Etoricoxib (MK-0663): Preclinical Profile and Comparison with Other Agents That Selectively Inhibit Cyclooxygenase-2
Riendeau, D, Percival, M D, Brideau, C, Charleson, S, Dubé, D, Ethier, D, Falgueyret, J P, Friesen, R W, Gordon, R, Greig, G, Guay, J, Mancini, J, Ouellet, M, Wong, E, Xu, L, Boyce, S, Visco, D, Girard, Y, Prasit, P, Zamboni, R, Rodger, I W, Gresser, M, Ford-Hutchinson, A W, Young, R N, Chan, C C
Published in The Journal of pharmacology and experimental therapeutics (01.02.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.02.2001)
Journal Article
Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX‐2 inhibitor
Riendeau, D, Percival, M D, Boyce, S, Brideau, C, Charleson, S, Cromlish, W, Ethier, D, Evans, J, Falgueyret, J ‐P, Ford‐Hutchinson, A W, Gordon, R, Greig, G, Gresser, M, Guay, J, Kargman, S, Léger, S, Mancini, J A, O'Neill, G, Ouellet, M, Rodger, I W, Thérien, M, Wang, Z, Webb, J K, Wong, E, Xu, L, Young, R N, Zamboni, R, Prasit, P, Chan, C ‐C
Published in British journal of pharmacology (01.05.1997)
Published in British journal of pharmacology (01.05.1997)
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Journal Article
Rofecoxib [Vioxx, MK-0966; 4-(4â²-Methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: A Potent and Orally Active Cyclooxygenase-2 Inhibitor. Pharmacological and Biochemical Profiles
Chan, C C, Boyce, S, Brideau, C, Charleson, S, Cromlish, W, Ethier, D, Evans, J, Ford-Hutchinson, A W, Forrest, M J, Gauthier, J Y, Gordon, R, Gresser, M, Guay, J, Kargman, S, Kennedy, B, Leblanc, Y, Leger, S, Mancini, J, O'Neill, G P, Ouellet, M, Patrick, D, Percival, M D, Perrier, H, Prasit, P, Rodger, I
Published in The Journal of pharmacology and experimental therapeutics (01.08.1999)
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Published in The Journal of pharmacology and experimental therapeutics (01.08.1999)
Journal Article
The discovery of rofecoxib, [MK 966, VIOXX ®, 4-(4′-methylsulfonylphenyl)-3-phenyl-2(5 H)-furanone], an orally active cyclooxygenase-2 inhibitor
Prasit, P, Wang, Z, Brideau, C, Chan, C.-C, Charleson, S, Cromlish, W, Ethier, D, Evans, J.F, Ford-Hutchinson, A.W, Gauthier, J.Y, Gordon, R, Guay, J, Gresser, M, Kargman, S, Kennedy, B, Leblanc, Y, Léger, S, Mancini, J, O'Neill, G.P, Ouellet, M, Percival, M.D, Perrier, H, Riendeau, D, Rodger, I, Tagari, P, Thérien, M, Vickers, P, Wong, E, Xu, L.-J, Young, R.N, Zamboni, R, Boyce, S, Rupniak, N, Forrest, M, Visco, D, Patrick, D
Published in Bioorganic & medicinal chemistry letters (05.07.1999)
Published in Bioorganic & medicinal chemistry letters (05.07.1999)
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Journal Article
Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach
Chan, C C, Boyce, S, Brideau, C, Ford-Hutchinson, A W, Gordon, R, Guay, D, Hill, R G, Li, C S, Mancini, J, Penneton, M
Published in The Journal of pharmacology and experimental therapeutics (01.09.1995)
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Published in The Journal of pharmacology and experimental therapeutics (01.09.1995)
Journal Article
Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist
Jones, T R, Zamboni, R, Belley, M, Champion, E, Charette, L, Ford-Hutchinson, A W, Frenette, R, Gauthier, J Y, Leger, S, Masson, P
Published in Canadian journal of physiology and pharmacology (01.01.1989)
Published in Canadian journal of physiology and pharmacology (01.01.1989)
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Journal Article
Pharmacology of montelukast sodium (Singulair), a potent and selective leukotriene D4 receptor antagonist
Jones, T R, Labelle, M, Belley, M, Champion, E, Charette, L, Evans, J, Ford-Hutchinson, A W, Gauthier, J Y, Lord, A, Masson, P
