P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study
Abdulqawi, Rayid, PhD, Dockry, Rachel, MSc, Holt, Kimberley, BSc, Layton, Gary, MSc, McCarthy, Bruce G, MD, Ford, Anthony P, PhD, Smith, Jaclyn A, Prof
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Published in The Lancet (British edition) (28.03.2015)
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Transient receptor potential cation channel, subfamily V, member 4 and airway sensory afferent activation: Role of adenosine triphosphate
Bonvini, Sara J., PhD, Birrell, Mark A., PhD, Grace, Megan S., PhD, Maher, Sarah A., PhD, Adcock, John J., PhD, Wortley, Michael A., PhD, Dubuis, Eric, PhD, Ching, Yee-Man, MRes, Ford, Anthony P., PhD, Shala, Fisnik, MD, Miralpeix, Montserrat, PhD, Tarrason, Gema, PhD, Smith, Jaclyn A., PhD, Belvisi, Maria G., PhD
Published in Journal of allergy and clinical immunology (01.07.2016)
Published in Journal of allergy and clinical immunology (01.07.2016)
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The effect of gefapixant, a P2X3 antagonist, on cough reflex sensitivity: a randomised placebo-controlled study
Morice, Alyn H, Kitt, Michael M, Ford, Anthony P, Tershakovec, Andrew M, Wu, Wen-Chi, Brindle, Kayleigh, Thompson, Rachel, Thackray-Nocera, Susannah, Wright, Caroline
Published in The European respiratory journal (01.07.2019)
Published in The European respiratory journal (01.07.2019)
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Gefapixant in two randomised dose-escalation studies in chronic cough
Smith, Jaclyn A, Kitt, Michael M, Butera, Peter, Smith, Steven A, Li, Yuping, Xu, Zhi Jin, Holt, Kimberley, Sen, Shilpi, Sher, Mandel R, Ford, Anthony P
Published in The European respiratory journal (01.03.2020)
Published in The European respiratory journal (01.03.2020)
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Purinergic receptors in the carotid body as a new drug target for controlling hypertension
Pijacka, Wioletta, Moraes, Davi J A, Ratcliffe, Laura E K, Nightingale, Angus K, Hart, Emma C, da Silva, Melina P, Machado, Benedito H, McBryde, Fiona D, Abdala, Ana P, Ford, Anthony P, Paton, Julian F R
Published in Nature medicine (01.10.2016)
Published in Nature medicine (01.10.2016)
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Gut microbiome immaturity and childhood acute lymphoblastic leukaemia
Peppas, Ioannis, Ford, Anthony M., Furness, Caroline L., Greaves, Mel F.
Published in Nature reviews. Cancer (01.08.2023)
Published in Nature reviews. Cancer (01.08.2023)
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RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia
Papaemmanuil, Elli, Rapado, Inmaculada, Li, Yilong, Potter, Nicola E, Wedge, David C, Tubio, Jose, Alexandrov, Ludmil B, Van Loo, Peter, Cooke, Susanna L, Marshall, John, Martincorena, Inigo, Hinton, Jonathan, Gundem, Gunes, van Delft, Frederik W, Nik-Zainal, Serena, Jones, David R, Ramakrishna, Manasa, Titley, Ian, Stebbings, Lucy, Leroy, Catherine, Menzies, Andrew, Gamble, John, Robinson, Ben, Mudie, Laura, Raine, Keiran, O'Meara, Sarah, Teague, Jon W, Butler, Adam P, Cazzaniga, Giovanni, Biondi, Andrea, Zuna, Jan, Kempski, Helena, Muschen, Markus, Ford, Anthony M, Stratton, Michael R, Greaves, Mel, Campbell, Peter J
Published in Nature genetics (01.02.2014)
Published in Nature genetics (01.02.2014)
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AF‐353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist
Gever, Joel R, Soto, Rothschild, Henningsen, Robert A, Martin, Renee S, Hackos, David H, Panicker, Sandip, Rubas, Werner, Oglesby, Ian B, Dillon, Michael P, Milla, Marcos E, Burnstock, Geoffrey, Ford, Anthony PDW
Published in British journal of pharmacology (01.07.2010)
Published in British journal of pharmacology (01.07.2010)
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P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP
Cockayne, Debra A., Dunn, Philip M., Zhong, Yu, Rong, Weifang, Hamilton, Sara G., Knight, Gillian E., Ruan, Huai‐Zhen, Ma, Bei, Yip, Ping, Nunn, Philip, McMahon, Stephen B., Burnstock, Geoffrey, Ford, Anthony P. D. W.
