Fezolinetant in the treatment of vasomotor symptoms associated with menopause
Depypere, Herman, Lademacher, Christopher, Siddiqui, Emad, Fraser, Graeme L
Published in Expert opinion on investigational drugs (03.07.2021)
Published in Expert opinion on investigational drugs (03.07.2021)
Get full text
Journal Article
Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity
Chun, Eunyoung, Lavoie, Sydney, Fonseca-Pereira, Diogo, Bae, Sena, Michaud, Monia, Hoveyda, Hamid R., Fraser, Graeme L., Gallini Comeau, Carey Ann, Glickman, Jonathan N., Fuller, Miles H., Layden, Brian T., Garrett, Wendy S.
Published in Immunity (Cambridge, Mass.) (19.11.2019)
Published in Immunity (Cambridge, Mass.) (19.11.2019)
Get full text
Journal Article
A phase 2b, randomized, placebo-controlled, double-blind, dose-ranging study of the neurokinin 3 receptor antagonist fezolinetant for vasomotor symptoms associated with menopause
Fraser, Graeme L, Lederman, Samuel, Waldbaum, Arthur, Kroll, Robin, Santoro, Nanette, Lee, Misun, Skillern, Laurence, Ramael, Steven
Published in Menopause (New York, N.Y.) (01.04.2020)
Published in Menopause (New York, N.Y.) (01.04.2020)
Get more information
Journal Article
Treatment of Menopausal Vasomotor Symptoms with Fezolinetant, a Neurokinin 3 Receptor Antagonist: A Phase 2a Trial
Depypere, Herman, Timmerman, Dirk, Donders, Gilbert, Sieprath, Peter, Ramael, Steven, Combalbert, Jean, Hoveyda, Hamid R, Fraser, Graeme L
Published in The journal of clinical endocrinology and metabolism (01.12.2019)
Published in The journal of clinical endocrinology and metabolism (01.12.2019)
Get full text
Journal Article
Effect of the neurokinin 3 receptor antagonist fezolinetant on patient-reported outcomes in postmenopausal women with vasomotor symptoms: results of a randomized, placebo-controlled, double-blind, dose-ranging study (VESTA)
Santoro, Nanette, Waldbaum, Arthur, Lederman, Samuel, Kroll, Robin, Fraser, Graeme L, Lademacher, Christopher, Skillern, Laurence, Young, James, Ramael, Steven
Published in Menopause (New York, N.Y.) (01.12.2020)
Published in Menopause (New York, N.Y.) (01.12.2020)
Get more information
Journal Article
The frequency and clinical significance of thrombocytopenia complicating critical illness: a systematic review
Hui, Phil, Cook, Deborah J, Lim, Wendy, Fraser, Graeme A, Arnold, Donald M
Published in Chest (01.02.2011)
Published in Chest (01.02.2011)
Get more information
Journal Article
Expression of Free Fatty Acid Receptor 2 by Dendritic Cells Prevents Their Expression of Interleukin 27 and Is Required for Maintenance of Mucosal Barrier and Immune Response Against Colorectal Tumors in Mice
Lavoie, Sydney, Chun, Eunyoung, Bae, Sena, Brennan, Caitlin A., Gallini Comeau, Carey Ann, Lang, Jessica K., Michaud, Monia, Hoveyda, Hamid R., Fraser, Graeme L., Fuller, Miles H., Layden, Brian T., Glickman, Jonathan N., Garrett, Wendy S.
