human Deoxyuridine Triphosphatase Inhibitors
Miyakoshi, Hitoshi, Miyahara, Seiji, Yokogawa, Tatsushi, Endoh, Kanji, Muto, Toshiharu, Yano, Wakako, Wakasa, Takeshi, Ueno, Hiroyuki, Chong, Khoon Tee, Taguchi, Junko, Nomura, Makoto, Takao, Yayoi, Fujioka, Akio, Hashimoto, Akihiro, Itou, Kenjirou, Yamamura, Keisuke, Shuto, Satoshi, Nagasawa, Hideko, Fukuoka, Masayoshi
Published in Journal of medicinal chemistry (26.07.2012)
Published in Journal of medicinal chemistry (26.07.2012)
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