JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson’s disease: Mitochondrial protection and antioxidant properties
Fonseca-Fonseca, Luis Arturo, da Silva, Víctor Diogenes Amaral, Wong-Guerra, Maylin, Ramírez-Sánchez, Jeney, Yaquis, Alejandro Saúl Padrón, Ochoa-Rodríguez, Estael, Verdecia-Reyes, Yamila, de Araújo, Fillipe Mendes, Santana, Rejane Conceição, Outeiro, Tiago Fleming, Costa, Silvia Lima, Núñez-Figueredo, Yanier
Published in Neurotoxicology (Park Forest South) (01.01.2021)
Published in Neurotoxicology (Park Forest South) (01.01.2021)
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Journal Article
Novel arylidene malonate derivative, KM-34, showed neuroprotective effects on in vitro and in vivo models of ischemia/reperfusion
Ramírez-Sánchez, Jeney, Wong-Guerra, Maylin, Fonseca-Fonseca, Luis Arturo, Simões-Pires, Elisa Nicoloso, García-Pupo, Laura, Ochoa-Rodríguez, Estael, Verdecia-Reyes, Yamila, Delgado-Hernández, René, Salbego, Christianne, Souza, Diogo O., Pardo-Andreu, Gilberto L., Nuñez-Figueredo, Yanier
Published in European journal of pharmacology (15.05.2021)
Published in European journal of pharmacology (15.05.2021)
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Journal Article
JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats
Wong-Guerra, Maylin, Montano-Peguero, Yanay, Ramírez-Sánchez, Jeney, Jiménez-Martin, Javier, Fonseca-Fonseca, Luis Arturo, Hernández-Enseñat, Daniela, Nonose, Yasmine, Valdés, Odalys, Mondelo-Rodriguez, Abel, Ortiz-Miranda, Yaquelin, Bergado, Gretchen, Carmenate, Tania, Soto del Valle, Roberto Menéndez, Pardo-Andreu, Gilberto, Outeiro, Tiago Fleming, Padrón-Yaquis, Alejandro Saúl, Martimbianco de Assis, Adriano, O Souza, Diogo, Nuñez-Figueredo, Yanier
Published in Neurotoxicology (Park Forest South) (01.12.2021)
Published in Neurotoxicology (Park Forest South) (01.12.2021)
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Journal Article
JM-20, a novel hybrid molecule, protects against rotenone-induced neurotoxicity in experimental model of Parkinson’s disease
Fonseca-Fonseca, Luis Arturo, Wong-Guerra, Maylin, Ramírez-Sánchez, Jeney, Montano-Peguero, Yanay, Padrón Yaquis, Alejandro Saúl, Rodríguez, Abel Mondelo, da Silva, Víctor Diógenes Amaral, Costa, Silvia Lima, Pardo-Andreu, Gilberto L., Núñez-Figueredo, Yanier
Published in Neuroscience letters (18.01.2019)
Published in Neuroscience letters (18.01.2019)
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Journal Article
Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway
Ramírez-Sánchez, Jeney, Simões Pires, Elisa Nicoloso, Nuñez-Figueredo, Yanier, Pardo-Andreu, Gilberto L., Fonseca-Fonseca, Luis Arturo, Ruiz-Reyes, Alberto, Ochoa-Rodríguez, Estael, Verdecia-Reyes, Yamila, Delgado-Hernández, René, Souza, Diogo O., Salbego, Christianne
Published in Neurochemistry international (01.11.2015)
Published in Neurochemistry international (01.11.2015)
