Long-Term Stabilization of Maleimide–Thiol Conjugates
Fontaine, Shaun D, Reid, Ralph, Robinson, Louise, Ashley, Gary W, Santi, Daniel V
Published in Bioconjugate chemistry (21.01.2015)
Published in Bioconjugate chemistry (21.01.2015)
Get full text
Journal Article
A reactivity-based probe of the intracellular labile ferrous iron pool
Spangler, Benjamin, Morgan, Charles W, Fontaine, Shaun D, Vander Wal, Mark N, Chang, Christopher J, Wells, James A, Renslo, Adam R
Published in Nature chemical biology (01.09.2016)
Published in Nature chemical biology (01.09.2016)
Get full text
Journal Article
Long-Acting Poly(ADP-ribose) Polymerase Inhibitor Prodrug for Humans
Carreras, Christopher W., Fontaine, Shaun D., Reid, Ralph R., Ashley, Gary W., Santi, Daniel V.
Published in Bioconjugate chemistry (17.04.2024)
Published in Bioconjugate chemistry (17.04.2024)
Get full text
Journal Article
A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models
Spangler, Benjamin, Fontaine, Shaun D, Shi, Yihui, Sambucetti, Lidia, Mattis, Aras N, Hann, Byron, Wells, James A, Renslo, Adam R
Published in Journal of medicinal chemistry (22.12.2016)
Published in Journal of medicinal chemistry (22.12.2016)
Get full text
Journal Article
Prostate-Specific Membrane Antigen Targeted Deep Tumor Penetration of Polymer Nanocarriers
Meher, Niranjan, Ashley, Gary W., Bidkar, Anil P., Dhrona, Suchi, Fong, Cyril, Fontaine, Shaun D., Beckford Vera, Denis R., Wilson, David M., Seo, Youngho, Santi, Daniel V., VanBrocklin, Henry F., Flavell, Robert R.
Published in ACS applied materials & interfaces (16.11.2022)
Published in ACS applied materials & interfaces (16.11.2022)
Get full text
Journal Article
PET Imaging of the EPR Effect in Tumor Xenografts Using Small 15 nm Diameter Polyethylene Glycols Labeled with Zirconium-89
Beckford Vera, Denis R, Fontaine, Shaun D, VanBrocklin, Henry F, Hearn, Brian R, Reid, Ralph, Ashley, Gary W, Santi, Daniel V
Published in Molecular cancer therapeutics (01.02.2020)
Published in Molecular cancer therapeutics (01.02.2020)
Get full text
Journal Article
High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations
Mott, Bryan T., Eastman, Richard T., Guha, Rajarshi, Sherlach, Katy S., Siriwardana, Amila, Shinn, Paul, McKnight, Crystal, Michael, Sam, Lacerda-Queiroz, Norinne, Patel, Paresma R., Khine, Pwint, Sun, Hongmao, Kasbekar, Monica, Aghdam, Nima, Fontaine, Shaun D., Liu, Dongbo, Mierzwa, Tim, Mathews-Griner, Lesley A., Ferrer, Marc, Renslo, Adam R., Inglese, James, Yuan, Jing, Roepe, Paul D., Su, Xin-zhuan, Thomas, Craig J.
