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Published in The New England journal of medicine (03.08.2006)
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Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population
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A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity
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Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population
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Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations
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Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin
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Published in The Journal of biological chemistry (10.10.2003)
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genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 diabetes in the Japanese population
Horikoshi, M, Hara, K, Ito, C, Nagai, R, Froguel, P, Kadowaki, T
Published in Diabetologia (01.04.2007)
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TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals
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Published in Diabetologia (01.10.2012)
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Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
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Published in Nature (London) (12.06.2003)
Published in Nature (London) (12.06.2003)
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Transmission of Type 2 diabetes to sons and daughters: the D.E.S.I.R. cohort
Balkau, B., Roussel, R., Wagner, S., Tichet, J., Froguel, P., Fagherazzi, G., Bonnet, F.
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Dietary fat intake and polymorphisms at the PPARG locus modulate BMI and type 2 diabetes risk in the D.E.S.I.R. prospective study
LAMRI, A, ABI KHALIL, C, JAZIRI, R, VELHO, G, LANTIERI, O, VOL, S, FROGUEL, P, BALKAU, B, MARRE, M, FUMERON, F
Published in International Journal of Obesity (01.02.2012)
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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
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Published in Nature Medicine (01.08.2001)
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A frameshift mutation in human MC4R is associated with a dominant form of obesity
Clement, Karine, Froguel, Philippe, Guy-Grand, Bernard, Vaisse, Christian
Published in Nature genetics (01.10.1998)
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A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes
Thanabalasingham, G., Shah, N., Vaxillaire, M., Hansen, T., Tuomi, T., Gašperíková, D., Szopa, M., Tjora, E., James, T. J., Kokko, P., Loiseleur, F., Andersson, E., Gaget, S., Isomaa, B., Nowak, N., Raeder, H., Stanik, J., Njolstad, P. R., Malecki, M. T., Klimes, I., Groop, L., Pedersen, O., Froguel, P., McCarthy, M. I., Gloyn, A. L., Owen, K. R.
Published in Diabetologia (01.11.2011)
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GATA6 inactivating mutations are associated with heart defects and, inconsistently, with pancreatic agenesis and diabetes
Bonnefond, A., Sand, O., Guerin, B., Durand, E., De Graeve, F., Huyvaert, M., Rachdi, L., Kerr-Conte, J., Pattou, F., Vaxillaire, M., Polak, M., Scharfmann, R., Czernichow, P., Froguel, P.
Published in Diabetologia (01.10.2012)
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Insulin/Foxo1 Pathway Regulates Expression Levels of Adiponectin Receptors and Adiponectin Sensitivity
Tsuchida, Atsushi, Yamauchi, Toshimasa, Ito, Yusuke, Hada, Yusuke, Maki, Toshiyuki, Takekawa, Sato, Kamon, Junji, Kobayashi, Masaki, Suzuki, Ryo, Hara, Kazuo, Kubota, Naoto, Terauchi, Yasuo, Froguel, Philippe, Nakae, Jun, Kasuga, Masato, Accili, Domenico, Tobe, Kazuyuki, Ueki, Kohjiro, Nagai, Ryozo, Kadowaki, Takashi
Published in The Journal of biological chemistry (16.07.2004)
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Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations
Franks, P. W, Rolandsson, O, Debenham, S. L, Fawcett, K. A, Payne, F, Dina, C, Froguel, P, Mohlke, K. L, Willer, C, Olsson, T, Wareham, N. J, Hallmans, G, Barroso, I, Sandhu, M. S
Published in Diabetologia (01.03.2008)
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Placental antiangiogenic prolactin fragments are increased in human and rat maternal diabetes
Perimenis, P., Bouckenooghe, T., Delplanque, J., Moitrot, E., Eury, E., Lobbens, S., Gosset, P., Devisme, L., Duvillie, B., Abderrahmani, A., Storme, L., Fontaine, P., Froguel, P., Vambergue, A.
Published in Biochimica et biophysica acta (01.09.2014)
Published in Biochimica et biophysica acta (01.09.2014)
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European genetic variants associated with type 2 diabetes in North African Arabs
Cauchi, S, Ezzidi, I, El Achhab, Y, Mtiraoui, N, Chaieb, L, Salah, D, Nejjari, C, Labrune, Y, Yengo, L, Beury, D, Vaxillaire, M, Mahjoub, T, Chikri, M, Froguel, P
Published in Diabetes & metabolism (01.10.2012)
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The genetic abnormality in the beta cell determines the response to an oral glucose load
STRIDE, A, VAXILLAIRE, M, LORINI, R, GROOP, L, FROGUEL, P, HATTERSLEY, A. T, TUOMI, T, BARBETTI, F, NJØLSTAD, P. R, HANSEN, T, COSTA, A, CONGET, I, PEDERSEN, O, SØVIK, O
Published in Diabetologia (01.03.2002)
Published in Diabetologia (01.03.2002)
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