Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK pathways
Tan, Xin, Xu, Aizhang, Zhao, Tuo, Zhao, Qin, Zhang, Jun, Fan, Cuihong, Deng, Yulin, Freywald, Andrew, Genth, Harald, Xiang, Jim
Published in Scientific reports (28.02.2018)
Published in Scientific reports (28.02.2018)
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Journal Article
TLR9 agonist enhances radiofrequency ablation-induced CTL responses, leading to the potent inhibition of primary tumor growth and lung metastasis
Xu, Aizhang, Zhang, Lifeng, Yuan, Jingying, Babikr, Fatma, Freywald, Andrew, Chibbar, Rajni, Moser, Michael, Zhang, Wenjun, Zhang, Bing, Fu, Zhaoying, Xiang, Jim
Published in Cellular & molecular immunology (01.10.2019)
Published in Cellular & molecular immunology (01.10.2019)
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Journal Article
Structure of the EphB6 receptor ectodomain
Mason, Emilia O, Goldgur, Yehuda, Robev, Dorothea, Freywald, Andrew, Nikolov, Dimitar B, Himanen, Juha P
Published in PloS one (26.03.2021)
Published in PloS one (26.03.2021)
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Journal Article
Novel exosome-targeted T-cell-based vaccine counteracts T-cell anergy and converts CTL exhaustion in chronic infection via CD40L signaling through the mTORC1 pathway
Wang, Rong, Xu, Aizhang, Zhang, Xueying, Wu, Jie, Freywald, Andrew, Xu, Jianqing, Xiang, Jim
Published in Cellular & molecular immunology (01.06.2017)
Published in Cellular & molecular immunology (01.06.2017)
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Journal Article
Mining the plasma-proteome associated genes in patients with gastro-esophageal cancers for biomarker discovery
Vizeacoumar, Frederick S., Guo, Hongyu, Dwernychuk, Lynn, Zaidi, Adnan, Freywald, Andrew, Wu, Fang-Xiang, Vizeacoumar, Franco J., Ahmed, Shahid
Published in Scientific reports (07.04.2021)
Published in Scientific reports (07.04.2021)
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Journal Article
An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer
Auslander, Noam, Cunningham, Chelsea E, Toosi, Behzad M, McEwen, Emily J, Yizhak, Keren, Vizeacoumar, Frederick S, Parameswaran, Sreejit, Gonen, Nir, Freywald, Tanya, Bhanumathy, Kalpana K, Freywald, Andrew, Vizeacoumar, Franco J, Ruppin, Eytan
Published in Molecular systems biology (01.12.2017)
Published in Molecular systems biology (01.12.2017)
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Journal Article
Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR
Hanover, Glinton, Vizeacoumar, Frederick S., Banerjee, Sara L., Nair, Raveena, Dahiya, Renuka, Osornio-Hernandez, Ana I., Morales, Alain Morejon, Freywald, Tanya, Himanen, Juha P., Toosi, Behzad M., Bisson, Nicolas, Vizeacoumar, Franco J., Freywald, Andrew
Published in Cell reports (Cambridge) (25.07.2023)
Published in Cell reports (Cambridge) (25.07.2023)
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Journal Article
MEMO1 binds iron and modulates iron homeostasis in cancer cells
Dolgova, Natalia, Uhlemann, Eva-Maria E, Boniecki, Michal T, Vizeacoumar, Frederick S, Ara, Anjuman, Nouri, Paria, Ralle, Martina, Tonelli, Marco, Abbas, Syed A, Patry, Jaala, Elhasasna, Hussain, Freywald, Andrew, Vizeacoumar, Franco J, Dmitriev, Oleg Y
Published in eLife (19.04.2024)
Published in eLife (19.04.2024)
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Journal Article
Synthetic lethal interactions of DEAD/H-box helicases as targets for cancer therapy
Arna, Ananna Bhadra, Patel, Hardikkumar, Singh, Ravi Shankar, Vizeacoumar, Frederick S, Kusalik, Anthony, Freywald, Andrew, Vizeacoumar, Franco J, Wu, Yuliang
Published in Frontiers in oncology (26.01.2023)
Published in Frontiers in oncology (26.01.2023)
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Journal Article
The CINs of Polo-Like Kinase 1 in Cancer
Cunningham, Chelsea E., MacAuley, Mackenzie J., Vizeacoumar, Frederick S., Abuhussein, Omar, Freywald, Andrew, Vizeacoumar, Franco J.
