Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy
Kober, Christina, Roewe, Julian, Schmees, Norbert, Roese, Lars, Roehn, Ulrike, Bader, Benjamin, Stoeckigt, Detlef, Prinz, Florian, Gorjánácz, Mátyás, Roider, Helge Gottfried, Olesch, Catherine, Leder, Gabriele, Irlbacher, Horst, Lesche, Ralf, Lefranc, Julien, Oezcan-Wahlbrink, Mine, Batra, Ankita Sati, Elmadany, Nirmeen, Carretero, Rafael, Sahm, Katharina, Oezen, Iris, Cichon, Frederik, Baumann, Daniel, Sadik, Ahmed, Opitz, Christiane A, Weinmann, Hilmar, Hartung, Ingo V, Kreft, Bertolt, Offringa, Rienk, Platten, Michael, Gutcher, Ilona
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
926 BAY 2965501: a highly selective DGK zeta inhibitor for cancer immunotherapy
Offringa, Rienk, Olesch, Catherine, Cichon, Frederik, Grees, Mareike, Schmees, Norbert, Roehn, Ulrike, Prinz, Florian, Stoeckigt, Detlef, Erkelenz, Michael, Uyen Nguyen, Thi Thanh, Boemer, Ulf, Günther, Judith, Kunze, Marc, Petersen, Kirstin, Kirchhoff, Dennis
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Believe it or not: how much can we rely on published data on potential drug targets?
Prinz, Florian, Schlange, Thomas, Asadullah, Khusru
Published in Nature reviews. Drug discovery (01.09.2011)
Published in Nature reviews. Drug discovery (01.09.2011)
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Journal Article
Caspase-8 and Apaf-1-independent Caspase-9 Activation in Sendai Virus-infected Cells
Bitzer, Michael, Armeanu, Sorin, Prinz, Florian, Ungerechts, Guy, Wybranietz, Wolfgang, Spiegel, Martin, Bernlöhr, Christian, Cecconi, Francesco, Gregor, Michael, Neubert, Wolfgang J., Schulze-Osthoff, Klaus, Lauer, Ulrich M.
Published in The Journal of biological chemistry (16.08.2002)
Published in The Journal of biological chemistry (16.08.2002)
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Journal Article
Sendai Virus Infection Induces Apoptosis through Activation of Caspase-8 (FLICE) and Caspase-3 (CPP32)
Bitzer, M, Prinz, F, Bauer, M, Spiegel, M, Neubert, W J, Gregor, M, Schulze-Osthoff, K, Lauer, U
Published in Journal of Virology (01.01.1999)
Published in Journal of Virology (01.01.1999)
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Journal Article
3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions
Wenzel, Carsten, Riefke, Björn, Gründemann, Stephan, Krebs, Alice, Christian, Sven, Prinz, Florian, Osterland, Marc, Golfier, Sven, Räse, Sebastian, Ansari, Nariman, Esner, Milan, Bickle, Marc, Pampaloni, Francesco, Mattheyer, Christian, Stelzer, Ernst H., Parczyk, Karsten, Prechtl, Stefan, Steigemann, Patrick
Published in Experimental cell research (15.04.2014)
Published in Experimental cell research (15.04.2014)
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Journal Article
Ultrasound of nerves of the lower extremities
Gehlen, Martin, Schwarz-Eywill, Michael, Mahn, Karin, Pfeiffer, Andreas, Prinz, Florian, Maier, Anna
Published in Zeitschrift für Rheumatologie (01.02.2024)
Published in Zeitschrift für Rheumatologie (01.02.2024)
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Journal Article
A genetics-led approach defines the drug target landscape of 30 immune-related traits
Fang, Hai, De Wolf, Hans, Knezevic, Bogdan, Burnham, Katie L., Osgood, Julie, Sanniti, Anna, Lledó Lara, Alicia, Kasela, Silva, De Cesco, Stephane, Wegner, Jörg K., Handunnetthi, Lahiru, McCann, Fiona E., Chen, Liye, Sekine, Takuya, Brennan, Paul E., Marsden, Brian D., Damerell, David, O’Callaghan, Chris A., Bountra, Chas, Bowness, Paul, Sundström, Yvonne, Milani, Lili, Berg, Louise, Göhlmann, Hinrich W., Peeters, Pieter J., Fairfax, Benjamin P., Sundström, Michael, Knight, Julian C.