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Journal Article
KM-34, a Novel Antioxidant Compound, Protects against 6-Hydroxydopamine-Induced Mitochondrial Damage and Neurotoxicity
Fonseca-Fonseca, Luis Arturo, Nuñez-Figueredo, Yanier, Sánchez, Jeney Ramírez, Guerra, Maylin Wong, Ochoa-Rodríguez, Estael, Verdecia-Reyes, Yamila, Hernádez, René Delgado, Menezes-Filho, Noelio J., Costa, Teresa Cristina Silva, de Santana, Wagno Alcântara, Oliveira, Joana L., Segura-Aguilar, Juan, da Silva, Victor Diogenes Amaral, Costa, Silva Lima
Published in Neurotoxicity research (01.08.2019)
Published in Neurotoxicity research (01.08.2019)
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Journal Article
JM-20 protects memory acquisition and consolidation on scopolamine model of cognitive impairment
Wong-Guerra, Maylin, Jiménez-Martin, Javier, Fonseca-Fonseca, Luis Arturo, Ramírez-Sánchez, Jeney, Montano-Peguero, Yanay, Rocha, Joao Batista, D Avila, Fernanda, de Assis, Adriano M, Souza, Diogo Onofre, Pardo-Andreu, Gilberto L, Del Valle, Roberto Menéndez-Soto, Lopez, Guillermo Aparicio, Martínez, Odalys Valdés, García, Nelson Merino, Mondelo-Rodríguez, Abel, Padrón-Yaquis, Alejandro Saúl, Nuñez-Figueredo, Yanier
Published in Neurological research (New York) (04.05.2019)
Published in Neurological research (New York) (04.05.2019)
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Journal Article
Corrigendum to “JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats” [Neurotoxicology 87 (2021) 70–85]
Wong-Guerra, Maylin, Montano-Peguero, Yanay, Ramírez-Sánchez, Jeney, Jiménez-Martin, Javier, Fonseca-Fonseca, Luis Arturo, Hernández-Enseñat, Daniela, Nonose, Yasmine, Valdés, Odalys, Mondelo-Rodriguez, Abel, Ortiz-Miranda, Yaquelin, Bergado, Gretchen, Carmenate, Tania, Soto del Valle, Roberto Menéndez, Pardo-Andreu, Gilberto, Outeiro, Tiago Fleming, Padrón-Yaquis, Alejandro Saúl, de Assis, Adriano Martimbianco, Souza, Diogo O., Nuñez-Figueredo, Yanier
Published in Neurotoxicology (Park Forest South) (01.12.2023)
Published in Neurotoxicology (Park Forest South) (01.12.2023)
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Journal Article
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species
Santos, Cleonice Creusa, Cardim-Pires, Thyago R., Shvachiy, Liana, Fonseca-Fonseca, Luis Arturo, Muñoz, Patricia, Almeida, Áurea Maria A. N., Costa, Ana Carla S., Teles-Souza, Jéssica, Ochoa-Rodríguez, Estael, de Fátima Dias Costa, Maria, Palhano, Fernando L., Segura-Aguilar, Juan, Barbosa, Deyse B., do Bomfim, Mayra R., dos Santos Junior, Manoelito C., Leite, Franco Henrique A., da Rocha Pita, Samuel Silva, Costa, Silvia Lima, Núñez-Figueredo, Yanier, Outeiro, Tiago Fleming, Foguel, Débora, Silva, Victor Diogenes Amaral
Published in Neurotoxicity research (01.12.2022)
Published in Neurotoxicity research (01.12.2022)
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Journal Article
