Next-generation spirobenzazepines : Identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies
XIANG, Min Amy, RYBCZYNSKI, Philip J, ZHONG, H. Marion, VILLANI, Frank J, DEMAREST, Keith T, DAMIANO, Bruce P, MARYANOFF, Bruce E, PATEL, Mona, CHEN, Robert H, MCCOMSEY, David F, ZHANG, Han-Cheng, GUNNET, Joseph W, LOOK, Richard, YUANPING WANG, MINOR, Lisa K
Published in Bioorganic & medicinal chemistry letters (01.12.2007)
Published in Bioorganic & medicinal chemistry letters (01.12.2007)
Get full text
Journal Article
Application of Microreactor Technology in Process Development
Zhang, Xini, Stefanick, Stephen, Villani, Frank J.
Published in Organic process research & development (01.05.2004)
Published in Organic process research & development (01.05.2004)
Get full text
Journal Article
Methodology for the Preparation of 2-Argininylbenzothiazole
Kenney, Birdella D, Breslav, Michael, Chang, Rosie, Glaser, Roland, Harris, Bruce D, Maryanoff, Cynthia A, Mills, John, Roessler, Armin, Segmuller, Brigitte, Villani, Frank J
Published in Journal of organic chemistry (07.12.2007)
Published in Journal of organic chemistry (07.12.2007)
Get full text
Journal Article
An efficient stereoselective synthesis of methyl ( S)-3-amino-3-(3-pyridyl)propanoate
Marlon Zhong, H, Cohen, Judith H, Abdel-Magid, Ahmed F, Kenney, Birdella D, Maryanoff, Cynthia A, Shah, Rekha D, Villani, Frank J, Zhang, Fan, Zhang, Xini
Published in Tetrahedron letters (29.10.1999)
Published in Tetrahedron letters (29.10.1999)
Get full text
Journal Article
Improved and Practical Synthesis of 6-Methoxy-1,2,3,4- tetrahydroisoquinoline Hydrochloride
Zhong, H. Marlon, Villani, Frank J, Marzouq, Ramzy
Published in Organic process research & development (01.05.2007)
Published in Organic process research & development (01.05.2007)
Get full text
Journal Article
NOVEL CRYSTALS AND PRODUCTION PROCESSES 5-({[2-AMINO-3-(4-CARBAMOYL-2,6-DIMETHYL-PHENYL)-PROPIONYL]-[1-(4-PHENYL-1H-IMIDAZOL-2-YL)-ETHYL]-AMINO}-METHYL)-2-METHOXY-BENZOIC ACID
FRANK J VILLANI, CHRISTOPHER ALLAN TELEHA, BARRY FEGELY, LUIGI ANZALONE, PENINA FEIBUSH
Year of Publication 09.08.2018
Get full text
Year of Publication 09.08.2018
Patent
NEW CRYSTALS AND METHODS OF MAKING 5-({[2-AMINO-3-(4-CARBAMOYL-2,6-DIMETHYL-PHENYL)-PROPIONYL]-[1-(4-PHENYL-1H-IMIDAZOL-2-YL)-ETHYL]-AMINO}-METHYL)-2-METHOXY-BENZOIC ACID
FRANK J VILLANI, CHRISTOPHER ALLAN TELEHA, BARRY FEGELY, LUIGI ANZALONE, PENINA FEIBUSH
Year of Publication 14.07.2016
Get full text
Year of Publication 14.07.2016
Patent
A Practical Synthesis of the Platelet Fibrinogen Antagonist, Elarofiban
Cohen, Judith H, Bos, Mary Ellen, Cesco-Cancian, Sergio, Harris, Bruce D, Hortenstine, John T, Justus, Michael, Maryanoff, Cynthia A, Mills, John, Muller, Stefan, Roessler, Armin, Scott, Lorraine, Sorgi, Kirk L, Villani, Frank J, Webster, Robin R. H, Weh, Christian
Published in Organic process research & development (01.11.2003)
Published in Organic process research & development (01.11.2003)
Get full text
Journal Article
NOVEL CRYSTALS AND PROCESS OF MAKING 5-({[2-AMINO-3-(4-CARBAMOYL-2,6-DIMETHYL-PHENYL)-PROPIONYL]-[1-(4-PHENYL-1H-IMIDAZOL-2-YL)-ETHYL]-AMINO}-METHYL)-2-METHOXY-BENZOIC ACID
FRANK J VILLANI, CHRISTOPHER ALLAN TELEHA, BARRY FEGELY, LUIGI ANZALONE, PENINA FEIBUSH
Year of Publication 16.07.2015
Get full text
Year of Publication 16.07.2015
Patent
An Expedient Method for Resolution of 3-Amino-3-(3‘-pyridyl)propionic Acid and Related Compounds
Boesch, Heinz, Cesco-Cancian, Sergio, Hecker, Leonard R, Hoekstra, William J, Justus, Michael, Maryanoff, Cynthia A, Scott, Lorraine, Shah, Rekha D, Solms, Guenter, Sorgi, Kirk L, Stefanick, Stephen M, Thurnheer, Urs, Villani, Frank J, Walker, Donald G
Published in Organic process research & development (01.01.2001)
Published in Organic process research & development (01.01.2001)
Get full text
Journal Article
Synthesis of amicetose by three enantioselective methods
Noecker, Lincoln A, Martino, Joseph A, Foley, Paul J, Rush, Diane M, Giuliano, Robert M, Villani, Frank J
Published in Tetrahedron: asymmetry (30.01.1998)
Published in Tetrahedron: asymmetry (30.01.1998)
Get full text
Journal Article
Process Research for the Synthesis of RWJ-51204, A Novel Anxiolytic Agent
Cohen, Judith H, Maryanoff, Cynthia A, Stefanick, Stephen M, Sorgi, Kirk L, Villani, Frank J
Published in Organic process research & development (01.07.1999)
Published in Organic process research & development (01.07.1999)
Get full text
Journal Article
First, Second, and Third Generation Scalable Syntheses of Two Potent H 3 Antagonists
Pippel, Daniel J., Mills, John E., Pandit, Chennagiri R., Young, Lana K., Zhong, Hua M., Villani, Frank J., Mani, Neelakandha S.
Published in Organic process research & development (20.05.2011)
Published in Organic process research & development (20.05.2011)
Get full text
Journal Article
A New Class of Hypnotics. Unsaturated Carbinols.1 Part I
Papa, Domenick, Villani, Frank J, Ginsberg, Helen F
Published in Journal of the American Chemical Society (01.09.1954)
Published in Journal of the American Chemical Society (01.09.1954)
Get full text
Journal Article
Next-generation spirobenzazepines: Identification of RWJ-676070 as a balanced vasopressin V 1a/V 2 receptor antagonist for human clinical studies
Xiang, Min Amy, Rybczynski, Philip J., Patel, Mona, Chen, Robert H., McComsey, David F., Zhang, Han-Cheng, Gunnet, Joseph W., Look, Richard, Wang, Yuanping, Minor, Lisa K., Zhong, H. Marlon, Villani, Frank J., Demarest, Keith T., Damiano, Bruce P., Maryanoff, Bruce E.
Published in Bioorganic & medicinal chemistry letters (01.12.2007)
Published in Bioorganic & medicinal chemistry letters (01.12.2007)
Get full text
Journal Article