Epigenetic Regulation of the DLK1-MEG3 MicroRNA Cluster in Human Type 2 Diabetic Islets
Kameswaran, Vasumathi, Bramswig, Nuria C., McKenna, Lindsay B., Penn, Melinda, Schug, Jonathan, Hand, Nicholas J., Chen, Ying, Choi, Inchan, Vourekas, Anastassios, Won, Kyoung-Jae, Liu, Chengyang, Vivek, Kumar, Naji, Ali, Friedman, Joshua R., Kaestner, Klaus H.
Published in Cell metabolism (07.01.2014)
Published in Cell metabolism (07.01.2014)
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Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression
Guo, Yanxia, Walsh, Alice M, Canavan, Mary, Wechalekar, Mihir D, Cole, Suzanne, Yin, Xuefeng, Scott, Brittney, Loza, Mathew, Orr, Carl, McGarry, Trudy, Bombardieri, Michele, Humby, Frances, Proudman, Susanna M, Pitzalis, Costantino, Smith, Malcolm D, Friedman, Joshua R, Anderson, Ian, Madakamutil, Loui, Veale, Douglas J, Fearon, Ursula, Nagpal, Sunil
Published in PloS one (28.02.2018)
Published in PloS one (28.02.2018)
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Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy
Martin, Jerome C., Chang, Christie, Boschetti, Gilles, Ungaro, Ryan, Giri, Mamta, Grout, John A., Gettler, Kyle, Chuang, Ling-shiang, Nayar, Shikha, Greenstein, Alexander J., Dubinsky, Marla, Walker, Laura, Leader, Andrew, Fine, Jay S., Whitehurst, Charles E., Mbow, M Lamine, Kugathasan, Subra, Denson, Lee A., Hyams, Jeffrey S., Friedman, Joshua R., Desai, Prerak T., Ko, Huaibin M., Laface, Ilaria, Akturk, Guray, Schadt, Eric E., Salmon, Helene, Gnjatic, Sacha, Rahman, Adeeb H., Merad, Miriam, Cho, Judy H., Kenigsberg, Ephraim
Published in Cell (05.09.2019)
Published in Cell (05.09.2019)
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A functional genomics predictive network model identifies regulators of inflammatory bowel disease
Peters, Lauren A, Perrigoue, Jacqueline, Mortha, Arthur, Iuga, Alina, Song, Won-min, Neiman, Eric M, Llewellyn, Sean R, Di Narzo, Antonio, Kidd, Brian A, Telesco, Shannon E, Zhao, Yongzhong, Stojmirovic, Aleksandar, Sendecki, Jocelyn, Shameer, Khader, Miotto, Riccardo, Losic, Bojan, Shah, Hardik, Lee, Eunjee, Wang, Minghui, Faith, Jeremiah J, Kasarskis, Andrew, Brodmerkel, Carrie, Curran, Mark, Das, Anuk, Friedman, Joshua R, Fukui, Yoshinori, Humphrey, Mary Beth, Iritani, Brian M, Sibinga, Nicholas, Tarrant, Teresa K, Argmann, Carmen, Hao, Ke, Roussos, Panos, Zhu, Jun, Zhang, Bin, Dobrin, Radu, Mayer, Lloyd F, Schadt, Eric E
Published in Nature genetics (01.10.2017)
Published in Nature genetics (01.10.2017)
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Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria
Sonnenberg, Gregory F., Monticelli, Laurel A., Alenghat, Theresa, Fung, Thomas C., Hutnick, Natalie A., Kunisawa, Jun, Shibata, Naoko, Grunberg, Stephanie, Sinha, Rohini, Zahm, Adam M., Tardif, Mélanie R., Sathaliyawala, Taheri, Kubota, Masaru, Farber, Donna L., Collman, Ronald G., Shaked, Abraham, Fouser, Lynette A., Weiner, David B., Tessier, Philippe A., Friedman, Joshua R., Kiyono, Hiroshi, Bushman, Frederic D., Chang, Kyong-Mi, Artis, David
Published in Science (American Association for the Advancement of Science) (08.06.2012)
Published in Science (American Association for the Advancement of Science) (08.06.2012)
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MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function
McKenna, Lindsay B, Schug, Jonathan, Vourekas, Anastassios, McKenna, Jaime B, Bramswig, Nuria C, Friedman, Joshua R, Kaestner, Klaus H
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2010)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2010)
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Effects of Ustekinumab on Histologic Disease Activity in Patients With Crohn’s Disease
Li, Katherine, Friedman, Joshua R., Chan, Daphne, Pollack, Paul, Yang, Feifei, Jacobstein, Douglas, Brodmerkel, Carrie, Gasink, Christopher, Feagan, Brian G., Sandborn, William J., Rutgeerts, Paul, De Hertogh, Gert
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2019)
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Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development