USE OF A FLAVANOID EXTRACT OBTAINED FROM THE SPECIES TALIPARITI ELATUM SW, FORMULATIONS COMPRISING SAME AND TREATMENT METHOD
FONSECA FONSECA, Luis Arturo, PADRON YAQUIS, Alejandro Saul, BARRIOS SARMIENTO, Maydel, RAMIREZ SANCHEZ, Jeney, WONG GUERRA, Maylin, MONTANO PEGUERO, Yanay, INFANTE BLANCO, Loraine Licet, NÚÑEZ FIGUEREDO, Yanier, ROMERO DIAZ, Jacqueline Aylema
Year of Publication 18.04.2024
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Year of Publication 18.04.2024
Patent
Benzodiazepine derivative with activity on the central nervous and vascular systems
Fonseca Fonseca, Luis Arturo, Wong Guerra, Maylin, Ramírez Sánchez, Jeney, Bárzaga Fernández, Pedro Gilberto, Padrón Yaquis, Alejandro Saúl, Garrido Suárez, Bárbara Beatriz, Delgado Hernández, René, Verdecia Reyes, Yamila, González Alfonso, Nicté, Núñez Figueredo, Yanier, Ochoa Rodríguez, Estael, Pardo Andreu, Gilberto Lázaro
Year of Publication 23.02.2024
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Year of Publication 23.02.2024
Patent
BENZODIAZEPINE DERIVATIVE WITH ACTIVITY ON THE CENTRAL NERVOUS AND VASCULAR SYSTEMS
DELGADO HERNANDEZ, RENE, PARDO ANDREU, GILBERTO LAZARO, NUNEZ FIGUEREDO, YANIER, GONZALEZ ALFONSO, NICTE, VERDECIA REYES, YAMILA, OCHOA RODRIGUEZ, ESTAEL, RAMIREZ SANCHEZ, JENEY, PADRON YAQUIS, SAUL ALEJANDRO, BARZAGA FERNANDEZ, PEDRO GILBERTO, WONG GUERRA, MAYLIN, FONSECA FONSECA, LUIS ARTURO, GARRIDO SUAREZ, BARBARA BEATRIZ
Year of Publication 18.07.2023
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Year of Publication 18.07.2023
Patent
BENZODIAZEPINE DERIVATIVE WITH ACTIVITY ON THE CENTRAL NERVOUS AND VASCULAR SYSTEMS
GONZALEZ ALFONSO Nicte, FONSECA FONSECA Luis Arturo, OCHOA RODRIGUEZ Estael, GARRIDO SUAREZ Barbara Beatriz, DELGADO HERNANDEZ Rene, NUNEZ FIGUEREDO Yanier, PARDO ANDREU Gilberto Lazaro, VERDECIA REYES Yamila, PADRON YAQUIS Alejandro Saul, BARZAGA FERNANDEZ Pedro Gilberto, RAMIREZ SANCHEZ Jeney, WONG GUERRA Maylin
Year of Publication 31.03.2022
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Year of Publication 31.03.2022
Patent
BENZODIAZEPINDERIVAT MED AKTIVITET PÅ CENTRALNERVE- OG KARSYSTEMERNE
FONSECA FONSECA, Luis Arturo, VERDECIA REYES, Yamila, DELGADO HERNÁNDEZ, René, RAMÍREZ SÁNCHEZ, Jeney, PADRÓN YAQUIS, Alejandro Saúl, WONG GUERRA, Maylin, PARDO ANDREU, Gilberto Lázaro, GARRIDO SUÁREZ, Bárbara Beatriz, NÚÑEZ FIGUEREDO, Yanier, OCHOA RODRÍGUEZ, Estael, BÁRZAGA FERNÁNDEZ, Pedro Gilberto, GONZÁLEZ ALFONSO, Nicté
Year of Publication 17.01.2022
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Year of Publication 17.01.2022
Patent
USE OF A FLAVONOID EXTRACT OBTAINED FROM THE SPECIES TALIPARITI ELATUM SW., FORMULATIONS COMPRISING SAME AND TREATMENT METHOD
FONSECA FONSECA, Luis Arturo, BARRIOS SARMIENTO, Maydel, RAMIREZ SANCHEZ, Jeney, PADRÓN YAQUIS, Alejandro Saúl, WONG GUERRA, Maylin, MONTANO PEGUERO, Yanay, INFANTE BLANCO, Loraine Licet, NÚÑEZ FIGUEREDO, Yanier, ROMERO DÍAZ, Jacqueline Aylema
