DPPC-cholesterol phase diagram using coarse-grained Molecular Dynamics simulations
Wang, Yin, Gkeka, Paraskevi, Fuchs, Julian E., Liedl, Klaus R., Cournia, Zoe
Published in Biochimica et biophysica acta (01.11.2016)
Published in Biochimica et biophysica acta (01.11.2016)
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Journal Article
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
Kofink, Christiane, Trainor, Nicole, Mair, Barbara, Wöhrle, Simon, Wurm, Melanie, Mischerikow, Nikolai, Roy, Michael J., Bader, Gerd, Greb, Peter, Garavel, Géraldine, Diers, Emelyne, McLennan, Ross, Whitworth, Claire, Vetma, Vesna, Rumpel, Klaus, Scharnweber, Maximilian, Fuchs, Julian E., Gerstberger, Thomas, Cui, Yunhai, Gremel, Gabriela, Chetta, Paolo, Hopf, Stefan, Budano, Nicole, Rinnenthal, Joerg, Gmaschitz, Gerhard, Mayer, Moriz, Koegl, Manfred, Ciulli, Alessio, Weinstabl, Harald, Farnaby, William
Published in Nature communications (10.10.2022)
Published in Nature communications (10.10.2022)
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Journal Article
Inhibition of Collagenase by Mycosporine-like Amino Acids from Marine Sources
Hartmann, Anja, Gostner, Johanna, Fuchs, Julian E., Chaita, Eliza, Aligiannis, Nektarios, Skaltsounis, Leandros, Ganzera, Markus
Published in Planta medica (01.07.2015)
Published in Planta medica (01.07.2015)
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Journal Article
The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101
Ackaert, Chloé, Kofler, Stefan, Horejs-Hoeck, Jutta, Zulehner, Nora, Asam, Claudia, von Grafenstein, Susanne, Fuchs, Julian E, Briza, Peter, Liedl, Klaus R, Bohle, Barbara, Ferreira, Fátima, Brandstetter, Hans, Oostingh, Gertie J, Duschl, Albert
Published in PloS one (15.08.2014)
Published in PloS one (15.08.2014)
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Journal Article
PI by NMR: Probing CH–π Interactions in Protein–Ligand Complexes by NMR Spectroscopy
Platzer, Gerald, Mayer, Moriz, Beier, Andreas, Brüschweiler, Sven, Fuchs, Julian E., Engelhardt, Harald, Geist, Leonhard, Bader, Gerd, Schörghuber, Julia, Lichtenecker, Roman, Wolkerstorfer, Bernhard, Kessler, Dirk, McConnell, Darryl B., Konrat, Robert
Published in Angewandte Chemie International Edition (24.08.2020)
Published in Angewandte Chemie International Edition (24.08.2020)
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Journal Article
Peptidic Macrocycles - Conformational Sampling and Thermodynamic Characterization
Kamenik, Anna S, Lessel, Uta, Fuchs, Julian E, Fox, Thomas, Liedl, Klaus R
Published in Journal of chemical information and modeling (29.05.2018)
Published in Journal of chemical information and modeling (29.05.2018)
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Journal Article
Cooperative Binding of Aflatoxin B1 by Cytochrome P450 3A4: A Computational Study
Bren, Urban, Fuchs, Julian E, Oostenbrink, Chris
Published in Chemical research in toxicology (15.12.2014)
Published in Chemical research in toxicology (15.12.2014)
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Journal Article
Start Selective and Rigidify: The Discovery Path toward a Next Generation of EGFR Tyrosine Kinase Inhibitors
Engelhardt, Harald, Böse, Dietrich, Petronczki, Mark, Scharn, Dirk, Bader, Gerd, Baum, Anke, Bergner, Andreas, Chong, Eugene, Döbel, Sandra, Egger, Georg, Engelhardt, Christian, Ettmayer, Peter, Fuchs, Julian E, Gerstberger, Thomas, Gonnella, Nina, Grimm, Andreas, Grondal, Elisabeth, Haddad, Nizar, Hopfgartner, Barbara, Kousek, Roland, Krawiec, Mariusz, Kriz, Monika, Lamarre, Lyne, Leung, Joyce, Mayer, Moriz, Patel, Nitinchandra D, Simov, Biljana Peric, Reeves, Jonathan T, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Solca, Flavio, Stadtmüller, Heinz, Tan, Zhulin, Wunberg, Tobias, Zoephel, Andreas, McConnell, Darryl B
Published in Journal of medicinal chemistry (27.11.2019)
Published in Journal of medicinal chemistry (27.11.2019)
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Journal Article
Heteroaromatic π‑Stacking Energy Landscapes
Huber, Roland G, Margreiter, Michael A, Fuchs, Julian E, von Grafenstein, Susanne, Tautermann, Christofer S, Liedl, Klaus R, Fox, Thomas
Published in Journal of chemical information and modeling (27.05.2014)
Published in Journal of chemical information and modeling (27.05.2014)
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Journal Article
Development of a Novel Azaspirane That Targets the Janus Kinase-Signal Transducer and Activator of Transcription (STAT) Pathway in Hepatocellular Carcinoma in Vitro and in Vivo
Mohan, Chakrabhavi Dhananjaya, Bharathkumar, Hanumantharayappa, Bulusu, Krishna C., Pandey, Vijay, Rangappa, Shobith, Fuchs, Julian E., Shanmugam, Muthu K., Dai, Xiaoyun, Li, Feng, Deivasigamani, Amudha, Hui, Kam M., Kumar, Alan Prem, Lobie, Peter E., Bender, Andreas, Basappa, Salundi, Sethi, Gautam, Rangappa, Kanchugarakoppal S.
