Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology
Get full text
Book Review
Journal Article
Increasing fatty acid oxidation remodels the hypothalamic neurometabolome to mitigate stress and inflammation
McFadden, Joseph W, Aja, Susan, Li, Qun, Bandaru, Veera V R, Kim, Eun-Kyoung, Haughey, Norman J, Kuhajda, Francis P, Ronnett, Gabriele V
Published in PloS one (26.12.2014)
Published in PloS one (26.12.2014)
Get full text
Journal Article
Inhibiting Fatty Acid Synthase for Chemoprevention of Chemically Induced Lung Tumors
ORITA, Hajime, COULTER, Jonathan, TULLY, Ellen, KUHAJDA, Francis P, GABRIELSON, Edward
Published in Clinical cancer research (15.04.2008)
Published in Clinical cancer research (15.04.2008)
Get full text
Journal Article
C75, a Fatty Acid Synthase Inhibitor, Reduces Food Intake via Hypothalamic AMP-activated Protein Kinase
Kim, Eun-Kyoung, Miller, Ian, Aja, Susan, Landree, Leslie E, Pinn, Michael, McFadden, Jill, Kuhajda, Francis P, Moran, Timothy H, Ronnett, Gabriele V
Published in The Journal of biological chemistry (07.05.2004)
Published in The Journal of biological chemistry (07.05.2004)
Get full text
Journal Article
Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells
WEIBO ZHOU, WAN FANG HAN, RONNETT, Gabriele V, TOWNSEND, Craig A, KUHAJDA, Francis P, LANDREE, Leslie E, THUPARI, Jagan N, PINN, Michael L, BILILIGN, Tsion, EUN KYOUNG KIM, VADLAMUDI, Aravinda, MEDGHALCHI, Susan M, EL MESKINI, Rajaa
Published in Cancer research (Chicago, Ill.) (01.04.2007)
Published in Cancer research (Chicago, Ill.) (01.04.2007)
Get full text
Journal Article
Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells
HUI QIN WANG, ALTOMARE, Deborah A, SKELE, Kristine L, POULIKAKOS, Poulikos I, KUHAJDA, Francis P, DI CRISTOFANO, Antonio, TESTA, Joseph R
Published in Oncogene (19.05.2005)
Published in Oncogene (19.05.2005)
Get full text
Journal Article
Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity
Kuhajda, Francis P, Aja, Susan, Tu, Yajun, Han, Wan Fang, Medghalchi, Susan M, El Meskini, Rajaa, Landree, Leslie E, Peterson, Jonathan M, Daniels, Khadija, Wong, Kody, Wydysh, Edward A, Townsend, Craig A, Ronnett, Gabriele V
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.07.2011)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.07.2011)
Get full text
Journal Article
C75, a Fatty Acid Synthase Inhibitor, Modulates AMP-activated Protein Kinase to Alter Neuronal Energy Metabolism
Landree, Leslie E, Hanlon, Andrea L, Strong, David W, Rumbaugh, Gavin, Miller, Ian M, Thupari, Jagan N, Connolly, Erin C, Huganir, Richard L, Richardson, Christine, Witters, Lee A, Kuhajda, Francis P, Ronnett, Gabriele V
Published in The Journal of biological chemistry (30.01.2004)
Published in The Journal of biological chemistry (30.01.2004)
Get full text
Journal Article
Chronic C75 treatment of diet-induced obese mice increases fat oxidation and reduces food intake to reduce adipose mass
Thupari, Jagan N, Kim, Eun-Kyoung, Moran, Timothy H, Ronnett, Gabriele V, Kuhajda, Francis P
Published in American journal of physiology: endocrinology and metabolism (01.07.2004)
Published in American journal of physiology: endocrinology and metabolism (01.07.2004)
Get full text
Journal Article
Application of a Flexible Synthesis of (5R)-Thiolactomycin To Develop New Inhibitors of Type I Fatty Acid Synthase
McFadden, Jill M, Medghalchi, Susan M, Thupari, Jagan N, Pinn, Michael L, Vadlamudi, Aravinda, Miller, Katherine I, Kuhajda, Francis P, Townsend, Craig A
Published in Journal of medicinal chemistry (24.02.2005)
Published in Journal of medicinal chemistry (24.02.2005)
Get full text
Journal Article
Expression of FAS within hypothalamic neurons: a model for decreased food intake after C75 treatment
Kim, Eun-Kyoung, Miller, Ian, Landree, Leslie E, Borisy-Rudin, Felice F, Brown, Pierre, Tihan, Tarik, Townsend, Craig A, Witters, Lee A, Moran, Timothy H, Kuhajda, Francis P, Ronnett, Gabriele V
Published in American journal of physiology: endocrinology and metabolism (01.11.2002)
Published in American journal of physiology: endocrinology and metabolism (01.11.2002)
Get full text
Journal Article
C75 Alters Central and Peripheral Gene Expression to Reduce Food Intake and Increase Energy Expenditure
Tu, Yajun, Thupari, Jagan N, Kim, Eun-Kyoung, Pinn, Michael L, Moran, Timothy H, Ronnett, Gabriele V, Kuhajda, Francis P
Published in Endocrinology (Philadelphia) (01.01.2005)
Published in Endocrinology (Philadelphia) (01.01.2005)
Get full text
Journal Article
Increased Fatty Acid Synthase is a Therapeutic Target in Mesothelioma
GABRIELSON, Edward W, PINN, Michael L, TESTA, Joseph R, KUHAJDA, Francis P
Published in Clinical cancer research (01.01.2001)
Get full text
Published in Clinical cancer research (01.01.2001)
Journal Article
The connections between C75 and obesity drug-target pathways
Kuhajda, Francis P., Landree, Leslie E., Ronnett, Gabriele V.
Published in Trends in pharmacological sciences (Regular ed.) (01.11.2005)
Published in Trends in pharmacological sciences (Regular ed.) (01.11.2005)
Get full text
Journal Article
Intracerebroventricular C75 decreases meal frequency and reduces AgRP gene expression in rats
Aja, Susan, Bi, Sheng, Knipp, Susan B, McFadden, Jill M, Ronnett, Gabriele V, Kuhajda, Francis P, Moran, Timothy H
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.07.2006)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.07.2006)
Get full text
Journal Article
Fatty acid synthase (FAS) expression in human breast cancer cell culture supernatants and in breast cancer patients
Wang, Young (Yongqiang), Kuhajda, Francis P., Li, Ji Nong, Pizer, Ellen S., Han, Wan Fang, Sokoll, Lori J., Chan, Daniel W.
Published in Cancer letters (10.06.2001)
Published in Cancer letters (10.06.2001)
Get full text
Journal Article