Efficacy of Oral Treatment With Tacrolimus in the Renal Transplant Model in Cynomolgus Monkeys
Kinugasa, Fumitaka, Nagatomi, Itsuo, Ishikawa, Hirofumi, Nakanishi, Tomonori, Maeda, Masashi, Hirose, Jun, Fukahori, Hidehiko, Ooshima, Shinsuke, Noto, Takahisa, Higashi, Yasuyuki, Seki, Nobuo, Mutoh, Seitaro
Published in Journal of Pharmacological Sciences (2008)
Published in Journal of Pharmacological Sciences (2008)
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In vitro pharmacological effects of peficitinib on lymphocyte activation: a potential treatment for systemic sclerosis with JAK inhibitors
Kitanaga, Yukihiro, Imamura, Emiko, Nakahara, Yutaka, Fukahori, Hidehiko, Fujii, Yasutomo, Kubo, Satoshi, Nakayamada, Shingo, Tanaka, Yoshiya
Published in Rheumatology (Oxford, England) (01.08.2020)
Published in Rheumatology (Oxford, England) (01.08.2020)
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Development of a novel Poly (I:C)-induced murine model with accelerated lupus nephritis and examination of the therapeutic effects of mycophenolate mofetil and a cathepsin S inhibitor
Kawato, Yuka, Fukahori, Hidehiko, Nakamura, Koji, Kubo, Kaori, Hiramitsu, Masaki, Kinugasa, Fumitaka, Morokata, Tatsuaki
Published in European journal of pharmacology (05.01.2023)
Published in European journal of pharmacology (05.01.2023)
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Lit-LAMP-DNA-vaccine for shrimp allergy prevents anaphylactic symptoms in a murine model
Kubo, Kaori, Takeda, Shinobu, Uchida, Masao, Maeda, Masashi, Endo, Nobuyasu, Sugahara, Shingo, Suzuki, Hiroshi, Fukahori, Hidehiko
Published in International immunopharmacology (01.12.2022)
Published in International immunopharmacology (01.12.2022)
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Potential benefit of the cathepsin S inhibitor, ASP1617, as a treatment for systemic lupus erythematosus
Kawato, Yuka, Fukahori, Hidehiko, Nakamura, Koji, Kanno, Atsuo, Kubo, Kaori, Hiramitsu, Masaki, Matsuda, Toshihiro, Hanada, Yuichi, Furukawa, Takako, Nakajima, Yutaka, Kinugasa, Fumitaka, Morokata, Tatsuaki
Published in European journal of pharmacology (15.03.2022)
Published in European journal of pharmacology (15.03.2022)
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The PI3Kδ selective inhibitor AS2541019 suppresses donor-specific antibody production in rat cardiac and non-human primate renal allotransplant models
Marui, Takanori, Fukahori, Hidehiko, Ito, Misato, Kaneko, Yoko, Maeda, Masashi, Tsujimoto, Susumu, Morokata, Tatsuaki
Published in International immunopharmacology (01.10.2019)
Published in International immunopharmacology (01.10.2019)
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Impacts of dosing and drug withdrawal period on tacrolimus-based triple therapy in a non-human primate renal transplantation model
Naganuma, Yuuki, Maeda, Masashi, Nakamura, Koji, Fukahori, Hidehiko, Satake, Hiroyuki, Murakami, Ryuji, Hanaoka, Kaori, Higashi, Yasuyuki, Koyama, Hironari, Morokata, Tatsuaki
Published in Transplant immunology (01.12.2022)
Published in Transplant immunology (01.12.2022)
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Effects of AS2819899, a novel selective PI3Kδ inhibitor, in a NZB/W F1 mouse lupus-like nephritis model
Kaneko, Yoko, Fukahori, Hidehiko, Yamagami, Kaoru, Kawashima, Tomoko, Ito, Misato, Akamatsu, Masahiko, Marui, Takanori, Kato, Koji, Takahashi, Fumie, Morokata, Tatsuaki
Published in International immunopharmacology (01.10.2020)
Published in International immunopharmacology (01.10.2020)
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Discovery and biological evaluation of novel pyrazolopyridine derivatives as potent and orally available PI3Kδ inhibitors
Hamajima, Toshihiro, Takahashi, Fumie, Kato, Koji, Mukoyoshi, Koichiro, Yoshihara, Kousei, Yamaki, Susumu, Sugano, Yukihito, Moritomo, Ayako, Yamagami, Kaoru, Yokoo, Koji, Fukahori, Hidehiko
Published in Bioorganic & medicinal chemistry (15.05.2018)
Published in Bioorganic & medicinal chemistry (15.05.2018)
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Journal Article
Effects of AS2541019, a novel selective PI3Kδ inhibitor, on antibody production and hamster to rat xenotransplantation
Marui, Takanori, Fukahori, Hidehiko, Kawashima, Tomoko, Ito, Misato, Akamatsu, Masahiko, Kaneko, Yoko, Takahashi, Fumie, Imada, Sunao, Morokata, Tatsuaki
Published in European journal of pharmacology (05.05.2018)
Published in European journal of pharmacology (05.05.2018)
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Journal Article
Optimization and in vivo evaluation of pyrazolopyridines as a potent and selective PI3Kδ inhibitor