Gao, Nan, LeLay, John, Vatamaniuk, Marko Z, Rieck, Sebastian, Friedman, Joshua R, Kaestner, Klaus H
Published in Genes & development (15.12.2008)
Published in Genes & development (15.12.2008)
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Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2–related Disease
Suárez-Fariñas, Mayte, Tokuyama, Minami, Wei, Gabrielle, Huang, Ruiqi, Livanos, Alexandra, Jha, Divya, Levescot, Anais, Irizar, Haritz, Kosoy, Roman, Cording, Sascha, Wang, Wenhui, Losic, Bojan, Ungaro, Ryan C., Di’Narzo, Antonio, Martinez-Delgado, Gustavo, Suprun, Maria, Corley, Michael J., Stojmirovic, Aleksandar, Houten, Sander M., Peters, Lauren, Curran, Mark, Brodmerkel, Carrie, Perrigoue, Jacqueline, Friedman, Joshua R., Hao, Ke, Schadt, Eric E., Zhu, Jun, Ko, Huaibin M., Cho, Judy, Dubinsky, Marla C., Sands, Bruce E., Ndhlovu, Lishomwa, Cerf-Bensusan, Nadine, Kasarskis, Andrew, Colombel, Jean-Frederic, Harpaz, Noam, Argmann, Carmen, Mehandru, Saurabh
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2021)
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Using EGFR amplification to stratify recurrent glioblastoma treated with immune checkpoint inhibitors
Friedman, Joshua S., Jun, Tomi, Rashidipour, Omid, Huang, Kuan-lin, Ellis, Ethan, Kadaba, Priyanka, Belani, Puneet, Nael, Kambiz, Tsankova, Nadejda M., Sebra, Robert, Hormigo, Adília
Published in Cancer Immunology, Immunotherapy (01.06.2023)
Published in Cancer Immunology, Immunotherapy (01.06.2023)
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Molecular Comparison of Adult and Pediatric Ulcerative Colitis Indicates Broad Similarity of Molecular Pathways in Disease Tissue
Li, Katherine, Strauss, Richard, Ouahed, Jodie, Chan, Daphne, Telesco, Shannon E., Shouval, Dror S., Canavan, James B., Brodmerkel, Carrie, Snapper, Scott B., Friedman, Joshua R.
Published in Journal of pediatric gastroenterology and nutrition (01.07.2018)
Published in Journal of pediatric gastroenterology and nutrition (01.07.2018)
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MicroRNA‐122 regulates polyploidization in the murine liver
Hsu, Shu‐hao, Delgado, Evan R., Otero, P. Anthony, Teng, Kun‐yu, Kutay, Huban, Meehan, Kolin M., Moroney, Justin B., Monga, Jappmann K., Hand, Nicholas J., Friedman, Joshua R., Ghoshal, Kalpana, Duncan, Andrew W.
Published in Hepatology (Baltimore, Md.) (01.08.2016)
Published in Hepatology (Baltimore, Md.) (01.08.2016)
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Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy
Pavlidis, Polychronis, Tsakmaki, Anastasia, Pantazi, Eirini, Li, Katherine, Cozzetto, Domenico, Digby- Bell, Jonathan, Yang, Feifei, Lo, Jonathan W., Alberts, Elena, Sa, Ana Caroline Costa, Niazi, Umar, Friedman, Joshua, Long, Anna K., Ding, Yuchun, Carey, Christopher D., Lamb, Christopher, Saqi, Mansoor, Madgwick, Matthew, Gul, Leila, Treveil, Agatha, Korcsmaros, Tamas, Macdonald, Thomas T., Lord, Graham M., Bewick, Gavin, Powell, Nick
Published in Nature communications (03.10.2022)
Published in Nature communications (03.10.2022)
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Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets
Di'Narzo, Antonio F., Houten, Sander M., Kosoy, Roman, Huang, Ruiqi, Vaz, Frédéric M., Hou, Ruixue, Wei, Gabrielle, Wang, Wenhui, Comella, Phillip H., Dodatko, Tetyana, Rogatsky, Eduard, Stojmirovic, Aleksandar, Brodmerkel, Carrie, Perrigoue, Jacqueline, Hart, Amy, Curran, Mark, Friedman, Joshua R., Zhu, Jun, Agrawal, Manasi, Cho, Judy, Ungaro, Ryan, Dubinsky, Marla C., Sands, Bruce E., Suárez-Fariñas, Mayte, Schadt, Eric E., Colombel, Jean-Frédéric, Kasarskis, Andrew, Hao, Ke, Argmann, Carmen
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2022)
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Relationship Between Combined Histologic and Endoscopic Endpoints and Efficacy of Ustekinumab Treatment in Patients With Ulcerative Colitis
Li, Katherine, Marano, Colleen, Zhang, Hongyan, Yang, Feifei, Sandborn, William J., Sands, Bruce E., Feagan, Brian G., Rubin, David T., Peyrin-Biroulet, Laurent, Friedman, Joshua R., De Hertogh, Gert
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2020)
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