Published in The Journal of physiology (01.09.2005)
Published in The Journal of physiology (01.09.2005)
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Gefapixant, a P2X3 receptor antagonist, for the treatment of refractory or unexplained chronic cough: a randomised, double-blind, controlled, parallel-group, phase 2b trial
Smith, Jaclyn A, Kitt, Michael M, Morice, Alyn H, Birring, Surinder S, McGarvey, Lorcan P, Sher, Mandel R, Li, Yu-Ping, Wu, Wen-Chi, Xu, Zhi Jin, Muccino, David R, Ford, Anthony P
Published in The lancet respiratory medicine (01.08.2020)
Published in The lancet respiratory medicine (01.08.2020)
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Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia
Swaminathan, Srividya, Klemm, Lars, Park, Eugene, Papaemmanuil, Elli, Ford, Anthony, Kweon, Soo-Mi, Trageser, Daniel, Hasselfeld, Brian, Henke, Nadine, Mooster, Jana, Geng, Huimin, Schwarz, Klaus, Kogan, Scott C, Casellas, Rafael, Schatz, David G, Lieber, Michael R, Greaves, Mel F, Müschen, Markus
Published in Nature immunology (01.07.2015)
Published in Nature immunology (01.07.2015)
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Overexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function
Schnegelsberg, Birthe, Sun, Tung-Tien, Cain, Gary, Bhattacharya, Anindya, Nunn, Philip A, Ford, Anthony P D W, Vizzard, Margaret A, Cockayne, Debra A
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.03.2010)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.03.2010)
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P2X3 receptor antagonism attenuates the progression of heart failure
Lataro, Renata M., Moraes, Davi J. A., Gava, Fabio N., Omoto, Ana C. M., Silva, Carlos A. A., Brognara, Fernanda, Alflen, Lais, Brazão, Vânia, Colato, Rafaela Pravato, do Prado, José Clóvis, Ford, Anthony P., Salgado, Helio C., Paton, Julian F. R.
Published in Nature communications (28.03.2023)
Published in Nature communications (28.03.2023)
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Postsynaptic P2X3‐containing receptors in gustatory nerve fibres mediate responses to all taste qualities in mice
Vandenbeuch, Aurelie, Larson, Eric D., Anderson, Catherine B., Smith, Steven A., Ford, Anthony P., Finger, Thomas E., Kinnamon, Sue C.
Published in The Journal of physiology (01.03.2015)
Published in The Journal of physiology (01.03.2015)
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Isoproterenol acts as a biased agonist of the alpha-1A-adrenoceptor that selectively activates the MAPK/ERK pathway
Copik, Alicja J, Baldys, Aleksander, Nguyen, Khanh, Sahdeo, Sunil, Ho, Hoangdung, Kosaka, Alan, Dietrich, Paul J, Fitch, Bill, Raymond, John R, Ford, Anthony P D W, Button, Donald, Milla, Marcos E
Published in PloS one (21.01.2015)
Published in PloS one (21.01.2015)
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Single-cell mutational profiling and clonal phylogeny in cancer
Potter, Nicola E, Ermini, Luca, Papaemmanuil, Elli, Cazzaniga, Giovanni, Vijayaraghavan, Gowri, Titley, Ian, Ford, Anthony, Campbell, Peter, Kearney, Lyndal, Greaves, Mel
Published in Genome research (01.12.2013)
Published in Genome research (01.12.2013)
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