Between a Rock and a Hard Place: An Epigenetic-Centric View of Testicular Germ Cell Tumors
Singh, Ratnakar, Fazal, Zeeshan, Freemantle, Sarah J, Spinella, Michael J
Published in Cancers (25.03.2021)
Published in Cancers (25.03.2021)
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MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors
Liu, Xi, Sempere, Lorenzo F, Ouyang, Haoxu, Memoli, Vincent A, Andrew, Angeline S, Luo, Yue, Demidenko, Eugene, Korc, Murray, Shi, Wei, Preis, Meir, Dragnev, Konstantin H, Li, Hua, Direnzo, James, Bak, Mads, Freemantle, Sarah J, Kauppinen, Sakari, Dmitrovsky, Ethan
Published in The Journal of clinical investigation (01.04.2010)
Published in The Journal of clinical investigation (01.04.2010)
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The Ubiquitin-Specific Peptidase USP18 Promotes Lipolysis, Fatty Acid Oxidation, and Lung Cancer Growth
Liu, Xi, Lu, Yun, Chen, Zibo, Liu, Xiuxia, Hu, Weiguo, Zheng, Lin, Chen, Yulong, Kurie, Jonathan M, Shi, Mi, Mustachio, Lisa Maria, Adresson, Thorkell, Fox, Stephen, Roszik, Jason, Kawakami, Masanori, Freemantle, Sarah J, Dmitrovsky, Ethan
Published in Molecular cancer research (01.04.2021)
Published in Molecular cancer research (01.04.2021)
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Evidence for tankyrases as antineoplastic targets in lung cancer
Busch, Alexander M, Johnson, Kevin C, Stan, Radu V, Sanglikar, Aarti, Ahmed, Yashi, Dmitrovsky, Ethan, Freemantle, Sarah J
Published in BMC cancer (28.04.2013)
Published in BMC cancer (28.04.2013)
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Hypermethylation and global remodelling of DNA methylation is associated with acquired cisplatin resistance in testicular germ cell tumours
Fazal, Zeeshan, Singh, Ratnakar, Fang, Fang, Bikorimana, Emmanuel, Baldwin, Hannah, Corbet, Andrea, Tomlin, Megan, Yerby, Cliff, Adra, Nabil, Albany, Costantine, Lee, Sarah, Freemantle, Sarah J., Nephew, Kenneth P, Christensen, Brock C, Spinella, Michael J.
Published in Epigenetics (03.10.2021)
Published in Epigenetics (03.10.2021)
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Mechanisms of cisplatin sensitivity and resistance in testicular germ cell tumors
Singh, Ratnakar, Fazal, Zeeshan, Freemantle, Sarah J, Spinella, Michael J
Published in Cancer drug resistance (01.01.2019)
Published in Cancer drug resistance (01.01.2019)
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A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid Cancers
Kawakami, Masanori, Mustachio, Lisa Maria, Chen, Yulong, Chen, Zibo, Liu, Xiuxia, Wei, Cheng-Hsin, Roszik, Jason, Kittai, Adam S, Danilov, Alexey V, Zhang, Xiaoshan, Fang, Bingliang, Wang, Jing, Heymach, John V, Tyutyunyk-Massey, Liliya, Freemantle, Sarah J, Kurie, Jonathan M, Liu, Xi, Dmitrovsky, Ethan
Published in Molecular cancer therapeutics (01.03.2021)
Published in Molecular cancer therapeutics (01.03.2021)
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G0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program
Yim, Christina Y, Sekula, David J, Hever-Jardine, Mary P, Liu, Xi, Warzecha, Joshua M, Tam, Janice, Freemantle, Sarah J, Dmitrovsky, Ethan, Spinella, Michael J
Published in Cancer research (Chicago, Ill.) (01.03.2016)
Published in Cancer research (Chicago, Ill.) (01.03.2016)
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Wnt pathway activation by ADP-ribosylation
Yang, Eungi, Tacchelly-Benites, Ofelia, Wang, Zhenghan, Randall, Michael P., Tian, Ai, Benchabane, Hassina, Freemantle, Sarah, Pikielny, Claudio, Tolwinski, Nicholas S., Lee, Ethan, Ahmed, Yashi
Published in Nature communications (03.05.2016)
Published in Nature communications (03.05.2016)
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Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2
Danilov, Alexey V, Hu, Shanhu, Orr, Bernardo, Godek, Kristina, Mustachio, Lisa Maria, Sekula, David, Liu, Xi, Kawakami, Masanori, Johnson, Faye M, Compton, Duane A, Freemantle, Sarah J, Dmitrovsky, Ethan
Published in Molecular cancer therapeutics (01.11.2016)
Published in Molecular cancer therapeutics (01.11.2016)
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Reciprocal epigenetic remodeling controls testicular cancer hypersensitivity to hypomethylating agents and chemotherapy
Singh, Ratnakar, Fazal, Zeeshan, Bikorimana, Emmanuel, Boyd, Raya I., Yerby, Cliff, Tomlin, Megan, Baldwin, Hannah, Shokry, Doha, Corbet, Andrea K., Shahid, Khadeeja, Hattab, Aleyah, Freemantle, Sarah J., Spinella, Michael J.