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2020)
Get full text
Journal Article
Final 5-year findings from the phase 3 HELIOS study of ibrutinib plus bendamustine and rituximab in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma
Fraser, Graeme A.M., Chanan-Khan, Asher, Demirkan, Fatih, Santucci Silva, Rodrigo, Grosicki, Sebastian, Janssens, Ann, Mayer, Jiri, Bartlett, Nancy L., Dilhuydy, Marie-Sarah, Loscertales, Javier, Avigdor, Abraham, Rule, Simon, Samoilova, Olga, Pavlovsky, Miguel A., Goy, Andre, Mato, Anthony, Hallek, Michael, Salman, Mariya, Tamegnon, Monelle, Sun, Steven, Connor, Anne, Nottage, Kerri, Schuier, Natasha, Balasubramanian, Sriram, Howes, Angela, Cramer, Paula
Published in Leukemia & lymphoma (09.11.2020)
Published in Leukemia & lymphoma (09.11.2020)
Get full text
Journal Article
Randomized Controlled Trial of Neurokinin 3 Receptor Antagonist Fezolinetant for Treatment of Polycystic Ovary Syndrome
Fraser, Graeme L, Obermayer-Pietsch, Barbara, Laven, Joop, Griesinger, Georg, Pintiaux, Axelle, Timmerman, Dirk, Fauser, Bart C J M, Lademacher, Christopher, Combalbert, Jean, Hoveyda, Hamid R, Ramael, Steven
Published in The journal of clinical endocrinology and metabolism (01.09.2021)
Published in The journal of clinical endocrinology and metabolism (01.09.2021)
Get full text
Journal Article
Characterization of atrial fibrillation adverse events reported in ibrutinib randomized controlled registration trials
Brown, Jennifer R, Moslehi, Javid, O'Brien, Susan, Ghia, Paolo, Hillmen, Peter, Cymbalista, Florence, Shanafelt, Tait D, Fraser, Graeme, Rule, Simon, Kipps, Thomas J, Coutre, Steven, Dilhuydy, Marie-Sarah, Cramer, Paula, Tedeschi, Alessandra, Jaeger, Ulrich, Dreyling, Martin, Byrd, John C, Howes, Angela, Todd, Michael, Vermeulen, Jessica, James, Danelle F, Clow, Fong, Styles, Lori, Valentino, Rudy, Wildgust, Mark, Mahler, Michelle, Burger, Jan A
Published in Haematologica (Roma) (01.10.2017)
Published in Haematologica (Roma) (01.10.2017)
Get full text
Journal Article
The NK3 Receptor Antagonist ESN364 Interrupts Pulsatile LH Secretion and Moderates Levels of Ovarian Hormones Throughout the Menstrual Cycle
Fraser, Graeme L, Hoveyda, Hamid R, Clarke, Iain J, Ramaswamy, Suresh, Plant, Tony M, Rose, Claudia, Millar, Robert P
Published in Endocrinology (Philadelphia) (01.11.2015)
Published in Endocrinology (Philadelphia) (01.11.2015)
Get full text
Journal Article
Lentivirus-mediated gene therapy for Fabry disease
Khan, Aneal, Barber, Dwayne L., Huang, Ju, Rupar, C. Anthony, Rip, Jack W., Auray-Blais, Christiane, Boutin, Michel, O’Hoski, Pamela, Gargulak, Kristy, McKillop, William M., Fraser, Graeme, Wasim, Syed, LeMoine, Kaye, Jelinski, Shelly, Chaudhry, Ahsan, Prokopishyn, Nicole, Morel, Chantal F., Couban, Stephen, Duggan, Peter R., Fowler, Daniel H., Keating, Armand, West, Michael L., Foley, Ronan, Medin, Jeffrey A.
Published in Nature communications (25.02.2021)
Published in Nature communications (25.02.2021)
Get full text
Journal Article
Increased regulatory activity of intestinal innate lymphoid cells type 3 (ILC3) prevents experimental autoimmune encephalomyelitis severity
Lazarević, Milica, Stegnjaić, Goran, Jevtić, Bojan, Despotović, Sanja, Ignjatović, Đurđica, Stanisavljević, Suzana, Nikolovski, Neda, Momčilović, Miljana, Fraser, Graeme L, Dimitrijević, Mirjana, Miljković, Đorđe
Published in Journal of neuroinflammation (18.01.2024)
Published in Journal of neuroinflammation (18.01.2024)
Get full text
Journal Article
Systematic review: efficacy and safety of rituximab for adults with idiopathic thrombocytopenic purpura
Arnold, Donald M, Dentali, Francesco, Crowther, Mark A, Meyer, Ralph M, Cook, Richard J, Sigouin, Christopher, Fraser, Graeme A, Lim, Wendy, Kelton, John G
Published in Annals of internal medicine (02.01.2007)
Published in Annals of internal medicine (02.01.2007)
Get more information
Journal Article
Current understanding of bleeding with ibrutinib use: a systematic review and meta-analysis
Caron, François, Leong, Darryl P., Hillis, Christopher, Fraser, Graeme, Siegal, Deborah
Published in Blood advances (09.05.2017)
Published in Blood advances (09.05.2017)
Get full text
Journal Article
Identification of free fatty acid receptor 2 agonists using virtual screening
Fells, James I., Ai, Xi, Weinglass, Adam, Feng, Wen, Lei, Ying, Finley, Michael, Hoveyda, Hamid R., Fraser, Graeme L., Machacek, Michelle
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
Get full text
Journal Article
Discovery and Optimization of Novel Antagonists to the Human Neurokinin‑3 Receptor for the Treatment of Sex-Hormone Disorders (Part I)
Hoveyda, Hamid R, Fraser, Graeme L, Roy, Marie-Odile, Dutheuil, Guillaume, Batt, Frédéric, El Bousmaqui, Mohamed, Korac, Julien, Lenoir, François, Lapin, Alexey, Noël, Sophie, Blanc, Sébastien
Published in Journal of medicinal chemistry (09.04.2015)
Published in Journal of medicinal chemistry (09.04.2015)
Get full text
Journal Article