Hamajima, Toshihiro, Takahashi, Fumie, Kato, Koji, Sugano, Yukihito, Yamaki, Susumu, Moritomo, Ayako, Kubo, Satoshi, Nakamura, Koji, Yamagami, Kaoru, Hamakawa, Nozomu, Yokoo, Koji, Fukahori, Hidehiko
Published in Bioorganic & medicinal chemistry (07.08.2018)
Published in Bioorganic & medicinal chemistry (07.08.2018)
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Journal Article
Optimization of 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidines to generate a highly selective PI3Kδ inhibitor
Hamajima, Toshihiro, Takahashi, Fumie, Kato, Koji, Sugano, Yukihito, Yamaki, Susumu, Suzuki, Daisuke, Moritomo, Ayako, Kubo, Satoshi, Nakamura, Koji, Yamagami, Kaoru, Yokoo, Koji, Fukahori, Hidehiko
Published in Bioorganic & medicinal chemistry (15.03.2019)
Published in Bioorganic & medicinal chemistry (15.03.2019)
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Journal Article
Replacement of mycophenolate mofetil with a JAK inhibitor, AS2553627, in combination with low-dose tacrolimus, for renal allograft rejection in non-human primates
Nakamura, Koji, Oshima, Shinsuke, Maeda, Masashi, Morio, Hiroki, Fukahori, Hidehiko, Nakanishi, Tomonori, Tsujimoto, Susumu, Hirose, Jun, Noto, Takahisa, Hamakawa, Nozomu, Inami, Masamichi, Morokata, Tatsuaki
Published in International immunopharmacology (01.11.2018)
Published in International immunopharmacology (01.11.2018)
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Effective suppression of donor specific antibody production by Cathepsin S inhibitors in a mouse transplantation model
Kubo, Kaori, Kawato, Yuka, Nakamura, Koji, Nakajima, Yutaka, Nakagawa, Terry Y., Hanaoka, Kaori, Oshima, Shinsuke, Fukahori, Hidehiko, Inami, Masamichi, Morokata, Tatsuaki, Higashi, Yasuyuki
Published in European journal of pharmacology (05.11.2018)
Published in European journal of pharmacology (05.11.2018)
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Journal Article
Effect of AS2521780, a novel PKCθ selective inhibitor, on T cell-mediated immunity
Fukahori, Hidehiko, Chida, Noboru, Maeda, Masashi, Tasaki, Mamoru, Kawashima, Tomoko, Matsuoka, Hideaki, Suzuki, Keiko, Ishikawa, Takeshi, Tanaka, Akira, Higashi, Yasuyuki
Published in European journal of pharmacology (15.12.2014)
Published in European journal of pharmacology (15.12.2014)
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Journal Article
Site-directed affinity-labeling of delta opioid receptors by
Isozaki, Kaname, Fukahori, Hidehiko, Honda, Takeshi, Shirasu, Naoto, Okada, Kazushi, Nose, Takeru, Sakaguchi, Kazuyasu, Shimohigashi, Yasuyuki
Published in International journal of peptide research and therapeutics (01.11.2003)
Published in International journal of peptide research and therapeutics (01.11.2003)
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Journal Article
Benefits of a loading dose of tacrolimus on graft survival of kidney transplants in nonhuman primates
Hanaoka, Kaori, Maeda, Masashi, Tsujimoto, Susumu, Oshima, Shinsuke, Fukahori, Hidehiko, Nakamura, Koji, Noto, Takahisa, Higashi, Yasuyuki, Hirose, Jun, Takakura, Shoji, Morokata, Tatsuaki
Published in Transplant immunology (01.02.2019)
Published in Transplant immunology (01.02.2019)
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Journal Article
The Effect of ASP2409, a Novel CD86-Selective Variant of CTLA4-Ig, on Renal Allograft Rejection in Nonhuman Primates
Oshima, Shinsuke, Karrer, Erik E, Kawato, Yuka, Maeda, Masashi, Fukahori, Hidehiko, Tsujimoto, Susumu, Hirose, Jun, Nakamura, Koji, Marui, Takanori, Takamura, Fujiko, Noto, Takahisa, Chapin, Steven J, Fujii, Yasutomo, Neighbors, Margaret, Viswanathan, Sridhar, Devens, Bruce H, Higashi, Yasuyuki
Published in Transplantation (01.12.2016)
Published in Transplantation (01.12.2016)
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Journal Article
Prevention of chronic renal allograft rejection by AS2553627, a novel JAK inhibitor, in a rat transplantation model
Nakamura, Koji, Kawato, Yuka, Kaneko, Yoko, Hanaoka, Kaori, Kubo, Kaori, Nakanishi, Tomonori, Maeda, Masashi, Fukahori, Hidehiko, Ito, Misato, Noto, Takahisa, Inami, Masamichi, Hirose, Jun, Morokata, Tatsuaki
Published in Transplant immunology (01.02.2018)
Published in Transplant immunology (01.02.2018)
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Journal Article
Effect of novel PKCθ selective inhibitor AS2521780 on acute rejection in rat and non-human primate models of transplantation
Fukahori, Hidehiko, Chida, Noboru, Maeda, Masashi, Tasaki, Mamoru, Kawashima, Tomoko, Noto, Takahisa, Tsujimoto, Susumu, Nakamura, Koji, Oshima, Shinsuke, Hirose, Jun, Higashi, Yasuyuki, Morokata, Tatsuaki
Published in International immunopharmacology (01.08.2015)
Published in International immunopharmacology (01.08.2015)
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