Published in Nature genetics (01.07.2019)
Published in Nature genetics (01.07.2019)
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Journal Article
Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
Cossa, Giacomo, Roeschert, Isabelle, Prinz, Florian, Baluapuri, Apoorva, Silveira Vidal, Raphael, Schülein-Völk, Christina, Chang, Yun-Chien, Ade, Carsten Patrick, Mastrobuoni, Guido, Girard, Cyrille, Kumar, Amit, Wortmann, Lars, Walz, Susanne, Lührmann, Reinhard, Kempa, Stefan, Kuster, Bernhard, Wolf, Elmar, Mumberg, Dominik, Eilers, Martin
Published in Molecular cell (19.03.2020)
Published in Molecular cell (19.03.2020)
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Journal Article
Discovery of BAY-985, a Highly Selective TBK1/IKKε Inhibitor
Lefranc, Julien, Schulze, Volker Klaus, Hillig, Roman Christian, Briem, Hans, Prinz, Florian, Mengel, Anne, Heinrich, Tobias, Balint, Jozsef, Rengachari, Srinivasan, Irlbacher, Horst, Stöckigt, Detlef, Bömer, Ulf, Bader, Benjamin, Gradl, Stefan Nikolaus, Nising, Carl Friedrich, von Nussbaum, Franz, Mumberg, Dominik, Panne, Daniel, Wengner, Antje Margret
Published in Journal of medicinal chemistry (23.01.2020)
Published in Journal of medicinal chemistry (23.01.2020)
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Journal Article
Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2‑d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5
Nguyen, Duy, Lemos, Clara, Wortmann, Lars, Eis, Knut, Holton, Simon J, Boemer, Ulf, Moosmayer, Dieter, Eberspaecher, Uwe, Weiske, Joerg, Lechner, Christian, Prechtl, Stefan, Suelzle, Detlev, Siegel, Franziska, Prinz, Florian, Lesche, Ralf, Nicke, Barbara, Nowak-Reppel, Katrin, Himmel, Herbert, Mumberg, Dominik, von Nussbaum, Franz, Nising, Carl F, Bauser, Marcus, Haegebarth, Andrea
Published in Journal of medicinal chemistry (24.01.2019)
Published in Journal of medicinal chemistry (24.01.2019)
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Journal Article
Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription
Cossa, Giacomo, Roeschert, Isabelle, Prinz, Florian, Baluapuri, Apoorva, Vidal, Raphael Silveira, Schülein-Völk, Christina, Chang, Yun-Chien, Ade, Carsten Patrick, Mastrobuoni, Guido, Girard, Cyrille, Kumar, Amit, Wortmann, Lars, Walz, Susanne, Lührmann, Reinhard, Kempa, Stefan, Kuster, Bernhard, Wolf, Elmar, Mumberg, Dominik, Eilers, Martin
Published in Molecular cell (03.06.2021)
Published in Molecular cell (03.06.2021)
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Journal Article
Abstract 1470: Preclinical activity of the first reversible, potent and selective inhibitor of EGFR exon 20 insertions
Siegel, Franziska, Siegel, Stephan, Graham, Keith, Kaplan, Bethany, Petersen, Kirstin, Boemer, Ulf, Eberspaecher, Uwe, Korr, Daniel, Moenning, Ursula, Suelzle, Detlev, Schroeder, Jens, Prinz, Florian, Zitzmann-Kolbe, Sabine, Karsli-Uzunbas, Gizem, Lewis, Timothy, Hermsen, Mario, Cherniack, Andrew, von Nussbaum, Franz, Eis, Knut, Meyerson, Matthew, Greulich, Heidi
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor
Gutcher, Ilona, Kober, Christina, Roese, Lars, Roewe, Julian, Schmees, Norbert, Prinz, Florian, Gorjanacz, Matyas, Roehn, Ulrike, Bader, Benjamin, Irlbacher, Horst, Stoeckigt, Detlef, Carretero, Rafael, Sahm, Katharina, Oezen, Iris, Weinmann, Hilmar, Hartung, Ingo V., Kreft, Bertolt, Platten, Michael
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 5873: BAY-3827, a selective inhibitor of AMPK for the evaluation of the role of AMPK in Myc-dependent tumors
Lemos, Clara, Schulze, Volker K., Bader, Benjamin, Christ, Clara D., Briem, Hans, Politz, Oliver, Prinz, Florian, Holton, Simon, Heinrich, Tobias, Lefranc, Julien, Lienau, Philip, Scholz, Arne, Nussbaum, Franz von, Nising, Carl Friedrich, Mumberg, Dominik, Bauser, Marcus, Hägebarth, Andrea
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells
Prinz, Florian, Puetter, Vera, Holton, Simon J., Andres, Dorothee, Stegmann, Christian M., Kwiatkowski, Dennis, Prechtl, Stefan, Petersen, Kirstin, Beckmann, Georg, Kreft, Bertolt, Mumberg, Dominik, Fernández-Montalván, Amaury
Published in The Journal of biological chemistry (20.05.2016)
Published in The Journal of biological chemistry (20.05.2016)
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Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells
Raab, Monika, Kappel, Sven, Krämer, Andrea, Sanhaji, Mourad, Matthess, Yves, Kurunci-Csacsko, Elisabeth, Calzada-Wack, Julia, Rathkolb, Birgit, Rozman, Jan, Adler, Thure, Busch, Dirk H., Esposito, Irene, Fuchs, Helmut, Gailus-Durner, Valérie, Klingenspor, Martin, Wolf, Eckhard, Sänger, Nicole, Prinz, Florian, Angelis, Martin Hrabě de, Seibler, Jost, Yuan, Juping, Bergmann, Martin, Knecht, Rainald, Kreft, Bertolt, Strebhardt, Klaus
Published in Nature communications (19.07.2011)
Published in Nature communications (19.07.2011)
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Journal Article
Nervensonographie der unteren Extremitäten
Gehlen, Martin, Schwarz-Eywill, Michael, Mahn, Karin, Pfeiffer, Andreas, Prinz, Florian, Maier, Anna
Published in Zeitschrift für Rheumatologie (01.02.2024)
Published in Zeitschrift für Rheumatologie (01.02.2024)
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