Dual Therapeutic Action of a Neutralizing Anti-FGF2 Aptamer in Bone Disease and Bone Cancer Pain
Jin, Ling, Nonaka, Yosuke, Miyakawa, Shin, Fujiwara, Masatoshi, Nakamura, Yoshikazu
Published in Molecular therapy (01.11.2016)
Published in Molecular therapy (01.11.2016)
Get full text
Journal Article
Structural basis for specific inhibition of Autotaxin by a DNA aptamer
Kato, Kazuki, Ikeda, Hisako, Miyakawa, Shin, Futakawa, Satoshi, Nonaka, Yosuke, Fujiwara, Masatoshi, Okudaira, Shinichi, Kano, Kuniyuki, Aoki, Junken, Morita, Junko, Ishitani, Ryuichiro, Nishimasu, Hiroshi, Nakamura, Yoshikazu, Nureki, Osamu
Published in Nature structural & molecular biology (01.05.2016)
Published in Nature structural & molecular biology (01.05.2016)
Get full text
Journal Article
The FGF2 aptamer inhibits the growth of FGF2-FGFR pathway driven lung cancer cells
Hamamoto, Junko, Yasuda, Hiroyuki, Nonaka, Yosuke, Fujiwara, Masatoshi, Nakamura, Yoshikazu, Soejima, Kenzo, Betsuyaku, Tomoko
Published in Biochemical and biophysical research communications (10.09.2018)
Published in Biochemical and biophysical research communications (10.09.2018)
Get full text
Journal Article
Anti-Angiogenic and Anti-Scarring Dual Action of an Anti-Fibroblast Growth Factor 2 Aptamer in Animal Models of Retinal Disease
Matsuda, Yusaku, Nonaka, Yosuke, Futakawa, Satoshi, Imai, Hirotaka, Akita, Kazumasa, Nishihata, Toshiaki, Fujiwara, Masatoshi, Ali, Yusuf, Bhisitkul, Robert B., Nakamura, Yoshikazu
Published in Molecular therapy. Nucleic acids (06.09.2019)
Published in Molecular therapy. Nucleic acids (06.09.2019)
Get full text
Journal Article
Midkine Promotes Neuroblastoma through Notch2 Signaling
KISHIDA, Satoshi, PING MU, MIYAKAWA, Shin, FUJIWARA, Masatoshi, ABE, Tomoyuki, SAKAMOTO, Kazuma, ONISHI, Akira, NAKAMURA, Yoshikazu, KADOMATSU, Kenji
Published in Cancer research (Chicago, Ill.) (15.02.2013)
Published in Cancer research (Chicago, Ill.) (15.02.2013)
Get full text
Journal Article
Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population
Wang, Jinyan, Takeuchi, Hideyuki, Sonobe, Yoshifumi, Jin, Shijie, Mizuno, Tetsuya, Miyakawa, Shin, Fujiwara, Masatoshi, Nakamura, Yoshikazu, Kato, Takuma, Muramatsu, Hisako, Muramatsu, Takashi, Suzumura, Akio
Published in Proceedings of the National Academy of Sciences - PNAS (11.03.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (11.03.2008)
Get full text
Journal Article
Inhibition of activin receptor-like kinase 5 attenuates Bleomycin-induced pulmonary fibrosis
Higashiyama, Hiroyuki, Yoshimoto, Daisuke, Kaise, Toshihiko, Matsubara, Shigeki, Fujiwara, Masatoshi, Kikkawa, Hideo, Asano, Satoshi, Kinoshita, Mine
Published in Experimental and molecular pathology (01.08.2007)
Published in Experimental and molecular pathology (01.08.2007)
Get full text
Journal Article
Human Follicular Dendritic Cells Remain Uninfected and Capture Human Immunodeficiency Virus Type 1 through CD54-CD11a Interaction
Fujiwara, M, Tsunoda, R, Shigeta, S, Yokota, T, Baba, M
Published in Journal of Virology (01.05.1999)
Published in Journal of Virology (01.05.1999)
Get full text
Journal Article
Inhibitory Effects of an Antisense Oligonucleotide in an Experimentally Infected Mouse Model of Influenza A Virus
Mizuta, Tadashi, Fujiwara, Masatoshi, Abe, Takayuki, Miyano-Kurosaki, Naoko, Yokota, Tomoyuki, Shigeta, Shiro, Takaku, Hiroshi
Published in Biochemical and biophysical research communications (09.12.2000)
Published in Biochemical and biophysical research communications (09.12.2000)
Get full text
Journal Article
An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice
Kimura, Takeshi, Bosakova, Michaela, Nonaka, Yosuke, Hruba, Eva, Yasuda, Kie, Futakawa, Satoshi, Kubota, Takuo, Fafilek, Bohumil, Gregor, Tomas, Abraham, Sara P, Gomolkova, Regina, Belaskova, Silvie, Pesl, Martin, Csukasi, Fabiana, Duran, Ivan, Fujiwara, Masatoshi, Kavkova, Michaela, Zikmund, Tomas, Kaiser, Josef, Buchtova, Marcela, Krakow, Deborah, Nakamura, Yoshikazu, Ozono, Keiichi, Krejci, Pavel
Published in Science translational medicine (05.05.2021)
Published in Science translational medicine (05.05.2021)
Get more information
Journal Article
An anti-chymase RNA aptamer improved cardiac function in experimental heart failure
Jin, Denan, Takai, Shinji, Nonaka, Yosuke, Yamazaki, Satoko, Fujiwara, Masatoshi, Nakamura, Yoshikazu
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
Get full text
Journal Article
Discovery of anti-influenza A virus activity of a corynanthe-type indole alkaloid, hirsutine, in vitro and the structure-activity relationship of natural and synthetic analogs
Takayama, Hiromitsu, Iimura, Yasuo, Kitajima, Mariko, Aimi, Norio, Konno, Kenji, Inoue, Hiroshi, Fujiwara, Masatoshi, Mizuta, Tadashi, Yokota, Tomoyuki, Shigeta, Shiro, Tokuhisa, Kenji, Hanasaki, Yasuaki, Katsuura, Kimio
Published in Bioorganic & medicinal chemistry letters (16.12.1997)
Published in Bioorganic & medicinal chemistry letters (16.12.1997)
Get full text
Journal Article