Murine intestinal stem cells are highly sensitive to modulation of the T3/TRα1-dependent pathway
Godart, Matthias, Frau, Carla, Farhat, Diana, Giolito, Maria Virginia, Jamard, Catherine, Le Nevé, Clementine, Freund, Jean-Noel, Penalva, Luiz O, Sirakov, Maria, Plateroti, Michelina
Published in Development (Cambridge) (15.04.2021)
Published in Development (Cambridge) (15.04.2021)
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Macrophage depletion overcomes human hematopoietic cell engraftment failure in zebrafish embryo
El Omar, Reine, Abdellaoui, Naoill, Coulibaly, Safiatou T., Fontenille, Laura, Lanza, François, Gachet, Christian, Freund, Jean-Noel, Negroni, Matteo, Kissa, Karima, Tavian, Manuela
Published in Cell death & disease (01.05.2024)
Published in Cell death & disease (01.05.2024)
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Regulation of the THRA gene, encoding the thyroid hormone nuclear receptor TRα1, in intestinal lesions
Giolito, Maria Virginia, La Rosa, Théo, Farhat, Diana, Bodoirat, Serguei, Guardia, Gabriela D. A., Domon‐Dell, Claire, Galante, Pedro A. F., Freund, Jean‐Noel, Plateroti, Michelina
Published in Molecular oncology (01.12.2022)
Published in Molecular oncology (01.12.2022)
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General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions
Säisä-Borreill, Susanna, Davidson, Guillaume, Kleiber, Thomas, Thevenot, Andréa, Martin, Elisabeth, Mondot, Stanislas, Blottière, Hervé, Helleux, Alexandra, Mengus, Gabrielle, Plateroti, Michelina, Duluc, Isabelle, Davidson, Irwin, Freund, Jean-Noel
Published in Cell death and differentiation (01.03.2023)
Published in Cell death and differentiation (01.03.2023)
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Mesalazine initiates an anti-oncogenic β-catenin / MUCDHL negative feed-back loop in colon cancer cells by cell-specific mechanisms
Bersuder, Emilie, Terciolo, Chloe, Lechevrel, Mathilde, Martin, Elisabeth, Quesnelle, Celine, Freund, Jean-Noel, Reimund, Jean-Marie, Gross, Isabelle
Published in Biomedicine & pharmacotherapy (01.02.2022)
Published in Biomedicine & pharmacotherapy (01.02.2022)
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A redox ruthenium compound directly targets PHD2 and inhibits the HIF1 pathway to reduce tumor angiogenesis independently of p53
Vidimar, Vania, Licona, Cynthia, Cerón-Camacho, Ricardo, Guerin, Eric, Coliat, Pierre, Venkatasamy, Aina, Ali, Moussa, Guenot, Dominique, Le Lagadec, Ronan, Jung, Alain C., Freund, Jean-Noel, Pfeffer, Michel, Mellitzer, Georg, Sava, Gianni, Gaiddon, Christian
Published in Cancer letters (01.01.2019)
Published in Cancer letters (01.01.2019)
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NADPH Oxidase 1 Modulates WNT and NOTCH1 Signaling To Control the Fate of Proliferative Progenitor Cells in the Colon
Coant, Nicolas, Ben Mkaddem, Sanae, Pedruzzi, Eric, Guichard, Cécile, Tréton, Xavier, Ducroc, Robert, Freund, Jean-Noel, Cazals-Hatem, Dominique, Bouhnik, Yoram, Woerther, Paul-Louis, Skurnik, David, Grodet, Alain, Fay, Michèle, Biard, Denis, Lesuffleur, Thécla, Deffert, Christine, Moreau, Richard, Groyer, André, Krause, Karl-Heinz, Daniel, Fanny, Ogier-Denis, Eric
Published in Molecular and Cellular Biology (01.06.2010)
Published in Molecular and Cellular Biology (01.06.2010)
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Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL
Passet, Marie, Kim, Rathana, Gachet, Stéphanie, Sigaux, François, Chaumeil, Julie, Galland, Ava, Sexton, Thomas, Quentin, Samuel, Hernandez, Lucie, Larcher, Lise, Bergugnat, Hugo, Ye, Tao, Karasu, Nezih, Caye, Aurélie, Heizmann, Beate, Duluc, Isabelle, Chevallier, Patrice, Rousselot, Philippe, Huguet, Françoise, Leguay, Thibaut, Hunault, Mathilde, Pflumio, Françoise, Freund, Jean-Noël, Lobry, Camille, Lhéritier, Véronique, Dombret, Hervé, Domon-Dell, Claire, Soulier, Jean, Boissel, Nicolas, Clappier, Emmanuelle
Published in Blood (16.06.2022)
Published in Blood (16.06.2022)
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The tumor suppressor CDX2 opposes pro-metastatic biomechanical modifications of colon cancer cells through organization of the actin cytoskeleton
Platet, Nadine, Hinkel, Isabelle, Richert, Ludovic, Murdamoothoo, Devadarssen, Moufok-Sadoun, Ahlam, Vanier, Marie, Lavalle, Philippe, Gaiddon, Christian, Vautier, Dominique, Freund, Jean-Noel, Gross, Isabelle
