Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment
Hewitt, Susannah L, Bailey, Dyane, Zielinski, John, Apte, Ameya, Musenge, Faith, Karp, Russell, Burke, Shannon, Garcon, Fabien, Mishra, Ankita, Gurumurthy, Sushma, Watkins, Amanda, Arnold, Kristen, Moynihan, James, Clancy-Thompson, Eleanor, Mulgrew, Kathy, Adjei, Grace, Deschler, Katharina, Potz, Darren, Moody, Gordon, Leinster, David A, Novick, Steve, Sulikowski, Michal, Bagnall, Chris, Martin, Philip, Lapointe, Jean-Martin, Si, Han, Morehouse, Chris, Sedic, Maja, Wilkinson, Robert W, Herbst, Ronald, Frederick, Joshua P, Luheshi, Nadia
Published in Clinical cancer research (01.12.2020)
Published in Clinical cancer research (01.12.2020)
Get full text
Journal Article
Transforming Growth Factor β-Mediated Transcriptional Repression of c-myc Is Dependent on Direct Binding of Smad3 to a Novel Repressive Smad Binding Element
Frederick, Joshua P., Liberati, Nicole T., Waddell, David S., Shi, Yigong, Wang, Xiao-Fan
Published in Molecular and Cellular Biology (01.03.2004)
Published in Molecular and Cellular Biology (01.03.2004)
Get full text
Journal Article
Role for cytoplasmic nucleotide hydrolysis in hepatic function and protein synthesis
Hudson, Benjamin H., Frederick, Joshua P., Drake, Li Yin, Megosh, Louis C., Irving, Ryan P., York, John D.
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2013)
Get full text
Journal Article
Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice
Zhao, Jingsong, Shi, Wei, Wang, Yan-Ling, Chen, Hui, Bringas, Pablo, Jr, Datto, Michael B, Frederick, Joshua P, Wang, Xiao-Fan, Warburton, David
Published in American journal of physiology. Lung cellular and molecular physiology (01.03.2002)
Published in American journal of physiology. Lung cellular and molecular physiology (01.03.2002)
Get full text
Journal Article
role for a lithium-inhibited Golgi nucleotidase in skeletal development and sulfation
Frederick, Joshua P, Tafari, A. Tsahai, Wu, Sheue-Mei, Megosh, Louis C, Chiou, Shean-Tai, Irving, Ryan P, York, John D
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (19.08.2008)
Get full text
Journal Article
An Essential Role for an Inositol Polyphosphate Multikinase, Ipk2, in Mouse Embryogenesis and Second Messenger Production
Frederick, Joshua P., Mattiske, Deidre, Wofford, Jessica A., Megosh, Louis C., Drake, Li Yin, Chiou, Shean-Tai, Brigid L. M. Hogan, York, John D., Majerus, Philip W.
Published in Proceedings of the National Academy of Sciences - PNAS (14.06.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (14.06.2005)
Get full text
Journal Article
Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs
Hewitt, Susannah L, Bai, Ailin, Bailey, Dyane, Ichikawa, Kana, Zielinski, John, Karp, Russell, Apte, Ameya, Arnold, Kristen, Zacharek, Sima J, Iliou, Maria S, Bhatt, Khushbu, Garnaas, Maija, Musenge, Faith, Davis, Ashley, Khatwani, Nikhil, Su, Stephen V, MacLean, Graham, Farlow, Samuel J, Burke, Kristine, Frederick, Joshua P
Published in Science translational medicine (30.01.2019)
Published in Science translational medicine (30.01.2019)
Get more information
Journal Article
Spatial Mapping and Immunomodulatory Role of the OX40/OX40L Pathway in Human Non-Small Cell Lung Cancer
Porciuncula, Angelo, Morgado, Micaela, Gupta, Richa, Syrigos, Kostas, Meehan, Robert, Zacharek, Sima J, Frederick, Joshua P, Schalper, Kurt A
Published in Clinical cancer research (15.11.2021)
Published in Clinical cancer research (15.11.2021)
Get full text
Journal Article
Smads Bind Directly to the Jun Family of AP-1 Transcription Factors
Liberati, Nicole T., Datto, Michael B., Frederick, Joshua P., Shen, Xing, Wong, Carolyn, Rougier-Chapman, Elissa M., Wang, Xiao-Fan
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.1999)
Get full text
Journal Article
The Loss of Smad3 Results in a Lower Rate of Bone Formation and Osteopenia Through Dysregulation of Osteoblast Differentiation and Apoptosis
Borton, Anita J., Frederick, Joshua P., Datto, Michael B., Wang, Xiao‐Fan, Weinstein, Robert S.
