5'-Chloro-5'-deoxy-(±)-ENBA, a Potent and Selective Adenosine A1 Receptor Agonist, Alleviates Neuropathic Pain in Mice Through Functional Glial and Microglial Changes without Affecting Motor or Cardiovascular Functions
Luongo, Livio, Petrelli, Riccardo, Gatta, Luisa, Giordano, Catia, Guida, Francesca, Vita, Patrizia, Franchetti, Palmarisa, Grifantini, Mario, Novellis, Vito de, Cappellacci, Loredana, Maione, Sabatino
Published in Molecules (Basel, Switzerland) (01.12.2012)
Published in Molecules (Basel, Switzerland) (01.12.2012)
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Novel inhibitors of inosine monophosphate dehydrogenase in patent literature of the last decade
Petrelli, Riccardo, Vita, Patrizia, Torquati, Ilaria, Felczak, Krzysztof, Wilson, Daniel J, Franchetti, Palmarisa, Cappellacci, Loredana
Published in Recent patents on anti-cancer drug discovery (01.05.2013)
Published in Recent patents on anti-cancer drug discovery (01.05.2013)
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5 '-C-Ethyl-tetrazolyl-N-6-Substituted Adenosine and 2-Chloro-adenosine Derivatives as Highly Potent Dual Acting A(1) Adenosine Receptor Agonists and A(3) Adenosine Receptor Antagonists
Petrelli, Riccardo, Torquati, Ilaria, Kachler, Sonja, Luongo, Livio, Maione, Sabatino, Franchetti, Palmarisa, Grifantini, Mario, Novellino, Ettore, Lavecchia, Antonio, Klotz, Karl-Norbert, Cappellacci, Loredana
Published in Journal of medicinal chemistry (12.03.2015)
Published in Journal of medicinal chemistry (12.03.2015)
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Initial-Rate Kinetics of Human NMN-Adenylyltransferases: Substrate and Metal Ion Specificity, Inhibition by Products and Multisubstrate Analogues, and Isozyme Contributions to NAD+ Biosynthesis
Sorci, Leonardo, Cimadamore, Flavio, Scotti, Stefania, Petrelli, Riccardo, Cappellacci, Loredana, Franchetti, Palmarisa, Orsomando, Giuseppe, Magni, Giulio
Published in Biochemistry (Easton) (24.04.2007)
Published in Biochemistry (Easton) (24.04.2007)
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5'-C-Ethyl-tetrazolyl-N(6)-substituted adenosine and 2-chloro-adenosine derivatives as highly potent dual acting A1 adenosine receptor agonists and A3 adenosine receptor antagonists
Petrelli, Riccardo, Torquati, Ilaria, Kachler, Sonja, Luongo, Livio, Maione, Sabatino, Franchetti, Palmarisa, Grifantini, Mario, Novellino, Ettore, Lavecchia, Antonio, Klotz, Karl-Norbert, Cappellacci, Loredana
Published in Journal of medicinal chemistry (12.03.2015)
Published in Journal of medicinal chemistry (12.03.2015)
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N-6-Cycloalkyl- and N-6-Bicycloalkyl-C5 '(C2 ')-modified Adenosine Derivatives as High-Affinity and Selective Agonists at the Human A(1) Adenosine Receptor with Antinociceptive Effects in Mice
Franchetti, Palmarisa, Cappellacci, Loredana, Vita, Patrizia, Petrelli, Riccardo, Lavecchia, Antonio, Kachler, Sonja, Klotz, Karl-Norbert, Marabese, Ida, Luongo, Livio, Maione, Sabatino, Grifantini, Mario
Published in Journal of medicinal chemistry (23.04.2009)
Published in Journal of medicinal chemistry (23.04.2009)
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5′- C -Ethyl-tetrazolyl- N 6 -Substituted Adenosine and 2-Chloro-adenosine Derivatives as Highly Potent Dual Acting A 1 Adenosine Receptor Agonists and A 3 Adenosine Receptor Antagonists
Petrelli, Riccardo, Torquati, Ilaria, Kachler, Sonja, Luongo, Livio, Maione, Sabatino, Franchetti, Palmarisa, Grifantini, Mario, Novellino, Ettore, Lavecchia, Antonio, Klotz, Karl-Norbert, Cappellacci, Loredana
Published in Journal of medicinal chemistry (12.03.2015)
Published in Journal of medicinal chemistry (12.03.2015)
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From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: Synthesis and biological evaluation of valproic esters of 3′-C-methyladenosine
Petrelli, Riccardo, Meli, Maria, Vita, Patrizia, Torquati, Ilaria, Ferro, Arianna, Vodnala, Munender, D’Alessandro, Natale, Tolomeo, Manlio, Del Bello, Fabio, Kusumanchi, Praveen, Franchetti, Palmarisa, Grifantini, Mario, Jayaram, Hiremagalur N., Hofer, Anders, Cappellacci, Loredana
Published in Bioorganic & medicinal chemistry letters (15.11.2014)
Published in Bioorganic & medicinal chemistry letters (15.11.2014)
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Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists
KO, Hyojin, CARTER, Rhonda L, VAN CALENBERGH, Serge, HARDEN, T. Kendall, JACOBSON, Kenneth A, COSYN, Liesbet, PETRELLI, Riccardo, DE CASTRO, Sonia, BESADA, Pedro, YIXING ZHOU, CAPPELLACCI, Loredana, FRANCHETTI, Palmarisa, GRIFANTINI, Mario
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Synthesis and biological activity of novel N 6-substituted and 2, N 6-disubstituted adenine ribo- and 3′- C-methyl-ribonucleosides as antitumor agents