Published in Cancer letters (01.02.2017)
Published in Cancer letters (01.02.2017)
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Combined NADPH oxidase 1 and interleukin 10 deficiency induces chronic endoplasmic reticulum stress and causes ulcerative colitis-like disease in mice
Tréton, Xavier, Pedruzzi, Eric, Guichard, Cécile, Ladeiro, Yannick, Sedghi, Shirin, Vallée, Mélissa, Fernandez, Neike, Bruyère, Emilie, Woerther, Paul-Louis, Ducroc, Robert, Montcuquet, Nicolas, Freund, Jean-Noel, Van Seuningen, Isabelle, Barreau, Frédérick, Marah, Assiya, Hugot, Jean-Pierre, Cazals-Hatem, Dominique, Bouhnik, Yoram, Daniel, Fanny, Ogier-Denis, Eric
Published in PloS one (09.07.2014)
Published in PloS one (09.07.2014)
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Anticancer activity of ruthenium and osmium cyclometalated compounds: identification of ABCB1 and EGFR as resistance mechanisms
Licona, Cynthia, Delhorme, Jean-Baptiste, Riegel, Gilles, Vidimar, Vania, Cerón-Camacho, Ricardo, Boff, Bastien, Venkatasamy, Aina, Tomasetto, Catherine, da Silva Figueiredo Celestino Gomes, Priscila, Rognan, Didier, Freund, Jean-Noel, Le Lagadec, Ronan, Pfeffer, Michel, Gross, Isabelle, Mellitzer, Georg, Gaiddon, Christian
Published in Inorganic chemistry frontiers (04.02.2020)
Published in Inorganic chemistry frontiers (04.02.2020)
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TAF4 inactivation reveals the 3 dimensional growth promoting activities of collagen 6A3
Martianov, Igor, Cler, Emilie, Duluc, Isabelle, Vicaire, Serge, Philipps, Muriel, Freund, Jean-Noel, Davidson, Irwin
Published in PloS one (03.02.2014)
Published in PloS one (03.02.2014)
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Transcriptional Regulation of the Intestinal Nuclear Bile Acid Farnesoid X Receptor (FXR) by the caudal-related Homeobox 2 (CDX2)
Modica, Salvatore, Cariello, Marica, Morgano, Annalisa, Gross, Isabelle, Vegliante, Maria Carmela, Murzilli, Stefania, Salvatore, Lorena, Freund, Jean-Noel, Sabbà, Carlo, Moschetta, Antonio
Published in The Journal of biological chemistry (10.10.2014)
Published in The Journal of biological chemistry (10.10.2014)
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Contribution of soft substrates to malignancy and tumor suppression during colon cancer cell division
Rabineau, Morgane, Kocgozlu, Leyla, Dujardin, Denis, Senger, Bernard, Haikel, Youssef, Voegel, Jean-Claude, Freund, Jean-Noel, Schaaf, Pierre, Lavalle, Philippe, Vautier, Dominique
Published in PloS one (22.10.2013)
Published in PloS one (22.10.2013)
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The control of chromosome segregation during mitosis in epithelial cells by substrate elasticity
Kocgozlu, Leyla, Rabineau, Morgane, Koenig, Géraldine, Haikel, Youssef, Schaaf, Pierre, Freund, Jean-Noel, Voegel, Jean-Claude, Lavalle, Philippe, Vautier, Dominique
Published in Biomaterials (01.01.2012)
Published in Biomaterials (01.01.2012)
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Inflammatory bowel disease in rats: Bacterial and chemical interaction
Hajj Hussein, Inaya-Abdallah, Tohme, Rania, Barada, Kassem, Mostafa, Mostafa Hassan, Freund, Jean-Noel, Jurjus, Rosalyn A, Karam, Walid, Jurjus, Abdo
Published in World journal of gastroenterology : WJG (07.07.2008)
Published in World journal of gastroenterology : WJG (07.07.2008)
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Down-regulation of the Tumor Suppressor PTEN by the Tumor Necrosis Factor-α/Nuclear Factor-κB (NF-κB)-inducing Kinase/NF-κB Pathway Is Linked to a Default IκB-α Autoregulatory Loop
Kim, Sunghoon, Domon-Dell, Claire, Kang, Junghee, Chung, Dai H., Freund, Jean-Noel, Evers, B. Mark
Published in The Journal of biological chemistry (06.02.2004)
Published in The Journal of biological chemistry (06.02.2004)
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Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation
GESPACH, Christian, GROSS, Isabelle, LHERMITTE, Benoit, DOMON-DELL, Claire, DULUC, Isabelle, MARTIN, Elisabeth, GAIDDON, Christian, KEDINGER, Michele, FREUND, Jean-Noël
Published in Oncogene (01.12.2005)
Published in Oncogene (01.12.2005)
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