Published in Canadian journal of physiology and pharmacology (01.02.1995)
Published in Canadian journal of physiology and pharmacology (01.02.1995)
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Journal Article
Increased urinary LTE4 excretion following inhalation of LTC4 and LTE4 in asthmatic subjects
Christie, PE, Tagari, P, Ford-Hutchinson, AW, Black, C, Markendorf, A, Schmitz-Schumann, M, Lee, TH
Published in The European respiratory journal (01.05.1994)
Published in The European respiratory journal (01.05.1994)
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Journal Article
Stereospecific synthesis, assignment of absolute configuration, and biological activity of the enantiomers of 3-[[[3-[2-(7-chloroquinolin-2-yl)-(E)-ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid, a potent and specific leukotriene D4 receptor antagonist
Gauthier, J. Y, Jones, T, Champion, E, Charette, L, Dehaven, R, Ford-Hutchinson, A. W, Hoogsteen, K, Lord, A, Masson, P
Published in Journal of medicinal chemistry (01.10.1990)
Published in Journal of medicinal chemistry (01.10.1990)
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Journal Article
Characterization of the recombinant human prostanoid DP receptor and identification of L‐644,698, a novel selective DP agonist
Hamish Wright, D., Metters, Kathleen M., Abramovitz, Mark, Ford‐Hutchinson, Anthony W.
Published in British journal of pharmacology (01.04.1998)
Published in British journal of pharmacology (01.04.1998)
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Journal Article
Increased urinary leukotriene excretion in patients with cardiac ischemia : in vivo evidence for 5-lipoxygenase activation
CARRY, M, KORLEY, V, WIILERSON, J. T, WEIGELT, L, FORD-HUTCHINSON, A. W, TAGARI, P
Published in Circulation (New York, N.Y.) (1992)
Published in Circulation (New York, N.Y.) (1992)
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Conference Proceeding
Journal Article
Innovations in drug research: inhibitors of thromboxane and leukotrienes
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Journal Article
Conference Proceeding
L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2 - dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor
Gillard, J, Ford-Hutchinson, A W, Chan, C, Charleson, S, Denis, D, Foster, A, Fortin, R, Leger, S, McFarlane, C S, Morton, H
Published in Canadian journal of physiology and pharmacology (01.05.1989)
Published in Canadian journal of physiology and pharmacology (01.05.1989)
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Journal Article
BQ-153, a novel endothelin (ET)A antagonist, attenuates the renal vascular effects of endothelin-1
Cirino, M, Motz, C, Maw, J, Ford-Hutchinson, A W, Yano, M
Published in Journal of pharmacy and pharmacology (01.09.1992)
Published in Journal of pharmacy and pharmacology (01.09.1992)
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Journal Article
The role of arachidonic acid oxygenation products in pain and inflammation
Davies, P, Bailey, P J, Goldenberg, M M, Ford-Hutchinson, A W
Published in Annual review of immunology (01.04.1984)
Published in Annual review of immunology (01.04.1984)
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Journal Article
5-Lipoxygenase
Ford-Hutchinson, A W, Gresser, M, Young, R N
Published in Annual review of biochemistry (01.01.1994)
Published in Annual review of biochemistry (01.01.1994)
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Journal Article
Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes
Ford-Hutchinson, A W, Bray, M A, Doig, M V, Shipley, M E, Smith, M J
Published in Nature (London) (17.07.1980)
Published in Nature (London) (17.07.1980)
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