Phototoxic action spectrum on a retinal pigment epithelium model of age-related macular degeneration exposed to sunlight normalized conditions
Arnault, Emilie, Barrau, Coralie, Nanteau, Céline, Gondouin, Pauline, Bigot, Karine, Viénot, Françoise, Gutman, Emmanuel, Fontaine, Valérie, Villette, Thierry, Cohen-Tannoudji, Denis, Sahel, José-Alain, Picaud, Serge
Published in PloS one (23.08.2013)
Published in PloS one (23.08.2013)
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RAR Inhibitors Display Photo-Protective and Anti-Inflammatory Effects in A2E Stimulated RPE Cells In Vitro through Non-Specific Modulation of PPAR or RXR Transactivation
Fontaine, Valérie, Boumedine, Thinhinane, Monteiro, Elodie, Fournié, Mylène, Gersende, Gendre, Sahel, José-Alain, Picaud, Serge, Veillet, Stanislas, Lafont, René, Latil, Mathilde, Dilda, Pierre J, Camelo, Serge
Published in International journal of molecular sciences (01.03.2024)
Published in International journal of molecular sciences (01.03.2024)
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Anti-Inflammatory Effects and Photo- and Neuro-Protective Properties of BIO203, a New Amide Conjugate of Norbixin, in Development for the Treatment of Age-Related Macular Degeneration (AMD)
Fontaine, Valérie, Balducci, Christine, Dinan, Laurence, Monteiro, Elodie, Boumedine, Thinhinane, Fournié, Mylène, Nguyen, Vincent, Guibout, Louis, Clatot, Justine, Latil, Mathilde, Veillet, Stanislas, Sahel, José-Alain, Lafont, René, Dilda, Pierre J, Camelo, Serge
Published in International journal of molecular sciences (01.03.2023)
Published in International journal of molecular sciences (01.03.2023)
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Retinal atrophy, inflammation, phagocytic and metabolic disruptions develop in the MerTK-cleavage-resistant mouse model
Enderlin, Julie, Rieu, Quentin, Réty, Salomé, Vanoni, Elora M, Roux, Solène, Dégardin, Julie, César, Quénol, Augustin, Sébastien, Nous, Caroline, Cai, Bishuang, Fontaine, Valérie, Sennlaub, Florian, Nandrot, Emeline F
Published in Frontiers in neuroscience (12.04.2024)
Published in Frontiers in neuroscience (12.04.2024)
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Journal Article
Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo
Fontaine, Valérie, Monteiro, Elodie, Brazhnikova, Elena, Lesage, Laëtitia, Balducci, Christine, Guibout, Louis, Feraille, Laurence, Elena, Pierre-Paul, Sahel, José-Alain, Veillet, Stanislas, Lafont, René
Published in PloS one (16.12.2016)
Published in PloS one (16.12.2016)
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Cone-Enriched Cultures from the Retina of Chicken Embryos to Study Rod to Cone Cellular Interactions
Millet-Puel, Géraldine, Pinault, Myriam, Cordonnier, Marie, Fontaine, Valérie, Sahel, José-Alain, Léveillard, Thierry
Published in Journal of visualized experiments (20.03.2021)
Published in Journal of visualized experiments (20.03.2021)
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Identification of an Alternative Splicing Product of the Otx2 Gene Expressed in the Neural Retina and Retinal Pigmented Epithelial Cells
Kole, Christo, Berdugo, Naomi, Da Silva, Corinne, Aït-Ali, Najate, Millet-Puel, Géraldine, Pagan, Delphine, Blond, Frédéric, Poidevin, Laetitia, Ripp, Raymond, Fontaine, Valérie, Wincker, Patrick, Zack, Donald J, Sahel, José-Alain, Poch, Olivier, Léveillard, Thierry
Published in PloS one (17.03.2016)
Published in PloS one (17.03.2016)
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Rodent Models of Retinal Degeneration: From Purified Cells in Culture to Living Animals
Fradot, Valérie, Augustin, Sébastien, Fontaine, Valérie, Marazova, Katia, Guillonneau, Xavier, Sahel, José A, Picaud, Serge
Published in Cold Spring Harbor perspectives in biology (01.10.2024)
Published in Cold Spring Harbor perspectives in biology (01.10.2024)
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Journal Article
A2E-induced inflammation and angiogenesis in RPE cells in vitro are modulated by PPAR-α, -β/δ, -γ, and RXR antagonists and by norbixin
Fontaine, Valérie, Fournié, Mylène, Monteiro, Elodie, Boumedine, Thinhinane, Balducci, Christine, Guibout, Louis, Latil, Mathilde, Sahel, José-Alain, Veillet, Stanislas, Dilda, Pierre J, Lafont, René, Camelo, Serge
Published in Aging (Albany, NY.) (20.09.2021)
Published in Aging (Albany, NY.) (20.09.2021)
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Functional Cone Rescue by RdCVF Protein in a Dominant Model of Retinitis Pigmentosa