Published in The Journal of biological chemistry (05.12.2014)
Published in The Journal of biological chemistry (05.12.2014)
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Journal Article
Asymmetric arginine dimethylation of RelA provides a repressive mark to modulate TNFα/NF-κB response
Reintjes, Anja, Fuchs, Julian E., Kremser, Leopold, Lindner, Herbert H., Liedl, Klaus R., Huber, Lukas A., Valovka, Taras
Published in Proceedings of the National Academy of Sciences - PNAS (19.04.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (19.04.2016)
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Journal Article
Probing Protein–Ligand Methyl−π Interaction Geometries through Chemical Shift Measurements of Selectively Labeled Methyl Groups
Beier, Andreas, Platzer, Gerald, Höfurthner, Theresa, Ptaszek, Aleksandra L., Lichtenecker, Roman J., Geist, Leonhard, Fuchs, Julian E., McConnell, Darryl B., Mayer, Moriz, Konrat, Robert
Published in Journal of medicinal chemistry (08.08.2024)
Published in Journal of medicinal chemistry (08.08.2024)
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Journal Article
Rationalizing Tight Ligand Binding through Cooperative Interaction Networks
Kuhn, Bernd, Fuchs, Julian E, Reutlinger, Michael, Stahl, Martin, Taylor, Neil R
Published in Journal of chemical information and modeling (27.12.2011)
Published in Journal of chemical information and modeling (27.12.2011)
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Journal Article
Discovery of a small-molecule inhibitor of specific serine residue BAD phosphorylation
Pandey, Vijay, Wang, Baocheng, Mohan, Chakrabhavi Dhananjaya, Raquib, Ainiah Rushdiana, Rangappa, Shobith, Srinivasa, Venkatachalaiah, Fuchs, Julian E., Girish, Kesturu S., Zhu, Tao, Bender, Andreas, Ma, Lan, Yin, Zhinan, Basappa, Rangappa, Kanchugarakoppal S., Lobie, Peter E.
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2018)
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Journal Article
Matched Molecular Pair Analysis: Significance and the Impact of Experimental Uncertainty
Kramer, Christian, Fuchs, Julian E, Whitebread, Steven, Gedeck, Peter, Liedl, Klaus R
Published in Journal of medicinal chemistry (08.05.2014)
Published in Journal of medicinal chemistry (08.05.2014)
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Journal Article
Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen
Machado, Yoan, MSc, Freier, Regina, MSc, Scheiblhofer, Sandra, PhD, Thalhamer, Theresa, PhD, Mayr, Melissa, BSc, Briza, Peter, PhD, Grutsch, Sarina, PhD, Ahammer, Linda, MSc, Fuchs, Julian E., PhD, Wallnoefer, Hannes G., PhD, Isakovic, Almedina, MSc, Kohlbauer, Vera, MSc, Hinterholzer, Arthur, BSc, Steiner, Markus, MSc, Danzer, Martin, MSc, Horejs-Hoeck, Jutta, PhD, Ferreira, Fatima, PhD, Liedl, Klaus R., PhD, Tollinger, Martin, PhD, Lackner, Peter, PhD, Johnson, Christopher M., PhD, Brandstetter, Hans, PhD, Thalhamer, Josef, PhD, Weiss, Richard, PhD
Published in Journal of allergy and clinical immunology (01.05.2016)
Published in Journal of allergy and clinical immunology (01.05.2016)
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Journal Article
Synthesis of 1,2-benzisoxazole tethered 1,2,3-triazoles that exhibit anticancer activity in acute myeloid leukemia cell lines by inhibiting histone deacetylases, and inducing p21 and tubulin acetylation
Ashwini, Nanjundaswamy, Garg, Manoj, Mohan, Chakrabhavi Dhananjaya, Fuchs, Julian E., Rangappa, Shobith, Anusha, Sebastian, Swaroop, Toreshettahally Ramesh, Rakesh, Kodagahalli S., Kanojia, Deepika, Madan, Vikas, Bender, Andreas, Koeffler, H. Phillip, Basappa, Rangappa, Kanchugarakoppal S.
Published in Bioorganic & medicinal chemistry (15.09.2015)
Published in Bioorganic & medicinal chemistry (15.09.2015)
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Journal Article
Characterizing Protease Specificity: How Many Substrates Do We Need?
Schauperl, Michael, Fuchs, Julian E, Waldner, Birgit J, Huber, Roland G, Kramer, Christian, Liedl, Klaus R
Published in PloS one (11.11.2015)
Published in PloS one (11.11.2015)
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Journal Article
Ligand Binding Modulates the Structural Dynamics and Compactness of the Major Birch Pollen Allergen
Grutsch, Sarina, Fuchs, Julian E., Freier, Regina, Kofler, Stefan, Bibi, Marium, Asam, Claudia, Wallner, Michael, Ferreira, Fátima, Brandstetter, Hans, Liedl, Klaus R., Tollinger, Martin
Published in Biophysical journal (16.12.2014)
Published in Biophysical journal (16.12.2014)
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Journal Article