Year of Publication 06.01.2022
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Year of Publication 06.01.2022
Patent
BENZODIAZEPINE DERIVATIVE WITH ACTIVITY ON THE CENTRAL NERVOUS AND VASCULAR SYSTEMS
FONSECA FONSECA, Luis Arturo, VERDECIA REYES, Yamila, DELGADO HERNÁNDEZ, René, RAMÍREZ SÁNCHEZ, Jeney, PADRÓN YAQUIS, Alejandro Saúl, WONG GUERRA, Maylin, PARDO ANDREU, Gilberto Lázaro, GARRIDO SUÁREZ, Bárbara Beatriz, NÚÑEZ FIGUEREDO, Yanier, OCHOA RODRÍGUEZ, Estael, BÁRZAGA FERNÁNDEZ, Pedro Gilberto, GONZÁLEZ ALFONSO, Nicté
Year of Publication 13.10.2021
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Year of Publication 13.10.2021
Patent
PHENOL COMPOUND AND COMBINATION OF SAME WITH A BENZODIAZEPINE FUSED TO 1,4-DIHYDROPYRIDINE FOR TREATING DISEASES OF THE CENTRAL NERVOUS AND VASCULAR SYSTEMS
DELGADO HERNANDEZ, RENE, PARDO ANDREU, GILBERTO LAZARO, NUNEZ FIGUEREDO, YANIER, CANAAN-HADEN NAVARRO, CLAUDIA AMANDA, VERDECIA REYES, YAMILA, OCHOA RODRIGUEZ, ESTAEL, RAMIREZ SANCHEZ, JENEY, MONDELO RODRIGUEZ, ABEL, WONG GUERRA, MAYLIN, GONZALEZ ALFONSO, NICTE, PADRON YAQUIS, ALEJANDRO SAUL, BARZAGA FERNANDEZ, PEDRO GILBERTO, FONSECA FONSECA, LUIS ARTURO
Year of Publication 30.08.2022
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Year of Publication 30.08.2022
Patent
BENZODIAZEPINE DERIVATIVE WITH ACTIVITY ON THE CENTRAL NERVOUS AND VASCULAR SYSTEMS
FONSECA FONSECA, Luis Arturo, VERDECIA REYES, Yamila, DELGADO HERNÁNDEZ, René, RAMÍREZ SÁNCHEZ, Jeney, PADRÓN YAQUIS, Saúl Alejandro, WONG GUERRA, Maylin, PARDO ANDREU, Gilberto Lázaro, GARRIDO SUÁREZ, Bárbara Beatriz, NÚÑEZ FIGUEREDO, Yanier, OCHOA RODRÍGUEZ, Estael, BÁRZAGA FERNÁNDEZ, Pedro Gilberto, GONZÁLEZ ALFONSO, Nicté
Year of Publication 25.08.2021
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Year of Publication 25.08.2021
Patent
Benzodiazepine product with activity on the central nervous and vascular systems
Fonseca Fonseca, Luis Arturo, Wong Guerra, Maylin, Ramírez Sánchez, Jeney, Bárzaga Fernández, Pedro Gilberto, Padrón Yaquis, Alejandro Saúl, Garrido Suárez, Bárbara Beatriz, Delgado Hernández, René, Verdecia Reyes, Yamila, González Alfonso, Nicté, Núñez Figueredo, Yanier, Ochoa Rodríguez, Estael, Pardo Andreu, Gilberto Lázaro
Year of Publication 24.08.2021
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Year of Publication 24.08.2021
Patent
Benzodiazepine derivative with activity on the central nervous and vascular systems
Fonseca Fonseca, Luis Arturo, Wong Guerra, Maylin, Ramírez Sánchez, Jeney, Bárzaga Fernández, Pedro Gilberto, Padrón Yaquis, Alejandro Saúl, Garrido Suárez, Bárbara Beatriz, Delgado Hernández, René, Verdecia Reyes, Yamila, González Alfonso, Nicté, Núñez Figueredo, Yanier, Ochoa Rodríguez, Estael, Pardo Andreu, Gilberto Lázaro
Year of Publication 05.08.2021
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Year of Publication 05.08.2021
Patent