Yang, Ying, Mohand-Said, Saddek, Danan, Aude, Simonutti, Manuel, Fontaine, Valérie, Clerin, Emmanuelle, Picaud, Serge, Léveillard, Thierry, Sahel, José-Alain
Published in Molecular therapy (01.05.2009)
Published in Molecular therapy (01.05.2009)
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Specific EEG resting state biomarkers in FXS and ASD
Proteau-Lemieux, Mélodie, Knoth, Inga Sophia, Davoudi, Saeideh, Martin, Charles-Olivier, Bélanger, Anne-Marie, Fontaine, Valérie, Côté, Valérie, Agbogba, Kristian, Vachon, Keely, Whitlock, Kerri, Biag, Hazel Maridith Barlahan, Thurman, Angela John, Rosenfelt, Cory, Tassone, Flora, Frei, Julia, Capano, Lucia, Abbeduto, Leonard, Jacquemont, Sébastien, Hessl, David, Hagerman, Randi Jenssen, Schneider, Andrea, Bolduc, Francois, Anagnostou, Evdokia, Lippe, Sarah
Published in Journal of neurodevelopmental disorders (09.09.2024)
Published in Journal of neurodevelopmental disorders (09.09.2024)
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Neurodegenerative and Neuroprotective Effects of Tumor Necrosis Factor (TNF) in Retinal Ischemia: Opposite Roles of TNF Receptor 1 and TNF Receptor 2
Fontaine, Valerie, Mohand-Said, Saddek, Hanoteau, Noelle, Fuchs, Celine, Pfizenmaier, Klaus, Eisel, Ulrich
Published in The Journal of neuroscience (01.04.2002)
Published in The Journal of neuroscience (01.04.2002)
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Abstract 13213: Performance of a Modified RAISE Score to Screen for Cardiac Amyloidosis in Patients Undergoing Transcatheter Aortic Valve Implantation
Zenses, Anne-Sophie, Bechard, Stephanie, Fontaine, Valérie, Mansour, Mohamad J, Remillard, Emilie, Carrier, Zoe, Forcillo, Jessica, Masson, Jean-Bernard, Potvin, Jeannot, Gobeil, Jean-François, Juneau, Daniel, Ribeiro, Paula A, Argentin, Stefania, Tournoux, Francois
Published in Circulation (New York, N.Y.) (08.11.2022)
Published in Circulation (New York, N.Y.) (08.11.2022)
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Journal Article
Cone-Enriched Cultures from the Retina of Chicken Embryos to Study Rod to Cone Cellular Interactions
Millet-Puel, Géraldine, Pinault, Myriam, Cordonnier, Marie, Fontaine, Valérie, Sahel, José-Alain, Léveillard, Thierry
Published in Journal of visualized experiments (20.03.2021)
Published in Journal of visualized experiments (20.03.2021)
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Journal Article
Vibratome sectioning mouse retina to prepare photoreceptor cultures
Clérin, Emmanuelle, Yang, Ying, Forster, Valérie, Fontaine, Valérie, Sahel, José-Alain, Léveillard, Thierry
Published in Journal of visualized experiments (22.12.2014)
Published in Journal of visualized experiments (22.12.2014)
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Journal Article
In vitro and in vivo characterization of BIO203, a new amide norbixin conjugate with improved pharmacokinetic profile. Potential for oral treatment of age‐related retinal degeneration
Fontaine, Valérie, Camelo, Serge, Christine, Balducci, Laurence, Dinan, Monteiro, Elodie, Boumedine, Thinhinane, Nguyen, Vincent, Fournié, Mylene, Clatot, Justine, Latil, Mathilde, Veillet, Stanislas, Lafont, René, Dilda, Pierre
Published in Acta ophthalmologica (Oxford, England) (01.12.2022)
Published in Acta ophthalmologica (Oxford, England) (01.12.2022)
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Journal Article
Systemic administration of the di-apocarotenoid norbixin (BIO201) is neuroprotective, preserves photoreceptor function and inhibits A2E and lipofuscin accumulation in animal models of age-related macular degeneration and Stargardt disease
Fontaine, Valérie, Monteiro, Elodie, Fournié, Mylène, Brazhnikova, Elena, Boumedine, Thinhinane, Vidal, Cécile, Balducci, Christine, Guibout, Louis, Latil, Mathilde, Dilda, Pierre J, Veillet, Stanislas, Sahel, José-Alain, Lafont, René, Camelo, Serge
Published in Aging (Albany, NY.) (07.04.2020)
Published in Aging (Albany, NY.) (07.04.2020)
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Journal Article
Phototoxic Action Spectrum on a Retinal Pigment Epithelium Model of Age-Related Macular Degeneration Exposed to Sunlight Normalized Conditions
Arnault, Emilie, Barrau, Coralie, Nanteau, Céline, Gondouin, Pauline, Bigot, Karine, Viénot, Françoise, Gutman, Emmanuel, Fontaine, Valérie, Villette, Thierry, Cohen-Tannoudji, Denis, Sahel, José-Alain, Picaud, Serge, Lewin, Alfred
Published in PloS one (23.08.2013)
Published in PloS one (23.08.2013)
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Journal Article