Hyaluronan synthesis and degradation in cartilage and bone
Bastow, E. R, Byers, S, Golub, S. B, Clarkin, C. E, Pitsillides, A. A, Fosang, A. J
Published in Cellular and molecular life sciences : CMLS (01.02.2008)
Published in Cellular and molecular life sciences : CMLS (01.02.2008)
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ADAMTS-5: the story so far
Fosang, A J, Rogerson, F M, East, C J, Stanton, H
Published in European cells & materials (05.02.2008)
Published in European cells & materials (05.02.2008)
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The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases, and cathepsin B
FOSANG, A. J, NEAME, P. J, LAST, K, HARDINGHAM, T. E, MURPHY, G, HAMILTON, J. A
Published in The Journal of biological chemistry (25.09.1992)
Published in The Journal of biological chemistry (25.09.1992)
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Matrix metalloproteinase 13–deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development
Little, C. B., Barai, A., Burkhardt, D., Smith, S. M., Fosang, A. J., Werb, Z., Shah, M., Thompson, E. W.
Published in Arthritis and rheumatism (01.12.2009)
Published in Arthritis and rheumatism (01.12.2009)
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Disrupted type II collagenolysis impairs angiogenesis, delays endochondral ossification and initiates aberrant ossification in mouse limbs
Gauci, S.J., Golub, S.B., Tatarczuch, L., Lee, E., Chan, D., Walsh, N.C., Little, C.B., Stanton, H., Lokmic, Z., Sims, N.A., Mackie, E.J., Fosang, A.J.
Published in Matrix biology (01.10.2019)
Published in Matrix biology (01.10.2019)
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Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domain
FOSANG, A. J, LAST, K, KNÄUPER, V, NEAME, P. J, MURPHY, G, HARDINGHAM, T. E, TSCHESCHE, H, HAMILTON, J. A
Published in Biochemical journal (01.10.1993)
Published in Biochemical journal (01.10.1993)
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Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro
Hughes, C E, Caterson, B, Fosang, A J, Roughley, P J, Mort, J S
Published in Biochemical journal (01.02.1995)
Published in Biochemical journal (01.02.1995)
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Journal Article
Generation and Novel Distribution of Matrix Metalloproteinase-derived Aggrecan Fragments in Porcine Cartilage Explants
Fosang, Amanda J., Last, Karena, Stanton, Heather, Weeks, David B., Campbell, Ian K., Hardingham, Timothy E., Hembry, Rosalind M.
Published in The Journal of biological chemistry (20.10.2000)
Published in The Journal of biological chemistry (20.10.2000)
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Mutations in the interglobular domain of aggrecan alter matrix metalloproteinase and aggrecanase cleavage patterns. Evidence that matrix metalloproteinase cleavage interferes with aggrecanase activity
Mercuri, F A, Maciewicz, R A, Tart, J, Last, K, Fosang, A J
Published in The Journal of biological chemistry (20.10.2000)
Published in The Journal of biological chemistry (20.10.2000)
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Journal Article
Cleavage of cartilage proteoglycan between G1 and G2 domains by stromelysins
FOSANG, A. J, NEAME, P. J, HARDINGHAM, T. E, MURPHY, G, HAMILTON, J. A
Published in The Journal of biological chemistry (25.08.1991)
Published in The Journal of biological chemistry (25.08.1991)
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Development of a cleavage-site-specific monoclonal antibody for detecting metalloproteinase-derived aggrecan fragments: detection of fragments in human synovial fluids
Fosang, A J, Last, K, Gardiner, P, Jackson, D C, Brown, L
Published in Biochemical journal (15.08.1995)
Published in Biochemical journal (15.08.1995)
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Increased hyaluronan production in the glomeruli from diabetic rats: a link between glucose-induced prostaglandin production and reduced sulphated proteoglycan
Mahadevan, P, Larkins, R G, Fraser, J R, Fosang, A J, Dunlop, M E
Published in Diabetologia (01.03.1995)
Published in Diabetologia (01.03.1995)
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MMP and non-MMP-mediated release of aggrecan and its fragments from articular cartilage: a comparative study of three different aggrecan and glycosaminoglycan assays
Sumer, E.U., M.Sc, Sondergaard, B.C., M.Sc, Rousseau, J.C., Ph.D, Delmas, P.D., M.D., Ph.D, Fosang, A.J., Ph.D, Karsdal, M.A., Ph.D, Christiansen, C., D.M.Sc, Qvist, P., Ph.D
Published in Osteoarthritis and cartilage (01.02.2007)
Published in Osteoarthritis and cartilage (01.02.2007)
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