Proteasomal Degradation of Human CYP1B1: Effect of the Asn453Ser Polymorphism on the Post-Translational Regulation of CYP1B1 Expression
Bandiera, Silvio, Weidlich, Simone, Harth, Volker, Broede, Peter, Ko, Yun, Friedberg, Thomas
Published in Molecular pharmacology (01.02.2005)
Published in Molecular pharmacology (01.02.2005)
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AMP-activated Protein Kinase Mediates Phenobarbital Induction of CYP2B Gene Expression in Hepatocytes and a Newly Derived Human Hepatoma Cell Line
Rencurel, Franck, Stenhouse, Alasdair, Hawley, Simon A., Friedberg, Thomas, Hardie, D. Grahame, Sutherland, Calum, Wolf, C. Roland
Published in The Journal of biological chemistry (11.02.2005)
Published in The Journal of biological chemistry (11.02.2005)
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Glucuronidation as a mechanism of intrinsic drug resistance in colon cancer cells: contribution of drug transport proteins
Cummings, Jeffrey, Zelcer, Noam, Allen, John D, Yao, Denggao, Boyd, Gary, Maliepaard, Mark, Friedberg, Thomas H, Smyth, John F, Jodrell, Duncan I
Published in Biochemical pharmacology (2004)
Published in Biochemical pharmacology (2004)
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Directional trans-epithelial transport of organic anions in porcine LLC-PK1 cells that co-express human OATP1B1 (OATP-C) and MRP2
Spears, Kevin J., Ross, Jillian, Stenhouse, Alasdair, Ward, Clive J., Goh, Lay-Beng, Wolf, C. Roland, Morgan, Paul, Ayrton, Andy, Friedberg, Thomas H.
Published in Biochemical pharmacology (01.02.2005)
Published in Biochemical pharmacology (01.02.2005)
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Differential effects of fluvoxamine and other antidepressants on the biotransformation of melatonin
Härtter, S, Wang, X, Weigmann, H, Friedberg, T, Arand, M, Oesch, F, Hiemke, C
Published in Journal of clinical psychopharmacology (01.04.2001)
Published in Journal of clinical psychopharmacology (01.04.2001)
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Electrospray Ionization Mass Spectrometric Analysis of Intact Cytochrome P450: Identification of Tienilic Acid Adducts to P450 2C9
Koenigs, Luke L, Peter, Raimund M, Hunter, Ann P, Haining, Robert L, Rettie, Allan E, Friedberg, Thomas, Pritchard, Michael P, Shou, Magang, Rushmore, Thomas H, Trager, William F
Published in Biochemistry (Easton) (23.02.1999)
Published in Biochemistry (Easton) (23.02.1999)
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Coexpression of a human P450 (CYP3A4) and P450 reductase generates a highly functional monooxygenase system in Escherichia coli
Blake, Jennifer A.R., Pritchard, Mike, Ding, Shaohong, Smith, Graeme C.M., Burchell, Brian, Wolf, C.Roland, Friedberg, Thomas
Published in FEBS letters (18.11.1996)
Published in FEBS letters (18.11.1996)
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CYP3A4 Active Site Volume Modification by Mutagenesis of Leucine 211
FOWLER, Stephen M, TAYLOR, John M, FRIEDBERG, Thomas, WOLF, C. Roland, RILEY, Robert J
Published in Drug metabolism and disposition (01.04.2002)
Published in Drug metabolism and disposition (01.04.2002)
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A Keratinocyte-specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid
Keeney, Diane S., Skinner, Colin, Wei, Shozuo, Friedberg, Thomas, Waterman, Michael R.
Published in The Journal of biological chemistry (10.04.1998)
Published in The Journal of biological chemistry (10.04.1998)
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Rapid Characterization of the Major Drug-Metabolizing Human Hepatic Cytochrome P-450 Enzymes Expressed in Escherichia coli
MCGINNITY, D. F, GRIFFIN, S. J, MOODY, G. C, VOICE, M, HANLON, S, FRIEDBERG, T, RILEY, R. J
Published in Drug metabolism and disposition (01.09.1999)
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Published in Drug metabolism and disposition (01.09.1999)
Journal Article
Competition Between Cytochrome P-450 Isozymes for NADPH-Cytochrome P-450 Oxidoreductase Affects Drug Metabolism
Li, D N, Pritchard, M P, Hanlon, S P, Burchell, B, Wolf, C R, Friedberg, T
Published in The Journal of pharmacology and experimental therapeutics (01.05.1999)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1999)
Journal Article
High Levels of Recombinant CYP3A4 Expression in Chinese Hamster Ovary Cells Are Modulated by Coexpressed Human P450 Reductase and Hemin Supplementation
Ding, Shaohong, Yao, Denggao, Burchell, Brian, Wolf, C.Roland, Friedberg, Thomas
Published in Archives of biochemistry and biophysics (15.12.1997)
Published in Archives of biochemistry and biophysics (15.12.1997)
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Journal Article
Effects of Human Cytochrome b5on CYP3A4 Activity and Stabilityin Vivo
Voice, Mike W., Zhang, Yan, Wolf, C.Roland, Burchell, Brian, Friedberg, Thomas
Published in Archives of biochemistry and biophysics (01.06.1999)
Published in Archives of biochemistry and biophysics (01.06.1999)
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A General Strategy for the Expression of Recombinant Human Cytochrome P450s inEscherichia coliUsing Bacterial Signal Peptides: Expression of CYP3A4, CYP2A6, and CYP2E1
Pritchard, Michael P., Ossetian, Richard, Li, Dongtao N., Henderson, Colin J., Burchell, Brian, Wolf, C.Roland, Friedberg, Thomas
Published in Archives of biochemistry and biophysics (01.09.1997)
Published in Archives of biochemistry and biophysics (01.09.1997)
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Journal Article
An amperometric biosensor with human CYP3A4 as a novel drug screening tool
Joseph, Shiba, Rusling, James F., Lvov, Yuri M., Friedberg, Thomas, Fuhr, Uwe
Published in Biochemical pharmacology (01.06.2003)
Published in Biochemical pharmacology (01.06.2003)
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