Interferon Gamma Enhances Cytoprotective Pathways via Nrf2 and MnSOD Induction in Friedreich’s Ataxia Cells
Luffarelli, Riccardo, Panarello, Luca, Quatrana, Andrea, Tiano, Francesca, Fortuni, Silvia, Rufini, Alessandra, Malisan, Florence, Testi, Roberto, Condò, Ivano
Published in International journal of molecular sciences (01.08.2023)
Published in International journal of molecular sciences (01.08.2023)
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Modelling the Human Blood–Brain Barrier in Huntington Disease
Vignone, Domenico, Gonzalez Paz, Odalys, Fini, Ivan, Cellucci, Antonella, Auciello, Giulio, Battista, Maria Rosaria, Gloaguen, Isabelle, Fortuni, Silvia, Cariulo, Cristina, Khetarpal, Vinod, Dominguez, Celia, Muñoz-Sanjuán, Ignacio, Di Marco, Annalise
Published in International journal of molecular sciences (15.07.2022)
Published in International journal of molecular sciences (15.07.2022)
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E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia
Benini, Monica, Fortuni, Silvia, Condò, Ivano, Alfedi, Giulia, Malisan, Florence, Toschi, Nicola, Serio, Dario, Massaro, Damiano Sergio, Arcuri, Gaetano, Testi, Roberto, Rufini, Alessandra
Published in Cell reports (Cambridge) (21.02.2017)
Published in Cell reports (Cambridge) (21.02.2017)
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Highly specific ubiquitin-competing molecules effectively promote frataxin accumulation and partially rescue the aconitase defect in Friedreich ataxia cells
Rufini, Alessandra, Cavallo, Francesca, Condò, Ivano, Fortuni, Silvia, De Martino, Gabriella, Incani, Ottaviano, Di Venere, Almerinda, Benini, Monica, Massaro, Damiano Sergio, Arcuri, Gaetano, Serio, Dario, Malisan, Florence, Testi, Roberto
Published in Neurobiology of disease (01.03.2015)
Published in Neurobiology of disease (01.03.2015)
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SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia
Bon, Carlotta, Luffarelli, Riccardo, Russo, Roberta, Fortuni, Silvia, Pierattini, Bianca, Santulli, Chiara, Fimiani, Cristina, Persichetti, Francesca, Cotella, Diego, Mallamaci, Antonello, Santoro, Claudio, Carninci, Piero, Espinoza, Stefano, Testi, Roberto, Zucchelli, Silvia, Condò, Ivano, Gustincich, Stefano
Published in Nucleic acids research (18.11.2019)
Published in Nucleic acids research (18.11.2019)
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Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia
Alfedi, Giulia, Luffarelli, Riccardo, Condò, Ivano, Pedini, Giorgia, Mannucci, Liliana, Massaro, Damiano S., Benini, Monica, Toschi, Nicola, Alaimo, Giorgia, Panarello, Luca, Pacini, Laura, Fortuni, Silvia, Serio, Dario, Malisan, Florence, Testi, Roberto, Rufini, Alessandra
Published in Movement disorders (01.03.2019)
Published in Movement disorders (01.03.2019)
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Safety and efficacy of interferon γ in friedreich's ataxia
Vavla, Marinela, D'Angelo, Maria Grazia, Arrigoni, Filippo, Toschi, Nicola, Peruzzo, Denis, Gandossini, Sandra, Russo, Annamaria, Diella, Eleonora, Tirelli, Stefania, Salati, Roberto, Scarpazza, Paolo, Luffarelli, Riccardo, Fortuni, Silvia, Rufini, Alessandra, Condò, Ivano, Testi, Roberto, Martinuzzi, Andrea
Published in Movement disorders (01.02.2020)
Published in Movement disorders (01.02.2020)
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Frataxin deficiency in Friedreich’s ataxia is associated with reduced levels of HAX-1, a regulator of cardiomyocyte death and survival
Tiano, Francesca, Amati, Francesca, Cherubini, Fabio, Morini, Elena, Vancheri, Chiara, Maletta, Sara, Fortuni, Silvia, Serio, Dario, Quatrana, Andrea, Luffarelli, Riccardo, Benini, Monica, Alfedi, Giulia, Panarello, Luca, Rufini, Alessandra, Toschi, Nicola, Frontali, Marina, Romano, Silvia, Marcotulli, Christian, Casali, Carlo, Gioiosa, Silvia, Mariotti, Caterina, Mongelli, Alessia, Fichera, Mario, Condò, Ivano, Novelli, Giuseppe, Testi, Roberto, Malisan, Florence
Published in Human molecular genetics (01.02.2020)
Published in Human molecular genetics (01.02.2020)
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Src inhibitors modulate frataxin protein levels
Cherubini, Fabio, Serio, Dario, Guccini, Ilaria, Fortuni, Silvia, Arcuri, Gaetano, Condò, Ivano, Rufini, Alessandra, Moiz, Shadman, Camerini, Serena, Crescenzi, Marco, Testi, Roberto, Malisan, Florence
Published in Human molecular genetics (01.08.2015)
Published in Human molecular genetics (01.08.2015)
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Preventing the ubiquitin―proteasome-dependent degradation of frataxin, the protein defective in Friedreich's ataxia
RUFINI, Alessandra, FORTUNI, Silvia, ARCURI, Gaetano, CONDO, Ivano, SERIO, Dario, INCANI, Ottaviano, MALISAN, Florence, VENTURA, Natascia, TESTI, Roberto
Published in Human molecular genetics (01.04.2011)
Published in Human molecular genetics (01.04.2011)
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GIFT-1, a phase IIa clinical trial to test the safety and efficacy of IFNγ administration in FRDA patients
Marcotulli, Christian, Fortuni, Silvia, Arcuri, Gaetano, Tomassini, Barbara, Leonardi, Luca, Pierelli, Francesco, Testi, Roberto, Casali, Carlo
Published in Neurological sciences (01.03.2016)
Published in Neurological sciences (01.03.2016)
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Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model
TOMASSINI, Barbara, ARCURI, Gaetano, TESTI, Roberto, FORTUNI, Silvia, SANDI, Chiranjeevi, EZZATIZADEH, Vahid, CASALI, Carlo, CONDO, Ivano, MALISAN, Florence, AL-MAHDAWI, Sahar, POOK, Mark
Published in Human molecular genetics (01.07.2012)
Published in Human molecular genetics (01.07.2012)
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Analyzing the Effects of a G137V Mutation in the FXN Gene
Faggianelli, Nathalie, Puglisi, Rita, Veneziano, Liana, Romano, Silvia, Frontali, Marina, Vannocci, Tommaso, Fortuni, Silvia, Testi, Roberto, Pastore, Annalisa
Published in Frontiers in molecular neuroscience (25.11.2015)
Published in Frontiers in molecular neuroscience (25.11.2015)
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