Published in Scientific reports (25.09.2015)
Published in Scientific reports (25.09.2015)
Get full text
Journal Article
A Very Long-Acting PARP Inhibitor Suppresses Cancer Cell Growth in DNA Repair-Deficient Tumor Models
Fontaine, Shaun D, Ashley, Gary W, Houghton, Peter J, Kurmasheva, Raushan T, Diolaiti, Morgan, Ashworth, Alan, Peer, Cody J, Nguyen, Ryan, Figg, Sr, William D, Beckford-Vera, Denis R, Santi, Daniel V
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Get full text
Journal Article
PET Imaging Using 89Zr Labeled StarPEG Nanocarriers Reveals Heterogeneous Enhanced Permeability and Retention (EPR) in Prostate Cancer
Meher, Niranjan, Bidkar, Anil P, Wadhwa, Anju, Bobba, Kondapa Naidu, Dhrona, Suchi, Dasari, Chandrashekhar, Mu, Changhua, Fong, Cyril O Y, Cámara, Juan A, Ali, Umama, Basak, Megha, Bulkley, David, Steri, Veronica, Fontaine, Shaun D, Zhu, Jun, Oskowitz, Adam, Aggarwal, Rahul R, Sriram, Renuka, Chou, Jonathan, Wilson, David M, Seo, Youngho, Santi, Daniel V, Ashley, Gary W, VanBrocklin, Henry F, Flavell, Robert R
Published in Molecular cancer therapeutics (27.09.2024)
Published in Molecular cancer therapeutics (27.09.2024)
Get full text
Journal Article
PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM -Deficient Tumors and Potent Synergy With PARP Inhibitors
Thomas, Anish, Fontaine, Shaun D., Diolaiti, Morgan E., Desai, Parth, Kumar, Rajesh, Takahashi, Nobuyuki, Sciuto, Linda, Nichols, Samantha, Ashworth, Alan, Feng, Felix Y., Ashley, Gary W., Nguyen, Minh, Pommier, Yves, Santi, Daniel V.
Published in Molecular cancer therapeutics (03.11.2022)
Published in Molecular cancer therapeutics (03.11.2022)
Get full text
Journal Article
Prospective use of the single-mouse experimental design for the evaluation of PLX038A
Ghilu, Samson, Li, Qilin, Fontaine, Shaun D., Santi, Daniel V., Kurmasheva, Raushan T., Zheng, Siyuan, Houghton, Peter J.
Published in Cancer chemotherapy and pharmacology (01.02.2020)
Published in Cancer chemotherapy and pharmacology (01.02.2020)
Get full text
Journal Article
Primary deuterium kinetic isotope effects prolong drug release and polymer biodegradation in a drug delivery system
Hearn, Brian R., Fontaine, Shaun D., Pfaff, Samuel J., Schneider, Eric L., Henise, Jeff, Ashley, Gary W., Santi, Daniel V.
Published in Journal of controlled release (28.05.2018)
Published in Journal of controlled release (28.05.2018)
Get full text
Journal Article
Species-specific optimization of PEG~SN-38 prodrug pharmacokinetics and antitumor effects in a triple-negative BRCA1-deficient xenograft
Fontaine, Shaun D., Hann, Byron, Reid, Ralph, Ashley, Gary W., Santi, Daniel. V.
Published in Cancer chemotherapy and pharmacology (01.10.2019)
Published in Cancer chemotherapy and pharmacology (01.10.2019)
Get full text
Journal Article
PEGylated talazoparib enhances therapeutic window of its combination with temozolomide in Ewing sarcoma
Del Pozo, Vanessa, Robles, Andrew J., Fontaine, Shaun D., Liu, Qianqian, Michalek, Joel E., Houghton, Peter J., Kurmasheva, Raushan T.
Published in iScience (18.02.2022)
Published in iScience (18.02.2022)
Get full text
Journal Article
A Very Long-acting Exatecan and Its Synergism with DNA Damage Response Inhibitors
Fontaine, Shaun D, Carreras, Christopher W, Reid, Ralph R, Ashley, Gary W, Santi, Daniel V
Published in Cancer research communications (01.05.2023)
Published in Cancer research communications (01.05.2023)
Get full text
Journal Article
Approach for Half-Life Extension of Small Antibody Fragments That Does Not Affect Tissue Uptake
Schneider, Eric L, Hearn, Brian R, Pfaff, Samuel J, Fontaine, Shaun D, Reid, Ralph, Ashley, Gary W, Grabulovski, Stefanie, Strassberger, Verena, Vogt, Lorenz, Jung, Thomas, Santi, Daniel V
Published in Bioconjugate chemistry (19.10.2016)
Published in Bioconjugate chemistry (19.10.2016)
Get full text
Journal Article
Drug Delivery to the Malaria Parasite Using an Arterolane-Like Scaffold
Fontaine, Shaun D., Spangler, Benjamin, Gut, Jiri, Lauterwasser, Erica M. W., Rosenthal, Philip J., Renslo, Adam R.
Published in ChemMedChem (01.01.2015)
Published in ChemMedChem (01.01.2015)
Get full text
Journal Article