Published in Molecular oncology (01.02.2022)
Published in Molecular oncology (01.02.2022)
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Effective Capture of Circulating Tumor Cells from a Transgenic Mouse Lung Cancer Model Using Dendrimer Surfaces Immobilized with Anti-EGFR
Myung, Ja Hye, Roengvoraphoj, Monic, Tam, Kevin A., Ma, Tian, Memoli, Vincent A., Dmitrovsky, Ethan, Freemantle, Sarah J., Hong, Seungpyo
Published in Analytical chemistry (Washington) (06.10.2015)
Published in Analytical chemistry (Washington) (06.10.2015)
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Uncovering Growth-Suppressive MicroRNAs in Lung Cancer
XI LIU, SEMPERE, Lorenzo F, DIRENZO, James, KORC, Murray, COLE, Charles N, BAK, Mads, KAUPPINEN, Sakari, DMITROVSKY, Ethan, GALIMBERTI, Fabrizio, FREEMANTLE, Sarah J, BLACK, Candice, DRAGNEV, Konstantin H, YAN MA, FIERING, Steven, MEMOLI, Vincent, HUA LI
Published in Clinical cancer research (15.02.2009)
Published in Clinical cancer research (15.02.2009)
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Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine
Albany, Costantine, Hever-Jardine, Mary P, von Herrmann, Katherine M, Yim, Christina Y, Tam, Janice, Warzecha, Joshua M, Shin, Leah, Bock, Sarah E, Curran, Brian S, Chaudhry, Aneeq S, Kim, Fred, Sandusky, George E, Taverna, Pietro, Freemantle, Sarah J, Christensen, Brock C, Einhorn, Lawrence H, Spinella, Michael J
Published in Oncotarget (10.01.2017)
Published in Oncotarget (10.01.2017)
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Evidence for the ubiquitin protease UBP43 as an antineoplastic target
Guo, Yongli, Chinyengetere, Fadzai, Dolinko, Andrey V, Lopez-Aguiar, Alexandra, Lu, Yun, Galimberti, Fabrizio, Ma, Tian, Feng, Qing, Sekula, David, Freemantle, Sarah J, Andrew, Angeline S, Memoli, Vincent, Dmitrovsky, Ethan
Published in Molecular cancer therapeutics (01.09.2012)
Published in Molecular cancer therapeutics (01.09.2012)
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High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors
Beyrouthy, Maroun J, Garner, Kristen M, Hever, Mary P, Freemantle, Sarah J, Eastman, Alan, Dmitrovsky, Ethan, Spinella, Michael J
Published in Cancer research (Chicago, Ill.) (15.12.2009)
Published in Cancer research (Chicago, Ill.) (15.12.2009)
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Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer
Kawakami, Masanori, Mustachio, Lisa Maria, Rodriguez-Canales, Jaime, Mino, Barbara, Roszik, Jason, Tong, Pan, Wang, Jing, Lee, J Jack, Myung, Ja Hye, Heymach, John V, Johnson, Faye M, Hong, Seungpyo, Zheng, Lin, Hu, Shanhu, Villalobos, Pamela Andrea, Behrens, Carmen, Wistuba, Ignacio, Freemantle, Sarah, Liu, Xi, Dmitrovsky, Ethan
Published in JNCI : Journal of the National Cancer Institute (01.06.2017)
Published in JNCI : Journal of the National Cancer Institute (01.06.2017)
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Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer
Mustachio, Lisa Maria, Lu, Yun, Tafe, Laura J, Memoli, Vincent, Rodriguez-Canales, Jaime, Mino, Barbara, Villalobos, Pamela Andrea, Wistuba, Ignacio, Katayama, Hiroyuki, Hanash, Samir M, Roszik, Jason, Kawakami, Masanori, Cho, Kwang-Jin, Hancock, John F, Chinyengetere, Fadzai, Hu, Shanhu, Liu, Xi, Freemantle, Sarah J, Dmitrovsky, Ethan
Published in Molecular cancer research (01.07.2017)
Published in Molecular cancer research (01.07.2017)
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