Published in Cancers (13.10.2020)
Published in Cancers (13.10.2020)
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Journal Article
Systematic Comparison of CRISPR and shRNA Screens to Identify Essential Genes Using a Graph-Based Unsupervised Learning Model
Ding, Yulian, Denomy, Connor, Freywald, Andrew, Pan, Yi, Vizeacoumar, Franco J, Vizeacoumar, Frederick S, Wu, Fang-Xiang
Published in Cells (Basel, Switzerland) (04.10.2024)
Published in Cells (Basel, Switzerland) (04.10.2024)
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Journal Article
Identification of novel genes involved in apoptosis of HIV-infected macrophages using unbiased genome-wide screening
Dong, Simon X. M, Vizeacoumar, Frederick S, Bhanumathy, Kalpana K, Alli, Nezeka, Gonzalez-Lopez, Cristina, Gajanayaka, Niranjala, Caballero, Ramon, Ali, Hamza, Freywald, Andrew, Cassol, Edana, Angel, Jonathan B, Vizeacoumar, Franco J, Kumar, Ashok
Published in BMC infectious diseases (07.07.2021)
Published in BMC infectious diseases (07.07.2021)
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Journal Article
Spindle Checkpoint Factors Bub1 and Bub2 Promote DNA Double-Strand Break Repair by Nonhomologous End Joining
Jessulat, Matthew, Malty, Ramy H., Nguyen-Tran, Diem-Hang, Deineko, Viktor, Aoki, Hiroyuki, Vlasblom, James, Omidi, Katayoun, Jin, Ke, Minic, Zoran, Hooshyar, Mohsen, Burnside, Daniel, Samanfar, Bahram, Phanse, Sadhna, Freywald, Tanya, Prasad, Bhanu, Zhang, Zhaolei, Vizeacoumar, Franco, Krogan, Nevan J., Freywald, Andrew, Golshani, Ashkan, Babu, Mohan
Published in Molecular and cellular biology (01.07.2015)
Published in Molecular and cellular biology (01.07.2015)
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Journal Article
A Drug Repurposing Screen Identifies Fludarabine Phosphate as a Potential Therapeutic Agent for N-MYC Overexpressing Neuroendocrine Prostate Cancers
Elhasasna, Hussain, Khan, Raymond, Bhanumathy, Kalpana K., Vizeacoumar, Frederick S., Walke, Prachi, Bautista, Maricris, Dahiya, Dinesh K., Maranda, Vincent, Patel, Hardikkumar, Balagopal, Amrutha, Alli, Nezeka, Krishnan, Anand, Freywald, Andrew, Vizeacoumar, Franco J.
Published in Cells (Basel, Switzerland) (20.07.2022)
Published in Cells (Basel, Switzerland) (20.07.2022)
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Journal Article
Th cells promote CTL survival and memory via acquired pMHC-I and endogenous IL-2 and CD40L signaling and by modulating apoptosis-controlling pathways
Umeshappa, Channakeshava Sokke, Xie, Yufeng, Xu, Shulin, Nanjundappa, Roopa Hebbandi, Freywald, Andrew, Deng, Yulin, Ma, Hong, Xiang, Jim
Published in PloS one (13.06.2013)
Published in PloS one (13.06.2013)
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Journal Article
The intrinsically kinase-inactive EPHB6 receptor predisposes cancer cells to DR5-induced apoptosis by promoting mitochondrial fragmentation
El Zawily, Amr M, Toosi, Behzad M, Freywald, Tanya, Indukuri, Vijaya V, Vizeacoumar, Franco J, Leary, Scot C, Freywald, Andrew
Published in Oncotarget (22.11.2016)
Published in Oncotarget (22.11.2016)
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Journal Article
CD154 and IL-2 signaling of CD4+ T cells play a critical role in multiple phases of CD8+ CTL responses following adenovirus vaccination
Sokke Umeshappa, Channakeshava, Hebbandi Nanjundappa, Roopa, Xie, Yufeng, Freywald, Andrew, Deng, Yulin, Ma, Hong, Xiang, Jim
Published in PloS one (05.10.2012)
Published in PloS one (05.10.2012)
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Journal Article
Glycosylation States of Pre- and Post-synaptic Markers of 5-HT Neurons Differ With Sex and 5-HTTLPR Genotype in Cortical Autopsy Samples
Nyarko, Jennifer N K, Quartey, Maa O, Heistad, Ryan M, Pennington, Paul R, Poon, Lisa J, Knudsen, Kaeli J, Allonby, Odette, El Zawily, Amr M, Freywald, Andrew, Rauw, Gail, Baker, Glen B, Mousseau, Darrell D
Published in Frontiers in neuroscience (10.08.2018)
Published in Frontiers in neuroscience (10.08.2018)
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Journal Article
Molecular characterization of an MLL1 fusion and its role in chromosomal instability
Parameswaran, Sreejit, Vizeacoumar, Frederick S., Kalyanasundaram Bhanumathy, Kalpana, Qin, Fujun, Islam, Md. Fahmid, Toosi, Behzad M., Cunningham, Chelsea E., Mousseau, Darrell D., Uppalapati, Maruti C., Stirling, Peter C., Wu, Yuliang, Bonham, Keith, Freywald, Andrew, Li, Hui, Vizeacoumar, Franco J.
Published in Molecular oncology (01.02.2019)
Published in Molecular oncology (01.02.2019)
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Journal Article