Published in Journal of bone and mineral research (01.10.2001)
Published in Journal of bone and mineral research (01.10.2001)
Get full text
Journal Article
T-cell Responses to Individualized Neoantigen Therapy mRNA-4157 (V940) Alone or in Combination with Pembrolizumab in the Phase 1 KEYNOTE-603 Study
Gainor, Justin F., Patel, Manish R., Weber, Jeffrey S., Gutierrez, Martin, Bauman, Julie E., Clarke, Jeffrey M., Julian, Ricklie, Scott, Aaron J., Geiger, Jessica L., Kirtane, Kedar, Robert-Tissot, Celine, Coder, Brandon, Tasneem, Moomal, Sun, Jing, Zheng, Wei, Gerbereux, Lauren, Laino, Andressa, Porichis, Filippos, Pollard, Jack Russella, Hou, Peijie, Sehgal, Vasudha, Chen, Xing, Morrissey, Manju, Daghestani, Hikmat N., Feldman, Igor, Srinivasan, Lakshmi, Frederick, Joshua P., Brown, Michelle, Aanur, Praveen, Meehan, Robert, Burris, Howard A.
Published in Cancer discovery (30.08.2024)
Published in Cancer discovery (30.08.2024)
Get full text
Journal Article
β-Arrestin 2 Mediates Endocytosis of Type III TGF-β Receptor and Down-Regulation of Its Signaling
Chen, Wei, Kirkbride, Kellye C., How, Tam, Nelson, Christopher D., Mo, Jinyao, Frederick, Joshua P., Wang, Xiao-Fan, Lefkowitz, Robert J., Blobe, Gerard C.
Published in Science (American Association for the Advancement of Science) (05.09.2003)
Published in Science (American Association for the Advancement of Science) (05.09.2003)
Get full text
Journal Article
The role of Smad3 in mediating mouse hepatic stellate cell activation
Schnabl, Bernd, Kweon, Young O., Frederick, Joshua P., Wang, Xiao-Fan, Rippe, Richard A., Brenner, David A.
Published in Hepatology (Baltimore, Md.) (01.07.2001)
Published in Hepatology (Baltimore, Md.) (01.07.2001)
Get full text
Journal Article
Smad3-Smad4 and AP-1 Complexes Synergize in Transcriptional Activation of the c-Jun Promoter by Transforming Growth Factor β
Wong, Carolyn, Rougier-Chapman, Elissa M., Frederick, Joshua P., Datto, Michael B., Liberati, Nicole T., Li, Jian-Ming, Wang, Xiao-Fan
Published in Molecular and Cellular Biology (01.03.1999)
Published in Molecular and Cellular Biology (01.03.1999)
Get full text
Journal Article
Essential Role for Smad3 in Regulating MCP-1 Expression and Vascular Inflammation
Feinberg, Mark W, Shimizu, Koichi, Lebedeva, Maria, Haspel, Richard, Takayama, Kiyoshi, Chen, Zhiping, Frederick, Joshua P, Wang, Xiao-Fan, Simon, Daniel I, Libby, Peter, Mitchell, Richard N, Jain, Mukesh K
Published in Circulation research (19.03.2004)
Published in Circulation research (19.03.2004)
Get full text
Journal Article
Impaired Immune Responses and B-Cell Proliferation in Mice Lacking the Id3 Gene
Pan, Lihua, Sato, Shinichi, Frederick, Joshua P., Sun, Xiao-Hong, Zhuang, Yuan
Published in Molecular and Cellular Biology (01.09.1999)
Published in Molecular and Cellular Biology (01.09.1999)
Get full text
Journal Article
Transforming Growth Factor-β1 Inhibition of Vascular Smooth Muscle Cell Activation Is Mediated via Smad3
Feinberg, Mark W., Watanabe, Masafumi, Lebedeva, Maria A., Depina, Ana S., Hanai, Jun-ichi, Mammoto, Tadanori, Frederick, Joshua P., Wang, Xiao-Fan, Sukhatme, Vikas P., Jain, Mukesh K.
Published in The Journal of biological chemistry (16.04.2004)
Published in The Journal of biological chemistry (16.04.2004)
Get full text
Journal Article
TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein
Shen, X, Hu, P P, Liberati, N T, Datto, M B, Frederick, J P, Wang, X F
Published in Molecular biology of the cell (01.12.1998)
Published in Molecular biology of the cell (01.12.1998)
Get full text
Journal Article
IDENTIFICATION OF MULTIGENE BIOMARKERS
ROBINSON MURRAY, PILIPOVIC LEJLA, NICOLETTI RICHARD, FREDERICK JOSHUA P, FENG BIN
Year of Publication 02.09.2014
Get full text
Year of Publication 02.09.2014
Patent