Cappellacci, Loredana, Petrelli, Riccardo, Franchetti, Palmarisa, Vita, Patrizia, Kusumanchi, Praveen, Kumar, Mohineesh, Jayaram, Hiremagalur N., Zhou, Bingsen, Yen, Yun, Grifantini, Mario
Published in European journal of medicinal chemistry (01.05.2011)
Published in European journal of medicinal chemistry (01.05.2011)
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5'-Chloro-5'-deoxy-(±)-ENBA, a potent and selective adenosine A(1) receptor agonist, alleviates neuropathic pain in mice through functional glial and microglial changes without affecting motor or cardiovascular functions
Luongo, Livio, Petrelli, Riccardo, Gatta, Luisa, Giordano, Catia, Guida, Francesca, Vita, Patrizia, Franchetti, Palmarisa, Grifantini, Mario, de Novellis, Vito, Cappellacci, Loredana, Maione, Sabatino
Published in Molecules (Basel, Switzerland) (22.11.2012)
Published in Molecules (Basel, Switzerland) (22.11.2012)
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Adenosine deaminase inhibitors: synthesis and structure activity relationships of imidazole analogs of erythro-9-(2-hydroxy-3-nonyl)adenine
Cristalli, Gloria, Eleuteri, Alessandra, Franchetti, Palmarisa, Grifantini, Mario, Vittori, Sauro, Lupidi, Giulio
Published in Journal of medicinal chemistry (01.03.1991)
Published in Journal of medicinal chemistry (01.03.1991)
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Ribose-Modified Purine Nucleosides as Ribonucleotide Reductase Inhibitors. Synthesis, Antitumor Activity, and Molecular Modeling of N 6-Substituted 3′-C-Methyladenosine Derivatives
Cappellacci, Loredana, Franchetti, Palmarisa, Vita, Patrizia, Petrelli, Riccardo, Lavecchia, Antonio, Jayaram, Hiremagalur N, Saiko, Philipp, Graser, Geraldine, Szekeres, Thomas, Grifantini, Mario
Published in Journal of medicinal chemistry (24.07.2008)
Published in Journal of medicinal chemistry (24.07.2008)
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5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists : Affinity, efficacy, and selectivity for A1 receptor from different species
CAPPELLACCI, Loredana, FRANCHETTI, Palmarisa, VITA, Patrizia, PETRELLI, Riccardo, LAVECCHIA, Antonio, COSTA, Barbara, SPINETTI, Francesca, MARTINI, Claudia, KLOTZ, Karl-Norbert, GRIFANTINI, Mario
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues
Petrelli, Riccardo, Sham, Yuk Yin, Chen, Liqiang, Felczak, Krzysztof, Bennett, Eric, Wilson, Daniel, Aldrich, Courtney, Yu, Jose S., Cappellacci, Loredana, Franchetti, Palmarisa, Grifantini, Mario, Mazzola, Francesca, Di Stefano, Michele, Magni, Giulio, Pankiewicz, Krzysztof W.
Published in Bioorganic & medicinal chemistry (01.08.2009)
Published in Bioorganic & medicinal chemistry (01.08.2009)
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Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents
CAPPELLACCI, Loredana, PETRELLI, Riccardo, FRANCHETTI, Palmarisa, VITA, Patrizia, KUSUMANCHI, Praveen, KUMAR, Mohineesh, JAYARAM, Hiremagalur N, BINGSEN ZHOU, YUN YEN, GRIFANTINI, Mario
Published in European journal of medicinal chemistry (01.05.2011)
Published in European journal of medicinal chemistry (01.05.2011)
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N 6 -Cycloalkyl- and N 6 -Bicycloalkyl- C 5′( C 2′)-modified Adenosine Derivatives as High-Affinity and Selective Agonists at the Human A 1 Adenosine Receptor with Antinociceptive Effects in Mice
Franchetti, Palmarisa, Cappellacci, Loredana, Vita, Patrizia, Petrelli, Riccardo, Lavecchia, Antonio, Kachler, Sonja, Klotz, Karl-Norbert, Marabese, Ida, Luongo, Livio, Maione, Sabatino, Grifantini, Mario
Published in Journal of medicinal chemistry (28.05.2009)
Published in Journal of medicinal chemistry (28.05.2009)
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N6-Cycloalkyl-and N6-Bicycloalkyl-C5'(C2')-modified Adenosine Derivatives as High-Affinity and Selective Agonists at the Human A1 Adenosine Receptor with Antinociceptive Effects in Mice
FRANCHETTI, Palmarisa, CAPPELLACCI, Loredana, GRIFANTINI, Mario, VITA, Patrizia, PETRELLI, Riccardo, LAVECCHIA, Antonio, KACHLER, Sonja, KLOTZ, Karl-Norbert, MARABESE, Ida, LUONGO, Livio, MAIONE, Sabatino
Published in Journal of medicinal chemistry (23.04.2009)
Published in Journal of medicinal chemistry (23.04.2009)
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Journal Article
N 6 -Cycloalkyl- and N 6 -Bicycloalkyl- C 5′( C 2′)-modified Adenosine Derivatives as High-Affinity and Selective Agonists at the Human A 1 Adenosine Receptor with Antinociceptive Effects in Mice
Franchetti, Palmarisa, Cappellacci, Loredana, Vita, Patrizia, Petrelli, Riccardo, Lavecchia, Antonio, Kachler, Sonja, Klotz, Karl-Norbert, Marabese, Ida, Luongo, Livio, Maione, Sabatino, Grifantini, Mario
Published in Journal of medicinal chemistry (23.04.2009)
Published in Journal of medicinal chemistry (23.04.2009)
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